公开(公告)号：US07341749B2

公开(公告)日：2008-03-11

申请号：US11132183

申请日：2005-05-19

申请人： John L. Hall ,  Sylvie P. Beljanski

发明人： John L. Hall ,  Sylvie P. Beljanski

IPC分类号： A61K36/00 ,  A61K36/89 ,  A61K31/535 ,  A61K31/50

CPC分类号： A61K36/24 ,  A61K31/475 ,  A61K2300/00

摘要： A method and composition for preventing prostate cancer and/or reducing PSA levels and/or alleviating the symptoms of BPH (Benign Prostatic Hyperplasia) or PIN (prostatic intraepithelial neoplasia) by administration of an effective amount of a mixture of flavopereirine and alstonine. A method and composition for treating low-grade prostate cancer and preventing the onset of metastatic disease and/or reducing the doubling time of PSA levels in men with positive biopsies showing relatively low Gleason scores and morphologies characteristic of non-invasive, slow-progressing prostate cancer. The flavopereirine and alstonine can be in the form of natural extracts derived from Pao Pereira and Rauwolfia Vomitoria, respectively. Alternatively, these two active compounds can be administered in purified form. The composition can be in included in a kit along with instructions for use in a treatment regimen.

摘要翻译： 通过施用有效量的黄曲霉素和阿尔斯汀的混合物，预防前列腺癌和/或降低PSA水平和/或减轻BPH（良性前列腺增生症）或PIN（前列腺上皮内瘤变）症状的方法和组合物。 用于治疗低级前列腺癌并预防转移性疾病发作和/或减少具有阳性活组织检查的男性PSA水平倍增时间的方法和组合物显示出相对较低的格列森评分和非侵入性，缓慢进展的前列腺特征的形态 癌症。 黄曲霉素和阿司匹林可以分别是由派佩雷拉（Pao Pereira）和萝维（Rauwolfia Vomitoria）衍生的天然提取物。 或者，这两种活性化合物可以以纯化形式施用。 组合物可以包含在试剂盒中以及用于治疗方案的说明书中。

公开(公告)号：US5470546A

公开(公告)日：1995-11-28

申请号：US264988

申请日：1994-06-24

申请人： John L. Hall

发明人： John L. Hall

IPC分类号： A61L11/00 ,  A61L2/06

CPC分类号： A61L11/00 ,  Y10S588/90

摘要： A fluid tight waste materials receptacle is located within a housing which has an upper access opening through which infectious wastes from medical clinics or the like may be deposited in the receptacle. A lower access opening enables entry and withdrawal of a sterilized waste receiver which may, for example, be a wheeled cart. The receptacle has an open end and a closed end and is pivotable between a first orientation at which the open end is coincident with the upper access opening in order to receive wastes and a second orientation at which the open end is turned downward to discharge wastes into the receiver. A closure pivoted to the housing seats in and seals the open end of the receptacle when it is at the first orientation. The receptacle is periodically evacuated and steam is admitted to sterilize the contents prior to discharge into the receiver.

摘要翻译： 流体密封的废物容器位于壳体内，该壳体具有上部进入开口，来自医疗诊所等的传染性废物可以通过该入口开口沉积在容器中。 下部进入开口使得能够进入和取出例如可以是轮式推车的灭菌废物接收器。 容器具有开口端和封闭端，并且可在第一方向和第二方向之间枢转，第一方位与开口端与上通道开口重合，以便接收废物，第二方向可转动，开口端向下转动以将废物排放到 收件人。 当容器处于第一方向时，闭合件枢转到壳体座部并密封容器的开口端。 定期抽吸容器，并允许蒸汽在放入接收器之前对内容物进行消毒。

公开(公告)号：US4830161A

公开(公告)日：1989-05-16

申请号：US102051

申请日：1987-09-25

申请人： John L. Hall ,  David T. Fenzel ,  Dennis R. Shamine

发明人： John L. Hall ,  David T. Fenzel ,  Dennis R. Shamine

IPC分类号： F01P7/08 ,  F16D25/0632 ,  F16D25/08

CPC分类号： F01P7/085 ,  F16D25/082

摘要： A clutch drive for a vehicle engine cooling fan includes a pulley portion which is driven by the vehicle engine, a fan plate which rotatably mounts the engine cooling fan, and a pressure plate which engages the fan plate to drive the latter when the clutch is engaged. Torque transmission from the pulley to the pressure plate is through a series of circumferentially spaced coiled springs which also yieldabel urge the pressure plate into driving engagement with the fan plate. A spring stabilizer defines a circumferentially extending cavity which receives several coils of the spring to stabilize the latter and to prevent displacement of the coils circumferentially with respect to each other during engagement and disengagement of the clutch. The stabilizer also slidably engages both the pressure plate and the pulley, thereby taking up clearances between the various members to prevent rattling and also to assist in the transmission of torque to the pressure plate.

摘要翻译： 用于车辆发动机冷却风扇的离合器驱动器包括由车辆发动机驱动的滑轮部分，可旋转地安装发动机冷却风扇的风扇板和当离合器接合时与风扇板接合以驱动风扇板的压力板 。 从滑轮到压板的扭矩传递是通过一系列周向间隔开的螺旋弹簧，其也使压力板促使压板与风扇板驱动接合。 弹簧稳定器限定了周向延伸的空腔，其容纳弹簧的若干线圈以稳定弹簧，并且在接合和离合离合器期间防止线圈相对于彼此周向相对移动。 稳定器还可滑动地接合压板和皮带轮，从而吸收各个构件之间的间隙，以防止发出咔嗒声，并且还有助于将扭矩传递到压力板。

公开(公告)号：US4590597A

公开(公告)日：1986-05-20

申请号：US612291

申请日：1984-05-21

申请人： Ma Long-sheng ,  Leo Hollberg ,  Jon H. Shirley ,  John L. Hall

发明人： Ma Long-sheng ,  Leo Hollberg ,  Jon H. Shirley ,  John L. Hall

IPC分类号： H01S3/139 ,  H01S3/13

CPC分类号： H01S3/1392 ,  H01S3/1398

摘要： A method and apparatus are disclosed for precisely stabilizing a laser to a sub-Doppler resonance of an absorbing gas contained in a cell located external to the laser resonator. Stabilization is based on the detection of modulation transferred onto a previously unmodulated probe beam by the non-linear interactions of the absorbing gas located in a cell which is subject to a counter-running, frequency-modulated saturation beam. Alternatively, the further modulation of the saturation beam can be detected.

摘要翻译： 公开了一种用于将激光精确地稳定在包含在位于激光谐振器外部的单元中的吸收气体的亚多普勒共振的方法和装置。 稳定是基于通过位于经受反向运行的频率调制的饱和波束的小区中的吸收气体的非线性相互作用来检测传输到先前未调制的探测光束的调制。 或者，可以检测饱和光束的进一步调制。

公开(公告)号：US628393A

公开(公告)日：1899-07-04

申请号：US1898693408

申请日：1898-10-13

申请人： JOHN L HALL ,  COOPER THOMAS OLIVER

发明人： COOPER THOMAS OLIVER

CPC分类号： B61L29/222

公开(公告)号：US06850543B2

公开(公告)日：2005-02-01

申请号：US10240380

申请日：2001-03-29

申请人： Steven T. Cundiff ,  John L. Hall ,  Scott A. Diddams ,  David J. Jones

发明人： Steven T. Cundiff ,  John L. Hall ,  Scott A. Diddams ,  David J. Jones

IPC分类号： H01S3/098 ,  H01S3/139 ,  H01S3/16 ,  H01S3/10

CPC分类号： H01S3/1112 ,  H01S3/0805 ,  H01S3/0811 ,  H01S3/1307 ,  H01S3/139 ,  H01S3/1398 ,  H01S3/1625 ,  H01S3/1636

摘要： Disclosed is a system and method for stabilizing the carrier-envelope phase of the pulses emitted by a femtosecond mode-locked laser by using the powerful tools of frequency-domain laser stabilization. Control of the pulse-to-pulse carrier-envelope phases was confirmed using temporal cross correlation. This phase stabilization locks the absolute frequencies emitted by the laser, which is used to perform absolute optical frequency measurements that were directly referenced to a stable microwave clock.

摘要翻译： 公开了一种通过使用强大的频域激光稳定工具来稳定由飞秒锁模激光器发射的脉冲的载波包络相位的系统和方法。 使用时间互相关确认脉冲到脉冲载波包络相的控制。 该相位稳定锁定激光器发射的绝对频率，用于执行直接参考稳定微波时钟的绝对光频率测量。

公开(公告)号：US06727492B1

公开(公告)日：2004-04-27

申请号：US09759729

申请日：2001-01-12

申请人： Jun Ye ,  John L. Hall

发明人： Jun Ye ,  John L. Hall

IPC分类号： G01J104

CPC分类号： G01J3/42 ,  G01N21/39

摘要： An ac technique for cavity ringdown spectroscopy permits 1×10−10 absorption sensitivity with microwatt light power. Two cavity modes are provided temporally out of phase such that when one mode is decaying, the other mode is rising. When one of the modes probes intra-cavity absorption of a sample gas, heterodyne detection between the two modes reveals dynamic time constants associated with the cavity and the cavity plus intra-cavity absorption. The system and method provides a quick comparison between on-resonance and off-resonance modes and enables sensitivities that approach the shot-noise limit.

摘要翻译： 空穴沉降光谱的交流技术允许使用微瓦光功率获得1×10 -10的吸收灵敏度。 两个空腔模式在时间上相位提供，使得当一个模式衰减时，另一个模式正在上升。 当其中一种模式探测样品气体的腔内吸收时，两种模式之间的外差检测显示与腔和腔加腔内吸收相关的动态时间常数。 该系统和方法提供了一个快速比较的共振和非共振模式，并使敏感度接近射击噪声极限。

公开(公告)号：US5746988A

公开(公告)日：1998-05-05

申请号：US562508

申请日：1995-11-24

申请人： John L. Hall

发明人： John L. Hall

IPC分类号： A61G12/00 ,  A61L11/00 ,  B09B3/00 ,  A61L2/00

CPC分类号： A61L11/00

摘要： Infectious wastes from hospitals or other sources are sterilized in a chamber which is pivotable between a waste loading orientation, a sterilizing orientation and a waste dumping orientation. The chamber is attached to a framework by first and second pairs of pivot arms which are coupled to the sides of the chamber at spaced apart locations. An actuator swings the first arms upward to bring the chamber to the loading orientation and swings the arms downward to turn the chamber to the dumping orientation. The pivot arm arrangement causes the chamber as a whole to lower as it turns towards the loading orientation and to rise as it turns towards the dumping orientation. This reduces the amount of lifting of materials that is required during loading operations while also providing adequate clearance under the chamber for dumping operations. In one form, the chamber is translatable horizontally between a waste sterilizing location at which a chamber sealing door is situated and a loading and dumping location situated over a waste compactor intake compartment. A plurality of the chambers may be in side-by-side relationship and be loaded, operated and dumped at different times thereby enabling a continuous inflow of waste material.

摘要翻译： 来自医院或其他来源的传染性废物在可在废物装载方向，消毒方向和废物倾倒方向之间枢转的室中灭菌。 腔室通过第一和第二对枢转臂连接到框架，所述枢转臂在间隔开的位置联接到腔室的侧面。 执行器向上摆动第一臂以使腔室处于装载方向并向下摆动臂以将腔室转向倾倒方向。 枢转臂装置使得室整体在朝着装载方向转动时降低，并且随着朝向倾卸方向转动而升高。 这减少了在装载操作期间所需的材料的提升量，同时在室下提供足够的间隙用于倾倒操作。 在一种形式中，室可以在室密封门所在的废物消毒位置和位于废物压实机进气室之间的装载和倾倒位置之间水平地平移。 多个室可以并排关系，并且在不同时间被装载，操作和倾倒，从而能够连续地流入废料。

公开(公告)号：US5218426A

公开(公告)日：1993-06-08

申请号：US723950

申请日：1991-07-01

申请人： John L. Hall ,  Peter J. Martin ,  Mark L. Eickhoff ,  Michael P. Winters

发明人： John L. Hall ,  Peter J. Martin ,  Mark L. Eickhoff ,  Michael P. Winters

IPC分类号： G01J9/02 ,  G01N21/41 ,  G01N21/45

CPC分类号： G01N21/45 ,  G01J2009/0257 ,  G01N2021/4106

摘要： A highly accurate in-situ determination of the refractivity of an ambient atmosphere is disclosed, which determination is utilizable to enhance the accuracy of a quantity measurement. The system includes use of a refractometer exposed to an ambient atmosphere and having light directed thereto to form an optical interference fringe pattern having a dependence upon the refractivity of the ambient atmosphere. The fringe pattern is measured as a function of angle either by sequentially scanning a collimated input beam in angle while collecting and detecting the transmitted light, or by imaging (onto a multi-element detector) the angular exit space of the interferometer illuminated with a diverging input beam. The electrical output of the detector is processed to provide an output indicative of the index of refraction of the ambient atmosphere. The determined index of refraction is utilizable to enhance the accuracy of a quantity measurement, such as, for example, the distance measurement provided by a Fabry-Perot or displacement-measuring Michelson interferometer.

摘要翻译： 公开了对环境大气的折射率的高精度原位测定，该确定可用于提高量测量的精度。 该系统包括使用暴露于环境大气中的折射计，并且具有指向其的光以形成具有依赖于环境大气的折射率的光学干涉条纹图案。 通过在收集和检测透射光的同时顺序地扫描准直的输入光束，或者通过成像（在多元件检测器上）成像（以多元件检测器）照射的干涉仪的角出射空间，将条纹图案作为角度测量， 输入光束。 处理检测器的电输出以提供指示环境大气的折射率的输出。 确定的折射率可用于提高量测量的精度，例如由法布里 - 珀罗或位移测量迈克尔逊干涉仪提供的距离测量。

公开(公告)号：US4237948A

公开(公告)日：1980-12-09

申请号：US960553

申请日：1978-11-14

申请人： Ernest Jones ,  John L. Hall

发明人： Ernest Jones ,  John L. Hall

IPC分类号： B21H3/02 ,  B23G7/00 ,  F16B39/30

CPC分类号： B21H3/025 ,  F16B39/30

摘要： An externally screw threaded member of the self-locking, prevailing torque type has a series of convolutions of a standard thread form, and a locking series of convolutions of the same thread pitch as the standard series but of wider section and with incomplete thread crests. When the member is mated with an internal thread of standard form complementary to the standard series, the locking series of convolutions have an interference fit with the internal thread. In consequence of the interference fit one or both flank portions of each convolution of the locking series are caused to be swaged to some extent towards the crest region.

摘要翻译： 自锁主流扭矩型的外螺纹部件具有标准螺纹形式的一系列卷绕，以及与标准系列相同螺纹螺距的锁定系列，但是具有更宽的部分和不完整的螺纹牙顶。 当与标准系列互补的标准形式的内螺纹配合构件时，锁定系列的卷绕件与内螺纹具有过盈配合。 由于过盈配合，锁定系列的每个卷绕的一个或两个侧面部分被引导到一定程度上朝向顶部区域锻造。