公开(公告)号：US11304889B2

公开(公告)日：2022-04-19

申请号：US15840050

申请日：2017-12-13

Applicant: Colgate-Palmolive Company

Inventor： Shyamala Pillai ,  Guofeng Xu ,  LaTonya Kilpatrick-Liverman ,  Xiang Chen ,  Suman Chopra ,  Robert Dicosimo ,  Mark S. Payne ,  Mahmoud Hassan

IPC: A61K8/66 ,  A61K8/46 ,  A61K8/37 ,  A61Q11/00 ,  A61K8/22 ,  A61K8/81 ,  A61K8/06 ,  A61C19/06 ,  A61K8/44 ,  A61K8/31 ,  A61K8/49

Abstract: An oral care composition including a hydrophobic phase and a hydrophilic phase is disclosed. The hydrophobic phase may include a source of hydrogen peroxide and an acyl donor, and the hydrophilic phase may include an enzyme having perhydrolytic activity that catalyzes the generation of peracetic acid between the source of hydrogen peroxide and the acyl donor.

公开(公告)号：US10758472B2

公开(公告)日：2020-09-01

申请号：US15900346

申请日：2018-02-20

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Lynette Zaidel ,  Guisheng Pan ,  Suman Chopra ,  Prakasarao Mandadi ,  Michael Prencipe

IPC: A61K8/00 ,  A61K8/81 ,  A61K8/02 ,  A61K8/22 ,  A61Q11/00 ,  A61Q11/02 ,  A61K8/24 ,  A61K8/90 ,  A61K8/49 ,  A61K8/891

Abstract: Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.

公开(公告)号：US10076476B2

公开(公告)日：2018-09-18

申请号：US15528926

申请日：2015-12-09

Applicant: Colgate-Palmolive Company

Inventor： Lin Fei ,  Suman Chopra

IPC: A61K8/22 ,  A61K8/49 ,  A61K8/34 ,  A61K8/27 ,  A61K8/81 ,  A61Q11/00 ,  A61K8/37

CPC classification number: A61K8/22 ,  A61K8/345 ,  A61K8/375 ,  A61K8/39 ,  A61K8/4973 ,  A61K8/8176 ,  A61Q11/00

Abstract: Provided is an oral care composition comprising a peroxide source, a polyhydric alcohol and a surfactant system having an HLB value of from 4 to 13, wherein the combined amount of the polyhydric alcohol and the surfactant system is from 60 weight % to 95 weight % by total weight of the composition, and wherein the weight ratio of the polyhydric alcohol to the surfactant system is from 9:1 to 1:4. The composition is resistant to peroxide decomposition.

公开(公告)号：US20180177709A1

公开(公告)日：2018-06-28

申请号：US15903564

申请日：2018-02-23

Applicant: Colgate-Palmolive Company

Inventor： Thomas Boyd ,  Dennis Ontumi ,  Prakasarao Mandadi ,  Suman Chopra

IPC: A61K8/81 ,  A61Q11/00 ,  A61K8/04 ,  A61K8/49 ,  A61K8/92 ,  A61K8/89 ,  A61C19/06 ,  A61K8/22 ,  A61K8/892 ,  A61K8/891

CPC classification number: A61K8/8176 ,  A61C19/066 ,  A61K8/042 ,  A61K8/22 ,  A61K8/49 ,  A61K8/89 ,  A61K8/891 ,  A61K8/892 ,  A61K8/92 ,  A61K2800/31 ,  A61K2800/40 ,  A61K2800/48 ,  A61K2800/54 ,  A61K2800/872 ,  A61Q11/00

Abstract: Described herein are whitening compositions comprised of a peroxide component, and an adhesion system, which effectively provide whitening using a remarkably low level of peroxide. Methods of making and using these compositions are also described herein.

公开(公告)号：US20170156837A1

公开(公告)日：2017-06-08

申请号：US15434258

申请日：2017-02-16

Applicant: Colgate-Palmolive Company

Inventor： Michael Prencipe ,  Suman Chopra ,  Joseph Thomas Norris ,  Adolfo Serrano

IPC: A61C19/06 ,  A61C17/02 ,  A61C1/00 ,  A61Q11/00 ,  A46B9/00 ,  A46B11/00 ,  A61K8/22 ,  A61C3/00 ,  A46B9/02

CPC classification number: A61C19/066 ,  A46B9/005 ,  A46B9/021 ,  A46B9/025 ,  A46B11/0024 ,  A46B11/0027 ,  A46B17/04 ,  A46B2200/10 ,  A46B2200/1046 ,  A46B2200/20 ,  A61C1/0092 ,  A61C3/005 ,  A61C17/0202 ,  A61C19/063 ,  A61K8/22 ,  A61K8/8147 ,  A61K2800/87 ,  A61K2800/92 ,  A61Q11/00

Abstract: A method for applying a composition to teeth and a dispenser for dispensing a composition. The method of the present invention is directed to the storage and dispensing of a composition. During storage and subsequent use the composition in the storage chamber must be maintained segregated from the applicator surface. This is accomplished by delivering the composition from the storage chamber through a delivery channel having a length and a cross-sectional diameter sufficient to preclude the migration of moisture and the enzyme catalase from the application surface to the storage chamber. The composition is applied to teeth by means of bristles, a sponge surface or fibrillated surface. This applicator can be used with both aqueous and non-aqueous compositions.

公开(公告)号：US11596593B2

公开(公告)日：2023-03-07

申请号：US17248391

申请日：2021-01-22

Applicant: Colgate-Palmolive Company

Inventor： Lynette Zaidel ,  Guisheng Pan ,  Suman Chopra ,  Prakasarao Mandadi ,  Michael Prencipe

IPC: A61K8/22 ,  A61K8/81 ,  A61K8/02 ,  A61Q11/00 ,  A61Q11/02 ,  A61K8/24 ,  A61K8/90 ,  A61K8/49 ,  A61K8/891

Abstract: Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.

公开(公告)号：US11324677B1

公开(公告)日：2022-05-10

申请号：US17519931

申请日：2021-11-05

Applicant: Colgate-Palmolive Company

Inventor： Xiang Chen ,  Suman Chopra ,  Lin Fei

IPC: A61K8/22 ,  A61K8/86 ,  A61K8/81 ,  A61K8/24 ,  A61Q11/00 ,  A61K8/21

Abstract: Disclosed herein are oral care compositions comprising a peroxide whitening complex in an amount to provide from 3.5% to 7% of hydrogen peroxide by weight of the composition, and a block copolymer of ethylene oxide and propylene oxide in an amount of from 40% to 60% by weight of the composition. Methods of making and using the dentifrices are also provided.

公开(公告)号：US11083674B2

公开(公告)日：2021-08-10

申请号：US16204834

申请日：2018-11-29

Applicant: Colgate-Palmolive Company

Inventor： Guisheng Pan ,  Dennis Ontumi ,  Lin Fei ,  Suman Chopra ,  Tatiana Brinzari ,  Michael Stranick ,  Long Pan

IPC: A61K8/24 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/20

Abstract: Compounds and methods for preparing and using the compounds are disclosed herein. The method for preparing the compounds may include contacting a metal ion or salt thereof with an alkali metal polyphosphate salt in an aqueous medium. The method may also include adding a base to increase a pH of the aqueous medium.

公开(公告)号：US11033476B2

公开(公告)日：2021-06-15

申请号：US16566932

申请日：2019-09-11

Applicant: Colgate-Palmolive Company

Inventor： Jennifer Gronlund ,  Guofeng Xu ,  Venda Porter Maloney ,  Junhong Mao ,  Shaotang Yuan ,  Suman Chopra ,  Jodie Parker ,  Rajnish Kohli ,  Robert Dicosimo ,  Kari A. Fosser ,  Sharon L. Haynie ,  Mark S. Payne ,  John T. Gannon

IPC: A61K8/66 ,  A61K8/81 ,  A61K8/37 ,  A61K8/25 ,  A61Q11/00 ,  A61K8/22

Abstract: An oral care composition including an orally acceptable vehicle is disclosed. The orally acceptable vehicle includes a source of hydrogen peroxide, an acyl donor, and an enzyme that catalyzes the generation of peracetic acid between the source of hydrogen peroxide and the acyl donor.

公开(公告)号：US10512596B2

公开(公告)日：2019-12-24

申请号：US15533466

申请日：2014-12-19

Applicant: Colgate-Palmolive Company

Inventor： Venda Maloney ,  Suman Chopra ,  Hallena Strotman

IPC: A61K8/02 ,  A61Q11/00 ,  A61K8/73 ,  A61K8/21 ,  A61K8/34 ,  A61K8/44 ,  A61K8/81

Abstract: A tooth whitening oral care composition is made by combining ingredients comprising flakes of a water soluble whitening film, a dye with a hue angle in the CIELAB system ranging from 200 to 320 degrees, and an orally acceptable carrier vehicle. The flakes of the water soluble whitening film comprise: (a) a film-forming polymer comprising hydroxyalkyl cellulose wherein the hydroxyalkyl cellulose has a viscosity of about 1 to about 1000 millipascal seconds (mPa·s) as determined as a 2% by weight aqueous solution of the film-forming polymer at 20 C using a Ubbelohde tube viscometer; and (b) a pigment with a hue angle in the CIELAB system ranging from 200 to 320 degrees.