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32 条记录 (耗时 0.033 秒)

    Configuring stimulation therapy using stimulation intensity
    21.
    发明授权
    Configuring stimulation therapy using stimulation intensity 有权
    使用刺激强度配置刺激治疗

    公开(公告)号：US08447413B2

    公开(公告)日：2013-05-21

    申请号：US12111822

    申请日：2008-04-29

    申请人： Richard T. Stone ,  Steven M. Goetz ,  Gregory F. Molnar ,  Gabriela C. Miyazawa ,  Martin T. Gerber

    发明人： Richard T. Stone ,  Steven M. Goetz ,  Gregory F. Molnar ,  Gabriela C. Miyazawa ,  Martin T. Gerber

    IPC分类号： A61N1/00

    CPC分类号： A61N1/0534 ,  A61N1/0551 ,  A61N1/36082 ,  A61N1/37247

    摘要： Techniques for configuring electrical stimulation therapy utilizing one or more stimulation intensity values are described. In one example, a method includes receiving a stimulation intensity value that corresponds to an equal intensity function; determining a pulse width value and a pulse amplitude value based on the equal intensity function; and controlling delivery of electrical stimulation pulses with the determined pulse width value and amplitude value to a patient. A stimulation intensity value may correspond to a plurality of paired pulse width and amplitude values having substantially the same intensity. For example, the plurality of paired pulse width and amplitude values may activate a substantially equal volume of tissue when a stimulation pulse with the paired values is delivered.

    摘要翻译： 描述了利用一个或多个刺激强度值来配置电刺激治疗的技术。 在一个示例中，一种方法包括接收对应于等强度函数的刺激强度值; 基于等强度函数确定脉冲宽度值和脉冲振幅值; 并且以确定的脉冲宽度值和振幅值来控制对电刺激脉冲的传递给患者。 刺激强度值可以对应于具有基本上相同强度的多个成对的脉冲宽度和幅度值。 例如，当递送具有成对值的刺激脉冲时，多个成对的脉冲宽度和振幅值可以激活基本上相等体积的组织。

    Medical device configuration based on sensed brain signals
    24.
    发明授权
    Medical device configuration based on sensed brain signals 有权
    基于感觉到的大脑信号的医疗设备配置

    公开(公告)号：US07983757B2

    公开(公告)日：2011-07-19

    申请号：US12133999

    申请日：2008-06-05

    申请人： Gabriela C. Miyazawa ,  Gregory F. Molnar

    发明人： Gabriela C. Miyazawa ,  Gregory F. Molnar

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36071 ,  A61B5/048 ,  A61B5/7257

    摘要： The invention is directed to techniques and systems in which external brain monitoring is used to facilitate implantation and configuration of an implantable medical device. The techniques may create an open loop or closed loop system in which brain signals quantify the efficacy of electrical logical stimulation (or drug therapy via an implantable drug pump) at locations outside of the brain. The techniques may be used to improve placement of leads and electrodes during an implantation procedure, and/or to select or adjust stimulation parameters either during the implantation procedure or possibly following implantation of an implantable medical device. The described techniques have applications for the alleviation of pain, but may find other applications where EEG signals can quantify the efficacy of treatment via an implantable medical device.

    摘要翻译： 本发明涉及使用外部脑部监测来促进可植入医疗装置的植入和构造的技术和系统。 这些技术可以产生开环或闭环系统，其中脑信号定量在脑外部位置的电逻辑刺激（或通过可植入药物泵的药物治疗）的功效。 这些技术可以用于在植入过程期间改善引线和电极的放置，和/或在植入过程期间或可能在植入可植入医疗器械之后选择或调整刺激参数。 所描述的技术具有减轻疼痛的应用，但是可以找到其他应用，其中EEG信号可以通过可植入医疗装置量化治疗的功效。

    Implantable medical lead with multiple electrode configurations
    25.
    发明授权
    Implantable medical lead with multiple electrode configurations 有权
    具有多种电极配置的植入式医用导线

    公开(公告)号：US07668601B2

    公开(公告)日：2010-02-23

    申请号：US11740643

    申请日：2007-04-26

    申请人： Michael T. Hegland ,  James M. Olsen ,  Gabriela C. Miyazawa ,  Richard T. Stone

    发明人： Michael T. Hegland ,  James M. Olsen ,  Gabriela C. Miyazawa ,  Richard T. Stone

    IPC分类号： A61N1/04

    CPC分类号： A61N1/0534 ,  A61N1/36082

    摘要： Medical leads having at least one segmented row of electrodes, as well as at least one ring electrode that extends substantially completely around the periphery of the lead, are described. The electrodes in a segmented row extend around only a portion of the periphery of the lead, rather than substantially around the entire periphery. The electrodes in a segmented row may be distributed at respective locations around the periphery of the lead and separated by insulating material. The ring electrodes and segmented rows are located at respective axial positions. For example, in some embodiments, a plurality of segmented rows, such as two rows having three electrodes each, are located between two ring electrodes. Such a lead may, for example, provide a variety of stimulation modalities because of localized stimulation capabilities.

    摘要翻译： 描述了具有至少一个分段的电极列的医疗引线以及基本上完全围绕引线周边延伸的至少一个环形电极。 分段行中的电极仅围绕引线周边的一部分延伸，而不是基本上围绕整个周边延伸。 分段行中的电极可以分布在引线的周围的相应位置处并被绝缘材料隔开。 环形电极和分段行位于相应的轴向位置。 例如，在一些实施例中，多个分段行（例如具有三个电极的两行）分布在两个环形电极之间。 例如，这样的引线可以由于局部刺激能力而提供各种刺激模式。

    CONFIGURING STIMULATION THERAPY USING STIMULATION INTENSITY
    26.
    发明申请
    CONFIGURING STIMULATION THERAPY USING STIMULATION INTENSITY 有权
    使用刺激强度配置刺激治疗

    公开(公告)号：US20090270947A1

    公开(公告)日：2009-10-29

    申请号：US12111822

    申请日：2008-04-29

    申请人： Richard T. Stone ,  Steven M. Goetz ,  Gregory F. Molnar ,  Gabriela C. Miyazawa ,  Martin T. Gerber

    发明人： Richard T. Stone ,  Steven M. Goetz ,  Gregory F. Molnar ,  Gabriela C. Miyazawa ,  Martin T. Gerber

    IPC分类号： A61N1/08

    CPC分类号： A61N1/0534 ,  A61N1/0551 ,  A61N1/36082 ,  A61N1/37247

    摘要： Techniques for configuring electrical stimulation therapy utilizing one or more stimulation intensity values are described. In one example, a method includes receiving a stimulation intensity value that corresponds to an equal intensity function; determining a pulse width value and a pulse amplitude value based on the equal intensity function; and controlling delivery of electrical stimulation pulses with the determined pulse width value and amplitude value to a patient. A stimulation intensity value may correspond to a plurality of paired pulse width and amplitude values having substantially the same intensity. For example, the plurality of paired pulse width and amplitude values may activate a substantially equal volume of tissue when a stimulation pulse with the paired values is delivered.

    摘要翻译： 描述了利用一个或多个刺激强度值来配置电刺激治疗的技术。 在一个示例中，一种方法包括接收对应于等强度函数的刺激强度值; 基于等强度函数确定脉冲宽度值和脉冲振幅值; 并且以确定的脉冲宽度值和振幅值来控制对电刺激脉冲的传递给患者。 刺激强度值可以对应于具有基本上相同强度的多个成对的脉冲宽度和幅度值。 例如，当递送具有成对值的刺激脉冲时，多个成对的脉冲宽度和振幅值可以激活基本上相等体积的组织。

    ELECTRODE CONFIGURATIONS FOR DIRECTIONAL LEADS
    27.
    发明申请
    ELECTRODE CONFIGURATIONS FOR DIRECTIONAL LEADS 审中-公开
    用于方向导线的电极配置

    公开(公告)号：US20090054947A1

    公开(公告)日：2009-02-26

    申请号：US12195277

    申请日：2008-08-20

    申请人： David Wayne Bourn ,  John L. Sommer ,  Mark T. Marshall ,  Michael D. Eggen ,  Gabriela C. Miyazawa

    发明人： David Wayne Bourn ,  John L. Sommer ,  Mark T. Marshall ,  Michael D. Eggen ,  Gabriela C. Miyazawa

    IPC分类号： A61N1/362 ,  A61N1/05

    CPC分类号： A61N1/368 ,  A61N1/0534 ,  A61N1/0551 ,  A61N1/056 ,  A61N1/36114 ,  A61N1/3684 ,  A61N2001/0585

    摘要： A system includes an implantable electrical stimulation lead configured for intravenous introduction into a vessel proximate to a heart and an electrical stimulator. The lead comprises a lead body and at least three electrode segments. The electrical stimulator is coupled to the electrode segments and configures a first of the electrode segments as a first anode, a second of the electrode segments as a cathode, and a third of the electrode segments as a second anode, and delivers electrical stimulation to the heart via the cathode and first and second anodes. Additional techniques for delivering electrical stimulation include using multiple electrode segments as cathodes and electrically isolating other electrode segments. Other examples are directed to techniques for directing electrical therapy to a vagus nerve of a patient.

    摘要翻译： 系统包括可植入的电刺激引线，其被配置为静脉内引入靠近心脏的血管和电刺激器。 引线包括引线体和至少三个电极段。 电刺激器耦合到电极段并且将第一电极段配置为第一阳极，将第二电极段作为阴极，将第三电极段作为第二阳极，并将电刺激传递到 心脏通过阴极和第一和第二阳极。 用于递送电刺激的附加技术包括使用多个电极段作为阴极并电隔离其它电极段。 其他实例涉及将电疗法引导到患者的迷走神经的技术。

    EVALUATING THERAPEUTIC STIMULATION ELECTRODE CONFIGURATIONS BASED ON PHYSIOLOGICAL RESPONSES
    28.
    发明申请
    EVALUATING THERAPEUTIC STIMULATION ELECTRODE CONFIGURATIONS BASED ON PHYSIOLOGICAL RESPONSES 有权
    基于生理反应评估治疗性刺激电极配置

    公开(公告)号：US20090054946A1

    公开(公告)日：2009-02-26

    申请号：US12195317

    申请日：2008-08-20

    申请人： John L. Sommer ,  David Wayne Bourn ,  Mark T. Marshall ,  Michael D. Eggen ,  Gabriela C. Miyazawa

    发明人： John L. Sommer ,  David Wayne Bourn ,  Mark T. Marshall ,  Michael D. Eggen ,  Gabriela C. Miyazawa

    IPC分类号： A61N1/08

    CPC分类号： A61N1/36514 ,  A61N1/056 ,  A61N1/36114 ,  A61N1/36185 ,  A61N1/3684 ,  A61N1/3686 ,  A61N2001/0585

    摘要： A medical system comprises a plurality of electrodes; at least one sensor configured to output at least one signal based on at least one physiological parameter of a patient; and a processor. The processor is configured to control delivery of stimulation to the patient using a plurality of electrode configurations. Each of the electrode configurations comprises at least one of the plurality of electrodes. For each of the electrode configurations, the processor is configured to determine a first response of target tissue to the stimulation based on the signals, and a second response of non-target tissue to the stimulation based on the signals. The processor is also configured to select at least one of the electrode configurations for delivery of stimulation to the patient based on the first and second responses for the electrode configurations. As examples, the target tissue may be a left ventricle or vagus nerve.

    摘要翻译： 医疗系统包括多个电极; 至少一个传感器被配置为基于患者的至少一个生理参数输出至少一个信号; 和处理器。 处理器被配置为使用多个电极配置来控制对患者的刺激递送。 每个电极配置包括多个电极中的至少一个。 对于每个电极配置，处理器被配置为基于信号来确定目标组织对刺激的第一响应，以及基于该信号来确定非目标组织对刺激的第二响应。 处理器还被配置为基于电极配置的第一和第二响应来选择用于将刺激递送到患者的电极配置中的至少一个。 作为示例，靶组织可以是左心室或迷走神经。

    User interface with toolbar for programming electrical stimulation therapy
    30.
    发明申请
    User interface with toolbar for programming electrical stimulation therapy 有权
    用户界面，用于编程电刺激治疗工具栏

    公开(公告)号：US20080163097A1

    公开(公告)日：2008-07-03

    申请号：US11999726

    申请日：2007-12-06

    申请人： Steven M. Goetz ,  Jeffrey T. Keacher ,  Rajeev Sahasrabudhe ,  Wende L. Dewing ,  Jon P. Davis ,  John Rondoni ,  Gabriela C. Miyazawa ,  Gary W. King

    发明人： Steven M. Goetz ,  Jeffrey T. Keacher ,  Rajeev Sahasrabudhe ,  Wende L. Dewing ,  Jon P. Davis ,  John Rondoni ,  Gabriela C. Miyazawa ,  Gary W. King

    IPC分类号： G06F3/048

    CPC分类号： A61N1/37247 ,  A61N1/36185

    摘要： The disclosure is directed to a user interface with a menu that facilitates stimulation therapy programming. The user interface displays a representation of the electrical leads implanted in the patient and at least one menu with icons that the user can use to adjust the stimulation therapy. The user may drag one or more field shapes from a field shape selection menu onto the desired location relative to the electrical leads. A manipulation tool menu may also allow the user to adjust the field shapes placed on the electrical leads, which represent the stimulation region. The programmer that includes the user interface then generates electrical stimulation parameter values for the stimulator to deliver stimulation according to the field shapes or field shape groups defined/located by the user. The field shapes may represent different types of stimulation representations, such as current density, activation functions, and neuron models.

    摘要翻译： 本公开针对具有促进刺激治疗编程的菜单的用户界面。 用户界面显示植入患者中的电引线的表示以及具有用户可用于调整刺激疗法的图标的至少一个菜单。 用户可以将一个或多个场形状从场形选择菜单拖到相对于电引线的期望位置上。 操作工具菜单还可以允许用户调整放置在电引线上的场形状，其代表刺激区域。 包括用户界面的程序员然后产生刺激器的电刺激参数值，以根据由用户定义/定位的场形状或场形组递送刺激。 场形状可以表示不同类型的刺激表示，例如电流密度，激活函数和神经元模型。