公开(公告)号：US12097492B2

公开(公告)日：2024-09-24

申请号：US17819201

申请日：2022-08-11

申请人： Jae Go Kwon

发明人： Jae Go Kwon

IPC分类号： B01L3/00 ,  B01L3/18 ,  C12M1/26 ,  F16H55/20 ,  F16H55/26

CPC分类号： B01L3/18 ,  C12M33/00 ,  F16H55/20 ,  F16H55/26

摘要： The laboratory device includes an elongated handle with ergonomic grips. The device has a center recess for a rod to slide or rotate. The blade head attaches at the distal end of the elongated handle. The rod has geared teeth that interact and mesh with the gears on the blade head allowing the user to manipulate the angle of the blade head via rod. The rod in the proximal position of the handle is disposed at an acute angle relative to the longitudinal axis of the handle such that the blade head and handle are positioned for insertion into and removal of a tissue culture vessel. When the rod is moved distally or rotated the blade head position is disposed perpendicularly, acute or obtusely in relationship to the longitudinal axes of the handle such that the blade head provides optimal raking opportunities for the device to collect cell colonies.

公开(公告)号：US12077736B2

公开(公告)日：2024-09-03

申请号：US14684401

申请日：2015-04-12

申请人： Dennis Steele

发明人： Dennis Steele

IPC分类号： C12M1/00 ,  C12M1/02 ,  C12M1/26

CPC分类号： C12M21/02 ,  C12M23/58 ,  C12M31/02 ,  C12M33/00 ,  C12M41/18 ,  C12M43/08 ,  Y02P20/59

摘要： An improved system of generating renewable energy is comprised of a specific configuration of mechanisms, materials, and processes that all function together as a single symbiotic system. In accordance with a preferred embodiment, the system cultivates aquatic biomass, then extracts triglycerides from said biomass. The extracted triglycerides are converted into biodiesel through transesterification. During the operation of the system, a continuous output of biofuel, thermal energy, steam, and electricity, is efficiently produced. These yields are precisely measured and repurposed as energy input at various points throughout system processes, thus resulting in a surplus output. Any embodiment of the disclosed system will generate a continuously renewable final product of biofuel and power.

公开(公告)号：US12054701B2

公开(公告)日：2024-08-06

申请号：US17224591

申请日：2021-04-07

申请人： NIKON CORPORATION ,  KYOTO UNIVERSITY

发明人： Tomoro Dan ,  Hiroaki Kii ,  Takayuki Uozumi ,  Yoshiko Sato ,  Shinsuke Yoshida

IPC分类号： C12M1/34 ,  C12M1/36 ,  C12N5/074 ,  C12M1/00 ,  C12M1/26

CPC分类号： C12M41/46 ,  C12M41/36 ,  C12M41/48 ,  C12N5/0696 ,  C12M31/10 ,  C12M33/00

摘要： A passage timing calculation device includes a processor and a memory encoded with instructions executed by the processor, wherein the instructions causing the processor to perform operations comprising calculating a time change in an area occupied by an extraction target region that is a region in which a striated pattern appears from a plurality of images of pluripotent stem cells captured at different times, detecting a change point of the time change in an area occupied by the extraction target region, and calculating a passage timing of the pluripotent stem cells on the basis of the change point.

公开(公告)号：US12024550B2

公开(公告)日：2024-07-02

申请号：US17672777

申请日：2022-02-16

申请人： CMC BIOLOGICS A/S

发明人： Mads Laustsen ,  Simon Bergmann

IPC分类号： C07K16/00 ,  B01D15/18 ,  B01D15/20 ,  B01D15/38 ,  B01D15/42 ,  C07K1/36 ,  C12M1/26 ,  G01N30/46 ,  G01N30/88

CPC分类号： C07K16/00 ,  B01D15/1864 ,  B01D15/1885 ,  B01D15/20 ,  B01D15/3804 ,  B01D15/424 ,  C07K1/36 ,  C12M33/00 ,  G01N30/468 ,  G01N30/88 ,  C07K2317/55 ,  C07K2317/622 ,  G01N2030/8831

摘要： Provided is a bioreactor arrangement for producing a biopolymer expressed by a cell and a continuous process for a capturing the biopolymer employing two chromatography units operated in series or independently.

公开(公告)号：US12018242B2

公开(公告)日：2024-06-25

申请号：US16956888

申请日：2018-12-21

申请人： Evologic Technologies GmbH

发明人： Markus Brillmann ,  Paul Krautwaschl ,  Wieland Reichelt ,  Christoph Herwig

IPC分类号： C12M1/33 ,  C12M1/00 ,  C12M1/06 ,  C12M1/12 ,  C12M1/26 ,  C12M1/34 ,  C12N5/04

CPC分类号： C12M45/02 ,  C12M25/16 ,  C12M27/02 ,  C12M29/06 ,  C12M33/00 ,  C12M41/00 ,  C12M41/26 ,  C12M41/32 ,  C12N5/04

摘要： The present invention relates to bioreactors for root organ cultures that enable large parts of the inoculation or biomass transfer, cultivation and harvest of the cultures to be performed outside of an aseptic environment. The present invention further relates to methods of producing and aseptically harvesting roots, and methods of producing root cultures using the aforementioned bioreactors alone or as part of an apparatus further comprising an inoculation vessel or at least one further bioreactor.

公开(公告)号：US12017228B2

公开(公告)日：2024-06-25

申请号：US16634126

申请日：2018-06-13

申请人： Sartorius Stedim Biotech GmbH

发明人： Isabelle Gay

IPC分类号： C12M3/00 ,  B01L3/00 ,  C12M1/00 ,  C12M1/26

CPC分类号： B01L3/563 ,  C12M23/28 ,  C12M23/40 ,  C12M23/46 ,  C12M27/18 ,  C12M33/00 ,  B01L2200/141 ,  B01L2400/00

摘要： Systems and a method for transferring chemical, pharmaceutical, and/or biological material into or out of a container are provided. One system comprises a disposable container having at least one port for accessing the interior of the container, the port comprising at least one connecting protrusion extending parallel to the container. The system further comprises a transfer interface connectable to the port. The transfer interface comprises a plate, and at least one connecting flange extending from the plate, the connecting flange to be arranged under the respective connecting protrusion to connect the transfer interface to the port, such that when the transfer interface is connected to the port the plate is parallel to a surface of the container.

公开(公告)号：US20240191204A1

公开(公告)日：2024-06-13

申请号：US18391053

申请日：2023-12-20

申请人： Cellino Biotech, Inc.

发明人： Matthias WAGNER ,  Suvi AIVIO ,  Mariangela AMENDUNI ,  Catherine PILSMAKER ,  Arnaldo PEREIRA ,  Ananya ZUTSHI ,  Anthia TOURE ,  Steven NAGLE ,  Ozge WHITING ,  George HARB ,  Matthew SULLIVAN ,  Maya BERLIN-UDI ,  Stefanie MORGAN ,  Nick SEAY ,  Sang LEE ,  Scott LURO

IPC分类号： C12N5/074 ,  B01L3/00 ,  B01L9/00 ,  C12M1/00 ,  C12M1/06 ,  C12M1/12 ,  C12M1/26 ,  C12M1/34 ,  C12M1/36 ,  C12M3/00 ,  C12N5/00 ,  G01N15/10 ,  G01N15/14 ,  G01N15/1429 ,  G01N15/1433 ,  G01N15/1434 ,  G06T7/00

CPC分类号： C12N5/0696 ,  B01L3/502715 ,  B01L3/502761 ,  B01L9/52 ,  C12M23/14 ,  C12M23/22 ,  C12M23/26 ,  C12M23/28 ,  C12M23/42 ,  C12M23/44 ,  C12M23/48 ,  C12M25/06 ,  C12M27/02 ,  C12M29/02 ,  C12M31/02 ,  C12M33/00 ,  C12M33/12 ,  C12M41/12 ,  C12M41/26 ,  C12M41/44 ,  C12M41/46 ,  C12M41/48 ,  C12M47/04 ,  C12N5/0081 ,  G01N15/1023 ,  G01N15/1429 ,  G01N15/1433 ,  G01N15/1434 ,  G06T7/0012 ,  G06T7/0016 ,  B01L2200/18 ,  B01L2300/0663 ,  B01L2300/0877 ,  C12M41/36 ,  G01N2015/1006 ,  G01N2015/1452 ,  G01N2015/1454 ,  G01N2015/1486 ,  G06T2207/10056 ,  G06T2207/10064 ,  G06T2207/20081 ,  G06T2207/30024 ,  G06T2207/30072

摘要： Disclosed herein are platforms, systems, and methods including a cell culture system that includes a cell culture container comprising a cell culture, the cell culture receiving input cells, a cell imaging subsystem configured to acquire images of the cell culture, a computing subsystem configured to perform a cell culture process on the cell culture according to the images acquired by the cell imaging subsystem, and a cell editing subsystem configured to edit the cell culture to produce output cell products according to the cell culture process.

公开(公告)号：US20240124829A1

公开(公告)日：2024-04-18

申请号：US18399336

申请日：2023-12-28

申请人： Copan Italia S.p.A.

发明人： Daniele Triva

IPC分类号： C12M1/36 ,  C12M1/00 ,  C12M1/22 ,  C12M1/26 ,  C12M1/34 ,  C12N1/20 ,  G01N35/00

CPC分类号： C12M41/48 ,  C12M23/10 ,  C12M23/50 ,  C12M23/52 ,  C12M33/00 ,  C12M41/06 ,  C12M41/46 ,  C12N1/20 ,  G01N35/00029 ,  G01N35/00732

摘要： An automatic processing device of culture plates including a support frame; a slide for removably housing a culture plate and movably mounted on the support frame selectively displaceable between a first loading position, a plurality of image-acquiring positions, and a first unloading position; a camera of a linear type, provided with a telecentric optic and a trilinear sensor, and arranged to acquire a multiplicity of linear images of corresponding linear portions of an upper surface of the culture plate, during the displacing of the slide; a first lighting device orientated such as to illuminate the linear portions of an upper surface of the culture plate; an advancing device of the slide configured such as to enable obtaining a constant and substantially vibration-free advancing speed of the slide in the image-acquiring zone; and an electronic control device of a functioning of the camera, of the lighting device and of the advancing device.

公开(公告)号：US11912970B2

公开(公告)日：2024-02-27

申请号：US16614174

申请日：2018-05-15

申请人： The University of Chicago

发明人： Ce Zhang ,  Savas Tay

IPC分类号： C12M3/06 ,  C12M1/00 ,  C12M1/02 ,  C12M1/26 ,  C12M1/34 ,  C12M1/36

CPC分类号： C12M23/16 ,  C12M23/34 ,  C12M23/40 ,  C12M27/00 ,  C12M29/00 ,  C12M33/00 ,  C12M41/32 ,  C12M41/48

摘要： Microfluidic devices, systems, and methods.

公开(公告)号：US20240060885A1

公开(公告)日：2024-02-22

申请号：US18385233

申请日：2023-10-30

申请人： Photothermal Spectroscopy Corp.

发明人： Craig Prater ,  Derek Decker ,  Roshan Shetty

IPC分类号： G01N21/3563 ,  G06T7/00 ,  G02B21/06 ,  G02B21/36 ,  C12M1/00 ,  C12M1/26 ,  C12M1/34 ,  C12M1/36 ,  C12N1/12 ,  H04N23/74 ,  H04N23/741

CPC分类号： G01N21/3563 ,  G06T7/97 ,  G02B21/06 ,  G02B21/365 ,  C12M21/02 ,  C12M29/00 ,  C12M29/04 ,  C12M29/22 ,  C12M33/00 ,  C12M39/00 ,  C12M41/12 ,  C12M41/26 ,  C12M41/34 ,  C12M41/36 ,  C12M41/44 ,  C12M41/48 ,  C12N1/12 ,  H04N23/74 ,  H04N23/741 ,  G01N2201/061 ,  G01N2201/062 ,  G06T2207/10048 ,  G06T2207/10056 ,  G06T2207/10152

摘要： Apparatuses and methods for microscopic analysis of a sample by simultaneously characterizing infrared absorption characteristics of a plurality of spatially resolved locations are described herein. These apparatuses and methods improve sampling times while collecting microscopic data regarding composition of a sample across a wide field.