公开(公告)号：US08127618B1

公开(公告)日：2012-03-06

申请号：US11750575

申请日：2007-05-18

Applicant: Yong D. Zhao ,  Apratim Dixit

Inventor： Yong D. Zhao ,  Apratim Dixit

IPC: G01L7/00 ,  A61N1/365

CPC classification number: A61B5/0215 ,  A61B5/686 ,  A61B5/6869 ,  A61B2562/0247 ,  A61B2562/0271 ,  A61B2562/028 ,  A61N1/056 ,  A61N1/3702 ,  G01L9/0073 ,  G01L27/002

Abstract: The disclosure relates in some aspects to an implantable pressure sensor and a method of measuring pressure. In some embodiments pressure may be measured through the use of an implantable lead incorporating one or more pressure sensors. In some aspects a pressure sensor is implemented in a micro-electromechanical system (“MEMS”) that employs direct mechanical sensing. A biocompatible material is attached to one or more portions of the MEMS sensor to facilitate implant in a body of a patient. The MEMS sensor may thus be incorporated into an implantable lead for measuring blood pressure in, for example, one or more chambers of the patient's heart.

Abstract translation: 本公开在一些方面涉及可植入压力传感器和测量压力的方法。 在一些实施例中，可以通过使用结合有一个或多个压力传感器的可植入引线来测量压力。 在一些方面，在采用直接机械感测的微机电系统（“MEMS”）中实现压力传感器。 生物相容性材料附接到MEMS传感器的一个或多个部分以便于植入患者体内。 因此，MEMS传感器可以被结合到可植入引线中，用于测量例如患者心脏的一个或多个腔室中的血压。

公开(公告)号：US08099171B2

公开(公告)日：2012-01-17

申请号：US12495612

申请日：2009-06-30

Applicant: Virote Indravudh ,  Yong D. Zhao ,  Kevin L. Morgan ,  Dion F. Davis ,  Grace Jang

Inventor： Virote Indravudh ,  Yong D. Zhao ,  Kevin L. Morgan ,  Dion F. Davis ,  Grace Jang

IPC: A61N1/00

CPC classification number: A61N1/05 ,  A61N1/086

Abstract: An implantable medical lead configured for improved MRI safety and heating reduction performance is disclosed herein. In one embodiment, the lead includes a tubular body having a proximal end and a distal end with a lead connector near the proximal end. In this embodiment the lead further includes a conductor extending longitudinally within the tubular body and having a proximal end that is electrically coupled to the connector and a distal end electrically coupled to a contact pin. The lead in this embodiment further includes a filter element electrically coupled to a distal end of the contact pin and a flange electrically coupled between a proximal end of the filter element and a proximal portion of an electrode. In this embodiment the flange and the proximal portion of the electrode form at least a first part of a hermetic chamber enclosing the filter element.

Abstract translation: 本文公开了一种被配置用于改善MRI安全性和加热降低性能的可植入医疗引线。 在一个实施例中，引线包括具有近端和远端的管状体，其具有靠近近端的引线连接器。 在该实施例中，引线还包括在管状体内纵向延伸的导体，并且具有电连接到连接器的近端和电耦合到接触销的远端。 该实施例中的引线还包括电耦合到接触针的远端的过滤元件和电耦合在过滤元件的近端和电极的近端部分之间的凸缘。 在该实施例中，电极的凸缘和近端部分形成封闭过滤元件的密封室的至少第一部分。

公开(公告)号：US20100204767A1

公开(公告)日：2010-08-12

申请号：US12370461

申请日：2009-02-12

Applicant: Yong D. Zhao

Inventor： Yong D. Zhao

IPC: A61N1/05 ,  H01B7/00

CPC classification number: A61N1/05 ,  A61N1/086

Abstract: Implantable medical leads have reduced diameter while providing for optimized mechanical and electrical properties, by reducing the diameters of the conducting cables used within the leads for sensing and delivery of therapeutic electrical stimulation. In an embodiment, conducting filaments within a cable have oval cross-sectional areas. Suitably orienting the oval filaments increases the contact surface between adjacent filaments, broadly distributing the pressure between filaments and reducing fretting fatigue, while the oval cross-sectional area also increases conductivity. In an embodiment, non-conducting coatings around filaments within a cable, or around groups of filaments organized into cable-layers, reduce fretting fatigue. In an embodiment, the cross-sectional area of filaments decreases as the filaments are positioned at increasing radial distances from the center of the cable. In an embodiment, the relative composition of various filament metals and/or alloys is varied in filaments at different radial distances from the center of the cable.

Abstract translation: 可植入的医疗引线通过减小引线内使用的导电电缆的直径来获得最佳的机械和电学性能，减小了直径，用于传感和传递治疗性电刺激。 在一个实施例中，电缆内的导电细丝具有椭圆形横截面。 适当地定向椭圆形长丝增加相邻细丝之间的接触表面，广泛地分布长丝之间的压力并减少微动疲劳，而椭圆形横截面积也增加导电性。 在一个实施例中，电缆周围的细丝周围的非导电涂层或组织成电缆层的细丝组周围的非导电涂层减少了微动疲劳。 在一个实施例中，长丝的横截面积随着电缆的距离中心距离增加的径向距离而减小。 在一个实施例中，各种细丝金属和/或合金的相对组成在长丝中在与电缆中心不同的径向距离处变化。

公开(公告)号：US20100114277A1

公开(公告)日：2010-05-06

申请号：US12262083

申请日：2008-10-30

Applicant: Yong D. Zhao ,  Xiaoyi Min ,  Virote Indravudh

Inventor： Yong D. Zhao ,  Xiaoyi Min ,  Virote Indravudh

IPC: A61N1/05

CPC classification number: A61N1/056 ,  A61N1/086

Abstract: An implantable medical lead is disclosed herein. The lead may include a body and an electrical pathway. The body may include a distal portion with an electrode and a proximal portion with a lead connector end. The electrical pathway may extend between the electrode and lead connector end and may include a coiled inductor including first and second electrically conductive filar cores. The first and second filar cores may be physically joined into a unified single piece proximal terminal on a proximal end of the coiled inductor. The first and second cores may be physically joined into a unified single piece distal terminal on a distal end of the coiled inductor. The first and second filar cores may be helically wound into a coiled portion between the proximal and distal terminals, the filar cores being electrically isolated from each other in the coiled portion. The proximal terminal may be electrically coupled to a portion of the electrical pathway extending to the lead connector end, and the distal terminal may be electrically coupled to a portion of the electrical pathway extending to the electrode.

Abstract translation: 本文公开了可植入医疗引线。 引线可以包括主体和电路径。 主体可以包括具有电极的远端部分和具有引线连接器端部的近端部分。 电路可以在电极和引线连接器端之间延伸并且可以包括包括第一和第二导电丝芯的线圈电感器。 第一和第二丝状芯可以物理地连接到线圈电感器的近端上的统一的单件式近端端子。 第一和第二芯可以物理地连接到线圈电感器的远端上的统一的单件式远端终端。 第一和第二丝芯可以螺旋地缠绕在近端和远端之间的线圈部分中，丝芯在线圈部分中彼此电隔离。 近端端子可以电连接到延伸到引线连接器端的电路径的一部分，并且远端端子可电耦合到延伸到电极的电路径的一部分。

公开(公告)号：US20100049290A1

公开(公告)日：2010-02-25

申请号：US12197957

申请日：2008-08-25

Applicant: Xiaoyi Min ,  J. Christopher Moulder ,  Yong D. Zhao ,  Kevin L. Morgan ,  Martin Cholette ,  Phong D. Doan

Inventor： Xiaoyi Min ,  J. Christopher Moulder ,  Yong D. Zhao ,  Kevin L. Morgan ,  Martin Cholette ,  Phong D. Doan

IPC: A61N1/05

CPC classification number: A61N1/0563 ,  A61N1/086

Abstract: Disclosed herein is an implantable medical lead. In one embodiment, the lead includes a ring electrode, a tip electrode, first and second helically wound coaxial conductor coils, and a distal coil transition. The coils extend between the proximal and distal ends of the lead. The distal coil transition is proximal to the ring electrode and near the distal end and is where the first coil transitions from being outside the second coil proximal of the distal coil transition to being inside the second coil distal of the distal coil transition.

Abstract translation: 本文公开了可植入医疗引线。 在一个实施例中，引线包括环形电极，尖端电极，第一和第二螺旋缠绕的同轴导体线圈和远端线圈转变。 线圈在引线的近端和远端之间延伸。 远侧线圈转变靠近环形电极并且靠近远端，并且是第一线圈从远端线圈过渡处的第二线圈的外侧转变到远端线圈转变远端的第二线圈内部的位置。

公开(公告)号：US08774434B2

公开(公告)日：2014-07-08

申请号：US13286642

申请日：2011-11-01

Applicant: Yong D. Zhao ,  Jennifer Jinping Zhao

Inventor： Yong D. Zhao ,  Jennifer Jinping Zhao

IPC: H04R25/00

CPC classification number: H04R25/656 ,  H04R25/658 ,  H04R2225/025

Abstract: An in-ear hearing aid device that provides users with a customizable ear piece to fit the ear canal of any user. More specifically, the present invention can comprises of a hard case to hold all the electronics of the device with a hearing device jacket that envelops the device. An ear mold is connected to the jacket and allows the user to insert the device into the ear canal to enhance the user's hearing.

Abstract translation: 入耳式助听器装置，为用户提供可定制的耳塞，以适应任何用户的耳道。 更具体地说，本发明可以包括一个硬壳，用来容纳该设备的所有电子设备，其中一个听觉装置夹套包围该设备。 耳模连接到护套，并允许使用者将装置插入耳道中以增强使用者的听力。

公开(公告)号：US20100114276A1

公开(公告)日：2010-05-06

申请号：US12262047

申请日：2008-10-30

Applicant: Xiaoyi Min ,  J. Christopher Moulder ,  Yong D. Zhao ,  Virote Indravudh ,  Ingmar Viohl

Inventor： Xiaoyi Min ,  J. Christopher Moulder ,  Yong D. Zhao ,  Virote Indravudh ,  Ingmar Viohl

IPC: A61N1/05

CPC classification number: A61N1/05 ,  A61N1/086 ,  H01F17/00

Abstract: An implantable medical lead is disclosed herein. In one embodiment, the lead includes a body and an electrical pathway. The body may include a distal portion with an electrode and a proximal portion with a lead connector end. The electrical pathway may extend between the electrode and lead connector end and include a coiled inductor including a first portion and a second portion at least partially magnetically decoupled from the first portion. The first portion may include a first configuration having a first SRF. The second portion may include a second configuration different from the first configuration. The second configuration may have a second SRF different from the first SRF. For example, the first SRF may be near 64 MHz and the second SRF may be near 128 MHz.

Abstract translation: 本文公开了可植入医疗引线。 在一个实施例中，引线包括主体和电路径。 主体可以包括具有电极的远端部分和具有引线连接器端部的近端部分。 电路可以在电极和引线连接器端之间延伸，并且包括线圈电感器，其包括至少部分地与第一部分磁耦合的第一部分和第二部分。 第一部分可以包括具有第一SRF的第一配置。 第二部分可以包括不同于第一配置的第二配置。 第二配置可以具有与第一SRF不同的第二SRF。 例如，第一SRF可以接近64MHz，而第二SRF可以接近128MHz。