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公开(公告)号:US20220305747A1
公开(公告)日:2022-09-29
申请号:US17701819
申请日:2022-03-23
Applicant: Alcon Inc.
Inventor: Richard Charles Breitkopf , Zahra Bassampour , Chandana Kolluru , Steve Yun Zhang
Abstract: The invention relates to a method for producing embedded hydrogel contact lenses each having a magnetized insert that comprises magnetic particles and is centrally embedded in the bulk hydrogel material of the embedded hydrogel contact lens. During molding, a magnetized insert can be centered and held in position in a lens mold by using a magnet placed below the lens mold. The invention also relates to an embedded hydrogel contact lens produced from a method of the invention.
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公开(公告)号:US11427685B2
公开(公告)日:2022-08-30
申请号:US16365973
申请日:2019-03-27
Applicant: Alcon Inc.
Inventor: Daqing Wu , Steve Yun Zhang , Junhao Ge , Richard Charles Breitkopf , Augustine Twum Kumi , Weihong Lang
IPC: B29D11/00 , C08G77/442 , G02B1/04 , B29K83/00 , B29K105/00 , C08G77/00
Abstract: The invention provides a method for making silicone hydrogel contact lenses. The method of the invention is characterized by using an organic solvent as a processing-aid tool for controlling lens diameter without significantly affecting lens equilibrium water content during cast-molding of soft contact lenses from a polymerizable composition. By adjusting the weight percentage of the organic solvent in a polymerizable composition for making SiHy contact lenses, one can adjust lens diameter of produced SiHy lenses to meet target without affecting adversely the lens properties.
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公开(公告)号:US20220126541A1
公开(公告)日:2022-04-28
申请号:US17512431
申请日:2021-10-27
Applicant: Alcon Inc.
Inventor: Junhao Ge , Yuan Chang , Steve Yun Zhang , Michelle Plavnik , Augustine Twum Kumi , Daqing Wu
IPC: B29D11/00 , G02C7/04 , G02C7/10 , C08F230/08
Abstract: Described herein is a method for producing photochromic silicone hydrogel contact lenses in a relatively efficient and consistent manner from a polymerizable composition under a controlled thermal curing scheme. The main polymerizable components in the polymerizable composition are a high radical-reactive hydrophilic (meth)acrylamido monomer, a high radical-reactive siloxane-containing (meth)acrylamido monomer, and a polysiloxane vinylic crosslinker(s) free of low-reactive ethylenically unsaturated group as the main crosslinker. The thermal free radical initiator having a 10 hour half-life temperature (T10hλ) of from about 50° C. to about 90° C. The controlled thermal curing scheme includes maintaining a first curing temperature of from about (T10hλ−20)° C. to about T10hλ° C. for a first curing time and maintaining a second curing temperature of from about (T10hλ+10)° C. to about (T10hλ+35)° C. for a second curing time.
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公开(公告)号:US20210302625A1
公开(公告)日:2021-09-30
申请号:US17205169
申请日:2021-03-18
Applicant: Alcon Inc.
Inventor: Jing Cheng , Wei Liang , Steve Yun Zhang
Abstract: The invention is generally related to an insert for being embedded in a silicone hydrogel contact lens. The insert is made of a crosslinked materials which are rigid in dry state at room temperature (from about 22° C. to about 26° C.), have a high oxygen permeability and a high refractive index in fully hydrated state, and can become softer at a temperature great than 32° C. Such materials are useful for making inserts in embedded contact lenses for correcting corneal astigmatism, presbyopia, and color blindness lenses and for imparting photochromic characteristics to the lenses. The invention is also related to a method for making embedded silicone hydrogel contact lenses comprising an insert of the invention therein and to embedded silicone hydrogel contact lenses comprising an insert of the invention therein.
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公开(公告)号:US20210181379A1
公开(公告)日:2021-06-17
申请号:US17122109
申请日:2020-12-15
Applicant: Alcon Inc.
Inventor: Ying Zheng , Jang-Shing Chiou , Jinbo Dou , Yuan Chang , Junhao Ge , Steve Yun Zhang , Li Yao , Karen Belinda Sentell , Ye Hong
Abstract: The invention relates to an ophthalmic product which comprises a sealed and autoclave-sterilized lens package including (1) a post-autoclave packaging solution containing a polymeric surfactant having an HLB value of from about 11 to about 16 and a Mn of from about 800 to about 20,000 Daltons and (2) a readily-usable silicone hydrogel (SiHy) contact lens immersed in the packaging solution. The readily-usable SiHy contact lens comprises the polymeric surfactant thereon providing an excellent wettability to the readily-usable SiHy contact lens directly out of the lens package, and also the leachable polymeric surfactant which is physically distributed in the polymer matrix of the SiHy contact lens and can be released to the eye of a patient for at least 7 days of daily wear and to replenish the lens surface-bound polymeric surfactant to provide sustainable wettabilities to the contact lens and the eye.
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公开(公告)号:US20210011197A1
公开(公告)日:2021-01-14
申请号:US17038266
申请日:2020-09-30
Applicant: Alcon Inc.
Inventor: Daqing Wu , Junhao Ge , Steve Yun Zhang , Richard Charles Breitkopf , Xinming Qian , Zach Munoz , Matthew D. Nelson , Augustine Twum Kumi , Weihong Lang , Ying Zheng , Feng Jing , Frank Chang
Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.
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公开(公告)号:US20210009743A1
公开(公告)日:2021-01-14
申请号:US17038349
申请日:2020-09-30
Applicant: Alcon Inc.
Inventor: Jinyu Huang , Frank Chang , Steve Yun Zhang , Feng Jing
IPC: C08F290/06 , G02B1/04 , C08G77/20 , C08G77/16 , C08G77/392
Abstract: The invention provides a hydrophilized polydiorganosiloxane vinylic crosslinker which comprises (1) a polydiorganosiloxane polymer chain comprising dimethylsiloxane units and hydrophilized siloxane units each having one methyl substituent and one monovalent C4-C40 organic radical substituent having two to six hydroxyl groups, wherein the molar ratio of the hydrophilized siloxane units to the dimethylsiloxane units is from about 0.035 to about 0.15, and (2) two terminal (meth)acryloyl groups. The hydrophilized polydiorganosiloxane vinylic crosslinker has a number average molecular weight of from about 3000 Daltons to about 80,000 Daltons. The present invention is also related to a silicone hydrogel contact lens, which comprises repeating units derived from a hydrophilized polydiorganosiloxane vinylic crosslinker of the invention.
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公开(公告)号:US20200376788A1
公开(公告)日:2020-12-03
申请号:US16884536
申请日:2020-05-27
Applicant: Alcon Inc.
Inventor: Richard Charles Breitkopf , Changhong Yin , Steve Yun Zhang
Abstract: The invention relates to a pad printing instrument comprising an ink supply system capable of control the temperature, viscosity and colorant concentration of an ink in an ink cup. Such controls are achieved by continuously adding and mixing a cold ink having a composition identical to the ink in the ink cup but having a lower temperature. The continuous addition of a small amount of a cold ink into the ink cup could compensate heat generated by the friction between the ink cup and a cliché and could minimize the evaporation of a diluent in the ink and change in the concentration of colorants in the ink and ink viscosity. The invention also relates to use of a pad printing instrument comprising an ink supply system of the invention for producing colored hydrogel or silicone hydrogel contact lenses.
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公开(公告)号:US20250059330A1
公开(公告)日:2025-02-20
申请号:US18929889
申请日:2024-10-29
Applicant: Alcon Inc.
Inventor: Steve Yun Zhang , Daqing Wu , Junhao Ge , Richard Charles Breitkopf , Xinming Qian , Zach Munoz , Matthew D. Nelson , Augustine Twum Kumi , Weihong Lang , Ying Zheng , Feng Jing , Frank Chang
IPC: C08G77/442 , B29D11/00 , C08G77/12 , C08G77/14 , C08G77/20 , C08G77/388 , C08G77/392 , C08L83/10 , G02B1/04 , G02C7/04
Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.
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公开(公告)号:US12171871B2
公开(公告)日:2024-12-24
申请号:US17392448
申请日:2021-08-03
Applicant: ALCON INC.
Inventor: Junhao Ge , Steve Yun Zhang , Daqing Wu , Jing Cheng , Yuan Chang , Feng Jing , Jang-Shing Chiou , Stephen Raymond Perreault
Abstract: The present invention relates to a method to load a water insoluble phospholipid as nanoparticles to load into a hydrogel contact lens in autoclaving process during the hydrogel contact lens manufacturing process without an extra manufacturing step and without swelling the hydrogel contact lens with an organic solvent. The phospholipid nanoparticles loaded in hydrogel contact lens subsequently releases to the eye upon wearing.
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