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公开(公告)号：US09867728B2
公开(公告)日：2018-01-16
申请号：US14881073
申请日：2015-10-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , Michael H. Ngo , Boris Anukhin , Alexander Nikanorov , Syed Hossainy , John E. Papp , Dudley Jayasinghe , Zella Solter
IPC: A61F2/958 , A61F2/915 , B29C35/08 , A61F2/844 , A61F2/91 , A61L27/00 , A61L31/06 , A61F2/86 , A61L31/14 , A61F2/89 , A61F2/82 , A61F2/95 , B29K67/00 , B29L23/00 , B29L31/00
CPC classification number: A61F2/958 , A61F2/82 , A61F2/844 , A61F2/86 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/9522 , A61F2210/0004 , A61F2210/0014 , A61F2210/0019 , A61F2210/0076 , A61F2230/0006 , A61F2230/0008 , A61F2250/0067 , A61F2250/0096 , A61F2250/0098 , A61L27/00 , A61L31/06 , A61L31/14 , B21D39/046 , B29C35/08 , B29C2035/0838 , B29K2067/046 , B29L2023/00 , B29L2031/7543 , Y10T29/49826 , Y10T29/4987 , Y10T29/49908 , Y10T29/49925 , Y10T29/49927 , C08L67/04 , C08L71/02
Abstract: A method of manufacturing a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures. The crimped profile of the stent of the present invention can be as small as the crimped profile of a same stent but without the marker support structures.
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公开(公告)号：US09770351B2
公开(公告)日：2017-09-26
申请号：US14042512
申请日：2013-09-30
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , Michael H. Ngo , Boris Anukhin , Alexander Nikanorov , Syed Hossainy , John E. Papp , Dudley Jayasinghe , Zella Solter
IPC: A61F2/82 , A61F2/958 , A61F2/91 , A61L27/00 , A61L31/06 , A61F2/86 , A61F2/844 , B29C35/08 , A61L31/14 , A61F2/89 , A61F2/915 , A61F2/95 , B29K67/00 , B29L23/00 , B29L31/00
CPC classification number: A61F2/958 , A61F2/82 , A61F2/844 , A61F2/86 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/9522 , A61F2210/0004 , A61F2210/0014 , A61F2210/0019 , A61F2210/0076 , A61F2230/0006 , A61F2230/0008 , A61F2250/0067 , A61F2250/0096 , A61F2250/0098 , A61L27/00 , A61L31/06 , A61L31/14 , B21D39/046 , B29C35/08 , B29C2035/0838 , B29K2067/046 , B29L2023/00 , B29L2031/7543 , Y10T29/49826 , Y10T29/4987 , Y10T29/49908 , Y10T29/49925 , Y10T29/49927 , C08L67/04 , C08L71/02
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold has a pattern including an asymmetric closed cell connecting links connecting the closed cells.
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公开(公告)号：US20160175044A1
公开(公告)日：2016-06-23
申请号：US14992379
申请日：2016-01-11
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Chad Abunassar , John Stankus , Jesus Magana , David Mackiewicz , Mikael Trollsas , Syed Hossainy , Scott Perrin
CPC classification number: A61B18/1492 , A61B2018/0016 , A61B2018/00214 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/1435 , A61B2018/1467 , A61F7/12 , A61N1/403
Abstract: A catheter apparatus for treatment of a human patient is described, the catheter apparatus having a central axis and comprising a shaping structure moveable between a delivery state having a first helical shape, and a deployed state having a second helical shape. The shaping structure is configured to have a reverse taper with a structural diameter that varies over the length of the shaping structure such that the structural diameter of the shaping structure at the proximal end is smaller than the structural diameter of the shaping structure at the distal end.
Abstract translation: 描述了用于治疗人类患者的导管装置，所述导管装置具有中心轴线，并且包括可在具有第一螺旋形状的输送状态和具有第二螺旋形状的展开状态之间移动的成形结构。 成型结构被配置为具有在成形结构的长度上变化的结构直径的倒锥形，使得近端处的成形结构的结构直径小于远端处的成形结构的结构直径 。
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24.发明申请METHOD OF TREATMENT WITH A BIOABSORBABLE STENT WITH TIME DEPENDENT STRUCTURE AND PROPERTIES AND REGIO-SELECTIVE DEGRADATION 审中-公开用具有时间依赖性结构和性质的生物可降解的固体处理方法和选择性降解公开(公告)号：US20150182360A1
公开(公告)日：2015-07-02
申请号：US14656553
申请日：2015-03-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , Dariush Davalian , Michael Huy Ngo , Hao-Ming Hsiao , Boris Anukhin , Syed Hossainy , David Gale
IPC: A61F2/89
CPC classification number: A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/828 , A61F2210/0004 , A61F2230/0054 , A61F2250/0036 , A61L31/06 , A61L31/10 , A61L31/148 , C08L67/04
Abstract: A bioabsorbable polymeric stent with time dependent structure and properties and methods of treating a diseased blood vessel with the bioabsorable polymeric stent are disclosed. The structure and properties of the stent change with time and allow the vessel to be restored to a natural unstented state. The bioabsorbable stent loses mechanical integrity in a controlled manner due to modification of selected structural elements.
Abstract translation: 公开了具有时间依赖性结构的生物可吸收聚合物支架，以及用生物可吸收聚合物支架治疗患病血管的特性和方法。 支架的结构和性质随时间而变化，并允许血管恢复到自然不稳定状态。 由于选择的结构元件的修饰，生物可吸收的支架以受控的方式失去机械完整性。
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公开(公告)号：US20150010491A1
公开(公告)日：2015-01-08
申请号：US14493197
申请日：2014-09-22
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Lothar W. Kleiner , Syed Hossainy , Stephen Pacetti , Jessica DesNoyer
IPC: A61K47/48 , A61K31/727
CPC classification number: A61K47/48207 , A61K9/0024 , A61K9/08 , A61K9/10 , A61K31/337 , A61K31/4745 , A61K31/727 , A61K47/34 , A61K47/593 , A61K47/595 , A61K47/60 , C08L77/12 , C08L2205/02 , C08L2666/20
Abstract: A therapeutic agent delivery system formed of a specific type of poly(ester amide) (PEA), a therapeutic agent, and a water miscible solvent is described herein. A method of delivering the therapeutic agent delivery system by delivering the therapeutic agent delivery system formed of a PEA polymer, a therapeutic agent, and a water miscible solvent to a physiological environment and separating the phase of the therapeutic agent delivery system to form a membrane from the polymer to contain the therapeutic agent within the physiological environment is also described. Additionally disclosed is a kit including a syringe and a therapeutic agent delivery system within the syringe.
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Patent Agency Ranking
公开(公告)号：US20140330363A1
公开(公告)日：2014-11-06
申请号：US14323992
申请日：2014-07-03
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Boris Anukhin , Michael H. Ngo , Mikael Trollsas , Syed Hossainy , John Papp
IPC: A61F2/89
CPC classification number: A61F2/89 , A61F2/82 , A61F2/915 , A61F2002/91508 , A61F2002/91575 , A61F2240/002 , A61M25/1034 , B23P11/005 , B29C55/24 , B29C69/00 , Y10T29/49908
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold also has a reduced crimped profile and a modification of the scaffold's ring structure at the crowns that contributes to the reduced crimped profile.
Abstract translation: 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。 支架在被气囊部署之后，在支架的直径被挤压或压碎50％后，提供约90％的压碎回收率。 支架还具有减小的卷边轮廓和在冠部处的支架环形结构的改进，其有助于减小卷曲轮廓。
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公开(公告)号：US20140276747A1
公开(公告)日：2014-09-18
申请号：US13842277
申请日：2013-03-15
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Chad Abunassar , John Stankus , Jesus Magana , David Mackiewicz , Mikael Trollsas , Syed Hossainy , Scott Perrin
CPC classification number: A61B18/1492 , A61B2018/0016 , A61B2018/00214 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/1435 , A61B2018/1467 , A61F7/12 , A61N1/403
Abstract: A catheter apparatus for treatment of a human patient is described, the catheter apparatus having a central axis and comprising a shaping structure moveable between a delivery state having a first helical shape, and a deployed state having a second helical shape. The shaping structure is configured to have a reverse taper with a structural diameter that varies over the length of the shaping structure such that the structural diameter of the shaping structure at the proximal end is smaller than the structural diameter of the shaping structure at the distal end.
Abstract translation: 描述了用于治疗人类患者的导管装置，所述导管装置具有中心轴线，并且包括可在具有第一螺旋形状的输送状态和具有第二螺旋形状的展开状态之间移动的成形结构。 成型结构被配置为具有在成形结构的长度上变化的结构直径的倒锥形，使得近端处的成形结构的结构直径小于远端处的成形结构的结构直径 。
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公开(公告)号：US20140276360A1
公开(公告)日：2014-09-18
申请号：US13843082
申请日：2013-03-15
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Stephen D. Pacetti , Dariush Davalian , John Stankus , Mikael Trollsas , Syed Hossainy , Michael Ngo
IPC: A61N1/30
CPC classification number: A61N1/306
Abstract: Balloon catheter configured to deliver a therapeutic agent upon provision of electric potential to the balloon, the catheter comprising an electrode disposed proximate the outer surface of the expandable member, a coating disposed on at least a portion of the outer surface, the coating including a therapeutic agent; and a power source in electrical communication with the electrode is described.
Abstract translation: 球囊导管，其构造成在向气囊提供电位时递送治疗剂，所述导管包括邻近所述可扩张构件的外表面设置的电极，设置在所述外表面的至少一部分上的涂层，所述涂层包括治疗 代理人 并描述与电极电连通的电源。
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公开(公告)号：US20140120053A1
公开(公告)日：2014-05-01
申请号：US14149533
申请日：2014-01-07
Applicant: Abbott Cardiovascular Systems Inc
Inventor： Lothar W. Kleiner , Syed Hossainy , Stephen Pacetti , Jessica DesNoyer
IPC: A61K47/48
CPC classification number: A61K47/48207 , A61K9/0024 , A61K9/08 , A61K9/10 , A61K31/337 , A61K31/4745 , A61K31/727 , A61K47/34 , A61K47/593 , A61K47/595 , A61K47/60 , C08L77/12 , C08L2205/02 , C08L2666/20
Abstract: A therapeutic agent delivery system formed of a specific type of poly(ester amide) (PEA), a therapeutic agent, and a water miscible solvent is described herein. A method of delivering the therapeutic agent delivery system by delivering the therapeutic agent delivery system formed of a PEA polymer, a therapeutic agent, and a water miscible solvent to a physiological environment and separating the phase of the therapeutic agent delivery system to form a membrane from the polymer to contain the therapeutic agent within the physiological environment is also described. Additionally disclosed is a kit including a syringe and a therapeutic agent delivery system within the syringe.
Abstract translation: 本文描述了由特定类型的聚（酯酰胺）（PEA），治疗剂和水混溶性溶剂形成的治疗剂递送系统。 通过将由PEA聚合物，治疗剂和水混溶性溶剂形成的治疗剂递送系统递送到生理环境来递送治疗剂递送系统的方法，并分离治疗剂递送系统的相以形成膜 还描述了在生理环境中含有治疗剂的聚合物。 另外公开了一种试剂盒，其包括注射器内的注射器和治疗剂递送系统。
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公开(公告)号：US20140025005A1
公开(公告)日：2014-01-23
申请号：US13911962
申请日：2013-06-06
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： John J. Stankus , Mikael Trollsas , Syed Hossainy
IPC: A61L29/08
CPC classification number: A61L29/085 , A61L29/16 , A61L2300/416 , A61L2300/608 , A61L2300/61
Abstract: A drug delivery balloon is provided, the a balloon having an outer surface, and a tunable coating disposed on at least a length of the balloon surface. The tunable coating includes a first therapeutic agent and a first excipient, and a second therapeutic agent and a second excipient. The first and second therapeutic agents have different dissolution rates during balloon inflation and therefore provide a coating that is tunable.
Abstract translation: 提供药物递送球囊，具有外表面的气囊和设置在球囊表面的至少一段长度上的可调涂层。 可调涂层包括第一治疗剂和第一赋形剂，以及第二治疗剂和第二赋形剂。 第一和第二治疗剂在球囊膨胀期间具有不同的溶解速率，因此提供可调谐的涂层。
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