公开(公告)号：US08815243B2

公开(公告)日：2014-08-26

申请号：US13817760

申请日：2011-08-18

Applicant: Yoon Jin Lee ,  Yun-Sil Lee ,  Hae-June Lee ,  Seo-Hyun Choi ,  Kyeng-Jung Kim

Inventor： Yoon Jin Lee ,  Yun-Sil Lee ,  Hae-June Lee ,  Seo-Hyun Choi ,  Kyeng-Jung Kim

IPC: C07K16/18 ,  C07K14/435 ,  C07K16/44 ,  A61K39/395

CPC classification number: A61K39/3955 ,  A61K39/395 ,  A61K2039/505 ,  C07K16/18 ,  C07K2317/76

Abstract: The present invention relates to a pharmaceutical composition for promoting angiogenesis, containing an antibody that specifically binds to heat shock protein (HSP) 27. In addition, the present invention relates to a pharmaceutical composition containing an antibody that specifically binds to HSP 27, for treating an angiogenesis-dependent ailment selected from a group consisting of a wound, chronic ulcer, ischemic stroke, myocardial infarction, angina pectoris, and cerebrovascular dementia. In addition, the present invention relates to a method for promoting the in vitro growth of endothelial cells using an antibody that specifically binds to HSP27. In addition, the present invention relates to a method for screening for active substances for promoting angiogenesis or for active substances for treating an angiogenesis-dependent ailment, the method comprising the following steps: treating vascular endothelial cell lines with each specimen; measuring the content of HSP27 in the respective vascular endothelial cell lines; and selecting a specimen in which the HSP27 content in the vascular endothelial cell lines are decreased as compared to a control group.

Abstract translation: 本发明涉及用于促进血管生成的药物组合物，其含有与热休克蛋白（HSP）27特异性结合的抗体。此外，本发明涉及含有与HSP27特异性结合的抗体的药物组合物，用于治疗 选自伤口，慢性溃疡，缺血性中风，心肌梗死，心绞痛和脑血管性痴呆的血管发生依赖性疾病。 此外，本发明涉及使用特异性结合HSP27的抗体促进内皮细胞体外生长的方法。 此外，本发明涉及一种筛选用于促进血管发生的活性物质的方法或用于治疗血管生成依赖性疾病的活性物质的方法，所述方法包括以下步骤：用每个样品处理血管内皮细胞系; 测量各血管内皮细胞系中HSP27的含量; 并且与对照组相比，选择其中血管内皮细胞系中HSP27含量降低的标本。

公开(公告)号：US08406310B2

公开(公告)日：2013-03-26

申请号：US11623157

申请日：2007-01-15

Applicant: Gwang-Hoon Park ,  Chie-Teuk Ahn ,  Won-Sik Cheong ,  Jin-Woong Kim ,  Kyu-Heon Kim ,  Myoung-Ho Lee ,  Yoon-Jin Lee ,  Young-Kwon Lim

Inventor： Gwang-Hoon Park ,  Chie-Teuk Ahn ,  Won-Sik Cheong ,  Jin-Woong Kim ,  Kyu-Heon Kim ,  Myoung-Ho Lee ,  Yoon-Jin Lee ,  Young-Kwon Lim

IPC: H04N7/18

CPC classification number: H04N19/34 ,  H04N19/129 ,  H04N19/17 ,  H04N19/184 ,  H04N19/187 ,  H04N19/29 ,  H04N19/61

Abstract: A water ring encoding method of processing an initial data set, such as an image frame, is disclosed having a writing step and an encoding step. The initial data set is organized with at least one initial origin enveloped by a plurality of nested initial environs successively surrounding each other in the initial data set. The writing step includes writing a portion of data from the initial data set into a scanned data string, by starting the writing of the portion of the data from the initial data set into the scanned data string at the RC grouping corresponding to the initial origin (initial water ring (0)) and by sequentially progressing the writing outwardly from the family of RC groupings corresponding to the nearest nested initial environ (initial water ring (1)) towards the family of RC groupings corresponding to a furthest nested initial environ (initial water ring (n)). The encoding step includes encoding the scanned data string into an encoded data string.

Abstract translation: 公开了一种处理诸如图像帧的初始数据集的水环编码方法，其具有写入步骤和编码步骤。 初始数据集由至少一个由初始数据集中相互围绕的多个嵌套初始环境包围的初始原点组织。 写入步骤包括通过开始将数据的一部分从初始数据集写入扫描数据串中，以对应于初始原点的RC分组将初始数据集的一部分数据写入扫描数据串中 初始水环（0）），并且从对应于最近的嵌套初始环境（初始水环（1））的RC组的一系列顺序地向相对于最远嵌套初始环境（初始水环（0））的RC组的族 水环（n））。 编码步骤包括将扫描数据串编码成编码数据串。

公开(公告)号：US08184718B2

公开(公告)日：2012-05-22

申请号：US11623159

申请日：2007-01-15

Applicant: Gwang-Hoon Park ,  Chie-Teuk Ahn ,  Won-Sik Cheong ,  Jin-Woong Kim ,  Kyu-Heon Kim ,  Myoung-Ho Lee ,  Yoon-Jin Lee ,  Young-Kwon Lim

Inventor： Gwang-Hoon Park ,  Chie-Teuk Ahn ,  Won-Sik Cheong ,  Jin-Woong Kim ,  Kyu-Heon Kim ,  Myoung-Ho Lee ,  Yoon-Jin Lee ,  Young-Kwon Lim

IPC: H04N11/04 ,  H04N11/02

CPC classification number: H04N19/34 ,  H04N19/129 ,  H04N19/17 ,  H04N19/184 ,  H04N19/187 ,  H04N19/29 ,  H04N19/61

Abstract: A water ring decoding apparatus configured to process a data string into a restored data set, such as a video image frame, is disclosed. The restored data set is organized with at least one restored origin enveloped by a plurality of nested restored environs successively surrounding each other in the restored data set. The decoder is configured to write the data string into the restored data set by starting at the RC group corresponding to the restored origin (restored water ring (0)) and by sequentially progressing outwardly from the family of RC groups corresponding to the nearest nested restored environ (restored water ring (1)) towards the family of RC groups corresponding to a furthest nested restored environ (restored water ring (n)).

Abstract translation: 公开了一种水环解码装置，被配置为将数据串处理成诸如视频帧的恢复数据集。 恢复的数据集由至少一个由恢复的数据集中相互围绕的多个嵌套的恢复环境包围的恢复原点组织。 解码器被配置为通过从对应于恢复的原点（恢复的水环（0））的RC组开始将数据串写入恢复的数据集，并且从对应于最近的嵌套恢复的RC组的系列向外顺序地向前 环境（恢复水环（1））朝向对应于最远嵌套的恢复环境（恢复水环（n））的RC组的系列。

公开(公告)号：US20070121732A1

公开(公告)日：2007-05-31

申请号：US11623131

申请日：2007-01-15

Applicant: Gwang-Hoon PARK ,  Chie-Teuk AHN ,  Won-Sik CHEONG ,  Jin-Woong KIM ,  Kyu-Heon KIM ,  Myoung-Ho LEE ,  Yoon-Jin LEE ,  Young-Kwon LIM

Inventor： Gwang-Hoon PARK ,  Chie-Teuk AHN ,  Won-Sik CHEONG ,  Jin-Woong KIM ,  Kyu-Heon KIM ,  Myoung-Ho LEE ,  Yoon-Jin LEE ,  Young-Kwon LIM

IPC: H04N11/04 ,  H04N7/12

CPC classification number: H04N19/34 ,  H04N19/129 ,  H04N19/17 ,  H04N19/184 ,  H04N19/187 ,  H04N19/29 ,  H04N19/61

Abstract: A water ring scanning apparatus configured to process an initial data set, such as a video frame, is disclosed. The water ring scanning apparatus is configured to write a portion of data from the initial data set into a data string. The initial data set is organized with at least one initial origin enveloped by a plurality of nested initial environs successively surrounding each other in the initial data set. The scanner is configured to write a portion of the data from the initial data set into the data string by starting at the RC grouping corresponding to the initial origin (initial water ring (0)) and by sequentially progressing outwardly from the family of RC groupings corresponding to the nearest nested initial environ (initial water ring (1)) towards the family of RC groupings corresponding to a furthest nested initial environ (initial water ring (n)).

Abstract translation: 公开了一种被配置为处理诸如视频帧之类的初始数据集的水环扫描装置。 水环扫描装置被配置为将来自初始数据集的数据的一部分写入数据串。 初始数据集由至少一个由初始数据集中相互围绕的多个嵌套初始环境包围的初始原点组织。 扫描器被配置为通过从对应于初始原点（初始水环（0））的RC分组开始并且从RC组的系列向外顺序地将来自初始数据集的数据的一部分写入数据串 对应于对应于最远嵌套初始环境（初始水环（n））的RC组的最近的嵌套初始环境（初始水环（1））。

公开(公告)号：US20050013357A1

公开(公告)日：2005-01-20

申请号：US10496927

申请日：2002-11-26

Applicant: Won-Sik Cheong ,  Kyuheon Kim ,  Yoon-Jin Lee ,  Jinwoong Kim ,  Chieteuk Ahn ,  Gwang-Hoon Park

Inventor： Won-Sik Cheong ,  Kyuheon Kim ,  Yoon-Jin Lee ,  Jinwoong Kim ,  Chieteuk Ahn ,  Gwang-Hoon Park

IPC: H04N19/102 ,  H04N7/12 ,  H04N7/24 ,  H04N19/167 ,  H04N19/172 ,  H04N19/189 ,  H04N19/196 ,  H04N19/34 ,  H04N19/503 ,  H04N19/61 ,  H04N19/625 ,  H04N19/70 ,  H04N19/85 ,  H04N19/91

CPC classification number: H04N19/34 ,  H04N19/112 ,  H04N19/126 ,  H04N19/129 ,  H04N19/154 ,  H04N19/176 ,  H04N19/184 ,  H04N19/46 ,  H04N19/61

Abstract: Provided are intelligent water ring scan apparatus and method thereof, image encoding/decoding apparatus using the water ring scanning and method thereof, and a computer-readable recording medium for recording a program that implements the methods. The apparatus or method of this research selectively improves the image quality of a particular image part that needs to be encoded with priority by transmitting the image data of the particular image part suitably for a human visual system so as to provide a visually improved image. The encoding apparatus of this research differentiates the amount of image data depending on the significance of a certain image part to process the image in various qualities suitably for the human visual system. The methods of this research can be applied to an image encoding/decoding process.

Abstract translation: 提供了智能水环扫描装置及其方法，使用水环扫描的图像编码/解码装置及其方法，以及用于记录实现方法的程序的计算机可读记录介质。 该研究的装置或方法通过适当地为人类视觉系统发送特定图像部分的图像数据来选择性地提高需要优先编码的特定图像部分的图像质量，以提供视觉上改善的图像。 本研究的编码装置根据某些图像部分的重要性来区分图像数据的量，以适当地为人类视觉系统处理各种品质的图像。 本研究的方法可以应用于图像编码/解码过程。

公开(公告)号：US09149505B2

公开(公告)日：2015-10-06

申请号：US13817738

申请日：2011-08-18

Applicant: Yoon Jin Lee ,  Yun-Sil Lee ,  Hae-June Lee ,  Seo-Hyun Choi ,  Kyeng-Jung Kim

Inventor： Yoon Jin Lee ,  Yun-Sil Lee ,  Hae-June Lee ,  Seo-Hyun Choi ,  Kyeng-Jung Kim

IPC: A61K38/17 ,  G01N33/574 ,  C07K16/18 ,  A61K48/00

CPC classification number: A61K38/1709 ,  A61K48/00 ,  C07K16/18 ,  C07K2317/76 ,  G01N33/57407 ,  G01N33/57484

Abstract: The present invention provides a pharmaceutical composition for suppressing angiogenesis, containing heat shock protein 27 (HSP27) or a nucleic acid encoding HSP27. In addition, the present invention provides a pharmaceutical composition for treating cancer, containing HSP27 or a nucleic acid encoding HSP27. Additionally, the present invention provides a method of suppressing the in vitro growth of endothelial cells using HSP27. Further, the present invention provides a method of screening an active material for suppressing angiogenesis or an active material for treating cancer, comprising the following steps: processing endothelial cell lines into samples, respectively; measuring the content of HSP27 in an endothelial cell line; and selecting the sample in which the content of HSP27 in an endothelial cell line is increased compared with a control group.

Abstract translation: 本发明提供了含有热休克蛋白27（HSP27）或编码HSP27的核酸的血管生成抑制药物组合物。 此外，本发明提供了含有HSP27或编码HSP27的核酸的治疗癌症的药物组合物。 此外，本发明提供了使用HSP27抑制内皮细胞的体外生长的方法。 此外，本发明提供了筛选用于抑制血管生成的活性物质或用于治疗癌症的活性物质的方法，包括以下步骤：分别将内皮细胞系分别加工成样品; 测量内皮细胞系中HSP27的含量; 并且与对照组相比，选择其中内皮细胞系中HSP27的含量增加的样品。

公开(公告)号：US08786593B2

公开(公告)日：2014-07-22

申请号：US12135274

申请日：2008-06-09

Applicant: Do-Young Joung ,  Tae-Sung Park ,  Yun-Je Oh ,  Doug-Young Suh ,  Gwang-Hoon Park ,  Kyu-Heon Kim ,  Yoon-Jin Lee

Inventor： Do-Young Joung ,  Tae-Sung Park ,  Yun-Je Oh ,  Doug-Young Suh ,  Gwang-Hoon Park ,  Kyu-Heon Kim ,  Yoon-Jin Lee

IPC: G06T15/00

CPC classification number: G11B27/10 ,  H04N13/178 ,  H04N13/189 ,  H04N19/597 ,  H04N21/23412 ,  H04N21/4334 ,  H04N21/44012 ,  H04N21/4402 ,  H04N21/8146 ,  H04N21/84 ,  H04N21/85406

Abstract: Disclosed is a method of storing scene comprising a three-dimensional image, which has been generated by converting an image input an apparatus supporting photographing of the three-dimensional image, into a recording medium. The method includes: loading, in a predetermined file type field, image type information indicating one of a single stereoscopic image and a synthetic image including a monoscopic image and a stereoscopic image; loading, in a configurative information container field, scene descriptor information indicating temporal and spatial relations between a plurality of media objects included in the three-dimensional image, object configurative information indicating object attributes of each media object of said plurality of media objects and a configurative relation between encoded streams of each of the media objects of said plurality, configurative information of the encoded streams, first metadata between the plurality of media objects, and second metadata between each media object of the plurality and the encoded stream thereof, and loading, in a media data container field, a bit stream of each media object included in the three-dimensional image, a bit stream for the first metadata, and a bit stream for the second metadata.

Abstract translation: 公开了一种存储场景的方法，该场景包括通过将支持三维图像拍摄的设备的图像输入转换成记录介质而产生的三维图像。 该方法包括：在预定文件类型字段中加载指示单个立体图像和包括单视场图像和立体图像的合成图像之一的图像类型信息; 在配置信息容器字段中加载指示包括在三维图像中的多个媒体对象之间的时间和空间关系的场景描述符信息，指示所述多个媒体对象中的每个媒体对象的对象属性的对象配置信息和配置信息 所述多个媒体对象的编码流之间的关系，编码流的配置信息，多个媒体对象之间的第一元数据以及多个媒体对象之间的第二元数据及其编码流之间的关系，以及 媒体数据容器字段，包括在三维图像中的每个媒体对象的比特流，用于第一元数据的比特流和用于第二元数据的比特流。

公开(公告)号：US20130156787A1

公开(公告)日：2013-06-20

申请号：US13817760

申请日：2011-08-18

Applicant: Yoon Jin Lee ,  Yun-Sil Lee ,  Hae-June Lee ,  Seo-Hyun Choi ,  Kyeng-Jung Kim

Inventor： Yoon Jin Lee ,  Yun-Sil Lee ,  Hae-June Lee ,  Seo-Hyun Choi ,  Kyeng-Jung Kim

IPC: A61K39/395

CPC classification number: A61K39/3955 ,  A61K39/395 ,  A61K2039/505 ,  C07K16/18 ,  C07K2317/76

Abstract: The present invention relates to a pharmaceutical composition for promoting angiogenesis, containing an antibody that specifically binds to heat shock protein (HSP) 27. In addition, the present invention relates to a pharmaceutical composition containing an antibody that specifically binds to HSP 27, for treating an angiogenesis-dependent ailment selected from a group consisting of a wound, chronic ulcer, ischemic stroke, myocardial infarction, angina pectoris, and cerebrovascular dementia. In addition, the present invention relates to a method for promoting the in vitro growth of endothelial cells using an antibody that specifically binds to HSP27. In addition, the present invention relates to a method for screening for active substances for promoting angiogenesis or for active substances for treating an angiogenesis-dependent ailment, the method comprising the following steps: treating vascular endothelial cell lines with each specimen; measuring the content of HSP27 in the respective vascular endothelial cell lines; and selecting a specimen in which the HSP27 content in the vascular endothelial cell lines are decreased as compared to a control group.

Abstract translation: 本发明涉及用于促进血管生成的药物组合物，其含有与热休克蛋白（HSP）27特异性结合的抗体。此外，本发明涉及含有与HSP27特异性结合的抗体的药物组合物，用于治疗 选自伤口，慢性溃疡，缺血性中风，心肌梗死，心绞痛和脑血管性痴呆的血管发生依赖性疾病。 此外，本发明涉及使用特异性结合HSP27的抗体促进内皮细胞体外生长的方法。 此外，本发明涉及一种筛选用于促进血管发生的活性物质的方法或用于治疗血管生成依赖性疾病的活性物质的方法，所述方法包括以下步骤：用每个样品处理血管内皮细胞系; 测量各血管内皮细胞系中HSP27的含量; 并且与对照组相比，选择其中血管内皮细胞系中HSP27含量降低的标本。

公开(公告)号：US08184719B2

公开(公告)日：2012-05-22

申请号：US11623163

申请日：2007-01-15

Applicant: Gwang-Hoon Park ,  Chie-Teuk Ahn ,  Won-Sik Cheong ,  Jin-Woong Kim ,  Kyu-Heon Kim ,  Myoung-Ho Lee ,  Yoon-Jin Lee ,  Young-Kwon Lim

Inventor： Gwang-Hoon Park ,  Chie-Teuk Ahn ,  Won-Sik Cheong ,  Jin-Woong Kim ,  Kyu-Heon Kim ,  Myoung-Ho Lee ,  Yoon-Jin Lee ,  Young-Kwon Lim

IPC: H04N11/04

CPC classification number: H04N19/34 ,  H04N19/129 ,  H04N19/17 ,  H04N19/184 ,  H04N19/187 ,  H04N19/29 ,  H04N19/61

Abstract: A water ring decoding method of processing a data string into a restored data set, such as a video image frame, is disclosed. The restored data set is organized with at least one restored origin enveloped by a plurality of nested restored environs successively surrounding each other in the restored data set. The water ring decoding method includes the steps of decoding by writing the data string into the restored data set by starting at the RC group corresponding to the restored origin (restored water ring (0)) and by sequentially progressing outwardly from the family of RC groups corresponding to the nearest nested restored environ (restored water ring (1)) towards the family of RC groups corresponding to a furthest nested restored environ (restored water ring (n)).

Abstract translation: 公开了一种将数据串处理成诸如视频帧的恢复数据集的水环解码方法。 恢复的数据集由至少一个由恢复的数据集中相互围绕的多个嵌套的恢复环境包围的恢复原点组织。 水环解码方法包括以下步骤：通过从对应于恢复的原点（恢复水环（0））的RC组开始将数据串写入恢复的数据集，并且从RC组的系列向外顺序地进行解码 对应于最近嵌套的恢复环境（恢复水环（1））朝向对应于最远嵌套的恢复环境（恢复水环（n））的RC组的系列。

公开(公告)号：US07388916B2

公开(公告)日：2008-06-17

申请号：US10332205

申请日：2001-07-07

Applicant: Gwang-Hoon Park ,  Chie-Teuk Ahn ,  Won-Sik Cheong ,  Jin-Woong Kim ,  Kyu-Heon Kim ,  Myoung-Ho Lee ,  Yoon-Jin Lee ,  Young-Kwon Lim

Inventor： Gwang-Hoon Park ,  Chie-Teuk Ahn ,  Won-Sik Cheong ,  Jin-Woong Kim ,  Kyu-Heon Kim ,  Myoung-Ho Lee ,  Yoon-Jin Lee ,  Young-Kwon Lim

IPC: H04N7/18

CPC classification number: H04N19/34 ,  H04N19/129 ,  H04N19/17 ,  H04N19/184 ,  H04N19/187 ,  H04N19/29 ,  H04N19/61

Abstract: A water ring scanning apparatus and method, and an apparatus and method for encoding/decoding video sequences using the same are disclosed. A water ring scanning apparatus includes: a preferential scan unit for scanning information on a water ring origin point (water_ring(0)) in an image frame, which is a most significant bit of the image frame to be preferentially scanned; a scan location decision unit for deciding a location of i_th generated water ring (water_ring(i)), which is a rectangular-shape ring surrounding the water ring origin point; and a scan unit for scanning information on the location of the i_th generated water ring.

Abstract translation: 公开了一种水环扫描装置和方法，以及使用其编码/解码视频序列的装置和方法。 水环扫描装置包括：优先扫描单元，用于扫描作为要被优先扫描的图像帧的最高有效位的图像帧中的水环原点（water_ring（0））上的信息; 扫描位置决定单元，用于决定围绕水环原点的矩形环的第i个生成的水环（water_ring（i））的位置; 以及扫描单元，用于扫描关于第i个生成的水环的位置的信息。