Method of preparing sodium salts of imidazoledicarboxylic acid
substituted cephalosporin derivatives
    21.
    发明授权
    Method of preparing sodium salts of imidazoledicarboxylic acid substituted cephalosporin derivatives 失效
    制备咪唑二羧酸取代头孢菌素衍生物的钠盐的方法

    公开(公告)号:US4423215A

    公开(公告)日:1983-12-27

    申请号:US353809

    申请日:1982-03-02

    CPC分类号: C07D501/46

    摘要: A method of preparing sodium salts of an imidazoledicarboxylic acid derivative of a substituted cephalosporin represented by the general formula of ##STR1## where X is a radical selected from the group consisting of hydrogen, halogen, hydroxyl, alkyl, aryl, aralkyl, alkoxy, aryloxy, aralkyloxy, mercapto, alkylthio, arylthio, aralkylthio, alkylsulfonyl, arylsulfonyl, aralkylsulfonyl, alkylsulfinyl, arylsulfinyl, aralkylsulfinyl, amino, mono- or dialkylamino, mono- or diarylamino, mono- or diaralkylamino, acylamino, sulfonic acid, nitro or heterocyclic group;and where R is a radical selected from hydrogen, an organic radical such as alkyl, aryl or aralkyl or a heterocyclic group, said organic radical and heterocyclic group being optionally substituted;said method comprising reacting a compound represented by the following formula: ##STR2## with 4-pyridineethanesulfonic acid in an aqueous solution of sodium iodide and subsequently recovering the salt.The compounds are useful in the treatment of bacterial infections, particularly Pseudomonas aeruginosa, in man and other animals.

    摘要翻译: 一种制备由通式(I)< IMAGE>表示的取代头孢菌素的咪唑二羧酸衍生物的钠盐的方法,其中X是选自氢,卤素,羟基,烷基,芳基 芳烷氧基,烷氧基,芳氧基,芳烷硫基,芳烷硫基,烷基磺酰基,芳基磺酰基,芳烷基磺酰基,烷基亚磺酰基,芳基亚磺酰基,芳烷基亚磺酰基,氨基,一烷基氨基或二芳基氨基,单或二芳基氨基, ,硝基或杂环基; 并且其中R是选自氢,有机基团如烷基,芳基或芳烷基或杂环基的基团,所述有机基团和杂环基团任选被取代; 所述方法包括将由下式表示的化合物与4-吡啶乙磺酸在碘化钠水溶液中反应,随后回收盐。 这些化合物可用于治疗人和其他动物中细菌感染,特别是铜绿假单胞菌(Pseudomonas aeruginosa)。

    Surface light emitting device
    29.
    发明授权
    Surface light emitting device 失效
    表面发光装置

    公开(公告)号:US06601962B1

    公开(公告)日:2003-08-05

    申请号:US09567428

    申请日:2000-05-10

    IPC分类号: F21V800

    CPC分类号: G02B6/0016 G02B6/002

    摘要: An surface light emitting device that is capable of emitting light of high luminance with higher uniformity is disclosed. The surface light emitting device comprising; a light guide plate, a reflector on the under surface of the light guide plate and, an LED light source having at least one LED element and provided so that a light emitted by the LED element is incident on at least one end face of the light guide plate, wherein the light guide plate has a light diffusing portion on the one end face so that a light emitted from the LED light source enters the light guide plate while being diffused therein, and the light diffusing portion has the top end being space from the top surface.

    摘要翻译: 公开了能够以更高的均匀性发射高亮度的光的面发光器件。 导光板,导光板的下表面上的反射器和具有至少一个LED元件的LED光源,并且被设置为使得由LED元件发射的光入射到光的至少一个端面上 导光板,其中所述导光板在所述一个端面上具有光漫射部分,使得从所述LED光源发射的光在其中扩散时进入所述导光板,并且所述光扩散部分的顶端与 顶面。