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公开(公告)号：US08397732B2
公开(公告)日：2013-03-19
申请号：US10731868
申请日：2003-12-09
IPC分类号： A61B19/00
CPC分类号： A61N1/375 , A61N1/3605 , A61N1/3754 , A61N1/3758
摘要： In general, the invention is directed to techniques for implantation of a low-profile implantable medical device (IMD) in the body of a patient. In an exemplary embodiment, the low-profile IMD is implanted under the scalp. When the treatment or monitoring site is in or on the head of the patient, the low-profile IMD can be implanted under the scalp proximate to the treatment or monitoring site. In one embodiment, the invention is directed to a method that includes making an incision in the scalp of a head of a patient to create a scalp flap, exposing a skull beneath the scalp flap, creating a pocket between the scalp and the skull, and placing at least a portion of a low-profile IMD in the pocket. The low-profile IMD may include a plurality of modules, covered in part by a flexible overmold.
摘要翻译： 通常，本发明涉及用于在患者体内植入低轮廓可植入医疗装置（IMD）的技术。 在示例性实施例中，将低调IMD植入头皮下。 当治疗或监测部位位于患者头部或头部时，可以将低调的IMD植入到靠近治疗或监测部位的头皮下。 在一个实施例中，本发明涉及一种方法，其包括在患者的头部的头皮中形成切口以产生头皮瓣，暴露头皮下的头骨，在头皮和头骨之间产生口袋，以及 将低调IMD的至少一部分放置在口袋中。 低调的IMD可以包括多个模块，部分由柔性包覆模制覆盖。
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公开(公告)号：US07881796B2
公开(公告)日：2011-02-01
申请号：US11831333
申请日：2007-07-31
IPC分类号： A61N1/08
摘要： An implantable medical device (IMD) including a nonhermetic battery is described. The IMD includes components and a power source module that includes the nonhermetic battery. The IMD also includes a barrier to substantially impede movement of substances from the nonhermetic battery to the components. The barrier may include a hermetic feedthrough, a gel, a polymer, or a solid electrolyte within the nonhermetic battery, and a seal member. The barrier may also be a material that encapsulates the nonhermetic battery and a getter within the IMD. In some embodiments, the IMD comprises a modular IMD including an interconnect member. In that case, the barrier may include a material that fills at least a portion of a void defined by the interconnect member. A length and a cross-sectional area of the interconnect member may also act as a barrier.
摘要翻译： 描述了包括非密封电池的可植入医疗装置（IMD）。 IMD包括组件和包含非密封电池的电源模块。 IMD还包括阻止物质从非密封电池移动到部件的屏障。 阻挡层可以包括非密封电池内的密封馈通，凝胶，聚合物或固体电解质，以及密封构件。 屏障还可以是在IMD内封装非密封电池和吸气剂的材料。 在一些实施例中，IMD包括包括互连构件的模块化IMD。 在这种情况下，阻挡层可以包括填充由互连构件限定的空隙的至少一部分的材料。 互连构件的长度和横截面积也可以用作屏障。
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公开(公告)号：US07844343B2
公开(公告)日：2010-11-30
申请号：US10945739
申请日：2004-09-20
IPC分类号： A61N1/00
CPC分类号： A61N1/08 , A61N1/05 , A61N1/0534 , A61N1/0551 , A61N1/086 , A61N1/36071
摘要： A medical lead is provided for use in a pulse stimulation system of the type which includes a pulse generator for producing electrical stimulation therapy. The lead comprises an elongate insulating body and at least one electrical conductor within the insulating body. The conductor has a proximal end configured to be electrically coupled to the pulse generator and has a DC resistance in the range of 375-2000 ohms. At least one distal electrode is coupled to the conductor.
摘要翻译： 提供了一种用于包括用于产生电刺激治疗的脉冲发生器的脉冲刺激系统的医疗引线。 引线包括细长绝缘体和绝缘体内的至少一个电导体。 导体具有被配置为电耦合到脉冲发生器的近端，并具有在375-2000欧姆范围内的直流电阻。 至少一个远端电极耦合到导体。
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公开(公告)号：US07676271B2
公开(公告)日：2010-03-09
申请号：US11689943
申请日：2007-03-22
IPC分类号： A61N1/36
CPC分类号： A61N1/0551 , A61N1/0502 , A61N1/36017 , A61N1/36021 , A61N1/36071
摘要： A process is described for non-invasively screening a patient to select a stimulation site for treatment of head, neck or facial pain and tension symptoms caused by disorders such as occipital neuralgia. The screening process involves application of a transcutaneous stimulation screening device, a percutaneous micro-electrode screening device, and a temporary implantable screening device to the patient to select a site for chronic implantation.
摘要翻译： 描述了一种非侵入式筛选患者以选择用于治疗头部，颈部或面部疼痛的刺激部位和由诸如枕骨神经痛等疾病引起的紧张症状的过程。 筛选过程包括将经皮刺激筛选装置，经皮微电极筛选装置和临时植入式筛选装置应用于患者以选择用于慢性植入的部位。
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公开(公告)号：US07664552B2
公开(公告)日：2010-02-16
申请号：US11800640
申请日：2007-05-07
IPC分类号： A61N1/36
CPC分类号： A61N1/0551 , A61N1/0502 , A61N1/36017 , A61N1/36021 , A61N1/36071
摘要： The disclosure describes a process for non-invasively screening a patient to select a stimulation site for treatment of head, neck or facial pain and tension symptoms caused by disorders such as occipital neuralgia. The screening process involves application of a transcutaneous stimulation screening device, a percutaneous micro-electrode screening device, and a temporary implantable screening device to the patient to select a site for chronic implantation.
摘要翻译： 本公开描述了非侵入式筛选患者以选择用于治疗头部，颈部或面部疼痛的刺激部位和由诸如枕骨神经痛等疾病引起的紧张症状的方法。 筛选过程包括将经皮刺激筛选装置，经皮微电极筛选装置和临时植入式筛选装置应用于患者以选择用于慢性植入的部位。
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公开(公告)号：US20090240303A1
公开(公告)日：2009-09-24
申请号：US12480467
申请日：2009-06-08
IPC分类号： A61N1/34
CPC分类号： A61N1/0504 , A61N1/0456 , A61N1/0476 , A61N1/0492 , A61N1/0502 , A61N1/36071 , A61N1/3756
摘要： The disclosure describes an implantable neurostimulator device for delivery of neurostimulation to treat head, neck, or facial pain or tension, including pain or tension caused by occipital neuralgia. The device may be a neurostimulation device having a miniaturized housing with a low profile that permits subcutaneous implantation at a stimulation site directly adjacent a neuralgic region at the back of the neck of a patient. For example, the device may be subcutaneously implanted at the back of the neck of a patient to relieve symptoms of occipital neuralgia.
摘要翻译： 本公开描述了用于递送神经刺激以治疗头部，颈部或面部疼痛或张力的可植入神经刺激器装置，包括由枕骨神经痛引起的疼痛或张力。 该装置可以是具有小型化的壳体的神经刺激装置，其具有允许在紧邻患者颈部后方的神经痛区域的刺激部位皮下植入。 例如，该装置可以皮下植入患者颈部的后部以减轻枕骨神经痛的症状。
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公开(公告)号：US07389147B2
公开(公告)日：2008-06-17
申请号：US11119420
申请日：2005-04-29
IPC分类号： A61N1/00
CPC分类号： A61B5/053 , A61B5/04012 , A61B5/0402 , A61B5/103 , A61N1/36071 , A61N1/36521 , A61N1/37247 , G06F19/00 , G16H40/63
摘要： Techniques for selectably providing either constant voltage or constant current stimulation are described. A programming device provides a user interface by which a user selects either constant voltage or constant current stimulation, and selects either a voltage or current amplitude based on the selected stimulation mode. The programming device configures a medical device to provide the selected mode of stimulation at the selected amplitude. For example, when a medical device has constant voltage stimulation circuitry, e.g., circuitry including a voltage source, and the user selects constant current stimulation, the programming device configures the medical device to adjust the voltage amplitude based on a measured impedance to provide substantially constant current amplitude.
摘要翻译： 描述了可选择地提供恒定电压或恒定电流刺激的技术。 编程设备提供用户界面，用户通过该界面用户选择恒定电压或恒定电流刺激，并且基于所选择的刺激模式选择电压或电流幅度。 编程设备配置医疗设备以在所选择的幅度提供所选择的刺激模式。 例如，当医疗设备具有恒定电压刺激电路（例如，包括电压源的电路）并且用户选择恒定电流刺激时，编程设备配置医疗设备以基于测量的阻抗来调整电压幅度以提供基本上恒定的 电流幅度。
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公开(公告)号：US09162072B2
公开(公告)日：2015-10-20
申请号：US11526514
申请日：2006-09-25
申请人： Ruchika Singhal , Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Paulette C. Olson , Erik R. Scott , James E. Randall
发明人： Ruchika Singhal , Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Paulette C. Olson , Erik R. Scott , James E. Randall
CPC分类号： A61N1/375 , A61B2560/0443 , A61N1/0526 , A61N1/3605
摘要： An implantable medical device with lubricious material permits implantable medical devices to have a reduced friction between the device and at least a portion of the surrounding tissue. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the tissue. The lubricious material may be provided on or impregnated in the housing or the member. In some embodiments, the device is configured for implantation in the head of a human body. In other embodiments, the device is configured for implantation between the cranium and the scalp. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled together to provide a smaller profile.
摘要翻译： 具有润滑材料的可植入医疗装置允许植入式医疗装置在装置与周围组织的至少一部分之间具有减小的摩擦。 可植入医疗装置可以具有壳体，或者可以具有壳体和用于在装置和组织之间提供平滑界面的构件。 润滑材料可以设置在或浸渍在壳体或构件中。 在一些实施例中，该装置被配置用于植入人体的头部。 在其他实施例中，该装置被配置用于在颅骨和头皮之间植入。 在一些实施例中，设备包括单个模块，而在其他实施例中，多个模块耦合在一起以提供较小的轮廓。
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29.发明授权Implantable neurostimulator device with bellows-like element coupling first and second housing portions 有权具有波纹管状元件联接第一和第二壳体部分的可植入神经刺激器装置公开(公告)号：US08744582B2
公开(公告)日：2014-06-03
申请号：US12611504
申请日：2009-11-03
IPC分类号： A61N1/375
CPC分类号： A61N1/0504 , A61N1/0456 , A61N1/0476 , A61N1/0492 , A61N1/0502 , A61N1/36071 , A61N1/3756
摘要： The disclosure describes an implantable neurostimulator device for delivery of neurostimulation to treat head, neck, or facial pain or tension, including pain or tension caused by occipital neuralgia. The device may be a neurostimulation device having a miniaturized housing with a low profile that permits subcutaneous implantation at a stimulation site directly adjacent a neuralgic region at the back of the neck of a patient. For example, the device may be subcutaneously implanted at the back of the neck of a patient to relieve symptoms of occipital neuralgia.
摘要翻译： 本公开描述了用于递送神经刺激以治疗头部，颈部或面部疼痛或张力的可植入神经刺激器装置，包括由枕骨神经痛引起的疼痛或张力。 该装置可以是具有小型化的壳体的神经刺激装置，其具有允许在紧邻患者颈部后方的神经痛区域的刺激部位皮下植入。 例如，该装置可以皮下植入患者颈部的后部以减轻枕骨神经痛的症状。
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公开(公告)号：US08666497B2
公开(公告)日：2014-03-04
申请号：US12942806
申请日：2010-11-09
申请人： Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Mark S. Lent , Keith A. Miesel , James E. Cabak
发明人： Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Mark S. Lent , Keith A. Miesel , James E. Cabak
IPC分类号： A61N1/372
CPC分类号： A61N1/375 , A61N1/3605 , A61N1/3754 , A61N1/3758
摘要： In an implantable medical device having individual modules, a coupling module couples the modules to one another. The coupling module supports electrical and/or mechanical coupling of the modules. The coupling module may assume a variety of shapes or configurations. The various embodiments of the coupling module may offer the modules varying degrees of freedom of movement relative to one another.
摘要翻译： 在具有各个模块的可植入医疗装置中，耦合模块将模块彼此连接。 联接模块支持模块的电气和/或机械耦合。 联接模块可呈现各种形状或构型。 联接模块的各种实施例可以提供模块相对于彼此的不同移动自由度。
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