APPARATUS, SYSTEM, AND METHOD FOR CYCLE IMPROVEMENTS
    21.
    发明申请
    APPARATUS, SYSTEM, AND METHOD FOR CYCLE IMPROVEMENTS 有权
    装置,系统和周期改进方法

    公开(公告)号:US20120238410A1

    公开(公告)日:2012-09-20

    申请号:US13048860

    申请日:2011-03-15

    摘要: A cycle with tapered drivetrain connections. The cycle includes a frame, a crank rotatably connected to the frame, and a driven wheel rotatably connected to the frame. The crank includes a crank arm and a crank spindle rotatably connected to the frame and non-rotatably connected to the crank arm. The crank spindle includes a crank mating surface to interface with the crank arm. The diameter of the crank spindle continuously decreases along at least a portion of the crank mating surface in a lateral direction. The crank arm includes a crank bore to interface with the crank mating surface. At least a portion of the crank bore has a diameter that continuously decreases in lateral direction. At least a portion of the crank bore taper has a taper rate and diameter equal to a taper rate and diameter of at least a portion of the crank spindle taper.

    摘要翻译: 具有锥形传动系连接的循环。 该循环包括框架,可旋转地连接到框架的曲柄和可旋转地连接到框架的从动轮。 曲柄包括可旋转地连接到框架并且不可旋转地连接到曲柄臂的曲柄臂和曲柄心轴。 曲柄轴包括与曲柄臂相接的曲柄配合表面。 曲柄轴的直径沿曲柄配合面的至少一部分沿横向方向连续地减小。 曲柄臂包括与曲柄配合表面相接的曲柄孔。 曲柄孔的至少一部分具有在横向方向上连续减小的直径。 曲柄孔锥度的至少一部分具有等于曲柄轴锥度的至少一部分的锥度速率和直径的锥度速率和直径。

    Method of testing a surgical system
    23.
    发明申请
    Method of testing a surgical system 有权
    检查手术系统的方法

    公开(公告)号:US20080006096A1

    公开(公告)日:2008-01-10

    申请号:US11167646

    申请日:2005-06-27

    IPC分类号: G01F15/07

    摘要: A method of testing a surgical system that takes advantage of the fact that in a balanced irrigation/aspiration system (inflow≧outflow) the duration of the aspiration pressure recovery to the irrigation fluid source pressure immediately following pump stop is independent of pump run time. This method provides a more reliable way of detecting restricted irrigation flow configurations not detectable by the current methods, such as marginal irrigation flow cases that could potentially lead to surgical complications (e.g. chamber collapse during post-occlusion break surge).

    摘要翻译: 一种测试手术系统的方法,其利用在平衡灌溉/抽吸系统(流入=流出)中的吸入压力恢复到泵停止之后的冲洗液源压力的持续时间与泵运行时间无关的事实 。 该方法提供了一种更可靠的方法来检测目前的方法无法检测到的限制性灌溉流动结构,例如可能导致手术并发症的边缘灌流流程病例(例如在闭塞后突发期间腔室崩溃)。

    Combination dehydrator, dry return air and condensed water generator/dispenser
    24.
    发明申请
    Combination dehydrator, dry return air and condensed water generator/dispenser 审中-公开
    组合脱水机,干式回风和冷凝水发生器/分配器

    公开(公告)号:US20070175063A1

    公开(公告)日:2007-08-02

    申请号:US11346110

    申请日:2006-02-02

    IPC分类号: F25D17/06 F26B3/00

    CPC分类号: F26B21/086 F26B21/001

    摘要: A portable, combination dehydrator, dry return air and condensed water generator/dispenser configured to reduce the humidity in a dry storage unit. In one embodiment, a system draws intake air from the dry storage unit across the condenser of a heat exchanger and condenses water from the air, collecting the water in a storage tank. The dried return air is ducted into the dry storage unit. In one embodiment, the source of the intake air may be selected from either the dry storage unit or an alternative source (e.g., outside air.) The selection of the intake air source may be based on the humidity of the air (e.g., if the humidity of the air in the dry storage unit is above a threshold, the dry storage unit is selected.) If both of the alternate sources of intake air have humidities below a threshold level, operation of the system may be suspended.

    摘要翻译: 便携式组合脱水器,干式回风和冷凝水发生器/分配器,配置为减少干燥存储单元中的湿度。 在一个实施例中,系统从干燥储存单元抽取来自热交换器的冷凝器的进气,并将来自空气的水汇集在储存罐中。 干燥的返回空气被导入干燥储存单元。 在一个实施例中,进气的源可以选自干燥储存单元或替代源(例如,外部空气)。进气空气源的选择可以基于空气的湿度(例如,如果 干燥存储单元中的空气的湿度高于阈值,则选择干燥储存单元。)如果两个替代的进气源具有低于阈值水平的湿度,则系统的操作可能被暂停。

    Materials and methods for gene therapy
    27.
    发明授权
    Materials and methods for gene therapy 有权
    基因治疗的材料和方法

    公开(公告)号:US06461606B1

    公开(公告)日:2002-10-08

    申请号:US09299141

    申请日:1999-04-23

    IPC分类号: A01N6300

    摘要: The subject invention concerns materials and methods for gene therapy. One aspect of the invention pertains to vectors which can be used to effect genetic therapy in animals or humans having genetic disorders where expression of high levels of a protein of interest are required to treat or correct the disorder. The subject invention also pertains to methods for treating animals or humans in need of gene therapy to treat or correct a genetic disorder. The materials and methods of the invention can be used to provide therapeutically effective levels of a protein that is non-functional, or that is absent or deficient in the animal or human to be treated. In one embodiment, the materials and methods can be used to treat alpha-1-antitrypsin deficiency.

    摘要翻译: 本发明涉及用于基因治疗的材料和方法。 本发明的一个方面涉及可用于在具有遗传障碍的动物或人类中进行遗传治疗的载体,其中高水平的感兴趣的蛋白质的表达需要治疗或纠正该病症。 本发明还涉及用于治疗需要基因治疗的动物或人的治疗或纠正遗传病症的方法。 本发明的材料和方法可用于提供治疗有效水平的蛋白质,其是非功能性的,或者不存在或缺乏待处理的动物或人类。 在一个实施方案中,材料和方法可用于治疗α-1-抗胰蛋白酶缺乏症。

    Apparatus, system, and method for cycle improvements
    30.
    发明授权
    Apparatus, system, and method for cycle improvements 有权
    用于循环改进的装置,系统和方法

    公开(公告)号:US09327799B2

    公开(公告)日:2016-05-03

    申请号:US13048860

    申请日:2011-03-15

    摘要: A cycle with tapered drivetrain connections. The cycle includes a frame, a crank rotatably connected to the frame, and a driven wheel rotatably connected to the frame. The crank includes a crank arm and a crank spindle rotatably connected to the frame and non-rotatably connected to the crank arm. The crank spindle includes a crank mating surface to interface with the crank arm. The diameter of the crank spindle continuously decreases along at least a portion of the crank mating surface in a lateral direction. The crank arm includes a crank bore to interface with the crank mating surface. At least a portion of the crank bore has a diameter that continuously decreases in lateral direction. At least a portion of the crank bore taper has a taper rate and diameter equal to a taper rate and diameter of at least a portion of the crank spindle taper.

    摘要翻译: 具有锥形传动系连接的循环。 该循环包括框架,可旋转地连接到框架的曲柄和可旋转地连接到框架的从动轮。 曲柄包括可旋转地连接到框架并且不可旋转地连接到曲柄臂的曲柄臂和曲柄心轴。 曲柄轴包括与曲柄臂相接的曲柄配合表面。 曲柄轴的直径沿曲柄配合面的至少一部分沿横向方向连续地减小。 曲柄臂包括与曲柄配合表面相接的曲柄孔。 曲柄孔的至少一部分具有在横向方向上连续减小的直径。 曲柄孔锥度的至少一部分具有等于曲柄轴锥度的至少一部分的锥度速率和直径的锥度速率和直径。