公开(公告)号：US20080147086A1

公开(公告)日：2008-06-19

申请号：US11544846

申请日：2006-10-05

Applicant: Marcus Pfister ,  Michael Maschke ,  Jan Boese ,  Norbert Rahn

Inventor： Marcus Pfister ,  Michael Maschke ,  Jan Boese ,  Norbert Rahn

IPC: A61B19/00

CPC classification number: A61B90/36 ,  A61B34/10 ,  A61B34/20 ,  A61B2034/2051 ,  A61B2090/364

Abstract: Three-dimensional image datasets are used to assist in the visualization of an interventional procedure. The three-dimensional image datasets are registered to two-dimensional images acquired by a medical imaging device. A display device can display a fusion visualization of the three-dimensional image datasets and the two-dimensional image. A monitoring device can monitor the progress of a medical instrument used in the interventional procedure. A processor can incorporate the position of the medical instrument in the fusion visualization displayed by the display device.

Abstract translation: 三维图像数据集用于辅助介入程序的可视化。 将三维图像数据集登记到由医学成像装置获取的二维图像。 显示装置可以显示三维图像数据集和二维图像的融合可视化。 监测装置可以监测介入手术中使用的医疗仪器的进度。 处理器可以将医疗仪器的位置结合在由显示装置显示的融合可视化中。

公开(公告)号：US20080056447A1

公开(公告)日：2008-03-06

申请号：US11897372

申请日：2007-08-30

Applicant: Jan Boese ,  Norbert Rahn

Inventor： Jan Boese ,  Norbert Rahn

IPC: G01N23/04 ,  G06K5/00

CPC classification number: A61B6/504 ,  A61B6/4441 ,  A61B6/541

Abstract: The invention relates to a method for providing a 3D x-ray image data record of a patient, in particular of the heart, by an x-ray imaging system connected to a measuring facility which monitors the breathing phases of the patient. The x-ray image system is automatically activated repeatedly when a predetermined breathing phase is reached and an image acquisition operation is carried out, during which a plurality of 2D x-ray images are recorded. An individual 3D image data record is reconstructed from the 2D x-ray images of each image acquisition operation and the different 3D image data records are registered in pairs in order to assign them in a correct positional and dimensional arrangement. Registration parameters are obtained during the registration. The 3D image data record is reconstructed from 2D x-ray images from all image acquisition operations using the registration parameters.

Abstract translation: 本发明涉及一种用于通过连接到监测患者的呼吸阶段的测量设备的x射线成像系统来提供患者，特别是心脏的3D X射线图像数据记录的方法。 当达到预定呼吸阶段并且执行图像获取操作时，X射线图像系统被重复地自动激活，在此期间记录多个2D X射线图像。 从每个图像获取操作的2D X射线图像重建单独的3D图像数据记录，并且成对登记不同的3D图像数据记录，以便将它们分配在正确的位置和尺寸排列中。 在注册期间获得注册参数。 使用注册参数从所有图像获取操作的2D x射线图像重建3D图像数据记录。

公开(公告)号：US20070248262A1

公开(公告)日：2007-10-25

申请号：US11725517

申请日：2007-03-19

Applicant: Jan Boese ,  Andreas Meyer ,  Norbert Rahn ,  Bernhard Sandkamp

Inventor： Jan Boese ,  Andreas Meyer ,  Norbert Rahn ,  Bernhard Sandkamp

IPC: G06K9/00

CPC classification number: A61B6/541 ,  A61B5/7285 ,  A61B6/503 ,  A61B90/36 ,  A61B90/37 ,  A61B2090/3612 ,  A61B2090/364

Abstract: The present invention relates to a device and a method for synchronizing an image capture device with a first image data set. The image capture device is used for recording a second image data set of a periodically moving area or object. Each first image data set contains information as to the point in time, relative to the periodically moving area or object, when recording took place. The device additionally acquires periodically recurring, current information of the area as well as information concerning the recording instant of the first image data set. From the periodically recurring information and the recording instant of the first image data set, a triggering instant is derived which controls at least one recording of the second image data set by the image capture device in such a way that the second image data set contains image data synchronized to the first image data set.

Abstract translation: 本发明涉及一种用于使图像捕获装置与第一图像数据组同步的装置和方法。 图像捕获装置用于记录周期性移动的区域或对象的第二图像数据集。 当记录发生时，每个第一图像数据集包含关于相对于周期性移动的区域或对象的时间点的信息。 该设备还周期性地获取周期性地重复出现的该区域的当前信息以及关于第一图像数据集的记录时刻的信息。 从第一图像数据集的周期性重复信息和记录时刻，导出触发时刻，其控制由图像捕获装置设置的第二图像数据的至少一次记录，使得第二图像数据集包含图像 与第一图像数据集同步的数据。

公开(公告)号：US20070238952A1

公开(公告)日：2007-10-11

申请号：US11496069

申请日：2006-07-28

Applicant: Jan Boese ,  Martin Kleen ,  Klaus Klingenbeck-Regn ,  Marcus Pfister ,  Norbert Rahn

Inventor： Jan Boese ,  Martin Kleen ,  Klaus Klingenbeck-Regn ,  Marcus Pfister ,  Norbert Rahn

IPC: A61B5/05

CPC classification number: G06T7/55 ,  G06T7/38 ,  G06T7/50 ,  G06T2207/30004

Abstract: The invention relates to a method for registering intra-operative image data set with pre-operative 3D image data set, comprising: spatial calibrating an optical 3D sensor system with an intra-operative imaging modality, intra-operative detecting the surface of an examination area of interest with the 3D sensor system to produce an intra-operative surface mask, intra-operative recording the area of interest for examination with the intra-operative modality at least partly containing the intra-operative surface mask to obtain an intra-operative image data set, computing the same surface from the pre-operative 3D image data set containing the detected surface to obtain a pre-operative surface mask, registering the intra-operative and pre-operative surface mask with each other, determining a mapping specification between pre-operative 3D image data set and intra-operative image data set based on the calibration and the registration, and overlaying the intra-operative image data set with the pre-operative 3D data set based on the mapping specification.

Abstract translation: 本发明涉及一种用于记录术前图像数据组与手术前3D图像数据集的方法，包括：用术中成像模态对光学3D传感器系统进行空间校准，手术中检测检查区域的表面 感兴趣的3D传感器系统以产生术中表面掩模，用至少部分地包含术中表面掩模的手术内模式手术内记录用于检查的感兴趣区域以获得手术中图像数据 设置，从包含检测到的表面的术前3D图像数据集计算相同的表面，以获得术前表面掩模，将手术前和手术前表面掩模彼此对准， 基于校准和注册的手术3D图像数据集和手术中图像数据集，并且将术中图像数据集合与t 他基于映射规范进行手术前3D数据集。

公开(公告)号：US20070232899A1

公开(公告)日：2007-10-04

申请号：US11729756

申请日：2007-03-29

Applicant: Ulrich Bill ,  Jan Boese ,  Norbert Rahn ,  Bernhard Sandkamp

Inventor： Ulrich Bill ,  Jan Boese ,  Norbert Rahn ,  Bernhard Sandkamp

IPC: A61B5/05

CPC classification number: A61B5/06 ,  A61B5/0515 ,  A61B5/062 ,  A61B34/20 ,  A61B90/39 ,  A61B2034/2051 ,  A61B2090/376 ,  A61B2090/3954 ,  A61M25/01

Abstract: The invention is based on a new type of method which can be used to localize magnetizable small particles. According to the invention an invasive instrument, a catheter for example, is provided with a magnetizable marker, whereby a magnetic fluid is arranged in a fluid container. Such an invasive instrument can be localized during an invasive intervention on a patient by using a coil system which on the one hand generates an inhomogeneous basic magnetic field and on the other hand generates a superimposed temporally varying magnetic field. Previous localization methods, which are considerably more complex, can be dispensed with.

Abstract translation: 本发明基于可用于定位可磁化小颗粒的新型方法。 根据本发明，例如具有可磁化标记的入侵器械，例如导管，由此将磁性流体布置在流体容器中。 通过使用一方面产生不均匀的基本磁场并且另一方面产生叠加的时间上不同的磁场的线圈系统，这种侵入性器械可以在对患者的侵入性介入期间进行局部化。 以前的定位方法，这些方法要复杂得多，可以省略。

公开(公告)号：US20070167700A1

公开(公告)日：2007-07-19

申请号：US11314589

申请日：2005-12-21

Applicant: Norbert Rahn ,  Jan Boese ,  Martin Kleen

Inventor： Norbert Rahn ,  Jan Boese ,  Martin Kleen

IPC: A61B5/05

CPC classification number: A61B17/3478 ,  A61B34/20 ,  A61B90/36 ,  A61B2017/00247 ,  A61B2018/00392 ,  A61B2034/2051 ,  A61B2090/374 ,  A61B2090/376 ,  A61K35/12 ,  A61M25/0082 ,  A61M25/0084 ,  A61M2025/0091

Abstract: In a method for accurately delivering a therapeutic agent to a target area of an organ of a living subject, such as for injecting stem cells into the myocardium of the heart, a 3D image, in which the target area and a delivery path thereto are visible, is obtained prior to delivery of the therapeutic agent. The 3D image is displayed, and a catheter is introduced into the subject and a real time positional indication of the catheter in the subject is obtained and incorporated into the displayed image, providing visual support for guiding the catheter to the target area. When the catheter is at the target area, the therapeutic agent is injected into the target area via the catheter. The distribution of the injected therapeutic agent relative to the target area is then monitored in the displayed image.

Abstract translation: 在将用于将干细胞注入心脏心脏的活体受试者的器官的目标区域精确输送的方法中，其中目标区域和其输送路径可见的3D图像 在递送治疗剂之前获得。 显示3D图像，并且将导管引入到对象中，并且获得被检体内的导管的实时位置指示并将其合并到所显示的图像中，从而提供用于将导管引导到目标区域的视觉支撑。 当导管位于目标区域时，经由导管将治疗剂注入目标区域。 然后在所显示的图像中监测注射的治疗剂相对于目标区域的分布。

公开(公告)号：US20070086633A1

公开(公告)日：2007-04-19

申请号：US11526176

申请日：2006-09-22

Applicant: Jan Boese ,  Marcus Pfister ,  Norbert Rahn ,  Bernhard Sandkamp

Inventor： Jan Boese ,  Marcus Pfister ,  Norbert Rahn ,  Bernhard Sandkamp

IPC: G06K9/00

CPC classification number: A61B90/36 ,  A61B34/10 ,  A61B34/20

Abstract: With a method for supporting an interventional medical operation, a 3-dimensional image data set is recorded before the method. A positioning system is coupled with the coordinates system of the 3-dimensional image data set. The instrument is positioned and the position of the instrument in the 3-dimensional image data set is determined as an instrument image data point 4. Two further target image data points are determined in the target region, in which the instrument is to be guided. A plane is defined in this way. In this plane, the image data is used for a 2-dimensional display. Both the instrument image data point and also the two target image data points can be identified on the display, so that the target region of an interventional operation and an interventional medical device are displayed on an image at the same time. The image can be tracked during the interventional medical operation.

Abstract translation: 利用支持介入医疗操作的方法，在方法之前记录三维图像数据集。 定位系统与三维图像数据集的坐标系相结合。 将仪器定位，并将仪器在3维图像数据组中的位置确定为仪器图像数据点4.在目标区域中确定另外的目标图像数据点，其中仪器将被引导。 以这种方式定义飞机。 在该平面中，图像数据用于二维显示。 可以在显示器上识别仪器图像数据点和两个目标图像数据点，使得介入操作的目标区域和介入医疗装置同时显示在图像上。 在介入医疗操作期间可以跟踪图像。

公开(公告)号：US20070083103A1

公开(公告)日：2007-04-12

申请号：US11529681

申请日：2006-09-28

Applicant: Jan Boese ,  Martin Kleen ,  Andreas Meyer ,  Marcus Pfister ,  Norbert Rahn

Inventor： Jan Boese ,  Martin Kleen ,  Andreas Meyer ,  Marcus Pfister ,  Norbert Rahn

IPC: A61B5/05

CPC classification number: G01B21/20 ,  A61B5/06 ,  A61B5/062 ,  A61B6/4441 ,  A61B6/467 ,  A61B6/5235

Abstract: The invention relates to an arrangement having a 3D device, the 3D device being embodied for acquiring an objects and generating a 3D acquisition result representing the object at least partially in at least three dimensions. The arrangement also has a 2D device, the 2D device being embodied for acquiring the object and generating a 2D acquisition result representing the object in at least two dimensions. The 2D acquisition result represents the object at least partially, in particular a top view of the object, a view through the object or a section through the objects. The invention is characterized in that the 3D devices and the 2D devices are connected to one another, mechanically electrically, in such a way that a part of the 3D acquisition result corresponding to an object location can be assigned to a part of the 2D acquisition result corresponding to the same object location.

Abstract translation: 本发明涉及一种具有3D装置的装置，该3D装置被实施为用于获取对象并且至少部分地至少三维地生成表示该对象的3D采集结果。 该装置还具有2D设备，2D设备被实现为用于获取对象并在至少二维中生成表示对象的2D采集结果。 2D采集结果至少部分地表示对象，特别是对象的顶视图，通过对象的视图或通过对象的部分。 本发明的特征在于，3D装置和2D装置彼此机械电连接，使得对应于对象位置的3D采集结果的一部分可被分配给2D采集结果的一部分 对应于相同的对象位置。

公开(公告)号：US20070078325A1

公开(公告)日：2007-04-05

申请号：US10569958

申请日：2004-08-19

Applicant: Kristine Fuimaono ,  Gal Hayam ,  Yuval Karmi ,  Reinmar Killmann ,  Assaf Preiss ,  Norbert Rahn ,  Frank Sauer ,  Chenyang Xu

Inventor： Kristine Fuimaono ,  Gal Hayam ,  Yuval Karmi ,  Reinmar Killmann ,  Assaf Preiss ,  Norbert Rahn ,  Frank Sauer ,  Chenyang Xu

IPC: A61B18/18 ,  A61B5/05

CPC classification number: A61B6/032 ,  A61B5/055 ,  A61B5/7285 ,  A61B6/5247 ,  A61B6/541 ,  A61B8/14 ,  A61B8/543 ,  A61B18/1492 ,  A61B2018/00375 ,  A61B2018/00839 ,  G01R33/5608

Abstract: A method and a device are disclosed for visually supporting an electrophysiology catheter application in the heart, whereby electroanatomical 3D mapping data of an area of the heart to be treated which are provided during performance of the catheter application are visualized. Before the catheter application is carried out, 3D image data of the area to be treated are recorded by way of a tomographical 3D imaging method, a 3D surface profile of objects in the area to be treated is extracted from the 3D image data by segmentation and the electroanatomical 3D mapping data provided and the 3D images representing the 3D surface profile are associated with each other in the correct position and dimension relative each other and e.g. visualized in a superimposed manner during the catheter application. The disclosed method and the corresponding device allow for an improved orientation of the user who carries out an electrophysiology catheter application in the heart.

Abstract translation: 公开了用于视觉上支持心脏中的电生理学导管应用的方法和装置，由此可视化在执行导管应用过程中提供的待治疗心脏区域的电解剖3D图。 在执行导管应用之前，通过断层3D成像方法记录待处理区域的3D图像数据，通过分割从3D图像数据中提取待处理区域中的对象的3D表面轮廓， 所提供的电解剖3D图形数据和表示3D表面轮廓的3D图像彼此相对彼此相关联，并且例如彼此相对。 在导管应用期间以叠加的方式可视化。 所公开的方法和相应的装置允许在心脏中进行电生理学导管应用的用户的改进的取向。

公开(公告)号：US20070004981A1

公开(公告)日：2007-01-04

申请号：US11480192

申请日：2006-06-30

Applicant: Jan Boese ,  Norbert Rahn ,  Bernhard Sandkamp

Inventor： Jan Boese ,  Norbert Rahn ,  Bernhard Sandkamp

IPC: A61M25/00 ,  A61M25/098 ,  A61B6/00 ,  A61B8/14

CPC classification number: A61M25/0108 ,  A61M2025/0008 ,  A61M2025/1079

Abstract: To make interventional instruments such as catheters more easily identifiable in X-ray images, the catheters are provided with marking elements which can be recognized in the X-ray image. Examples of marking elements are sphere-shaped and ring-shaped marking elements, the ring-shaped marking elements being able to identify the catheters in the manner of a barcode and so being able to make different catheters distinguishable from one another in the X-ray image.

Abstract translation: 为了在X射线图像中更容易识别诸如导管之类的介入仪器，导管设置有可在X射线图像中识别的标记元件。 标记元件的示例是球形和环形标记元件，环形标记元件能够以条形码的方式识别导管，并且能够使得在X射线中彼此可区分的不同导管 图片。