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    COMPOSITIONS AND METHODS FOR TREATING MALIGNANT, AUTOIMMUNE AND INFLAMMATORY DISEASES
    275.
    发明申请
    COMPOSITIONS AND METHODS FOR TREATING MALIGNANT, AUTOIMMUNE AND INFLAMMATORY DISEASES 有权

    公开(公告)号：US20210052626A1

    公开(公告)日：2021-02-25

    申请号：US17089769

    申请日：2020-11-05

    Applicant: Yeda Research and Development Co. Ltd.

    Inventor： Idit SHACHAR ,  Hadas LEWINSKY ,  Lihi RADOMIR ,  Anna WIENER

    IPC: A61K31/713 ,  C07K16/28 ,  A61P37/06 ,  A61P35/02 ,  A61P29/00 ,  A61K38/17

    Abstract: A method of treating a malignant disease involving T cell exhaustion in a subject, with the proviso that said malignant disease is not a B cell malignancy, is disclosed. The method comprising administering to the subject a therapeutically effective amount of an agent capable of decreasing an activity or expression of CD84, thereby treating the malignant disease involving the T cell exhaustion. Also disclosed is a method of treating an autoimmune or inflammatory disease in a subject, the method comprising administering to a subject a therapeutically effective amount of an agent capable of decreasing an activity or expression of CD84. A method comprising administering to the subject a therapeutically effective amount of an agent capable of decreasing an activity or expression of SLAMF1, with the proviso that said agent is not an agent capable of decreasing an activity or expression of CD84, is also disclosed.

    METHODS AND SYSTEM FOR STIMULATING ROOT EXUDATION IN PLANTS
    278.
    发明申请
    METHODS AND SYSTEM FOR STIMULATING ROOT EXUDATION IN PLANTS 有权

    公开(公告)号：US20210007363A1

    公开(公告)日：2021-01-14

    申请号：US17040227

    申请日：2019-03-21

    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD

    Inventor： Asaph AHARONI ,  Elisa KORENBLUM

    IPC: A01N63/38 ,  C07D305/14 ,  C07J17/00 ,  A01N63/20 ,  A01G29/00

    Abstract: Provided is a plant exudate, methods for obtaining a plant exudate by inducing the plant to secrete an exudate and systems for the collection of a plant exudate which include: one or more plant container including at least two discrete compartments each configured to accommodate a split root of a plant, the compartments being a root stimulating compartment including one or more input being in fluid communication with at least a source of a plant root stimulant, and a root exudate harvesting compartment, and a root exudate collection compartment in fluid communication with the root exudate harvesting compartment.

    DEVICES AND METHODS TO MEASURE SMALL DISPLACEMENTS
    280.
    发明申请
    DEVICES AND METHODS TO MEASURE SMALL DISPLACEMENTS 审中-公开

    公开(公告)号：US20200378752A1

    公开(公告)日：2020-12-03

    申请号：US16071089

    申请日：2017-01-19

    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

    Inventor： Igor LUBOMIRSKY ,  Guy LAZOVSKI

    IPC: G01B11/16 ,  G01N25/16 ,  G01N21/21 ,  G01N21/17

    Abstract: Methods, devices and apparatus for measuring expansion/contraction properties of a material are described. According to an embodiment a method comprises: providing a device, said device comprising a sample comprising said material, said sample comprising a first surface and a second surface, a first substrate and a second substrate connected to said first surface and to said second surface of said sample, respectively, a reflective material attached to said second substrate, and two electrical contacts each independently in contact with said sample; applying voltage to said sample using said electrical contacts; illuminating said reflective material using a light source, such that said illumination comprises light having known and controllable polarization; collecting light reflected off said reflective material; measuring amplitude and phase of an oscillating change in polarization of the reflected light; and extracting parameters related to expansion/contraction from said reflected light measurement, thus evaluating said expansion/contraction properties of said material.

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