Microfluidic system comprising an electrode arrangement and associated control method
    21.
    发明申请
    Microfluidic system comprising an electrode arrangement and associated control method 审中-公开
    微流体系统包括电极装置和相关联的控制方法

    公开(公告)号:US20070163883A1

    公开(公告)日:2007-07-19

    申请号:US10597674

    申请日:2005-02-03

    IPC分类号: B03C5/02

    摘要: The invention relates to a microfluidic system, in particular in a cell sorter, including a first carrier power supply (1) which is used to supply a first carrier flow having particles (4) suspended therein, a first carrier power output line (15) which is used to withdraw at least one part of the carrier flow having particles (4) suspended therein, a process chamber (3) which is used to examine, observe, manipulate and/or select the particle (4). The first carrier power supply (1) flows into the process chamber (3) when the first carrier power output line (15) is discharged from the process chamber (3). According to the invention, at least one second carrier power supply (2) flows into the process chamber (3) in order to supply a second carrier flow having particles (5) suspended therein. The invention also relates to a corresponding operational method.

    摘要翻译: 本发明涉及微流体系统,特别是在细胞分选机中,包括用于提供悬浮在其中的颗粒(4)的第一载体流的第一载体电源(1),第一载体功率输出线(15) 其用于抽出具有悬浮在其中的颗粒(4)的载体流的至少一部分,用于检查,观察,操纵和/或选择颗粒(4)的处理室(3)。 当第一载体动力输出管线(15)从处理室(3)排出时,第一载体电源(1)流入处理室(3)。 根据本发明,至少一个第二载体电源(2)流入处理室(3),以便提供具有悬浮在其中的颗粒(5)的第二载体流。 本发明还涉及相应的操作方法。

    Methods and devices for separting particles in a liquid flow
    22.
    发明申请
    Methods and devices for separting particles in a liquid flow 有权
    在液体流中分离颗粒的方法和装置

    公开(公告)号:US20060289341A1

    公开(公告)日:2006-12-28

    申请号:US10549886

    申请日:2004-03-17

    IPC分类号: B03C7/00 B03B5/00

    CPC分类号: B03C5/005

    摘要: Methods and devices for the separation of particles (20, 21, 22) in a compartment (30) of a fluidic microsystem (100) are described, in which the movement of a liquid (10) in which particles (20, 21, 22) are suspended with a predetermined direction of flow through the compartment (30), and the generation of a deflecting potential in which at least a part of the particles (20, 21, 22) is moved relative to the liquid in a direction of deflection are envisaged, whereby further at least one focusing potential is generated, so that at least a part of the particles is moved opposite to the direction of deflection relative to the liquid by dielectrophoresis under the effect of high-frequency electrical fields, and guiding of particles with different electrical, magnetic or geometric properties into different flow areas (11, 12) in the liquid takes place.

    摘要翻译: 描述了用于在流体微系统(100)的隔室(30)中分离颗粒(20,21,22)的方法和装置,其中液体(10)的运动,其中颗粒(20,21,22 )以预定的流动方向悬挂通过隔室(30),并产生偏转电位,其中至少一部分颗粒(20,21,22)在偏转方向上相对于液体移动 被设想为进一步产生至少一个聚焦电位,使得至少一部分颗粒在高频电场的作用下通过介电电泳相对于液体的偏转方向移动,并且引导颗粒 在不同的流动区域(11,12)中发生不同的电,磁或几何特性。

    Device and method for coupling lines to fluidic microsystems
    23.
    发明申请
    Device and method for coupling lines to fluidic microsystems 失效
    将线耦合到流体微系统的装置和方法

    公开(公告)号:US20060012167A1

    公开(公告)日:2006-01-19

    申请号:US10509190

    申请日:2003-03-25

    IPC分类号: F16L41/00

    CPC分类号: F16L37/05

    摘要: A coupling device (100), particularly for liquid-tight coupling of at least one liquid line (10) to a fluidic system (20), is described, which comprises: at least one sealing device (30), which is implemented to receive an end region (11) of the liquid line (10) and has a first sealing surface (31) for placement on an external surface (22) of the fluidic system in such a way that the end of the liquid line (10) is laterally enclosed by the first sealing surface (31) and points toward an opening (23) in the external surface (22), and a clamping device (40), using which the sealing device (30) may be pressed against the fluidic system (20), so that the first sealing surface (31) produces a liquid-tight connection with the external surface (22).

    摘要翻译: 描述了一种尤其用于至少一条液体管线(10)与流体系统(20)的液密耦合的联接装置(100),其包括:至少一个密封装置(30),其被实施为接收 液体管线(10)的端部区域(11),并且具有用于放置在流体系统的外表面(22)上的第一密封表面(31),使得液体管线(10)的端部为 由第一密封表面(31)横向包围并指向外表面(22)中的开口(23)的夹紧装置(40),密封装置(30)可以被压靠流体系统 20),使得第一密封表面(31)产生与外表面(22)的液密连接。

    Process and device for generating resonance phenomena in particle
suspensions
    24.
    发明授权
    Process and device for generating resonance phenomena in particle suspensions 失效
    用于在颗粒悬浮液中产生共振现象的方法和装置

    公开(公告)号:US6056861A

    公开(公告)日:2000-05-02

    申请号:US77334

    申请日:1998-07-27

    摘要: A method and a device for position and/or type-selective control of the position and/or change of position of suspended particles in a multielectrode system by the effect of polarization forces that are induced in the particles by alternating electric fields in the multielectrode system, which particles comprise biological or synthetic objects with dimensions essentially corresponding to those of biological cells or cell organelles, viruses or macromolecules, base on the fact that the multielectrode system forms with the particle suspension an electrical network, in which means of resonance are provided for creating a resonant increase or damping of the field strength of the alternating electric fields at certain frequencies in at least one locally demarcated region of the multielectrode system.

    摘要翻译: PCT No.PCT / EP96 / 05244 Sec。 371日期:1998年7月27日 102(e)1998年7月27日PCT PCT 1996年11月27日PCT公布。 出版物WO97 / 20210 日期:1997年6月5日在多电极系统中通过交替电致使粒子诱导的极化力的作用,位置和/或型式选择性地控制悬浮颗粒的位置和/或位置变化的方法和装置 所述多电极系统中的所述颗粒包含基本上对应于生物细胞或细胞器,病毒或大分子的尺寸的生物或合成物体,其基于所述多电极系统与所述粒子悬浮液形成电网, 提供谐振以在多电极系统的至少一个局部分界区域中产生在某些频率处的交变电场的场强的共振增加或阻尼。

    Method and device for aligning and storing in a given order moldings
having a tubular perforation
    25.
    发明授权
    Method and device for aligning and storing in a given order moldings having a tubular perforation 失效
    用于以给定的顺序对准和存储具有管状穿孔的模制品的方法和装置

    公开(公告)号:US4995779A

    公开(公告)日:1991-02-26

    申请号:US302164

    申请日:1989-01-25

    申请人: Torsten Muller

    发明人: Torsten Muller

    IPC分类号: B23Q7/18 B65G47/14 B65G47/256

    CPC分类号: B65G47/256

    摘要: "Method and device for aligning and storing in a given order moldings having a tubular perforation."Individual moldings (6) are introduced successively from above into a turbulence space above a receiving mandrel (5) profiled for reception in the perforation (7) in the molding (6). Each molding is subjected to an aligning air turbulence until the molding (6) has been aligned with its perforation (7) with respect to the receiving mandrel (5) in such a manner that the molding (6) falls onto the receiving mandrel (5) due to an air resistance decreasing as a result of the alignment. The receiving mandrel (5) then passes the molding (6) on to a deposition transport rail (19).

    摘要翻译: “用于以给定的顺序对准和存储具有管状穿孔的模制品的方法和装置”。将各个模制件(6)从上方连续地引入到接收心轴(5)上方的湍流空间中,该容纳心轴(5)被成形为用于在穿孔(7)中接收 成型(6)。 每个模制件经受对准的空气湍流,直到模制件(6)相对于接收心轴(5)已经与其穿孔(7)对准,使得模制件(6)落在接收心轴(5)上 )由于对准的结果导致空气阻力降低。 接收心轴(5)然后将模制件(6)传递到沉积输送轨道(19)上。