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46 条记录 (耗时 0.065 秒)

    BARLEY AND USES THEREOF
    24.
    发明申请
    BARLEY AND USES THEREOF 有权

    公开(公告)号：US20210289730A1

    公开(公告)日：2021-09-23

    申请号：US17339571

    申请日：2021-06-04

    申请人： Zhongyi Li ,  Matthew Kennedy Morell

    发明人： Zhongyi Li ,  Matthew Kennedy Morell

    IPC分类号： A01H5/10 ,  C12N15/82 ,  C12Q1/25

    摘要： The invention provides barley grain comprising a reduced level or activity of starch synthase IIa protein and a starch content of at least 41% (w/w) and methods of producing, identifying and using same. The grain may comprise an amylase content of at least 50%, a β-glucan content of 5-9% (w/w) or greater than 9% (w/w), and/or a fructan content of 3-11% (w/w). The fructan may comprise a degree of polymerization from about 3 to about 12. For example, the plant and grain comprises a sex6-292 allele and/or an amo1 mutation. A food or beverage product, and methods of producing a food or beverage product, comprising obtaining or producing the subject grain and processing the grain to produce the product. Also contemplated are methods of improving one or mom indicators of health in a mammal comprising administering a composition comprising the subject barley grain or a product comprising same.

    HIGH FRUCTAN CEREAL PLANTS
    28.
    发明申请
    HIGH FRUCTAN CEREAL PLANTS 有权
    高科技谷物植物

    公开(公告)号：US20110281818A1

    公开(公告)日：2011-11-17

    申请号：US13008746

    申请日：2011-01-18

    申请人： Colin Leslie Dow Jenkins ,  Bryan Charles Clarke ,  Zhongyi Li ,  Matthew Kennedy Morell

    发明人： Colin Leslie Dow Jenkins ,  Bryan Charles Clarke ,  Zhongyi Li ,  Matthew Kennedy Morell

    IPC分类号： A61K31/733 ,  A61P1/00 ,  A61P19/08 ,  A61P3/00

    CPC分类号： C12N15/8245 ,  G01N33/50 ,  G01N2400/38

    摘要： The invention provides cereal plants having a high level of fructan useful for the production of a range of food, beverage, nutraceutical and pharmaceutical products. The invention provides methods of producing high-fructan products from plants modified to comprise a reduced level of an endogenous polypeptide with starch synthase activity, and products so produced. In some embodiments, plants are modified by introduction of an agent such as a nucleic acid molecule which down regulates endogenous starch synthase II gene expression.

    摘要翻译： 本发明提供了具有高水平的果聚糖的谷类植物，其用于生产一系列食品，饮料，营养药物和药物产品。 本发明提供了从修饰为包含具有淀粉合成酶活性的内源性多肽的降低水平的植物生产高果聚糖产物的方法以及如此制备的产品。 在一些实施方案中，通过引入下调调节内源淀粉合成酶II基因表达的核酸分子的试剂来修饰植物。

    PLANTS WITH MODIFIED STARCH METABOLISM
    29.
    发明申请
    PLANTS WITH MODIFIED STARCH METABOLISM 审中-公开
    具有改性淀粉代谢的植物

    公开(公告)号：US20110045127A1

    公开(公告)日：2011-02-24

    申请号：US12745237

    申请日：2008-11-27

    申请人： Jean-Philippe Francois Michel Ral ,  Zhongyi Li ,  Matthew Kennedy Morell

    发明人： Jean-Philippe Francois Michel Ral ,  Zhongyi Li ,  Matthew Kennedy Morell

    IPC分类号： A23L1/10 ,  A01H5/00 ,  A01H5/10 ,  A01G1/00 ,  A01D46/00

    CPC分类号： C12N15/8245 ,  C07K14/415 ,  C12N9/1294 ,  C12N15/8234 ,  C12N15/8261 ,  C12Y207/09004

    摘要： The specification provides methods of obtaining a genetically modified plant which has increased production potential compared to a control plant, the method comprising the steps of i) obtaining a plurality of plants at least one of which comprises in its genome a heterologous polynucleotide, ii) identifying from the plurality of plants a plant which has increased production potential relative to the control plant and comprises the heterologous polynucleotide, and iii) selecting the genetically modified plant, wherein the polynucleotide comprises a transcriptional control sequence operably linked to a nucleic acid sequence which encodes an agent that modifies endogenous starch phosphorylation and/or starch degradation in the plant. In some embodiments, the plant has increased endogenous glycosylase or increased digestibility compared to a control plant. In some specific embodiments, the endogenous starch phosphorylation and/or starch degradation is modified by modifying expression or activity of one or more enzymes selected from the group consisting of α-amylase (EC 3.2.1.1), β-amylase (EC 3.2.1.2), glucoamylase (EC 3.2.1.3), starch phosphorylase (EC2.4.1.1), glycosylase (EC 3.1.33), sucrase-isomaltase (EC 3.2.10), amylomaltase (EC 2.4.1.25), maltase (EC 3.2.1.20), isoamylase, and α-glucan, water dikinase (GWD, EC 2.7.9.4).

    摘要翻译： 本说明书提供了获得与对照植物相比具有增加的生产潜力的遗传修饰植物的方法，所述方法包括以下步骤：i）获得多个植物，其中至少一个在其基因组中包含异源多核苷酸，ii）鉴定 来自多个植物的植物相对于对照植物具有增加的生产潜力并且包含异源多核苷酸，以及iii）选择遗传修饰植物，其中所述多核苷酸包含可操作地连接到编码 修饰植物内源性淀粉磷酸化和/或淀粉降解的试剂。 在一些实施方案中，与对照植物相比，植物具有增加的内源糖基化酶或增加的消化率。 在一些具体实施方案中，内源性淀粉磷酸化和/或淀粉降解通过修饰选自以下的一种或多种酶的表达或活性来修饰：α-淀粉酶（EC 3.2.1.1），淀粉酶（EC 3.2。 1.2），葡糖淀粉酶（EC 3.2.1.3），淀粉磷酸化酶（EC2.4.1.1），糖基化酶（EC 3.1.33），蔗糖酶异麦芽糖酶（EC 3.2.10），淀粉麦芽糖酶（EC 2.4.1.25），麦芽糖酶 3.2.1.20），异淀粉酶和α-葡聚糖，水二激酶（GWD，EC 2.7.9.4）。