公开(公告)号：US11460440B2

公开(公告)日：2022-10-04

申请号：US17063636

申请日：2020-10-05

Applicant: Ching Wu

Inventor： Ching Wu

IPC: G01N27/622 ,  H01J49/00 ,  H01J49/06 ,  H01J49/04 ,  G01N30/08 ,  G01N1/40 ,  G01N30/00

Abstract: The present invention relates to a preconcentrator for vapors and particles collected from air. The vapor preconcentrator is made from plural layer of coils. The coil is made of resistance alloy. The pitch size of the coil is made to precisely trap/filter out certain size of the particles during preconcentration. Multiple coils could be made with different pitch sizes to achieve multiple step filtrations. When the sample flow enters the preconcentrator chamber, it passes through the coils. The particles of different sizes are trapped on different layer of coils. The vapor sample can be trapped on any coils when interacted with the coil surface. They could be trapped without any affinitive coating as the preconcentrator is at relatively low temperature. Different coils or different sections of the coil can be coated with different material to trap chemicals of different classes. During the desorption process, the coils are flash heated with controlled temperature ramping speed to evaporate the trapped chemicals. Various configurations, constructions, and methods of operation are presented.

公开(公告)号：US10049865B2

公开(公告)日：2018-08-14

申请号：US14703868

申请日：2015-05-04

Applicant: Mark A Osgood ,  Ching Wu

Inventor： Mark A Osgood ,  Ching Wu

IPC: H01J49/00 ,  C07B63/00 ,  G01N27/62 ,  H01J49/04 ,  H01J49/06

Abstract: The present invention relates to improving the ability of a hyphenated instrument to analyze a sample benefiting from having the first instrument's analysis of the same sample. A fast switching mechanism can be used as the interface between an ion mobility spectrometer (IMS) and a mass spectrometer (MS) such that the obtained IMS spectrum is converted into a timing diagram that controls the vacuum inlet's size dynamically during analysis of a neutral and/or charged chemical and/or biological species such that a smaller pumping system can be used.

公开(公告)号：US09941100B2

公开(公告)日：2018-04-10

申请号：US13328474

申请日：2011-12-16

Applicant: Wei-Ching Wu ,  Wen-Long Lee ,  Ding-I Liu

Inventor： Wei-Ching Wu ,  Wen-Long Lee ,  Ding-I Liu

IPC: H01J37/32 ,  C23C16/52 ,  C23C16/455

CPC classification number: H01J37/3244 ,  C23C16/45563 ,  C23C16/45589 ,  C23C16/52

Abstract: The description relates to an adjustable nozzle capable of pivoting about an axis of the nozzle and translating along the axis of the nozzle. A high density plasma chemical vapor deposition (HDP CVD) chamber houses a plurality of adjustable nozzles. A feedback control system includes a control unit coupled to the adjustable nozzle and the HDP CVD chamber to form a more uniform thickness profile of films deposited on a wafer in the HDP CVD chamber.

公开(公告)号：US20180067078A1

公开(公告)日：2018-03-08

申请号：US15713684

申请日：2017-09-24

Applicant: Ching Wu ,  Mark A. Osgood ,  Eugenie Hainsworth ,  Clinton Alawn Krueger ,  Taeman Kim

Inventor： Ching Wu ,  Mark A. Osgood ,  Eugenie Hainsworth ,  Clinton Alawn Krueger ,  Taeman Kim

IPC: G01N27/62

CPC classification number: G01N27/622

Abstract: The IMS apparatus and methods described in this invention involve setting the ion detector at the highest potential of the drift tube and setting the ionization source at ground or near ground potential. The methods allow significantly simple sample introduction without the limitation of the high potential (voltage) concern of the front end sample delivery. The invention also describes bringing samples directly into the ion mobility drift tube. The invention further describes using single syringe for sample introduction via an electrospray ionization method.

公开(公告)号：US09859105B2

公开(公告)日：2018-01-02

申请号：US14742653

申请日：2015-06-17

Applicant: Adam Michael Graichen ,  Robert H Jackson ,  Mark A Osgood ,  Ching Wu ,  Jianglin Wu

Inventor： Adam Michael Graichen ,  Robert H Jackson ,  Mark A Osgood ,  Ching Wu ,  Jianglin Wu

IPC: H01J49/00 ,  G01N27/62 ,  G01N30/72

CPC classification number: H01J49/0031 ,  G01N27/622 ,  G01N30/7233 ,  H01J49/004

Abstract: A second gate in an Ion Mobility Spectrometer is used to select or block different time windows of the ion mobility spectrum. A second gate in the Ion Mobility Mass Spectrometer is used to modulate peak intensities in the IMS spectrum, allowing each peak in the IMS spectrum to be unambiguously matched with its set of fragment ions in a subsequent MS-MS mass spectrum.

公开(公告)号：US09719963B2

公开(公告)日：2017-08-01

申请号：US14537863

申请日：2014-11-10

Applicant: Ching Wu ,  Clinton Alawn Krueger ,  Anthony Joseph Midey ,  Mark A Osgood

Inventor： Ching Wu ,  Clinton Alawn Krueger ,  Anthony Joseph Midey ,  Mark A Osgood

IPC: G01N27/62

CPC classification number: G01N27/622

Abstract: An ion mobility spectrometry method wherein ions are separated along a drift axis while providing a drift gas flow in a direction that is substantially neither in the direction of the drift axis nor opposite to the drift axis. Ion mobility spectrometer operation methods use a cross-directional gas flow in a drift tube and/or a segmented drift tube for pre-separation.

公开(公告)号：US09398926B2

公开(公告)日：2016-07-26

申请号：US12436010

申请日：2009-05-05

Applicant: Yu-Shi Weng ,  Yi-Hung Lin ,  Ya-Jen Yu ,  Shan-Chang Chueh ,  I-Ching Wu ,  Chris I. Huang

Inventor： Yu-Shi Weng ,  Yi-Hung Lin ,  Ya-Jen Yu ,  Shan-Chang Chueh ,  I-Ching Wu ,  Chris I. Huang

IPC: A61F2/44 ,  A61B17/70

CPC classification number: A61B17/7062 ,  A61B17/7065 ,  A61F2/44 ,  A61F2/4405

Abstract: An interspinous stabilization device includes: (1) a supporting member with a top surface and a bottom surface both being configured to engage spinous processes; (2) two side members connected to the supporting member; (3) a fastener attached to the side members; and optionally (4) two extendable arms each secured on one of the side members.

Abstract translation: 椎间稳定装置包括：（1）具有顶表面和底表面的支撑构件，其被构造成接合棘突; （2）连接到支撑构件的两个侧构件; （3）附接到侧构件的紧固件; 和可选地（4）两个可伸缩臂，每个固定在一个侧构件上。

公开(公告)号：US20150340214A1

公开(公告)日：2015-11-26

申请号：US14283499

申请日：2014-05-21

Applicant: Ching Wu

Inventor： Ching Wu

IPC: H01J49/00

CPC classification number: H01J49/049

Abstract: This invention describes a sample collection and desorption device and method that collects residues of explosives and other chemicals from a surface and then introduces them into a detector. The desorption method and device include introducing additional chemicals while heating up the sample collector, thus, the collected sample may be converted via a chemical reaction or a catalytic process. The detector can be an ion mobility spectrometer or mass spectrometer.

Abstract translation: 本发明描述了从表面收集炸药和其他化学物质的残留物并随后将其引入检测器的样品收集和解吸装置和方法。 解吸方法和装置包括在加热样品收集器的同时引入额外的化学品，因此，可以通过化学反应或催化过程转化收集的样品。 检测器可以是离子迁移谱仪或质谱仪。

公开(公告)号：US09177770B2

公开(公告)日：2015-11-03

申请号：US12763092

申请日：2010-04-19

Applicant: Mark A. Osgood ,  Ching Wu

Inventor： Mark A. Osgood ,  Ching Wu

IPC: H01J49/06 ,  G01N27/62 ,  C07B63/00

CPC classification number: H01J49/061 ,  C07B63/00 ,  G01N27/622 ,  Y10T29/49227

Abstract: The present invention generally relates to systems and methods for transmitting beams of charged particles, and in particular to such systems and methods that employ defecting at least one set of grid elements into the same plane to form an ion gate. In addition, an operation method of closing a gate involving alternating voltages on the adjacent gate wires is described.

Abstract translation: 本发明一般涉及用于传送带电粒子束的系统和方法，特别涉及这样的系统和方法，该系统和方法使用将至少一组栅格元件缺陷到同一平面中以形成离子门。 此外，描述了在相邻栅极线上闭合涉及交流电压的栅极的操作方法。

公开(公告)号：US09164077B2

公开(公告)日：2015-10-20

申请号：US13595648

申请日：2012-08-27

Applicant: Yi-Hsin Lin ,  Wei-Lin Chu ,  Li-Ching Wu

Inventor： Yi-Hsin Lin ,  Wei-Lin Chu ,  Li-Ching Wu

IPC: G01N33/00 ,  G01N33/49 ,  B01L3/00

CPC classification number: G01N33/49 ,  B01L3/502792 ,  B01L2400/0427

Abstract: The present invention discloses a biological detection device and a detecting method. The biological detection device comprises a substrate, an electric field unit, a liquid crystal/polymer composite film (LCPCF), a power supply, a processing unit, and an image sensor. Because of the electrically tunable orientations of the liquid crystal (LC) director anchored among the polymer grains, the wettability of the LCPCF changes with an applied electric field. As a result, we can manipulate a blood droplet on the LCPCF by a wettability gradient owing to the distribution of LC directors on the LCPCF. The motion states of the blood droplet can be related to the various qualities of the blood, and finally determines the health of the test sample. The change of contact angle of blood on LCPCF and the blood droplet motion on LCPCF indicate the concentration of TG and the concentration of HDL.

Abstract translation: 本发明公开了一种生物检测装置和检测方法。 生物检测装置包括基板，电场单元，液晶/聚合物复合膜（LCPCF），电源，处理单元和图像传感器。 由于在聚合物颗粒之间锚定的液晶（LC）导向器的电可调取向，所以LCPCF的润湿性随施加的电场而变化。 因此，由于LC导向器在LCPCF上的分布，我们可以通过润湿梯度来操纵LCPCF上的血滴。 血滴的运动状态可以与血液的各种质量相关，最终确定测试样品的健康状况。 血液对LCPCF的接触角变化和LCPCF上的血滴运动表明TG浓度和HDL浓度。