公开(公告)号：US07825206B2

公开(公告)日：2010-11-02

申请号：US11956525

申请日：2007-12-14

申请人： Thomas Neumann ,  Wilfried Knott

发明人： Thomas Neumann ,  Wilfried Knott

IPC分类号： C08G77/18

CPC分类号： C08G77/08 ,  C08G77/16 ,  C08G77/42

摘要： The invention provides a process for preparing SiOC-bonded polyorganosiloxanes by reacting, by processes known per se, hydroxyl-containing compounds with a stoichiometric excess of polyorganosiloxanes which contain —Si(H) units and are of the general formula (I) in the presence of one or more element compounds of main group III and/or of transition group 3 as a catalyst, wherein the reaction, on completion of conversion of the compounds containing hydroxyl groups, is continued until no further ≡Si—H groups are detectable by gas volumetric means, and also the compounds prepared in this way and their use.

摘要翻译： 本发明提供了一种制备SiOC键合的聚有机硅氧烷的方法，其通过本身已知的方法使含羟基化合物与含有-Si（H）单元的化学计量过量的聚有机硅氧烷在通式（I）的存在下反应， 的主要III族和/或过渡族3的元素化合物作为催化剂，其中在含羟基的化合物的转化完成时的反应继续进行，直到不再有气体可以检测到≡Si-H基团 体积的方法，以及以这种方式制备的化合物及其用途。

公开(公告)号：US20090317787A1

公开(公告)日：2009-12-24

申请号：US12541707

申请日：2009-08-14

申请人： Thomas Neumann

发明人： Thomas Neumann

IPC分类号： A01N1/02 ,  C12N5/08

CPC分类号： C12N5/0691 ,  C12M21/08 ,  C12M23/06 ,  C12M23/16 ,  C12M23/20 ,  C12M29/10 ,  C12N2533/50

摘要： Creating a tissue structure in vitro includes juxtaposing mandrels on a culture/perfusion device frame where the mandrels are spaced apart substantially parallel to each other and connecting the mandrels to tubes including an upstream tubes and downstream tubes. The upstream tubes are connected with an upstream manifold and the downstream tubes are connected to a downstream manifold. The frame and the mandrels are sterilized, coated and seeded with cells that multiply and form circular layers around each of the mandrels until the circular layers merge into a tissue structure which is subjected to a growth medium. The mandrels are extracted and the tissue structure is perfused.

摘要翻译： 在体外创建组织结构包括在培养/灌注装置框架上并置心轴，其中心轴彼此间隔开并且将心轴连接到包括上游管和下游管的管。 上游管与上游歧管连接，下游管连接到下游歧管。 框架和心轴被消毒，涂覆并种植有细胞，每个细胞在每个心轴周围形成圆形层，直到圆形层合并成经历生长培养基的组织结构。 提取心轴并灌注组织结构。

公开(公告)号：US20090107364A1

公开(公告)日：2009-04-30

申请号：US11911720

申请日：2006-03-13

申请人： Horst-Michael Ludwig ,  Thomas Neumann

发明人： Horst-Michael Ludwig ,  Thomas Neumann

IPC分类号： C04B14/02 ,  B32B5/16 ,  B28C7/04

CPC分类号： C04B22/064 ,  C04B28/02 ,  C04B2103/004 ,  C04B2103/12 ,  C04B2111/00146 ,  C04B2111/0075 ,  C04B2111/60 ,  C04B2111/72 ,  Y10T428/2982 ,  C04B20/008 ,  C04B14/06 ,  C04B2103/30 ,  C04B20/10

摘要： The invention relates to a hydraulic binding agent comprising a binding agent component having free-flowing or solidifying properties when water is added and an acceleration component which is used to accelerate solidification. The acceleration component contains ultrafine calcium hydroxide having a high specific surface and low grain size.

摘要翻译： 本发明涉及一种水硬性粘合剂，其包含当加入水时具有自由流动或固化性能的粘合剂组分和用于加速固化的加速组分。 加速成分含有比表面积高，粒径小的超细氢氧化钙。

公开(公告)号：US20080227923A1

公开(公告)日：2008-09-18

申请号：US11755441

申请日：2007-05-30

申请人： Klaus-Deiter Klein ,  Thomas Neumann

发明人： Klaus-Deiter Klein ,  Thomas Neumann

IPC分类号： C08F8/04

CPC分类号： C08G77/46 ,  C08G77/34

摘要： The invention relates to a process for the treatment of polyoxyalkylene-polysiloxane block copolymers or alkylpolysiloxane-polyoxyalkylenepolysiloxane block copolymers in which the polysiloxane blocks are bonded to the polyether blocks or alkyl radicals by SiC bonds, wherein the polyoxyalkylene-polysiloxane block copolymers or alkylpolysiloxane-polyoxyalkylenepolysiloxane block copolymers or the solutions thereof are treated with flowing hydrogen gas and optionally a further inert gas in the presence of a combination of hydrogenation catalysts known per se and acid-activated carrier materials and water at temperatures of from 20 to 200° C. and atmospheric pressure over a period of from 0.5 to 10 hours.

摘要翻译： 本发明涉及一种用于处理聚氧化烯 - 聚硅氧烷嵌段共聚物或烷基聚硅氧烷 - 聚氧亚烷基聚硅氧烷嵌段共聚物的方法，其中聚硅氧烷嵌段通过SiC键与聚醚嵌段或烷基键合，其中聚氧化烯 - 聚硅氧烷嵌段共聚物或烷基聚硅氧烷 - 聚氧亚烷基聚硅氧烷 嵌段共聚物或其溶液在流动的氢气和任选的另外的惰性气体下，在本身已知的氢化催化剂和酸活化的载体材料和水的温度下，在20〜200℃的温度和大气压下进行处理 压力为0.5〜10小时。

公开(公告)号：US20070224677A1

公开(公告)日：2007-09-27

申请号：US11388920

申请日：2006-03-24

申请人： Thomas Neumann

发明人： Thomas Neumann

IPC分类号： C12N5/08 ,  C12M3/00 ,  C12N5/06

CPC分类号： C12N5/0691 ,  C12M21/08 ,  C12M23/06 ,  C12M23/16 ,  C12M23/20 ,  C12M29/10 ,  C12N2533/50

摘要： Microvessel networks are produced in vitro from tissue-engineered parent vessels sprouting into a supporting matrix, as for example gels, of extracellular matrix proteins. The microvessel systems are integrated into devices that allow for controlled perfusion with fluids. The vessels may include cells from one cell type, for example, endothelial cells, or from combinations of two or more cell types.

摘要翻译： 微血管网络在体外从组织工程化的母体血管发育成支持基质，例如凝胶，细胞外基质蛋白。 微血管系统集成到允许用流体控制灌注的装置中。 血管可以包括来自一种细胞类型的细胞，例如内皮细胞，或两种或多种细胞类型的组合。

公开(公告)号：US20060041097A1

公开(公告)日：2006-02-23

申请号：US11205878

申请日：2005-08-17

申请人： Sascha Herrwerth ,  Thomas Neumann ,  Isabella Ulrich-Brehm

发明人： Sascha Herrwerth ,  Thomas Neumann ,  Isabella Ulrich-Brehm

IPC分类号： C08G77/08 ,  C08G77/06

CPC分类号： B01J31/146 ,  C08G77/08 ,  C08G77/38 ,  C08G77/46 ,  C08K5/55

摘要： The invention relates to a catalytic system for the dehydrogenative condensation of polyorganosiloxanes with alcohols, consisting of at least one boron compound and at least one synergistically active compound, and to a process for converting polyorganosiloxanes, in which one hydrogen atom bonded to the silicon is replaced by an alkoxide radical using the inventive catalytic system.

摘要翻译： 本发明涉及聚有机硅氧烷与醇的脱氢缩合的催化体系，其由至少一种硼化合物和至少一种协同活性化合物组成，以及转化聚有机硅氧烷的方法，其中与硅键合的一个氢原子被替换 通过使用本发明的催化体系的醇盐基团。

公开(公告)号：US20050136269A1

公开(公告)日：2005-06-23

申请号：US11013639

申请日：2004-12-16

申请人： Hardi Doehler ,  Jutta Esselborn ,  Sascha Herrwerth ,  Thomas Neumann

发明人： Hardi Doehler ,  Jutta Esselborn ,  Sascha Herrwerth ,  Thomas Neumann

IPC分类号： C08G77/08 ,  C08G77/38 ,  C09D183/06 ,  B32B9/04 ,  C08G77/04 ,  C08L83/04

CPC分类号： C08G77/38 ,  C08G77/08 ,  C09D183/06 ,  Y10T428/31663

摘要： The present invention accordingly provides new organopolysiloxanes having (meth)acrylic ester groups attached pendent and terminally or only pendent via SiOC groups, of the general average formula (I) and also provides a process for preparing the compounds by reacting polysiloxanes containing SiH groups with (meth)acrylated monoalcohols and/or (meth)acrylated polyalcohols using Lewis-acidic catalysts or catalysts comprising a carboxylic acid and salts thereof.

摘要翻译： 因此，本发明提供了具有通过通式（I）的SiOC基团连接的侧面和末端或仅悬挂的（甲基）丙烯酸酯基团的新的有机聚硅氧烷，并且还提供了通过使含有SiH基团的聚硅氧烷与（ 甲基）丙烯酸酯化的一元醇和/或（甲基）丙烯酸酯化的多元醇，其使用路易斯酸性催化剂或包含羧酸的催化剂及其盐。

公开(公告)号：US20110070183A1

公开(公告)日：2011-03-24

申请号：US12888603

申请日：2010-09-23

申请人： Thomas Neumann ,  Burghard Gruning ,  Anna Howe ,  Dana Adkins ,  Jerry Reddinger

发明人： Thomas Neumann ,  Burghard Gruning ,  Anna Howe ,  Dana Adkins ,  Jerry Reddinger

IPC分类号： A61K8/89 ,  C08G77/38 ,  A61Q19/00 ,  A61Q19/04 ,  A61Q1/10 ,  A61Q1/00

CPC分类号： C08G77/46 ,  A61K8/06 ,  A61K8/891 ,  A61Q1/06 ,  A61Q1/10 ,  A61Q17/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/002 ,  A61Q19/04 ,  B01F17/0071 ,  C08G77/38 ,  C08L83/12

摘要： The invention relates to crosslinked organopolysiloxanes which are linked by a polyether building block via the Si atoms, to emulsifier systems which have these crosslinked organopolysiloxanes, and also to cosmetic, dermatological or pharmaceutical formulations comprising a crosslinked organopolysiloxane or an emulsifier system comprising these.

摘要翻译： 本发明涉及通过Si原子由聚醚结构单元连接的交联的有机聚硅氧烷，具有这些交联的有机聚硅氧烷的乳化剂体系，以及包含交联的有机聚硅氧烷或包含它们的乳化剂体系的化妆品，皮肤病学或药物制剂。

公开(公告)号：US20100279268A1

公开(公告)日：2010-11-04

申请号：US12679429

申请日：2008-09-24

申请人： Thomas Neumann ,  Anna V. Tourovskaia ,  Mark E. Fauver ,  Julia Oi Yan Yu

发明人： Thomas Neumann ,  Anna V. Tourovskaia ,  Mark E. Fauver ,  Julia Oi Yan Yu

IPC分类号： C12N5/02 ,  C12M1/00

CPC分类号： A61L27/3808 ,  A61L27/3886 ,  C12M21/08 ,  C12M25/14 ,  C12M29/10 ,  C12N5/0068 ,  C12N5/0691 ,  C12N2533/50

摘要： A method for creating networks of perfusable microvessels in vitro. Cells including cell types capable of sprouting are seeded 1300 into a channel in a matrix at to activate competency 1304 of the cells for sprouting as microvessels based on the seeding density. The matrix channel is perfused with medium to allow parent vessels to form and for viability 1324. The parent vessels and matrix are incubated and perfused to provide for sprouting of microvessels from parent vessels into the surrounding matrix 1328. The sprouting parent vessels are grown until network forms 1332.

摘要翻译： 一种在体外创建可灌注微血管网络的方法。 将包括能够发芽的细胞类型的细胞接种在基质中的通道中，以激活基于种子密度的作为微血管发芽的细胞的能力1304。 基质通道用培养基灌注以允许母体血管形成和存活力1324.将母体血管和基质温育并灌注以提供将微血管从亲本血管发芽到周围基质1328中。将发芽的母血管生长直至网络 表格1332。

公开(公告)号：US07690700B2

公开(公告)日：2010-04-06

申请号：US11835699

申请日：2007-08-08

申请人： Thomas Neumann

发明人： Thomas Neumann

IPC分类号： E05C19/10

CPC分类号： A47L15/4259 ,  E05C5/00 ,  E05C19/02 ,  Y10S292/61 ,  Y10T292/0914 ,  Y10T292/0926 ,  Y10T292/0932 ,  Y10T292/1047

摘要： A door latch device for a domestic electrical appliance, in particular for a dishwasher, has a frame (10) provided or to be provided on a first component of the domestic appliance, a latching unit (28) arranged so it can be displaced relative to the frame between an open position and a latched position for engagement with a closure system of a second component of the domestic appliance that can be moved relative to the first appliance component and is to be locked with respect thereto, and a latching spring assembly that pre-tensions the latching unit and which in the open position of the latching unit forces the unit into engagement with a blocking surface (24) that blocks relaxation of the latching spring assembly. According to one aspect of the invention a control member (52) that is separate from the latching unit and arranged so it can be moved relative thereto is provided, comprising an application system (64) for an actuating portion of the second appliance component and comprising an impact system for a block-cancelling effect on the latching unit. According to a further aspect the latching unit is formed by a one-piece latching body on which, in addition to a latching system (38) for engagement with the closure system of the second appliance component and a blocking system (50) for engagement with the blocking surface (24), supporting surfaces for the latching spring assembly are also arranged.

摘要翻译： 用于家用电器，特别是用于洗碗机的门闩装置具有设置或设置在家用电器的第一部件上的框架（10），闩锁单元（28）布置成使得其可以相对于 所述框架在打开位置和闩锁位置之间，用于与家用电器的第二部件的封闭系统接合，所述闭合系统可以相对于所述第一器具部件移动并且相对于所述第二部件被锁定;以及闩锁弹簧组件， 并且在闩锁单元的打开位置处，该单元迫使该单元与阻挡闭锁弹簧组件松弛的阻挡表面（24）接合。 根据本发明的一个方面，提供了一种与闩锁单元分离并布置成可相对于其移动的控制构件（52），包括用于第二器具部件的致动部分的应用系统（64），并且包括 用于对锁定单元进行块消除效果的冲击系统。 根据另一方面，闩锁单元由一体式闩锁体形成，除了用于与第二器具部件的闭合系统接合的闩锁系统（38）以及用于与 阻挡表面（24）也用于锁定弹簧组件的支撑表面。