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公开(公告)号：US20100200745A1
公开(公告)日：2010-08-12
申请号：US12763092
申请日：2010-04-19
申请人： Mark A. Osgood , Ching Wu
发明人： Mark A. Osgood , Ching Wu
CPC分类号： H01J49/061 , C07B63/00 , G01N27/622 , Y10T29/49227
摘要： The present invention generally relates to systems and methods for transmitting beams of charged particles, and in particular to such systems and methods that employ defecting at least one set of grid elements into the same plane to form an ion gate. In addition, an operation method of closing a gate involving alternating voltages on the adjacent gate wires is described.
摘要翻译： 本发明一般涉及用于传送带电粒子束的系统和方法，特别涉及这样的系统和方法，该系统和方法使用将至少一组栅格元件缺陷到同一平面中以形成离子门。 此外，描述了在相邻栅极线上闭合涉及交流电压的栅极的操作方法。
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公开(公告)号：US20100108877A1
公开(公告)日：2010-05-06
申请号：US12610306
申请日：2009-10-31
申请人： Ching Wu , Clinton Alawn Krueger
发明人： Ching Wu , Clinton Alawn Krueger
IPC分类号： H01J49/02
CPC分类号： G01N27/622
摘要： The present invention describes separating components in a sample in an ion mobility based spectrometer using at least one matching property of the components other than the molecular properties in conventional ion mobility measurements in noble drift gases to enhance separation and resolution of the sample. Separation based on the matching property is realized by altering the drift media of the IMS. Besides altering drift media, energy level of ions and/or drift media are also controlled during the separation process. This invention describes an ion mobility apparatus wherein an energy source is added to the IMS that provides additional energy to the ions and/or drift media and tuning methods that involve selecting drift media and optimizing the energy level in order to achieve optimal performance.
摘要翻译： 本发明描述了使用离子迁移率光谱仪中的样品中的组分，其使用除贵族漂移气体中的常规离子迁移率测量中的分子特性以外的组分的至少一个匹配性质以增强样品的分离和分离。 通过改变IMS的漂移介质来实现基于匹配特性的分离。 除了改变漂移介质之外，还可以在分离过程中控制离子和/或漂移介质的能级。 本发明描述了一种离子迁移率装置，其中向IMS提供能量源，其为离子和/或漂移介质提供额外的能量以及涉及选择漂移介质并优化能级以便实现最佳性能的调谐方法。
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公开(公告)号：US07705296B2
公开(公告)日：2010-04-27
申请号：US11674646
申请日：2007-02-13
申请人： Ching Wu
发明人： Ching Wu
IPC分类号： H01J49/00
CPC分类号： G01N27/622 , H01J49/062
摘要： An ion mobility spectrometer includes a protective housing. A drift tube having at least one inlet and at least one outlet confines a drift gas. An ion gate is positioned in the drift tube. The ion gate defines a reaction region and a drift region in the drift tube. An ion detector is positioned in the drift tube downstream of the ion gate at an end of the drift region. A helical resistive wire coil is positioned around the drift tube. A power supply generates an electric field in the helical resistive wire coil that rapidly controls the temperature of the drift gas.
摘要翻译： 离子迁移谱仪包括保护壳体。 漂移管具有至少一个入口和至少一个出口限制漂移气体。 离子门位于漂移管中。 离子门限定了漂移管中的反应区和漂移区。 离子检测器位于漂移管的漂移区末端的离子门下游。 螺旋电阻线圈位于漂移管周围。 电源在螺旋电阻线圈中产生电场，其迅速地控制漂移气体的温度。
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公开(公告)号：US20080250877A1
公开(公告)日：2008-10-16
申请号：US11736233
申请日：2007-04-17
申请人： Ching Wu
发明人： Ching Wu
CPC分类号： G01N1/14 , G01N1/2214 , G01N1/405 , G01N2001/022 , G01N2001/028
摘要： This invention describes a sample collection method that could release and collect residues of explosives and other chemicals from a surface; the described method is implemented into a compact detection system that can be used as a “wand” for screening chemicals residues on a subject. The wand configuration includes multi-function for sampling and detecting multiple threads. The invention further describes a method of inspecting a subject using an interrogating apparatus in a sweeping motion; the near range closed loop particle sampling arrangement allows effective collection of particle and vapor residues from a targeted surface. The invention also describes a sampling and detecting apparatus for on-the-fly threat detection using compact ion mobility based detectors.
摘要翻译： 本发明描述了可从表面释放和收集爆炸物和其他化学物质的残留物的样品收集方法; 所描述的方法被实现为紧凑的检测系统，其可以用作筛选受试者上的化学物质残留物的“棒”。 魔杖配置包括用于采样和检测多个线程的多功能。 本发明还描述了一种使用询问装置以扫描运动来检查对象的方法; 近距离闭环颗粒采样装置允许从目标表面有效收集颗粒和蒸气残留物。 本发明还描述了一种用于使用基于紧密离子移动性的检测器进行飞行中威胁检测的采样和检测装置。
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25.发明申请公开(公告)号：US20180372684A1
公开(公告)日：2018-12-27
申请号：US16055038
申请日：2018-08-04
申请人： Ching Wu
发明人： Ching Wu
摘要： The present invention relates to drift tubes for ion mobility spectrometers. In one embodiment, the drift tube of the present invention uses a simplified design having helical resistive material to form substantially constant electric fields that guide ion movements. The drift tube for ion mobility spectrometers described herein is constructed with a non-conductive structure. This configuration provides a robust ion mobility spectrometer that is simple to build. One feature of the present invention is that the drift tube design described herein enables the ion mobility spectrometer to be built with a lower weight, lower power consumption, lower manufacturing cost, and free of sealants.
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26.发明授权公开(公告)号：US10073056B2
公开(公告)日：2018-09-11
申请号：US15383736
申请日：2016-12-19
申请人： Ching Wu
发明人： Ching Wu
摘要： The present invention relates to ion mobility spectrometers. In one embodiment, the ion mobility spectrometer of the present invention uses a simplified ion mobility spectrometer design having helical resistive material to form substantially constant electric fields that guide ion movements. The drift tube for ion mobility spectrometers described herein is constructed with a non-conductive structure. This configuration provides a robust ion mobility spectrometer that is simple to build. One feature of the present invention is that the drift tube design described herein enables the ion mobility spectrometer to be built with a lower weight, lower power consumption, lower manufacturing cost, and free of sealants.
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公开(公告)号：US09508536B2
公开(公告)日：2016-11-29
申请号：US14283499
申请日：2014-05-21
申请人： Ching Wu
发明人： Ching Wu
IPC分类号： H01J49/04
CPC分类号： H01J49/049
摘要： This invention describes a sample collection and desorption device and method that collects residues of explosives and other chemicals from a surface and then introduces them into a detector. The desorption method and device include introducing additional chemicals while heating up the sample collector, thus, the collected sample may be converted via a chemical reaction or a catalytic process. The detector can be an ion mobility spectrometer or mass spectrometer.
摘要翻译： 本发明描述了从表面收集炸药和其他化学物质的残留物并随后将其引入检测器的样品收集和解吸装置和方法。 解吸方法和装置包括在加热样品收集器的同时引入额外的化学品，因此，可以通过化学反应或催化过程转化收集的样品。 检测器可以是离子迁移谱仪或质谱仪。
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公开(公告)号：US09236234B2
公开(公告)日：2016-01-12
申请号：US14214558
申请日：2014-03-14
申请人： Ching Wu , Mark A Osgood
发明人： Ching Wu , Mark A Osgood
CPC分类号： H01J49/061 , C07B63/00 , G01N27/622 , H01J49/0027
摘要： The present invention uses an AC voltage instead of DC voltage on an ion gate to filter/selectively pass ions. The ions that pass through the AC ion gate can be further separated in a spectrometric instrument. An ion mobility spectrometer using the AC ion gate can achieve better gating performance. For a time of flight ion mobility spectrometer with an AC ion gate, a narrow pulse of selected ions can be passed into a drift tube where they are separated based on their low field ion mobility. Moreover, when the AC voltage at the AC ion gate has a waveform as used for differential ion mobility spectrometry, the time of flight ion mobility spectrometer is converted into a two dimensional separation spectrometer, where ions are first separated based on their high field ion mobility and then further separated based on their low field ion mobility.
摘要翻译： 本发明在离子浇口上使用交流电压而不是直流电压来过滤/选择性地通过离子。 通过AC离子浇口的离子可以在光谱仪器中进一步分离。 使用AC离子浇口的离子迁移谱仪可以获得更好的门控性能。 对于具有AC离子浇口的飞行时间离子迁移谱仪，选择的离子的窄脉冲可以被传送到漂移管中，基于它们的低场离子迁移率，它们被分离。 此外，当AC离子浇口处的AC电压具有用于差示离子迁移率光谱法的波形时，将飞行时间离子迁移谱仪转换成二维分离光谱仪，其中离子首先基于它们的高场离子迁移率而被分离 然后基于它们的低场离子迁移率进一步分离。
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公开(公告)号：US08884221B2
公开(公告)日：2014-11-11
申请号：US13475993
申请日：2012-05-20
CPC分类号： G01N27/622
摘要： An ion mobility spectrometer wherein ions are separated along a drift axis while providing a drift gas flow in a direction that is substantially neither in the direction of the drift axis nor opposite to the drift axis. An ion mobility spectrometer and operation methods use a cross-directional gas flow in a drift tube and/or a segmented drift tube for pre-separation.
摘要翻译： 离子迁移谱仪，其中离子沿着漂移轴线分离，同时在基本上不是在漂移轴线的方向上也不与漂移轴线相反的方向提供漂移气流。 离子迁移谱仪和操作方法在漂移管和/或分段漂移管中使用横向气流用于预分离。
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公开(公告)号：US08618476B2
公开(公告)日：2013-12-31
申请号：US13293317
申请日：2011-11-10
申请人： Ching Wu , Clinton Alawn Krueger
发明人： Ching Wu , Clinton Alawn Krueger
CPC分类号： G01N27/622
摘要： The present invention describes separating components in a sample in an ion mobility based spectrometer using at least one matching property of the components other than the molecular properties in conventional ion mobility measurements in noble drift gases to enhance separation and resolution of the sample. Separation based on the matching property is realized by altering the drift media of the IMS. Besides altering drift media, energy level of ions and/or drift media are also controlled during the separation process. This invention describes an ion mobility apparatus wherein an energy source is added to the IMS that provides additional energy to the ions and/or drift media and tuning methods that involve selecting drift media and optimizing the energy level in order to achieve optimal performance.
摘要翻译： 本发明描述了使用离子迁移率光谱仪中的样品中的组分，其使用除贵族漂移气体中的常规离子迁移率测量中的分子特性以外的组分的至少一个匹配性质以增强样品的分离和分离。 通过改变IMS的漂移介质来实现基于匹配特性的分离。 除了改变漂移介质之外，还可以在分离过程中控制离子和/或漂移介质的能级。 本发明描述了一种离子迁移率装置，其中向IMS提供能量源，其为离子和/或漂移介质提供额外的能量以及涉及选择漂移介质并优化能级以便实现最佳性能的调谐方法。
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