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21.发明申请公开(公告)号：US20230130676A1
公开(公告)日：2023-04-27
申请号：US17908629
申请日：2021-03-04
Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION
Inventor： Sun IM , Seungchul LEE , Juhyeong JEON , Young Hoon JOO , Yeon Jae HAN
IPC: G16H50/20
Abstract: An apparatus for diagnosing a disease and a method for diagnosing a disease, in which: a plurality of voice signals are received to generate a first image signal and a second image signal which are image signals for each voice signal; a plurality of disease probability information for a target disease causing a voice change are extracted by using an artificial intelligence model determined according to the type of each voice signal and a generation method used to generate each image signal for the first image signal and the second image signal for each voice signal; and it is determined whether the target disease is negative or positive on the basis of the plurality of disease probability information.
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公开(公告)号：US20230023432A1
公开(公告)日：2023-01-26
申请号：US17381564
申请日：2021-07-21
Applicant: Min Jeong WANG , THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , GIL MEDICAL CENTER , Inha University Research and Business Foundation
Inventor： Dong Won YANG , Sang Yun KIM , Kee Hyung PARK , Jee Hyang JEONG , Seong Hye CHOI , Yun Jeong HONG , Min Jeong WANG
Abstract: There is provided a method for determining dementia risk factors by a server using deep learning. In this instance, the method for determining dementia risk factors includes acquiring biometric information from each subject corresponding to a first control group through a wearable device, acquiring measurement information for each subject corresponding to the first control group, deriving a first dementia risk factor based on the biometric information and the measurement information for each subject, and deriving a second dementia risk factor related to the first dementia risk factor via deep learning performed based on the biometric information related to the first dementia risk factor and control group information.
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公开(公告)号：US20230022039A1
公开(公告)日：2023-01-26
申请号：US17784193
申请日：2020-12-08
Inventor： Min Wook JOO
Abstract: A bone tumor surgery device according to an embodiment of the present invention comprises: an accommodation container in which an accommodation space for accommodating a bone of a patient is formed; and a radiofrequency supply unit for supplying radiofrequency into the accommodation space.
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24.发明申请公开(公告)号：US20220389065A1
公开(公告)日：2022-12-08
申请号：US17789300
申请日：2021-05-07
Inventor： Seok-Goo CHO , Keon-IL IM , Nayoun KIM , Young-Woo JEON , Yunejin SONG , Junseok LEE
IPC: C07K14/195 , A61K38/16 , C07K16/28
Abstract: The present invention relates to an anticancer drug composition comprising, as an active ingredient, TLR5 agonist derived from flagellin. The TLR5 agonist derived from flagellin of the present invention can exhibit an anticancer or anticancer adjuvant effect alone or concurrently with an immune checkpoint blockade, and thus, can be developed as a cancer cell growth inhibitory active ingredient.
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公开(公告)号：US20220362456A1
公开(公告)日：2022-11-17
申请号：US17616711
申请日：2020-06-04
Inventor： Hyunjung KOH
Abstract: The present invention relates to an extensible drug injection device capable of injecting a drug from a location away from a patient, and an operation method therefor. Disclosed is a drug injection device comprising: a first sub-line of which one end joins with a main line, connected from a first drug storage part for storing a first drug to be injected into a patient to the body of the patient such that the first drug flows therein, and of which the other end is extended to the other side; a second drug injection part which is connected to the first sub-line and which injects a second drug that is different from the first drug; and a second drug pumping part which is connected to the first sub-line, and which pushes, to the main line, the second drug having been injected by the second drug injection part into the first sub-line.
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Patent Agency Ranking
公开(公告)号：US20220356533A1
公开(公告)日：2022-11-10
申请号：US17774424
申请日：2020-10-23
Inventor： Chan Kwon JUNG , Seung Hyun JUNG , Yeun Jun CHUNG
IPC: C12Q1/6886 , C12Q1/6827
Abstract: The present invention relates to: a biomarker composition for diagnosing or predicting the prognosis of thyroid cancer, comprising a preparation capable of detecting a mutation in a PLEKHS1 promoter gene; and a use thereof. The biomarker composition for diagnosing or predicting the prognosis of thyroid cancer of the present invention confirms whether a mutation is present in a PLEKHS1 promoter gene, and thus can provide information needed for diagnosing metastatic (distant metastatic) differentiated thyroid cancer, and also confirms whether a mutation is present in BRAF, TERT promoter, three types of RAS and a TP53 gene in addition to the PLEKHS1 promoter gene, and thus, with respect to radioactive iodine therapy response and survival, can classify the prognosis of a metastatic differentiated thyroid cancer patient into one of three prognosis groups, and predict the same.
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公开(公告)号：US20220218786A1
公开(公告)日：2022-07-14
申请号：US17441604
申请日：2020-03-26
Inventor： Seok-Goo CHO , Keon-IL IM , Nayoun KIM , Young-Woo JEON , Young-Sun NAM , Yunejin SONG , Junseok LEE
Abstract: The present disclosure relates to a composition for preventing or treating graft-versus-host disease (GVHD) containing a TLR5 agonist derived from flagellin as an active ingredient. The TLR5 agonist derived from flagellin according to the present disclosure exhibits an excellent therapeutic effect against GVHD, and thus may be developed as an active ingredient for a composition for the treatment, prevention or alleviation of GVHD.
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公开(公告)号：US20220110787A1
公开(公告)日：2022-04-14
申请号：US17265411
申请日：2020-09-21
Inventor： Sung Soo PARK , Byung Hee HWANG , Chang Ki MIN , Jong Hyuk LEE
Abstract: Proposed is an oral cooling device using a cooling balloon, including: a cooling water supply portion provided with a cooler that cools cooling water and a pump that supplies and recovers the cooling water; a cooling water hose portion connected to the cooling water supply portion to transfer the supplied cooling water and recover the recovered cooling water to the cooling water supply portion; and a cooling balloon portion which is connected to an end portion of the cooling water hose portion, expands by the supplied cooling water to cool an inside of an oral cavity of a patient after being inserted into a mouth of the patient, and contracts in a case where the cooling water is recovered to the cooling water supply portion.
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公开(公告)号：US20220031637A1
公开(公告)日：2022-02-03
申请号：US17290637
申请日：2019-11-07
Inventor： Mi-La CHO , Dong-Yun SHIN , Jong-Young CHOI , Chul-Woo YANG , Sung-Hwan PARK , Seon-Yeong LEE , Min-Jung PARK , Joo-Yeon JHUN , Se-Young KIM , Hyeon-Beom SEO , Jae-Yoon RYU , Keun-Hyung CHO
IPC: A61K31/155 , A61K31/436 , A61K38/13 , A61P37/06
Abstract: The present invention relates to a composition for preventing or treating transplantation rejection or a transplantation rejection disease, comprising a novel compound and a calcineurin inhibitor. A co-administration of the present invention 1) reduces the activity of pathogenic Th1 cells or Th17 cells, 2) increases the activity of Treg cells, 3) has an inhibitory effect against side effects, such as tissue damage, occurring in the sole administration thereof, 4) inhibits various pathogenic pathways, 5) inhibits the cell death of inflammatory cells, and 6) increases the activity of mitochondria, in an in vivo or in vitro allogenic model, a transplantation rejection disease model, a skin transplantation model, and a liver-transplanted patient, and thus inhibits transplantation rejection along with mitigating side effects possibly occurring in the administration of a conventional immunosuppressant alone. Thus, the present invention may be used in the field of pharmaceutics relating to transplantation rejection or various immune disorders possibly occurring after transplantation.
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公开(公告)号：US20220031450A1
公开(公告)日：2022-02-03
申请号：US17274684
申请日：2018-12-19
Applicant: Hyung Gu KWON , THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventor： Hyung Gu KWON , Dong Jin CHANG , Young Jung ROH , Jae Hyung HAN
IPC: A61F2/16
Abstract: Provided is an intraocular lens exchanger for moving a foldable intraocular lens (IOL), the intraocular lens exchanger including: an outer tube having a first passage formed in a forward/rearward direction; an inner tube disposed to be movable along the first passage and having a second passage formed in the forward/rearward direction; and a variable tube extending from a front end of the inner tube to form a variable passage connected to the second passage, in which the variable tube has an extension part having a width that increases forward in an unconstrained state in which the variable tube is not positioned in the first passage, and the extension part is provided to be elastically deformed when the unconstrained state changes to a constrained state in which at least a part of the extension part is received in the first passage.
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