公开(公告)号：US08607218B2

公开(公告)日：2013-12-10

申请号：US13260219

申请日：2010-02-25

申请人： Giovanni Motta ,  Ashish Varma ,  Brian O'Neill ,  LaShawn McGhee

发明人： Giovanni Motta ,  Ashish Varma ,  Brian O'Neill ,  LaShawn McGhee

IPC分类号： G06F9/44

CPC分类号： G06F8/65

摘要： A method of updating computer software includes identifying an orphaned computer file in a second version of computer software, the orphaned computer file having a name that does not correspond to any name of a computer file in a first version of computer software and computing symmetric divergence between the orphaned computer file and each computer file in the first version of computer software. The method also includes choosing a file from the computer files in the first version of computer software that yields a minimum value of symmetric divergence between the file and the orphaned computer file and using the file as a reference file for compressing the orphaned computer file.

摘要翻译： 更新计算机软件的方法包括在计算机软件的第二版本中识别孤立的计算机文件，所述孤立的计算机文件具有与计算机软件的第一版本中的计算机文件的任何名称不对应的名称，并且计算在第 孤立的计算机文件和计算机软件的第一个版本中的每个计算机文件。 该方法还包括从计算机软件的第一版本中的计算机文件中选择一个文件，该文件产生文件和孤立计算机文件之间的对称分歧的最小值，并使用该文件作为压缩孤立计算机文件的参考文件。

公开(公告)号：US20120023489A1

公开(公告)日：2012-01-26

申请号：US13260219

申请日：2010-02-25

申请人： Giovanni Motta ,  Ashish Varma ,  Brian O'Neill ,  LaShawn McGhee

发明人： Giovanni Motta ,  Ashish Varma ,  Brian O'Neill ,  LaShawn McGhee

IPC分类号： G06F9/44

CPC分类号： G06F8/65

摘要： A method of updating computer software includes identifying an orphaned computer file in a second version of computer software, the orphaned computer file having a name that does not correspond to any name of a computer file in a first version of computer software and computing symmetric divergence between the orphaned computer file and each computer file in the first version of computer software. The method also includes choosing a file from the computer files in the first version of computer software that yields a minimum value of symmetric divergence between the file and the orphaned computer file and using the file as a reference file for compressing the orphaned computer file.

摘要翻译： 更新计算机软件的方法包括在计算机软件的第二版本中识别孤立的计算机文件，所述孤立的计算机文件具有与计算机软件的第一版本中的计算机文件的任何名称不对应的名称，并且计算在第 孤立的计算机文件和计算机软件的第一个版本中的每个计算机文件。 该方法还包括从计算机软件的第一版本中的计算机文件中选择一个文件，该文件产生文件和孤立计算机文件之间的对称分歧的最小值，并使用该文件作为压缩孤立计算机文件的参考文件。

公开(公告)号：US20100010393A1

公开(公告)日：2010-01-14

申请号：US12169448

申请日：2008-07-08

申请人： Niall Duffy ,  Richard Houben ,  Ashish Varma ,  Sean Whelan

发明人： Niall Duffy ,  Richard Houben ,  Ashish Varma ,  Sean Whelan

IPC分类号： A61N7/00

CPC分类号： A61N7/02 ,  A61B17/22004 ,  A61B2017/00106 ,  A61B2017/00703

摘要： An apparatus for treating an occlusion in a vessel inside of a patient. The apparatus includes an external high intensity focused ultrasound transducer configured to be positioned outside of the vessel and to emit ultrasonic waves of energy to the occlusion and to detect ultrasonic waves of energy, an internal ultrasound transducer configured to be positioned inside of the vessel at a position adjacent to or inside the occlusion and to emit ultrasonic waves of energy for detection by the external high intensity focused ultrasound transducer, and a controller configured to control the ultrasonic waves of energy emitted by the external high intensity focused ultrasound transducer based on an electrocardiogram of the patient.

摘要翻译： 一种用于治疗患者体内血管闭塞的装置。 该装置包括外部高强度聚焦超声波换能器，其被配置为位于血管外部并且向闭塞发射能量的超声波并检测能量的超声波;内部超声波换能器被配置为定位在血管内部 位于与闭塞相邻或内部的位置，并且发射超声波能量以供外部高强度聚焦超声波换能器检测;以及控制器，被配置为基于外部高强度聚焦超声波换能器的心电图 患者。

公开(公告)号：US20090264771A1

公开(公告)日：2009-10-22

申请号：US12107536

申请日：2008-04-22

申请人： Richard HOUBEN ,  Sean WHELAN ,  Niall DUFFY ,  Ashish VARMA

发明人： Richard HOUBEN ,  Sean WHELAN ,  Niall DUFFY ,  Ashish VARMA

IPC分类号： A61B8/00

CPC分类号： A61B8/4488 ,  A61B5/02007 ,  A61B8/0833 ,  A61B8/12 ,  A61B8/4483

摘要： A probe for detecting at least one property of a chronic total occlusion in a lumen. The probe includes an elongated member having a distal end configured to be inserted into the lumen, and an ultrasound transducer mounted at the distal end of the elongated member. The ultrasound transducer is configured to emit an ultrasonic signal and to receive a reflected signal from the chronic total occlusion. The probe also includes a processor configured to receive the reflected signal from the ultrasound transducer and convert the reflected signal to at least one property of the chronic total occlusion.

摘要翻译： 用于检测管腔中慢性完全闭塞的至少一种性质的探针。 探针包括细长构件，其具有构造成插入到内腔中的远端，以及安装在细长构件的远端处的超声换能器。 超声换能器被配置为发射超声波信号并且接收来自慢性完全闭塞的反射信号。 探针还包括处理器，其被配置为从超声换能器接收反射信号并将反射的信号转换成慢性完全闭塞的至少一个特性。

公开(公告)号：US20060175739A1

公开(公告)日：2006-08-10

申请号：US11053359

申请日：2005-02-08

申请人： Gerard Hession ,  Donagh O'Shaughnessy ,  Gerry Clarke ,  Seamus Ledwith ,  Michael Cummins ,  Noel Quinn ,  Ashish Varma

发明人： Gerard Hession ,  Donagh O'Shaughnessy ,  Gerry Clarke ,  Seamus Ledwith ,  Michael Cummins ,  Noel Quinn ,  Ashish Varma

IPC分类号： A21C11/00 ,  B29D22/00

CPC分类号： B29C33/3828 ,  A61M25/1029 ,  B29C33/40 ,  B29C49/14 ,  B29C49/48 ,  B29C2033/0005 ,  B29C2049/0089 ,  B29K2105/258 ,  B29K2905/10 ,  B29K2905/12 ,  B29K2909/02 ,  B29K2909/08 ,  B29K2995/0026 ,  B29K2995/0029 ,  B29L2031/7542

摘要： A mold for forming a balloon of a balloon catheter including a body portion defining a body region of a mold cavity and distal and proximal end caps defining tapering regions and neck regions of the mold cavity. During the molding process, the mold cavity is visible from an exterior surface of the body portion, which is transparent or translucent. The distal and proximal end caps are metal and can be precision machined in the tapering and neck regions of the mold cavity in order to achieve more accurate molded balloon dimensions. Also disclosed is a method for making a balloon of a balloon catheter using the mold and a balloon made therefrom.

摘要翻译： 一种用于形成球囊导管气囊的模具，包括限定模具腔的主体区域的主体部分和限定模腔的锥形区域和颈部区域的远端和近端帽。 在模制过程中，模腔从身体部分的外表面是可见的，其为透明或半透明的。 远端和近端帽是金属的，并且可以在模腔的锥形和颈部区域中精密加工，以便实现更精确的模制气囊尺寸。 还公开了一种使用模具制造球囊导管球囊的方法和由其制成的气囊。

公开(公告)号：US20050098914A1

公开(公告)日：2005-05-12

申请号：US10920458

申请日：2004-08-18

申请人： Ashish Varma ,  Kimberly Chaffin ,  Frank Bates ,  Marc Hillmyer ,  Lisa Lim ,  Tamotsu Harada

发明人： Ashish Varma ,  Kimberly Chaffin ,  Frank Bates ,  Marc Hillmyer ,  Lisa Lim ,  Tamotsu Harada

IPC分类号： A61L29/00 ,  A61L29/04 ,  A61M25/00 ,  B29C47/00 ,  B29C55/04 ,  B29C55/12 ,  B29C71/00 ,  B65D1/00

CPC分类号： A61L29/04 ,  A61L29/049 ,  C08L53/00 ,  Y10T428/1352

摘要： A self-wrapping dilatation balloon comprising a multiblock copolymer having high elasticity and elastic recovery from nominal strains greater than about 30% is described. Also described herein, is a polymeric extrudate for making a dilatation balloon comprising a multiblock copolymer having tensile strength in the range of about 50 MPa to about 450 MPa, strain at break in the range of about 50% to about 600% and substantially complete elastic recovery from nominal strains of at least about 30%. The extrudate has phase-separated microdomains that are macroscopically aligned in parallel, perpendicular, transverse or a combination thereof. Also described herein is a process for producing a polymeric extrudate for use as a dilatation balloon. The process comprises extruding a multiblock copolymer mixture or composition to form an extrudate. The extruding is done such that the extrudate has phase-separated microdomains that are macroscopically aligned in parallel, perpendicular, transverse or a combination thereof. After extrusion, the process optionally comprises the steps of drawing and coagulating the extrudate.

摘要翻译： 描述了包含具有高于约30％的标称应变的高弹性和弹性恢复的多嵌段共聚物的自包裹膨胀气球。 本文还描述了一种用于制造膨胀气囊的聚合物挤出物，其包含具有约50MPa至约450MPa范围内的拉伸强度，约50％至约600％范围内的拉伸应变和基本上完全弹性的多嵌段共聚物 从名义菌株中恢复至少约30％。 挤出物具有相分离的微区域，它们在宏观上对齐，平行，垂直，横向或其组合。 本文还描述了用于生产用作膨胀气球的聚合物挤出物的方法。 该方法包括挤出多嵌段共聚物混合物或组合物以形成挤出物。 进行挤出使得挤出物具有相互分离的微区域，其宏观地对准在平行，垂直，横向或其组合。 挤出后，该方法任选地包括拉伸和凝结挤出物的步骤。