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公开(公告)号：US20130165409A1
公开(公告)日：2013-06-27
申请号：US13727663
申请日：2012-12-27
发明人： Yong Moon Choi
IPC分类号： C07C271/02
CPC分类号： C07C271/02 , A61K31/047 , A61K31/164 , A61K31/165 , A61K31/325 , C07C33/26 , C07C33/36 , C07C271/12 , C07C271/16 , C07C271/24 , C07C271/28 , C07C2601/02 , C07C2601/14 , C07C2602/42 , C07F7/1804
摘要： A phenyl carbamate compound; a composition for treating and/or alleviating pain containing the phenyl carbamate compound or a pharmaceutically acceptable salt thereof as an active ingredient; a method of treating and/or alleviating pain comprising administering the phenyl carbamate compound or a pharmaceutically acceptable salt thereof to a patient in need of pain treatment; and a use of the phenyl carbamate compound or a pharmaceutically acceptable salt thereof in treating and/or alleviating pain, are provided.
摘要翻译： 苯基氨基甲酸酯化合物; 用于治疗和/或减轻含有苯基氨基甲酸酯化合物或其药学上可接受的盐作为活性成分的疼痛的组合物; 一种治疗和/或缓解疼痛的方法，包括向需要疼痛治疗的患者施用苯基氨基甲酸酯化合物或其药学上可接受的盐; 并且提供了苯基氨基甲酸酯化合物或其药学上可接受的盐在治疗和/或缓解疼痛中的用途。
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公开(公告)号：US11168052B2
公开(公告)日：2021-11-09
申请号：US15526502
申请日：2017-02-28
发明人： Yong Moon Choi
IPC分类号： C07C271/34 , C07C35/32 , C07C43/192 , C07F7/18 , C07C35/52
摘要： The present invention relates to a pharmaceutical composition for treating or preventing CNS disorders containing a carbamate derivative compound and/or pharmaceutically acceptable salt thereof as an active ingredient. Furthermore, the present invention relates to a method for treatment or prevention CNS disorders comprising administering a carbamate derivative compound in a pharmaceutically effective amount to a subject in need of treatment or prevention of CNS disorders.
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公开(公告)号：US09937145B2
公开(公告)日：2018-04-10
申请号：US15103611
申请日：2014-12-12
发明人： Yong Moon Choi
IPC分类号： A61K31/341 , A61K31/357 , A61K31/381 , A61K31/426 , A61K31/443 , A61K31/506 , A61K31/343 , A61K31/44 , A61K31/505
CPC分类号： A61K31/341 , A61K31/343 , A61K31/357 , A61K31/381 , A61K31/426 , A61K31/44 , A61K31/443 , A61K31/505 , A61K31/506
摘要： The present invention relates to a pharmaceutical composition for treating or preventing epilepsy containing a sulfamate derivative compound and/or pharmaceutically acceptable salt thereof as an active ingredient. Furthermore, the present invention relates to a method for treatment or prevention epilepsy comprising administering a sulfamate derivative compound in a pharmaceutically effective amount to a subject in need of treatment or prevention of epilepsy.
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公开(公告)号：US09624164B2
公开(公告)日：2017-04-18
申请号：US13727654
申请日：2012-12-27
发明人： Yong Moon Choi
IPC分类号： A61K31/27 , A01N47/10 , C07C271/02 , A61K31/165 , A61K31/047 , A61K31/164 , C07C33/26 , C07C271/12 , C07C271/24 , C07F7/18 , C07C271/28 , C07C271/16 , A61K31/325 , C07C33/36
CPC分类号： C07C271/02 , A61K31/047 , A61K31/164 , A61K31/165 , A61K31/325 , C07C33/26 , C07C33/36 , C07C271/12 , C07C271/16 , C07C271/24 , C07C271/28 , C07C2601/02 , C07C2601/14 , C07C2602/42 , C07F7/1804
摘要： A method for treatment or prevention epilepsy comprising administering a phenyl carbamate compound in a pharmaceutically effective amount to a subject in need of treatment or prevention of epilepsy is provided.
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25.发明申请Phenyl Carbamate Compound and a Composition for Neuroprotection Comprising the Same 审中-公开苯基氨基甲酸酯化合物和包含其的神经保护组合物公开(公告)号：US20160015680A1
公开(公告)日：2016-01-21
申请号：US14774898
申请日：2014-03-12
发明人： Yong Moon Choi
IPC分类号： A61K31/325
摘要： The present invention relates to a composition for neuroprotection comprising a phenyl carbamate compound and a method for providing neuroprotection therewith. The present invention ensures the enhancement of neuroprotection, such that it is promising for preventing or treating various diseases associated with neurological injury.
摘要翻译： 本发明涉及包含苯基氨基甲酸酯化合物的神经保护组合物及其神经保护的方法。 本发明确保神经保护作用的增强，从而有希望预防或治疗与神经损伤相关的各种疾病。
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26.发明申请PHENYLPROPYL CARBAMATE DERIVATIVES FOR USE IN PREVENTING OR TREATING MULTIPLE SCLEROSIS 审中-公开用于预防或治疗多发性硬化症的苯丙氨酸衍生物公开(公告)号：US20130184338A1
公开(公告)日：2013-07-18
申请号：US13727656
申请日：2012-12-27
发明人： Yong Moon Choi
IPC分类号： C07C271/28 , C07C271/24 , C07C271/12
CPC分类号： C07C271/02 , A61K31/047 , A61K31/164 , A61K31/165 , A61K31/325 , C07C33/26 , C07C33/36 , C07C271/12 , C07C271/16 , C07C271/24 , C07C271/28 , C07C2601/02 , C07C2601/14 , C07C2602/42 , C07F7/1804
摘要： A phenyl carbamate compound, and a method of treating and/or preventing multiple sclerosis comprising administering a pharmaceutically effective amount of the phenyl carbamate compound to a subject in need of treating and/or preventing multiple sclerosis, are provided.
摘要翻译： 苯基氨基甲酸酯化合物，以及治疗和/或预防多发性硬化的方法，包括向需要治疗和/或预防多发性硬化的受试者施用药学有效量的氨基甲酸苯酯化合物。
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公开(公告)号：US20130165408A1
公开(公告)日：2013-06-27
申请号：US13727654
申请日：2012-12-27
发明人： Yong Moon Choi
IPC分类号： C07C271/02
CPC分类号： C07C271/02 , A61K31/047 , A61K31/164 , A61K31/165 , A61K31/325 , C07C33/26 , C07C33/36 , C07C271/12 , C07C271/16 , C07C271/24 , C07C271/28 , C07C2601/02 , C07C2601/14 , C07C2602/42 , C07F7/1804
摘要： A method for treatment or prevention epilepsy comprising administering a phenyl carbamate compound in a pharmaceutically effective amount to a subject in need of treatment or prevention of epilepsy is provided.
摘要翻译： 一种用于治疗或预防癫痫的方法，其包括给予需要治疗或预防癫痫的受治疗者有效量的苯基氨基甲酸酯化合物。
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28.发明授权公开(公告)号：US11931332B2
公开(公告)日：2024-03-19
申请号：US17461695
申请日：2021-08-30
发明人： Yong Moon Choi
摘要： The present invention relates to a phenyl alkyl carbamate compound for use in preventing or treating neurodegenerative diseases. The phenyl alkyl carbamate compound of the present invention, prevented dopaminergic neuron loss, attenuated activation of astrocyte/microglia, repressed phosphorylated alpha-synuclein, and regulated phosphorylation levels of tau and acetylation levels of alpha-tubulin in the Parkinson's disease animal model. In addition, the phenyl alkyl carbamate compound of the present invention reduced the Amyloid-beta precursor protein and Amyloid-beta. Therefore, the phenyl alkyl carbamate compound of the present invention may be effectively used for preventing or treating neurodegenerative diseases.
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公开(公告)号：US10351519B2
公开(公告)日：2019-07-16
申请号：US15516133
申请日：2017-02-28
发明人： Yong Moon Choi
IPC分类号： A61P25/08 , A61P25/18 , C07C307/02 , C07D213/46 , C07D213/61 , C07D277/24 , C07D277/32 , C07D333/16
摘要： The present invention relates to a pharmaceutical composition for treating or preventing CNS disorders containing a sulfamate derivative compound and/or pharmaceutically acceptable salt thereof as an active ingredient. Furthermore, the present invention relates to a method for treatment or prevention CNS disorders comprising administering a sulfamate derivative compound in a pharmaceutically effective amount to a subject in need of treatment or prevention of CNS disorders.
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公开(公告)号：US09872847B2
公开(公告)日：2018-01-23
申请号：US14775092
申请日：2014-03-11
发明人： Yong Moon Choi
IPC分类号： C07C271/12 , C07C271/24 , A61K31/325 , A61K31/03 , A61K31/27
CPC分类号： A61K31/325 , A61K31/03 , A61K31/27 , C07C271/12 , C07C271/24 , C07C2601/02 , C07C2601/14 , C07C2601/16 , C07C2602/42
摘要： The present invention provides a pharmaceutical composition for preventing and/or treating a movement disorder comprising the phenyl carbamate compound as an active ingredient, and a use of the phenyl carbamate compound for preventing and/or treating movement disorder.
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