NOVEL THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF

    公开(公告)号:US20210171539A1

    公开(公告)日:2021-06-10

    申请号:US16768251

    申请日:2017-12-27

    Abstract: The present invention relates to a novel thieno[3,2-b]pyridine-5(4H)-one derivative compound, a preparation method thereof, and a use thereof. The novel thieno[3,2-b]pyridine-5(4H)-one derivative compound according to the present invention is synthesized via an aza-[3+3] cyclization addition reaction using BOP, wherein the compound is obtained by synthesizing a 4-arylthiophen-3-amine in which aryl groups such as 4-piperidyl-C6H4, 4-pyrrolidyl-C6H4, 4-MeOC6H4, 3,4,5-(MeO)3C6H4, C6H5, 4-C6H5C6H4, and 4-F3COC6H4 are introduced via a synthesis process by a bromination reaction, a hydrolysis reaction, a decarboxylation reaction, and a Suzuki coupling reaction of methyl 3-aminothiophene carboxylate, and by synthesizing 4-arylthiophen-3-amine and mono-methyl fumarate via a formal aza-[3+3] cyclization addition reaction using BOP and conjugation. Accordingly, novel thieno[3,2-b]pyridine-5(4H)-one derivative compounds according to the present invention have fluorescence properties with a wide range of emission wavelengths and thus may be utilized in various industrial fields such as physics, chemistry, and biomedical research.

    Container search system
    27.
    发明授权

    公开(公告)号:US10479621B2

    公开(公告)日:2019-11-19

    申请号:US15576754

    申请日:2017-02-28

    Abstract: The present invention relates to a container search system comprising: a radiation irradiation unit for irradiating radiation to a container to be inspected; a detection unit installed opposite to the radiation irradiation unit to detect radiation having passed through a container; a transfer cart for loading an automobile thereon, on which a container to be inspected is loaded, and travelling along a search path formed between the radiation irradiation unit and the detection unit; and a circulation orbit unit formed to allow the transfer cart to circulate along the search path, wherein a primary side of a linear induction motor for generating a moving magnetic field is formed on either side among the transfer cart and the search path and a secondary-side reaction plate for inducing a secondary eddy current due to the moving magnetic field and generating a linear driving force is formed on the other side thereof. The container search system can transfer a transfer cart according to a linear motor scheme in a radiation search section, and thus can obtain a radiation search image of high quality.

    High efficiency ocean thermal difference power generating system using liquid-vapor ejector and motive pump

    公开(公告)号:US09957955B2

    公开(公告)日:2018-05-01

    申请号:US14895280

    申请日:2015-03-05

    CPC classification number: F03G7/05 F01K5/00 F01K7/16 Y02E10/34

    Abstract: There is provided a high efficiency ocean thermal difference power generating system by using liquid-vapor ejector and motive pump comprising: an evaporator for changing transferred refrigerant liquid into refrigerant vapor with high temperature and high pressure by the thermal exchange with surface seawater; a vapor-liquid divider which is installed at the outlet part of the evaporator and divides the refrigerants to liquid-state refrigerant and vapor-state refrigerant respectively; a distributor which is installed at the inlet of the evaporator and distributes the refrigerants flowed into the evaporator to multi-paths; a turbine for generating electric power by using the high pressure refrigerant vapor transferred from the liquid-vapor divider or the evaporator; a motive pump for increasing the pressure of the refrigerant liquid distributed from the distributor or the liquid-vapor divider; a liquid-vapor ejector for mixing the low pressure refrigerant vapor which passed the turbine and the high pressure refrigerant liquid which passed a motive pump, thereby proceeding expansion and compression; a condenser for condensing the refrigerants which was mixed in the liquid-vapor ejector by the thermal exchange with deep seawater; and a refrigerant circulation pump for increasing the pressure of the refrigerants which was condensed in the condenser up to the evaporation pressure and for circulating.

    Suction foundation having enhanced self-weight penetration and construction method thereof
    29.
    发明授权
    Suction foundation having enhanced self-weight penetration and construction method thereof 有权
    吸力基体具有增强的自重穿透力及其施工方法

    公开(公告)号:US09574316B2

    公开(公告)日:2017-02-21

    申请号:US15081094

    申请日:2016-03-25

    Abstract: The present relates to a suction foundation in which is penetrated into the seabed by a vacuum pressure of a suction pump, thereby providing a desired foundation support force. The suction foundation includes a hollow caisson having an opening at a lower end thereof, where the suction pump is connected to the hollow caisson and the suction pump allows the hollow caisson to penetrate into the seabed while discharging a fluid in the hollow caisson to an outside thereof by using the vacuum pressure of the suction pump, a lower skirt provided along a circumference of the opening of the hollow caisson and formed into a wave shape having a series of teeth, and having wedge-shaped cross-sections, and a stiffener increasing rigidity of the lower skirt by increasing thickness of a predetermined portion of the lower skirt.

    Abstract translation: 本发明涉及一种吸入基座,其中通过抽吸泵的真空压力将其吸入海底,从而提供所需的基础支撑力。 抽吸基座包括在其下端具有开口的中空沉箱,其中抽吸泵连接到中空沉箱,并且抽吸泵允许中空沉箱渗透到海床中,同时将中空沉箱中的流体排放到外部 通过使用抽吸泵的真空压力,沿着中空沉箱的开口的圆周设置的下部裙部,并形成为具有一系列齿的波形,并具有楔形横截面,并且加强件增加 通过增加下裙部的预定部分的厚度来确定下裙部的刚性。

    Cold-adapted protease derived from Pseudoalteromonas arctica PAMC 21717 and uses thereof
    30.
    发明授权
    Cold-adapted protease derived from Pseudoalteromonas arctica PAMC 21717 and uses thereof 有权
    衍生自Pseudoalteromonas arctica PAMC 21717的冷适应蛋白酶及其用途

    公开(公告)号:US09574185B2

    公开(公告)日:2017-02-21

    申请号:US14583557

    申请日:2014-12-26

    Abstract: A cold-adapted protease derived from Pseudoalteromonas arctica PAMC 21717 or a recombinant cold-adapted protease obtained by expressing a gene encoding the cold-adapted protease in E. coli is described, and more particularly, a crystal of a protease exhibiting activity at low temperatures, a method for crystallizing the protease, a method for preparing the protease, a recombinant microorganism that expresses the protease, a method for preparing the recombinant microorganism, a method for preparing the recombinant protease and the use of the cold-adapted protease. The cold-adapted protease exhibits high activity at low temperatures, and securely maintains its enzymatic activity even in the presence of high pH, various metal ions and surfactants. Thus, it is useful in various industrial applications.

    Abstract translation: 描述了衍生自Pseudoalteromonas arctica PAMC 21717的冷适应蛋白酶或通过在大肠杆菌中表达编码冷适应蛋白酶的基因而获得的重组冷适应蛋白酶,更具体地,描述了在低温下表现出活性的蛋白酶的晶体 蛋白酶结晶方法,蛋白酶的制备方法,表达蛋白酶的重组微生物,重组微生物的制备方法,重组蛋白酶的制备方法及冷适应蛋白酶的使用。 冷适应蛋白酶在低温下表现出高活性,即使在高pH,各种金属离子和表面活性剂的存在下也可以保持其酶活性。 因此,它在各种工业应用中是有用的。

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