公开(公告)号：US10918473B2

公开(公告)日：2021-02-16

申请号：US16036190

申请日：2018-07-16

Applicant: Edwards Lifesciences Corporation

Inventor： Noam Nir ,  Carmel Peleg ,  Tomer Saar ,  Alexander Barash ,  David Maimon

IPC: A61F2/24 ,  A61F2/00 ,  B21D39/04 ,  A61F2/95

Abstract: Disclosed herein is a storage container for an expandable prosthetic heart valve that crimps the valve upon opening the container and removal of the valve from the container. The container includes a housing sized to receive the heart valve in its expanded configuration and a crimping mechanism. The crimping mechanism is incorporated into the container and engages the heart valve so as to operably convert the heart valve from its expanded configuration to its smaller crimped configuration upon opening the container and removing the valve.

公开(公告)号：US20200297482A1

公开(公告)日：2020-09-24

申请号：US16813637

申请日：2020-03-09

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Boaz Manash ,  Eyal Leiba ,  Ziv Yohanan ,  Yair A. Neumann ,  Anatoly Dvorsky ,  Jonathan Bar-Or ,  Oren Cohen ,  Ofir Witzman ,  Liron Tayeb ,  Elazar Levi Schwarcz ,  Noam Miller ,  Tomer Saar

IPC: A61F2/24

Abstract: An assembly can comprise a radially expandable and compressible annular frame, at least one linear actuator assembly coupled to the frame and at least one locking mechanism coupled to the frame. The linear actuator can be configured to apply a distally directed force and/or a proximally directed force to the frame to radially expand or compress the frame. The locking mechanism can comprise a first sleeve member connected to the frame at a first location, a second sleeve member having internal threads and being connected to the frame at a second location, and a first screw configured to engage the internal threads of the second sleeve member to retain the frame in a radially expanded state.

公开(公告)号：US20190069996A1

公开(公告)日：2019-03-07

申请号：US16119317

申请日：2018-08-31

Applicant: Edwards Lifesciences Corporation

Inventor： Tomer Saar ,  Hanoch Cohen-Tzemach ,  Nadav Ben Zaken

IPC: A61F2/24

Abstract: A prosthetic valve having a frame, a leaflet structure having leaflets forming a primary valve mounted inside the frame, and at least one secondary valve is disclosed. The secondary valve can have a valve element with stationary portion and a detached portion, and at least one aperture in at least one leaflet. The secondary valve can be formed by a portion of at least one leaflet.

公开(公告)号：US20180303613A1

公开(公告)日：2018-10-25

申请号：US15956031

申请日：2018-04-18

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Noam Nir ,  Tomer Saar

IPC: A61F2/24

CPC classification number: A61F2/2454 ,  A61F2/243

Abstract: A method for improving leaflet prolapse and/or valve regurgitation associated with a heart valve involves delivering a spacer device into a ventricle of a heart using a delivery system comprising a catheter, fixing the spacer device to a wall of the ventricle, expanding the spacer device to reposition a papillary muscle disposed in the ventricle away from the wall, the papillary muscle being connected to a leaflet of an atrioventricular heart valve via chordae tendineae, and releasing the spacer device from the catheter.

公开(公告)号：US20250090315A1

公开(公告)日：2025-03-20

申请号：US18965594

申请日：2024-12-02

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Liron Tayeb ,  Eran Goldberg ,  David Maimon ,  Adi Carmi ,  Arie Tylis ,  Tomer Saar ,  Anatoly Dvorsky

IPC: A61F2/24 ,  A61F2/88 ,  A61F2/90

Abstract: A docking station includes an expandable frame configured to conform to an interior shape of a blood vessel when expanded inside the blood vessel, wherein the frame includes an annular outer wall formed from at least one annular stent segment connected to a plurality of spring elements circumferentially spaced around the at least one annular stent segment.

公开(公告)号：US12053601B2

公开(公告)日：2024-08-06

申请号：US17111924

申请日：2020-12-04

Applicant: Edwards Lifesciences Corporation

Inventor： Tomer Saar ,  Michael Bukin ,  Dudu Haimovich ,  Roee Haimovich ,  Ohad Yakobovitch

IPC: A61M39/22 ,  A61F2/24 ,  A61M25/10 ,  A61F2/958 ,  A61M5/31 ,  A61M5/315

CPC classification number: A61M25/10182 ,  A61F2/2433 ,  A61M25/10186 ,  A61M39/22 ,  A61F2/958 ,  A61M2005/3128 ,  A61M2005/31598

Abstract: Disclosed herein are inflators and methods of using the inflators for inflating inflatable devices, such as balloons, used in medical procedures. Such procedures include angioplasty and the transcatheter delivery of prosthetic heart valves and stents. The inflators overcome the resistances typically generated during such procedures and reduces the force required to fully inflate the balloon.

公开(公告)号：US20230310150A1

公开(公告)日：2023-10-05

申请号：US18207822

申请日：2023-06-09

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Alexander Barash ,  Yair A. Neumann ,  Tomer Saar ,  Ziv Yohanan ,  Noam Nir

IPC: A61F2/24 ,  A61F2/844 ,  A61F2/95

CPC classification number: A61F2/2418 ,  A61F2/243 ,  A61F2/2439 ,  A61F2/844 ,  A61F2002/9511 ,  A61F2/9517 ,  A61F2/2436

Abstract: In one embodiment, a method of assembling a prosthetic valve can comprise forming a radially expandable and compressible frame by pivotally joining together a plurality of struts without requiring individual rivets. In some embodiments, the frame is formed by interweaving the struts, which can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In other embodiments, separate hinges are provided to interconnect the struts. In still other embodiments, separate flanged rivets are provided to connect the struts.

公开(公告)号：US20220287838A1

公开(公告)日：2022-09-15

申请号：US17829769

申请日：2022-06-01

Applicant: Edwards Lifesciences Corporation

Inventor： Oren Cohen ,  Tomer Saar ,  Elazar Levi Schwarcz ,  Ofir Witzman ,  Eitan Atias ,  Noam Miller ,  Eran Goldberg ,  Yair A. Neumann

IPC: A61F2/24 ,  A61F2/95

Abstract: A delivery apparatus for implanting a prosthetic valve includes a handle, a first shaft, a plurality of actuation shafts, and a control mechanism. The first shaft has one or more lumens extending from the first end portion to the second end portion. The actuation shafts each have a proximal end portion and a distal end portion, and the actuation shafts extend through the one or more lumens of the first shaft. The control mechanism is coupled to the actuation shafts and to the handle. The control mechanism is configured such that the actuation shafts can move axially relative to each other in a first operational mode and such that the actuation shafts can be moved axially simultaneously in a second operational mode. Additionally or alternatively, the first shaft can include a plurality of helical lumens configured for receiving the actuation shafts.

公开(公告)号：US11273031B2

公开(公告)日：2022-03-15

申请号：US16799741

申请日：2020-02-24

Applicant: Edwards Lifesciences Corporation

Inventor： Tomer Saar ,  Michael Bukin ,  Elena Sherman ,  Alexander Barash ,  Yana Mayatskaya

IPC: A61F2/24

Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame including a plurality of angled strut members, and a skirt member secured to the frame. The skirt member includes a plurality of extension portions wrapped around at least one strut member adjacent the extension portions. The prosthetic valve further includes a cord member threaded through at least a portion of the plurality of extension portions to secure the skirt member to the at least one strut member.

公开(公告)号：US20210282922A1

公开(公告)日：2021-09-16

申请号：US17337711

申请日：2021-06-03

Applicant: Edwards Lifesciences Corporation

Inventor： Hanoch Cohen-Tzemach ,  Tamir S. Levi ,  Yair A. Neumann ,  Tomer Saar ,  Gregory Rinberg

IPC: A61F2/24

Abstract: A radially expandable prosthetic valve can comprise an annular frame, at least one expansion mechanism and a cord. The annular frame can be radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration. The expansion mechanism can comprise a first member attached to the frame at a first location and a second member attached to the frame at a second location axially spaced from the first location. The cord can extend at least partially along the expansion mechanism in a first direction, be reeved around a portion of the second member, and extend at least partially along the expansion mechanism in a second direction opposite the first direction. Applying a proximally directed force to a first portion of the cord can cause the second member to move relative to the first member, which can cause the frame to foreshorten axially and expand radially.