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公开(公告)号:US09504563B2
公开(公告)日:2016-11-29
申请号:US14164764
申请日:2014-01-27
Applicant: Edwards Lifesciences Corporation
Inventor: Rafael Pintor , Michael J. Scott , Thomas Chien , Harvey H. Chen , August R. Yambao , Lawrence J. Farhat , Andrew Phung , William C. Brunnett , Carey L. Cristea , Sara M. Walls , Kevin W. Zheng , Faisal Kalam , Qinggang Zeng
IPC: A61F2/24
CPC classification number: A61F2/2433 , A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2220/005 , A61F2220/0075 , A61F2220/0083 , A61F2230/0067 , A61F2250/0018 , A61F2250/0039 , A61F2250/0048 , A61F2250/006
Abstract: A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps.
Abstract translation: 提供了一种快速连接的心脏瓣膜假体,可以在手术过程中快速方便地植入。 心脏瓣膜包括基本上不可膨胀的,不可压缩的人造瓣膜和可塑性可扩张的框架,从而使得能够在没有缝线的情况下连接到环形空间。 可以提供少量的导向缝线用于主动脉瓣取向。 假体瓣膜可以是具有连接框架的缝合环的市售阀。 框架可以从锥形展开形状扩展到圆锥形扩展形状,并且可以包括连接在轴向延伸柱之间的网状支柱。 一种用于部署的系统和方法包括一体式手柄轴和球囊导管。 与心脏瓣膜一起存储阀保持器,并且手柄轴容易地附接到其上以改善阀门准备步骤。
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公开(公告)号:US20150216660A1
公开(公告)日:2015-08-06
申请号:US14685489
申请日:2015-04-13
Applicant: Edwards Lifesciences Corporation
Inventor: Rafael Pintor , Mark Chau , Travis Oba , August R. Yambao , Louis A. Campbell , Tammy Huntley , Qinggang Zeng , Carey L. Cristea , Faisal Kalam
IPC: A61F2/24
CPC classification number: A61F2/2427 , A61F2/2409 , A61F2/2418 , A61F2/2433 , A61F2/2439 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2220/005 , A61F2220/0075 , A61F2220/0083 , A61F2230/005 , A61F2250/006
Abstract: A quick-connect heart valve prosthesis that can be quickly and easily implanted is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable coupling stent, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the coupling stent attached thereto. The coupling stent may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes a hollow two-piece handle through which a balloon catheter passes. A valve holder is stored with the heart valve and the handle easily attaches thereto to improve valve preparation steps.
Abstract translation: 提供了可以快速且容易地植入的快速连接的心脏瓣膜假体。 心脏瓣膜包括基本上不可膨胀的不可压缩的人造瓣膜和塑性可扩张的联接支架,从而使得能够在不缝合的情况下连接到环形空间。 可以提供少量的导向缝线用于主动脉瓣取向。 假体瓣膜可以是具有连接有联接支架的缝合环的市售阀。 联接支架可以从锥形展开形状扩展到圆锥形膨胀形状,并且可以包括连接在轴向延伸柱之间的腹板状支柱。 用于展开的系统和方法包括气球导管通过的中空两件式手柄。 与心脏瓣膜一起存储阀保持器,并且手柄容易地附接到其上以改善阀门准备步骤。
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公开(公告)号:US20250064586A1
公开(公告)日:2025-02-27
申请号:US18948281
申请日:2024-11-14
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Derrick Johnson , Van Huynh , Qinggang Zeng
IPC: A61F2/24
Abstract: A prosthetic heart valve for implant in a human. The valve includes a wireform with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area. Each leaflet may drape over the top of the wireform in the cusp area, but have tabs that each extend underneath the wireform at the commissure posts to be secured along with a tab of an adjacent leaflet. The prosthetic heart valve may also be a dual-wire wireform, with the leaflets sandwiched therebetween. One wireform may be larger than the other, with the leaflets extending over the smaller wireform. The smaller wireform may have commissures that bend radially outward from the larger wireform to provide structure to which the leaflet tabs attach.
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公开(公告)号:US20230293294A1
公开(公告)日:2023-09-21
申请号:US18324900
申请日:2023-05-26
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Brian S. Conklin , Qinggang Zeng
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2433 , A61F2210/0004 , A61F2210/0057 , A61F2220/0075 , A61F2230/0052 , A61F2230/0054 , A61F2230/0067 , A61F2250/001 , A61F2250/0012 , A61F2250/0018 , A61F2250/0021 , A61F2250/0039 , A61F2250/0048 , A61F2250/0089
Abstract: A hybrid prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be expanded post implant in order to receive and/or support an expandable prosthetic heart valve therein (a valve-in-valve procedure). The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible for delivery and expandable post-implant to facilitate a valve-in-valve procedure.
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公开(公告)号:US11690714B2
公开(公告)日:2023-07-04
申请号:US16914255
申请日:2020-06-26
Applicant: Edwards Lifesciences Corporation
Inventor: Brian S. Conklin , Qinggang Zeng
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2433 , A61F2210/0004 , A61F2210/0057 , A61F2220/0075 , A61F2230/0052 , A61F2230/0054 , A61F2230/0067 , A61F2250/001 , A61F2250/0012 , A61F2250/0018 , A61F2250/0021 , A61F2250/0039 , A61F2250/0048 , A61F2250/0089
Abstract: A hybrid prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be expanded post implant in order to receive and/or support an expandable prosthetic heart valve therein (a valve-in-valve procedure). The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible for delivery and expandable post-implant to facilitate a valve-in-valve procedure.
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公开(公告)号:US11654020B2
公开(公告)日:2023-05-23
申请号:US16666331
申请日:2019-10-28
Applicant: Edwards Lifesciences Corporation
Inventor: Brian S. Conklin , Qinggang Zeng , Myron Howanec, Jr. , Grace Myong Kim
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2210/0057 , A61F2220/0075 , A61F2230/0069 , A61F2250/001 , A61F2250/006 , A61F2250/0018 , A61F2250/0048 , A61F2250/0097
Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible to a limited degree for delivery and expandable post-implant to facilitate valve-in-valve (ViV) procedures. The hybrid heart valves eliminate earlier structural bands, which both reduces manufacturing time and facilitates ViV procedures.
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公开(公告)号:US20210077255A1
公开(公告)日:2021-03-18
申请号:US17067618
申请日:2020-10-09
Applicant: Edwards Lifesciences Corporation
Inventor: Rafael Pintor , Mark Chau , Travis Zenyo Oba , August R. Yambao , Louis A. Campbell , Tammy Huntley , Qinggang Zeng , Carey L. Cristea , Faisal Kalam
IPC: A61F2/24
Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.
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公开(公告)号:US10722358B2
公开(公告)日:2020-07-28
申请号:US16056252
申请日:2018-08-06
Applicant: Edwards Lifesciences Corporation
Inventor: Rafael Pintor , Michael J. Scott , Thomas H. Chien , Harvey H. Chen , August R. Yambao , Lawrence J. Farhat , Andrew Phung , William C. Brunnett , Carey L. Cristea , Sara M. Walls , Kevin W. Zheng , Faisal Kalam , Qinggang Zeng
IPC: A61F2/24
Abstract: A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps.
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公开(公告)号:US10441415B2
公开(公告)日:2019-10-15
申请号:US14488728
申请日:2014-09-17
Applicant: Edwards Lifesciences Corporation
Inventor: Derrick Johnson , Van Le Huynh , Qinggang Zeng
IPC: A61F2/24
Abstract: A prosthetic heart valve for implant in a human. The valve includes a wireform with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area. Each leaflet may drape over the top of the wireform in the cusp area, but have tabs that each extend underneath the wireform at the commissure posts to be secured along with a tab of an adjacent leaflet. The prosthetic heart valve may also be a dual-wire wireform, with the leaflets sandwiched therebetween. One wireform may be larger than the other, with the leaflets extending over the smaller wireform. The smaller wireform may have commissures that bend radially outward from the larger wireform to provide structure to which the leaflet tabs attach.
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公开(公告)号:US20190167422A1
公开(公告)日:2019-06-06
申请号:US16270849
申请日:2019-02-08
Applicant: Edwards Lifesciences Corporation
Inventor: Jessica Guttenberg , Da-Yu Chang , Derrick Johnson , Brian S. Conklin , Qinggang Zeng , Myron Howanec, JR. , Grace Myong Kim
IPC: A61F2/24
Abstract: A prosthetic heart valve configured to replace a native heart valve and for post-implant expansion and having a valve-type indicator thereon visible from outside the body post-implant. The indicator communicates information about the valve, such as the size or orifice diameter of the valve, and/or that the valve has the capacity for post-implant expansion. The indicator can be an alphanumeric symbol or other symbol or combination of symbols that represent information about the characteristics of the valve such as the valve size. The capacity for post-implant expansion facilitates a valve-in-valve procedure, where the valve-type indicator conveys information to the surgeon about whether the implanted valve is suitable for the procedure and informs the choice of the secondary valve.
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