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    MOVING IMAGE ENCODING AND DECODING SYSTEM
    23.
    发明申请
    MOVING IMAGE ENCODING AND DECODING SYSTEM 有权
    移动图像编码和解码系统

    公开(公告)号：US20110222601A1

    公开(公告)日：2011-09-15

    申请号：US13051768

    申请日：2011-03-18

    Applicant: Yoshinori Suzuki ,  Choong Seng Boon ,  Jens-Rainer Ohm ,  Mathias Wien ,  Aleksandar Stojanovic ,  Thiow Keng Tan

    Inventor： Yoshinori Suzuki ,  Choong Seng Boon ,  Jens-Rainer Ohm ,  Mathias Wien ,  Aleksandar Stojanovic ,  Thiow Keng Tan

    IPC: H04N7/26

    CPC classification number: H04N19/573 ,  H04N19/51 ,  H04N19/593

    Abstract: A moving image encoding and decoding system reduces compressed moving picture data amounts by producing a prediction signal suitable for moving pictures including dynamic textures. The system includes a moving picture encoding device 1 that includes a block divider 102 receiving a target pixel signal, a prediction signal generator 103 producing a prediction signal, a subtractor 105 producing a differential signal, and a transformer 106 and quantizer 107 producing an encoded differential signal. The encoding device 1 also includes an inverse quantizer 108 and inverse transformer 109 producing a decoded differential signal, an adder 110 producing a reproduction signal, a frame memory 104 storing the reproduction signal as a reference image, and a reference image generator 113. The reference image generator 113 may obtain an observation matrix C by using a pre-existing reference image. The encoding system 1 produces a new reference image y″t+5 based on the observation matrix C and a state vector xt+5, and stores the new reference image in the frame memory 104. The prediction signal generator 103 produces the prediction signal by using at least the new reference image y″t+5.

    Abstract translation: 运动图像编码和解码系统通过产生适合于包括动态纹理的运动图像的预测信号来减少压缩的运动图像数据量。 该系统包括运动图像编码装置1，其包括接收目标像素信号的块分割器102，产生预测信号的预测信号发生器103，产生差分信号的减法器105以及产生编码差分的变换器106和量化器107 信号。 编码装置1还包括产生解码差分信号的逆量化器108和逆变换器109，产生再现信号的加法器110，存储再现信号作为参考图像的帧存储器104和参考图像生成器113。 图像生成器113可以通过使用预先存在的参考图像来获得观察矩阵C. 编码系统1基于观察矩阵C和状态向量xt + 5产生新的参考图像y“t + 5，并将新的参考图像存储在帧存储器104中。预测信号发生器103通过 至少使用新的参考图像y“t + 5。

    5-amino 4-hydroxy-7-(1H-indolmethyl)-8-methylnonamide derivatives as renin inhibitors for the treatment of hypertension
    25.
    发明授权
    5-amino 4-hydroxy-7-(1H-indolmethyl)-8-methylnonamide derivatives as renin inhibitors for the treatment of hypertension 失效
    5-氨基-4-羟基-7-（1H-吲哚甲基）-8-甲基壬酰胺衍生物作为治疗高血压的肾素抑制剂

    公开(公告)号：US07851634B2

    公开(公告)日：2010-12-14

    申请号：US10593460

    申请日：2005-03-17

    Applicant: Peter Herold ,  Stefan Stutz ,  Robert Mah ,  Vincenzo Tschinke ,  Aleksandar Stojanovic ,  Nathalie Jotterand ,  Michael Quirmbach ,  Dirk Behnke ,  Christiane Marti

    Inventor： Peter Herold ,  Stefan Stutz ,  Robert Mah ,  Vincenzo Tschinke ,  Aleksandar Stojanovic ,  Nathalie Jotterand ,  Michael Quirmbach ,  Dirk Behnke ,  Christiane Marti

    IPC: C07D405/02 ,  A61K31/44

    CPC classification number: C07C237/06 ,  C07C237/22 ,  C07D209/12 ,  C07D231/56 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  C07D417/12

    Abstract: The application relates to novel alkanamides of the general formula (I) where X is —CH2— or >CH—OH; (A) R1 is e.g. an optionally substituted heterocyclyl radical or an optionally substituted polycyclic, unsaturated hydrocarbon radical where X is hydroxymethylene; R2 is C1-C6-alkyl or C3-C6-cydoalkyl; R3 are each independently H, C1-C6-alkyl, C1-6-alkoxycarbonyl or C1-C6-alkanoyl; R4 is C1-C6-alkyl, C3-C6-cycloalkyl, C2-C6-alkenyl or unsubstituted or substituted arylC1-C6-alkyl; R5 is C1-C6-alkyl, C1-C6-hydroxyalkyl, C1-C6-alkoxy-C1-C6-alkyl, C1-C6-alkanoyloxy C1-C6-alkyl, C1-C6-aminoalkyl, C1-C6-alkylamino-C1-C6-alkyl, C1-C6-dialkylamino-C1-C6-alkyl, C1-C6-alkanoylamido-C1-C6-alkyl, HO(O)C—C1-C6-alkyl, C1-C6-alkyl-O—(O)C—C1-C6-alkyl, H2N—C(O)—C1-C6-alkyl, C1-C6-alkyl-HN—C(O)—C1-C6-alkyl, (C1,-C6-alkyl)2N—C(O)—C1-C6-alkyl, C2-C8-alkenyl, C2-C8-alkynyl, cyano-C1-C6-alkyl, halo-C1-C6-alkyl, optionally substituted aryl-Co-C6-alkyl, optionally substituted C3-C8-cycloalkyl-Co-C6-alkyl or optionally substituted heterocydyl-Co-C6-alkyl; to a process for their preparation and to the use of these compounds as medicines, especially as renin inhibitors for the treatment of hypertension.

    Abstract translation: 本申请涉及通式（I）的新型烷酰胺，其中X为-CH 2 - 或> CH-OH; （A）R1是例如 任选取代的杂环基或任选取代的多环不饱和烃基，其中X是羟基亚甲基; R2是C1-C6-烷基或C3-C6-环烷基; R 3各自独立地为H，C 1 -C 6 - 烷基，C 1-6 - 烷氧基羰基或C 1 -C 6 - 烷酰基; R4是C1-C6-烷基，C3-C6-环烷基，C2-C6-烯基或未取代或取代的芳基C1-C6-烷基; R5是C1-C6-烷基，C1-C6-羟基烷基，C1-C6-烷氧基-C1-C6-烷基，C1-C6-烷酰氧基C1-C6-烷基，C1-C6-氨基烷基，C1-C6烷基氨基-C1 C 1 -C 6 - 烷基，C 1 -C 6 - 二烷基氨基-C 1 -C 6 - 烷基，C 1 -C 6 - 烷酰基氨基-C 1 -C 6烷基，HO（O）C 1 -C 6 - 烷基，C 1 -C 6烷基-O-（ O）-C 1 -C 6烷基，H 2 N-C（O）-C 1 -C 6 - 烷基，C 1 -C 6烷基-NH-C（O）-C 1 -C 6 - 烷基，（C 1 -C 6 - 烷基） C 1 -C 6 - 烷基，C 2 -C 8 - 烯基，C 2 -C 8炔基，氰基-C 1 -C 6烷基，卤代-C 1 -C 6烷基，任选取代的芳基-C 0 -C 6 - 烷基 ，任选取代的C 3 -C 8 - 环烷基-C 0 -C 6 - 烷基或任选取代的杂环-Co-C 6 - 烷基; 其制备方法和这些化合物作为药物的使用，特别是用作治疗高血压的肾素抑制剂。

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