公开(公告)号：US20130115619A1

公开(公告)日：2013-05-09

申请号：US13695263

申请日：2011-04-28

Applicant: Jonathan Peter Clark

Inventor： Jonathan Peter Clark

IPC: G01N33/68

CPC classification number: G01N33/68 ,  C12Q1/25 ,  G01N2333/9015

Abstract: The present invention related to a method of assaying ubiquitination in a sample by combining ubiquitin and two or more of E1, E2, E3 and a substrate protein in a sample under conditions suitable for ubiquitination to take place, exposing the sample with a labelled binding partner which is specific for the ubiquitin and measuring the amount of labelled ubiquitin bound to any one of the components in the sample, wherein one or more of the components in the sample comprises an immobilisation tag which facilitates its immobilisation onto a solid surface.

Abstract translation: 本发明涉及通过将样品中的遍在蛋白和E1，E2，E3和底物蛋白质中的两种或更多种在适于泛素化的条件下将样品中的泛蛋白组合进行测定的方法，将其用标记的结合配偶体 其对于泛素是特异性的，并且测量与样品中任一组分结合的标记的泛素的量，其中样品中的一种或多种组分包含有助于其固定在固体表面上的固定标签。

公开(公告)号：US20120092543A1

公开(公告)日：2012-04-19

申请号：US13318440

申请日：2010-05-03

Applicant: Bahram Afshari ,  John Toor ,  Samuel Wennyann Ho ,  Peter Clark

Inventor： Bahram Afshari ,  John Toor ,  Samuel Wennyann Ho ,  Peter Clark

IPC: H04N5/225 ,  G02F1/29

CPC classification number: H04N5/2254 ,  H04N5/2257 ,  Y10T29/49002 ,  Y10T29/49004

Abstract: An electrically controllable optical lens apparatus makes use of fixed lenses and an active optical element together in a lens enclosure. The enclosure may be a barrel structure that is easily mounted to a camera device having an image sensor. The active optical element, such as a tunable liquid crystal lens, receives an electrical signal from the camera device via electrical conductors integral with the lens enclosure that provide electrical pathways between the active element on the interior of the enclosure and surface contacts on the camera device. The enclosure may be a two-piece structure, and the electrical conductors may be attached to either piece of the structure. The lens enclosure may also be threaded for attachment to the camera device. The electrical conductors may also use spring loaded contact portions or molded interconnect devices.

Abstract translation: 电可控光学透镜装置将透镜外壳中的固定透镜和有源光学元件一起使用。 外壳可以是容易地安装到具有图像传感器的相机装置的筒结构。 有源光学元件，例如可调谐液晶透镜，经由与透镜外壳成一体的电导体从相机装置接收电信号，该电导体提供在外壳内部的有源元件与相机装置上的表面触点之间的电通路 。 外壳可以是两件式结构，并且电导体可以附接到结构的任一片。 透镜外壳也可以被螺纹连接到相机装置。 电导体还可以使用弹簧加载的接触部分或模制的互连装置。

公开(公告)号：US5965213A

公开(公告)日：1999-10-12

申请号：US930160

申请日：1998-02-02

Applicant: Lawrence Sacharski ,  Joachim Woltering ,  Peter Clark ,  Heinrich Wonnemann

Inventor： Lawrence Sacharski ,  Joachim Woltering ,  Peter Clark ,  Heinrich Wonnemann

IPC: C08G59/32 ,  C08G59/42 ,  B05D1/04 ,  C08K5/092 ,  C08K5/205

CPC classification number: C08G59/4207 ,  C08G59/3209 ,  Y10S524/902 ,  Y10S524/904 ,  Y10S525/934 ,  Y10S526/932

Abstract: Disclosed is an aqueous dispersion of a transparent powder coating consisting of a solid powder component and an aqueous component. The solid powder component includes at least one epoxy group-containing binder, at least one crosslinking agent, and optionally catalysts, adjuvants, or additives typical for transparent powder coatings. The binder contains 30-45% glycidyl-containing monomers and optionally vinylaromatic compounds such as styrene. The crosslinking agent is preferably a straight-chain aliphatic dicarboxylic acid and/or a carboxy-functional polyester. The aqueous component includes at least one nonionic thickener and optional materials such as catalysts, adjuvants, and/or other such materials. The nonionic thickener is preferably a nonionic associative thickener. The invention also provides a process for preparing the aqueous dispersion of the invention and a process for coating a vehicle body with the aqueous dispersion of the invention.

Abstract translation: PCT No.PCT / EP96 / 01480 Sec。 371日期1998年2月2日 102（e）1998年2月2日PCT 1996年4月4日PCT PCT。 第WO96 / 32452号公报 日期1996年10月17日公开是由固体粉末组分和水性组分组成的透明粉末涂料的水分散体。 固体粉末组分包括至少一种含环氧基的粘合剂，至少一种交联剂，以及任选的催化剂，助剂或通常用于透明粉末涂料的添加剂。 粘合剂含有30-45％的含缩水甘油基的单体和任选的乙烯基芳族化合物如苯乙烯。 交联剂优选为直链脂族二羧酸和/或羧基官能聚酯。 含水组分包括至少一种非离子增稠剂和任选的材料，例如催化剂，助剂和/或其它这样的材料。 非离子增稠剂优选为非离子缔合增稠剂。 本发明还提供了制备本发明的水性分散体的方法和用本发明的水性分散体涂布车体的方法。

公开(公告)号：US5863947A

公开(公告)日：1999-01-26

申请号：US853285

申请日：1997-05-09

Applicant: Stephen Richard Baker ,  Barry Peter Clark ,  John Goldsworthy ,  John Richard Harris

Inventor： Stephen Richard Baker ,  Barry Peter Clark ,  John Goldsworthy ,  John Richard Harris

IPC: C07D295/14 ,  A61K31/195 ,  A61K31/245 ,  A61K31/34 ,  A61K31/341 ,  A61K31/38 ,  A61K31/381 ,  A61K31/40 ,  A61P1/08 ,  A61P25/04 ,  A61P25/18 ,  C07C229/36 ,  C07C229/38 ,  C07C259/10 ,  C07C305/24 ,  C07C309/58 ,  C07C313/02 ,  C07D257/04 ,  C07D295/155 ,  C07D307/54 ,  C07D333/24 ,  C07D521/00 ,  C07F9/09 ,  C07F9/40 ,  C07C321/28

CPC classification number: C07D295/155 ,  C07C229/36 ,  C07C229/38 ,  C07D307/54 ,  C07D333/24

Abstract: A pharmaceutical compound of the formula: ##STR1## in which R.sup.1 is hydrogen, hydroxy or C.sub.1-6 alkoxy, R.sup.2 is hydrogen, carboxy, tetrazolyl, --SO.sub.2 H, --SO.sub.3 H, --OSO.sub.3 H, --CONHOH, or --P(OH)OR', --PO(OH)OR', --OP(OH)OR' or --OPO(OH)OR' where R' is hydrogen, C.sub.1-6 alkyl, C.sub.2-6 alkenyl or aryl C.sub.1-6 alkyl,R.sup.3 is hydrogen, hydroxy or C.sub.1-4 alkoxy, andR.sup.4 is fluoro, trifluoromethyl, nitro, C.sub.1-6 alkyl, C.sub.3-7 cycloalkyl, C.sub.2-6 alkenyl, C.sub.2-6 alkynyl, C.sub.1-6 alkylthio, heteroaryl, optionally substituted aryl, optionally substituted aryl C.sub.1-6 alkyl, optionally substituted aryl C.sub.2-6 alkenyl, optionally substituted aryl C.sub.2-6 alkynyl, optionally substituted aryloxy, optionally substituted aryl C.sub.1-6 alkoxy, optionally substituted arylthio, optionally substituted aryl C.sub.1-6 alkylthio or --CONR"R'", --SO.sub.2 NR"R"", --NR"R'", --OCONR"R"' or --SONR"R'" where R" and R'" are each hydrogen, C.sub.1-6 alkyl or aryl C.sub.1-6 alkyl, or R" and R'" together form a C.sub.3-7 alkylene ring;provided that (i) R.sup.1, R.sup.2 and R.sup.3 are not all hydrogen,and (ii) when R.sup.2 and R.sup.3 are hydrogen and R.sup.1 is hydroxy, R.sup.4 is not fluoro;or a salt or ester thereof.

Abstract translation: 下式的药物化合物：其中R 1是氢，羟基或C 1-6烷氧基，R 2是氢，羧基，四唑基，-SO 2 H，-SO 3 H，-OSO 3 H，-CONHOH或-P（ OH）OR'，-PO（OH）OR'，-OP（OH）OR'或-OPO（OH）OR'，其中R'是氢，C 1-6烷基，C 2-6烯基或芳基C 1-6烷基， R3是氢，羟基或C1-4烷氧基，R4是氟，三氟甲基，硝基，C1-6烷基，C3-7环烷基，C2-6烯基，C2-6炔基，C1-6烷硫基，杂芳基，任选取代的芳基 ，任选取代的芳基C 1-6烷基，任选取代的芳基C 2-6烯基，任选取代的芳基C 2-6炔基，任选取代的芳氧基，任选取代的芳基C 1-6烷氧基，任选取代的芳硫基，任选取代的芳基C 1-6烷硫基或 - CONR''R“'，-SO2NR''R”'，-NR''R“'，-OCONR''R”'或-SONR''R“'，其中R”和R“ “各自为氢，C 1-6烷基或芳基C 1-6烷基，或R”和R“”一起形成C 3-7亚烷基环; 条件是（i）R 1，R 2和R 3不全部为氢，和（ii）当R 2和R 3为氢且R 1为羟基时，R 4不为氟; 或其盐或酯。

公开(公告)号：US5731987A

公开(公告)日：1998-03-24

申请号：US666369

申请日：1996-06-20

Applicant: John Strong ,  Peter Clark ,  Nigel Harrison ,  Christopher Watson

Inventor： John Strong ,  Peter Clark ,  Nigel Harrison ,  Christopher Watson

IPC: B66C23/687 ,  B66C23/693 ,  B66C23/70 ,  B66C23/90 ,  B66C23/00

CPC classification number: B66C23/705 ,  B66C23/905

Abstract: An operating system for telescoping a telescopic boom for a crane, particularly a boom having three or more telescoping sections, enabling the boom to be extended and retracted automatically under load according to a predetermined sequence which optimises the load capacity of the boom and the stability of the crane. The boom may be switched rapidly between modes of operation in one of which all of the telescoping sections may extend or retract and in another of which at least one telescoping section is maintained in the fully retracted position.

Abstract translation: PCT No.PCT / GB94 / 02790第 371日期：1996年6月20日 102（e）日期1996年6月20日PCT 1994年12月22日PCT PCT。 WO95 / 17343 PCT出版物 日期1995年6月29日一种用于伸缩起重机的伸缩臂的操作系统，特别是具有三个或更多个伸缩部分的起重臂，使得吊杆可以根据预定的顺序在负载下自动伸长和缩回，该顺序优化了 起重机和起重机的稳定性。 可以在操作模式之间快速切换吊杆，其中一个伸缩部分可延伸或缩回，并且另一个伸缩部分中至少一个伸缩部分保持在完全缩回位置。

公开(公告)号：US1922525A

公开(公告)日：1933-08-15

申请号：US60236932

申请日：1932-03-31

Applicant: PETER CLARK

Inventor： PETER CLARK

IPC: E04H3/26

CPC classification number: E04H3/26

公开(公告)号：US08854527B2

公开(公告)日：2014-10-07

申请号：US13318440

申请日：2010-05-03

Applicant: Bahram Afshari ,  John Toor ,  Samuel Wennyann Ho ,  Peter Clark

Inventor： Bahram Afshari ,  John Toor ,  Samuel Wennyann Ho ,  Peter Clark

IPC: H04N5/225

CPC classification number: H04N5/2254 ,  H04N5/2257 ,  Y10T29/49002 ,  Y10T29/49004

Abstract: An electrically controllable optical lens apparatus makes use of fixed lenses and an active optical element together in a lens enclosure. The enclosure may be a barrel structure that is easily mounted to a camera device having an image sensor. The active optical element, such as a tunable liquid crystal lens, receives an electrical signal from the camera device via electrical conductors integral with the lens enclosure that provide electrical pathways between the active element on the interior of the enclosure and surface contacts on the camera device. The enclosure may be a two-piece structure, and the electrical conductors may be attached to either piece of the structure. The lens enclosure may also be threaded for attachment to the camera device. The electrical conductors may also use spring loaded contact portions or molded interconnect devices.

Abstract translation: 电可控光学透镜装置将透镜外壳中的固定透镜和有源光学元件一起使用。 外壳可以是容易地安装到具有图像传感器的相机装置的筒结构。 有源光学元件，例如可调谐液晶透镜，经由与透镜外壳成一体的电导体从相机装置接收电信号，该电导体提供在外壳内部的有源元件与相机装置上的表面触点之间的电通路 。 外壳可以是两件式结构，并且电导体可以附接到结构的任一片。 透镜外壳也可以被螺纹连接到相机装置。 电导体还可以使用弹簧加载的接触部分或模制的互连装置。

公开(公告)号：US08824134B2

公开(公告)日：2014-09-02

申请号：US13275773

申请日：2011-10-18

Applicant: Chao-Ming Chu ,  Peter Clark Timothy

Inventor： Chao-Ming Chu ,  Peter Clark Timothy

IPC: G06F1/16 ,  H05K5/00 ,  H05K7/00

CPC classification number: G06F1/166

Abstract: A tablet electronic device is disclosed. The tablet electronic device includes a first side, a second side and an electronic component. The first side has a first thickness. The second side is opposite to the first side and has a second thickness. The second thickness is larger than the first thickness. The second side has a recess. The electronic component is accommodated in the recess such that a gravity center of the tablet electronic device is adjusted towards the second side. The tablet electronic device has a holding portion and the center of gravity of the tablet electronic device is arranged in a suitable position, thus the tablet electronic device disclosed herein can be comfortably operated while being held in a user's hand. Furthermore, the tablet electronic device can be set in various ways for comfortable usage.

Abstract translation: 公开了一种平板电子设备。 平板电子设备包括第一侧，第二侧和电子部件。 第一侧具有第一厚度。 第二侧与第一侧相对并且具有第二厚度。 第二厚度大于第一厚度。 第二面有凹槽。 电子部件容纳在凹部中，使得平板电子装置的重心朝向第二侧被调节。 平板电子设备具有保持部分，并且平板电子设备的重心布置在合适的位置，因此本文公开的平板电子设备可以在被握持在用户的手中的同时舒适地操作。 此外，平板电子设备可以以各种方式设置为舒适的使用。

公开(公告)号：US20120241150A1

公开(公告)日：2012-09-27

申请号：US13188539

申请日：2011-07-22

Applicant: Ahmed Hamed AL YAHYAI ,  Felix Antonio ASCANIO MILANO ,  Jose Luis CHAVARRIA ,  Hamish Peter CLARK ,  Cornelis Petrus Josephus Walthera VAN KRUIJSDIJK ,  William H. WILLIAMS ,  Mirko ZATKA

Inventor： Ahmed Hamed AL YAHYAI ,  Felix Antonio ASCANIO MILANO ,  Jose Luis CHAVARRIA ,  Hamish Peter CLARK ,  Cornelis Petrus Josephus Walthera VAN KRUIJSDIJK ,  William H. WILLIAMS ,  Mirko ZATKA

IPC: E21B43/22

CPC classification number: E21B43/2406 ,  E21B43/14 ,  E21B43/162

Abstract: A method for producing oil from an underground formation comprising providing a first well in one or more formations, the first well comprising a plurality of sections along a length of the well; providing a second well in the formation; injecting an enhanced oil recovery formulation into at least a first section and a second section of the first well and into the formation; flowing the formulation and/or oil towards the second well in one or more formations; producing the formulation and/or oil from the second well; and then modifying the injecting into the second section, while continuing the injecting into the first section.

Abstract translation: 一种从地下地层生产油的方法，包括在一个或多个地层中提供第一井，所述第一井包括沿所述井的长度的多个段; 在地层中提供第二口井; 将增强的采油配方注入至少第一井的第一段和第二段并进入地层; 在一个或多个地层中将制剂和/或油流向第二井; 从第二井产生制剂和/或油; 然后修改注入到第二部分，同时继续注入第一部分。

公开(公告)号：US07615648B2

公开(公告)日：2009-11-10

申请号：US11568641

申请日：2005-05-19

Applicant: John Richard Harris ,  Barry Peter Clark ,  Peter Thaddeus Gallagher ,  Maria Ann Whatton

Inventor： John Richard Harris ,  Barry Peter Clark ,  Peter Thaddeus Gallagher ,  Maria Ann Whatton

IPC: C07D207/00 ,  A01N43/36

CPC classification number: C07D207/09 ,  C07D405/12 ,  C07D493/08

Abstract: The present invention provides compounds of formula (I) wherein A is (1), (2), (3), (4), (5), (6) or (7) and wherein R1, R7, y and Ar1 are defined herein. The compounds are inhibitors of the uptake of one or more monoamines selected from serotonin, norepinephrine and dopamine and, as such, may be useful in the treatment of disorders of the central and/or peripheral nervous system.

Abstract translation: 本发明提供式（I）化合物，其中A是（1），（2），（3），（4），（5），（6）或（7），其中R 1，R 7，Y和Ar 1是 本文定义。 这些化合物是一种或多种选自5-羟色胺，去甲肾上腺素和多巴胺的单胺摄取的抑制剂，因此可用于治疗中枢和/或周围神经系统疾病。