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21.Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor 有权
标题翻译: 局部骨内施用骨形成剂和抗吸收剂及其装置公开(公告)号:US08895540B2
公开(公告)日:2014-11-25
申请号:US10723250
申请日:2003-11-26
申请人: Thomas M. DiMauro , Mohamed Attawia , Hassan Serhan , Melissa Grace , Michael Slivka , Thomas G. Ferro , Vivek N. Shenoy , Alonzo D. Cook , Scott Bruder
发明人: Thomas M. DiMauro , Mohamed Attawia , Hassan Serhan , Melissa Grace , Michael Slivka , Thomas G. Ferro , Vivek N. Shenoy , Alonzo D. Cook , Scott Bruder
IPC分类号: A01N45/00 , A61K45/06 , A61K33/42 , A61K38/39 , A61K31/565 , A61K39/395 , A61K38/18 , A61K31/566 , A61B17/34 , A61K9/00 , A61M5/145 , A61M5/142 , A61F2/30 , A61F2/28
CPC分类号: A61K33/42 , A61B17/3472 , A61F2002/2817 , A61F2002/30677 , A61K9/0004 , A61K31/565 , A61K31/566 , A61K38/1825 , A61K38/1875 , A61K38/39 , A61K39/395 , A61K45/06 , A61M5/14276 , A61M2005/14513 , A61K2300/00
摘要: This invention relates to local administration of a bone-forming agent and at least one anti-resorptive agent to treat osteoporosis and related disorders.
摘要翻译: 本发明涉及局部施用骨形成剂和至少一种抗再吸收剂来治疗骨质疏松症和相关疾病。
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22.Transdiscal administration of anti-TNFα antibodies and growth differentiation factors 有权
标题翻译: 反式TNFα抗体和生长分化因子的经半径给药公开(公告)号:US08877193B2
公开(公告)日:2014-11-04
申请号:US12290998
申请日:2008-11-05
申请人: Hassan Serhan , Mohamed Attawia , Thomas M. DiMauro , Sudhakar Kadiyala , David Urbahns , Scott Bruder
发明人: Hassan Serhan , Mohamed Attawia , Thomas M. DiMauro , Sudhakar Kadiyala , David Urbahns , Scott Bruder
IPC分类号: A61K39/00 , A61K39/395 , A61K38/17
CPC分类号: A61K35/28 , A61B5/055 , A61B17/7061 , A61K9/0012 , A61K9/0019 , A61K9/0085 , A61K35/32 , A61K38/17 , A61K38/1793 , A61K38/18 , A61K38/1841 , A61K38/1875 , A61K38/20 , A61K38/363 , A61K38/4833 , A61K39/395 , A61K39/3955 , A61K45/06 , A61K47/34 , C12Y304/21005 , G01N33/6869 , G01N2333/54
摘要: The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.
摘要翻译: 本发明涉及将高特异性细胞因子拮抗剂注射到患病的椎间盘中。
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公开(公告)号:US08273347B2
公开(公告)日:2012-09-25
申请号:US10714594
申请日:2003-11-14
CPC分类号: A61K35/19 , A61K35/28 , A61K35/32 , A61K35/33 , A61K38/1841 , A61K2300/00
摘要: The present invention relates to administering autologous uncultured cells into a diseased intervertebral disc.
摘要翻译: 本发明涉及将自体未培养的细胞施用于患病的椎间盘。
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24.Transdiscal administration of specific inhibitors of pro-inflammatory cytokines 有权
标题翻译: 跨时间给药促炎细胞因子的特异性抑制剂公开(公告)号:US20090175943A1
公开(公告)日:2009-07-09
申请号:US12291378
申请日:2008-11-07
申请人: Mohamed Attawia , Thomas M. DiMauro , Hassan Serhan , Sudhakar Kadiyala , David Urbahns , Scott Bruder
发明人: Mohamed Attawia , Thomas M. DiMauro , Hassan Serhan , Sudhakar Kadiyala , David Urbahns , Scott Bruder
IPC分类号: A61K9/10 , A61K39/395
CPC分类号: A61K35/28 , A61B5/055 , A61B17/7061 , A61K9/0012 , A61K9/0019 , A61K9/0085 , A61K35/32 , A61K38/17 , A61K38/1793 , A61K38/18 , A61K38/1841 , A61K38/1875 , A61K38/20 , A61K38/363 , A61K38/4833 , A61K39/395 , A61K39/3955 , A61K45/06 , A61K47/34 , C12Y304/21005 , G01N33/6869 , G01N2333/54
摘要: The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.
摘要翻译: 本发明涉及将高特异性细胞因子拮抗剂注射到患病的椎间盘中。
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公开(公告)号:US07429378B2
公开(公告)日:2008-09-30
申请号:US10610355
申请日:2003-06-30
申请人: Hassan Serhan , Thomas M. DiMauro , Mohamed Attawia , Sudhakar Kadiyala , David Urbahns , Scott Bruder , Laura J. Brown , Jeffrey C. Geesin
发明人: Hassan Serhan , Thomas M. DiMauro , Mohamed Attawia , Sudhakar Kadiyala , David Urbahns , Scott Bruder , Laura J. Brown , Jeffrey C. Geesin
IPC分类号: A61K35/00
CPC分类号: A61K38/1841 , A61K35/28 , A61K38/57 , A61K2300/00
摘要: The present invention relates to injecting a high affinity antagonist of MMPs into a diseased intervertebral disc.
摘要翻译: 本发明涉及将MMP的高亲和力拮抗剂注射到患病的椎间盘中。
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公开(公告)号:US20080213261A1
公开(公告)日:2008-09-04
申请号:US11881926
申请日:2007-07-30
申请人: Thomas M. DiMauro , Hassan Serhan , Mohamed Attawia , Sudhakar Kadiyala , David Urbahns , Scott Bruder
发明人: Thomas M. DiMauro , Hassan Serhan , Mohamed Attawia , Sudhakar Kadiyala , David Urbahns , Scott Bruder
IPC分类号: A61K39/395 , A61K35/00 , A61P19/00 , A61K35/12
CPC分类号: A61K35/28 , A61B5/055 , A61B17/7061 , A61K9/0012 , A61K9/0019 , A61K9/0085 , A61K35/32 , A61K38/17 , A61K38/1793 , A61K38/18 , A61K38/1841 , A61K38/1875 , A61K38/20 , A61K38/363 , A61K38/4833 , A61K39/395 , A61K39/3955 , A61K45/06 , A61K47/34 , C12Y304/21005 , G01N33/6869 , G01N2333/54
摘要: The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.
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公开(公告)号:US20070282300A1
公开(公告)日:2007-12-06
申请号:US11422222
申请日:2006-06-05
申请人: Mohamed Attawia , Cynthia Lee , Hassan Serhan , Michael O'Neil
发明人: Mohamed Attawia , Cynthia Lee , Hassan Serhan , Michael O'Neil
CPC分类号: A61B17/0218 , A61B17/3415 , A61B2017/00026 , A61B2017/00039 , A61B2017/00261 , A61B2017/0262 , A61F2/4611 , A61F2002/444 , A61F2002/4627
摘要: A pre-assembled, telescoping needle system comprising an outer needle surrounding a finer gauge needle which, after percutaneous penetration by the outer needle, extends to penetrate the intervertebral disc into which the injectable is to be delivered.
摘要翻译: 预组装的伸缩针系统,其包括围绕细针规的针的外针,所述外针经由外针的经皮穿透之后延伸以穿透待注射器将被输送到的椎间盘。
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公开(公告)号:US08333960B2
公开(公告)日:2012-12-18
申请号:US12291016
申请日:2008-10-31
CPC分类号: A61K35/19 , A61K35/28 , A61K35/32 , A61K35/33 , A61K38/1841 , A61K2300/00
摘要: The present invention relates to administering autologous uncultured cells into a diseased intervertebral disc.
摘要翻译: 本发明涉及将自体未培养的细胞施用于患病的椎间盘。
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公开(公告)号:US08067397B2
公开(公告)日:2011-11-29
申请号:US12454200
申请日:2009-05-14
申请人: Mohamed Attawia , Thomas M. DiMauro , Hassan Serhan , Sudhakar Kadiyala , David Urbahns , Gregory Collins , Laura J. Brown , Jeffrey C. Geesin
发明人: Mohamed Attawia , Thomas M. DiMauro , Hassan Serhan , Sudhakar Kadiyala , David Urbahns , Gregory Collins , Laura J. Brown , Jeffrey C. Geesin
CPC分类号: A61K31/65 , A61K38/20 , A61K45/06 , A61K2300/00
摘要: The present invention relates to administering a doxycycline compound into a diseased intervertebral disc.
摘要翻译: 本发明涉及将多西环素化合物给予患病的椎间盘。
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公开(公告)号:US20090324558A1
公开(公告)日:2009-12-31
申请号:US12454200
申请日:2009-05-14
申请人: Mohamed Attawia , Thomas M. DiMauro , Hassan Serhan , Sudhakar Kadiyala , David Urbahns , Gregory Collins , Laura J. Brown , Jeffrey C. Geesin
发明人: Mohamed Attawia , Thomas M. DiMauro , Hassan Serhan , Sudhakar Kadiyala , David Urbahns , Gregory Collins , Laura J. Brown , Jeffrey C. Geesin
CPC分类号: A61K31/65 , A61K38/20 , A61K45/06 , A61K2300/00
摘要: The present invention relates to administering a doxycycline compound into a diseased intervertebral disc.
摘要翻译: 本发明涉及将多西环素化合物给予患病的椎间盘。
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