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公开(公告)号：US20240390682A1
公开(公告)日：2024-11-28
申请号：US18609736
申请日：2024-03-19
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Simeng Zhang , Hyun-Joo Park , Filippo Agnesi , Yagna Pathak , Erika Ross
Abstract: The present disclosure provides systems and methods for generating burst waveforms. An implantable neurostimulation system includes an implantable stimulation lead including a plurality of contacts, and an implantable pulse generator communicatively coupled to the stimulation lead. The pulse generator is configured to generate a waveform including a burst that includes a leading anodic pulse followed by alternating cathodic pulses and anodic pulses, each cathodic pulse in the burst having a greater amplitude than the previous cathodic pulse.
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公开(公告)号：US12102826B2
公开(公告)日：2024-10-01
申请号：US17082318
申请日：2020-10-28
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Hyun-Joo Park , Simeng Zhang , Yagna Pathak , Erika Ross
CPC classification number: A61N1/36125 , A61N1/025 , A61N1/36192 , A61N1/36196 , G16H20/30 , A61N1/0534 , A61N1/0551 , A61N1/3616
Abstract: The present disclosure provides systems and methods for generating pulsed waveforms that approximate colored noise for use in a neurostimulation system. An implantable neurostimulation system includes an implantable stimulation lead including a plurality of contacts, and an implantable pulse generator communicatively coupled to the stimulation lead. The pulse generator is configured to generate a pulsed waveform that approximates colored noise using at least one of a thresholding method and an optimization method, and cause stimulation to be delivered by the stimulation lead based on the pulsed waveform.
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公开(公告)号：US11786309B2
公开(公告)日：2023-10-17
申请号：US17135022
申请日：2020-12-28
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor： Yagna Pathak , Simeng Zhang , Dehan Zhu , Anahita Kyani , Hyun-Joo Park , Erika Ross
IPC: A61B34/10 , G06T7/70 , G16H30/40 , G06V10/25 , A61B5/055 , A61B6/03 , A61B6/00 , G06N3/08 , G06T7/00 , G06F18/214 , A61N1/05
CPC classification number: A61B34/10 , A61B5/055 , A61B6/032 , A61B6/469 , A61B6/501 , A61B6/5223 , A61B6/5247 , G06F18/214 , G06N3/08 , G06T7/0014 , G06T7/70 , G06V10/25 , G16H30/40 , A61B2034/107 , A61B2505/05 , A61N1/0534 , G06T2207/10081 , G06T2207/10088 , G06T2207/20081 , G06T2207/20084 , G06T2207/30016 , G06T2207/30241 , G06V2201/031
Abstract: A system and method for facilitating DBS electrode trajectory planning using a machine learning (ML)-based feature identification scheme configured to identify and distinguish between various regions of interest (ROIs) and regions of avoidance (ROAs) in a patient's brain scan image. In one arrangement, standard orientation image slices as well as re-sliced images in non-standard orientations are provided in a labeled input dataset for training a CNN/ANN for distinguishing between ROIs and ROAs. Upon identification of the ROIs and ROAs in the patient's brain scan image, an optimal trajectory for implanting a DBS lead may be determined relative to a particular ROI while avoiding any ROAs.
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公开(公告)号：US11679264B2
公开(公告)日：2023-06-20
申请号：US17082299
申请日：2020-10-28
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Simeng Zhang , Hyun-Joo Park , Filippo Agnesi , Yagna Pathak , Erika Ross
CPC classification number: A61N1/36178 , A61N1/0551 , A61N1/36175 , A61N1/36071
Abstract: The present disclosure provides systems and methods for generating burst waveforms. An implantable neurostimulation system includes an implantable stimulation lead including a plurality of contacts, and an implantable pulse generator communicatively coupled to the stimulation lead. The pulse generator is configured to generate a waveform including a burst that includes a leading anodic pulse followed by alternating cathodic pulses and anodic pulses, each cathodic pulse in the burst having a greater amplitude than the previous cathodic pulse.
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公开(公告)号：US20230054788A1
公开(公告)日：2023-02-23
申请号：US17891099
申请日：2022-08-18
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Mary Khun Hor-Lao , Binesh Balasingh , Scott DeBates , Douglas Alfred Lautner , Yagna Pathak , Simeng Zhang , Diane Whitmer , Anahita Kyani , Hyun-Joo Park , Erika Ross , David Page , Ameya Nanivadekar , Dehan Zhu
Abstract: The present disclosure is directed to providing digital health services. In some embodiments, systems and methods for conducting virtual or remote sessions between patients and clinicians are disclosed. During the sessions, media content (e.g., images, video content, audio content, etc.) may be captured as the patient performs one or more tasks. The media content may be presented to the clinician and used to evaluate a condition of the patient or a state of the condition, adjust treatment parameters, provide therapy, or other operations to treat the patient. The analysis of the media content may be aided by one or more machine learning/artificial intelligence models that analyze various aspects of the media content, augment the media content, or other functionality to aid in the treatment of the patient.
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Patent Agency Ranking
公开(公告)号：US20230054076A1
公开(公告)日：2023-02-23
申请号：US17891087
申请日：2022-08-18
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Mary Khun Hor-Lao , Binesh Balasingh , Scott DeBates , Douglas Alfred Lautner , Yagna Pathak , Simeng Zhang , Diane Whitmer , Anahita Kyani , Hyun-Joo Park , Erika Ross , David Page , Ameya Nanivadekar , Plano Zhu
Abstract: The present disclosure is directed to providing digital health services. In some embodiments, systems and methods for conducting virtual or remote sessions between patients and clinicians are disclosed. During the sessions, media content (e.g., images, video content, audio content, etc.) may be captured as the patient performs one or more tasks. The media content may be presented to the clinician and used to evaluate a condition of the patient or a state of the condition, adjust treatment parameters, provide therapy, or other operations to treat the patient. The analysis of the media content may be aided by one or more machine learning/artificial intelligence models that analyze various aspects of the media content, augment the media content, or other functionality to aid in the treatment of the patient.
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公开(公告)号：US20220080202A1
公开(公告)日：2022-03-17
申请号：US17082318
申请日：2020-10-28
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Hyun-Joo Park , Simeng Zhang , Yagna Pathak , Erika Ross
Abstract: The present disclosure provides systems and methods for generating pulsed waveforms that approximate colored noise for use in a neurostimulation system. An implantable neurostimulation system includes an implantable stimulation lead including a plurality of contacts, and an implantable pulse generator communicatively coupled to the stimulation lead. The pulse generator is configured to generate a pulsed waveform that approximates colored noise using at least one of a thresholding method and an optimization method, and cause stimulation to be delivered by the stimulation lead based on the pulsed waveform.
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公开(公告)号：US11253706B2
公开(公告)日：2022-02-22
申请号：US16703176
申请日：2019-12-04
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor： Hyun-Joo Park
Abstract: The present disclosure provides systems and methods for selecting contacts for use in deep brain stimulation (DBS). A computing device includes a processor and a memory device communicatively coupled to the processor. The memory device includes instructions that, when executed, cause the processor to apply a spatial filter to local field potential (LFP) recordings for a plurality of contacts of a DBS lead, calculate a power spectral density (PSD) for each contact from the filtered LFP for that contact, calculate a parametric approximation for each PSD, select at least one frequency band based on the parametric approximations, calculate a spectral coherency matrix for each of the at least one selected frequency band, and calculate an eigenvector centrality for each spectral coherency matrix to facilitate identifying a contact for stimulation.
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公开(公告)号：US12109420B2
公开(公告)日：2024-10-08
申请号：US17091469
申请日：2020-11-06
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Anahita Kyani , Jagatkumar Shah , Douglas Lautner , Ali Taheri , Simeng Zhang , Yagna Pathak , Erika Ross , Hyun-Joo Park
IPC: A61N1/00 , A61B5/0215 , A61N1/365
CPC classification number: A61N1/36564 , A61B5/0215
Abstract: Provided herein is a computing system for optimizing a waveform, in communication with an implantable pulse generator, and including a computing device including a memory device and a processor communicatively coupled to the memory device. The processor is configured to: retrieve historical waveform data associated with a plurality of waveforms used in therapeutic sessions for a plurality of patients, the historical waveform data including a plurality of waveform parameters; analyzing the historical waveform data to determine preferred waveform parameters; determining that a patient is starting a new therapeutic session using the patient therapeutic device; displaying each of the preferred waveform parameters; prompting the user to accept or modify the displayed waveform parameters; optimizing the waveform parameters for the therapeutic session; and transmitting the optimized waveform parameters to the patient therapeutic device to start the therapeutic session.
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30.发明授权公开(公告)号：US11931572B1
公开(公告)日：2024-03-19
申请号：US17133985
申请日：2020-12-24
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor： Simeng Zhang , Hyun-Joo Park , Erika Ross
CPC classification number: A61N1/36034 , A61N1/0456 , A61N1/0492 , A61N1/06 , A61N1/323
Abstract: A noninvasive/minimally invasive neuromodulation system and method for providing therapy to a target neural tissue of a patient. In one arrangement, an example method comprises applying at least two input waveforms to respective pairs of electrodes affixed on the patient's skin or subcutaneously disposed relative to the target neural tissue, wherein the frequencies of the input waveforms are configured such that they combine, when simultaneously applied, to generate a beat waveform having a beat frequency due to interference. The beat waveform is causative of a transcutaneous/subcutaneous temporal interference (T/STI) electric field generated in the patient body, the T/STI electric field including an interference region at least partially overlapping the target neural tissue of the patient, wherein the beat frequency is of a value operative to impart a therapeutic effect to the target neural tissue.
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