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公开(公告)号:US20240081981A1
公开(公告)日:2024-03-14
申请号:US18352977
申请日:2023-07-14
发明人: Liron Tayeb , Ilan Tamir
IPC分类号: A61F2/24
CPC分类号: A61F2/2409 , A61F2/2415 , A61F2/2418 , A61F2/24 , A61F2/2412 , A61F2220/0075 , A61F2230/0091 , A61F2250/006 , A61F2250/0069
摘要: A prosthetic heart valve includes a radially expandable and collapsible frame with an inflow end including a plurality of inflow apices and an outflow end including a plurality of outflow apices. A plurality of valve leaflets are positioned in the frame and configured to control blood flow through the prosthetic heart valve. A covering is disposed around the frame. The covering has an inflow end portion having an inflow edge and an outflow end portion having an outflow edge. The inflow end portion of the covering is disposed over the inflow apices of the frame such that the inflow edge of the covering is inside the frame. The outflow end portion of the covering is disposed over the outflow apices of the frame such that the outflow edge of the covering is inside the frame, and the covering covers an entire outer surface of the frame.
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公开(公告)号:US20230255770A1
公开(公告)日:2023-08-17
申请号:US18138651
申请日:2023-04-24
发明人: David Maimon , Liron Tayeb , Eran Goldberg
CPC分类号: A61F2/2439 , A61F2/2433 , A61F2/2427 , A61M25/0023 , A61M2025/0024 , A61F2/9517
摘要: The active introducer sheath systems disclosed herein are expanded by activating a translation mechanism at the handle. The sheath has an inner cylindrical structure of comingled fixed and mobile elongate rods bound together by an attachment line. Activating the translation mechanism causes the mobile rods to move axially with respect to the fixed rods, changing the internal tension in the attachment line. Increased tension draws the fixed and mobile rods closer together, decreasing the diameter of the cylindrical structure. Decreased tension in the attachment line enables the fixed and mobile rods to move apart, increasing the diameter of the cylindrical structure. A prosthetic device, such as a prosthetic heart valve, can be routed through the expanded sheath and to the implantation site. During implantation, the sheath can be contracted back to its original outer diameter, and expanded again for retrieval of the delivery apparatus.
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公开(公告)号:US20220280287A1
公开(公告)日:2022-09-08
申请号:US17824411
申请日:2022-05-25
发明人: David Maimon , Boaz Manash , Eyal Leiba , Ziv Yohanan , Yair A. Neumann , Anatoly Dvorsky , Jonathan Bar-Or , Oren Cohen , Ofir Witzman , Liron Tayeb , Elazar Levi Schwarcz , Noam Miller , Tomer Saar
IPC分类号: A61F2/24
摘要: An assembly can comprise a prosthetic valve comprising a radially expandable and compressible frame and a rotatable screw connected to the frame, where the screw comprises a screw head having an annular bore with internal threads, and where the screw is rotatable to radially expand the frame. The assembly further comprises a delivery apparatus releasably coupled to the screw, the delivery apparatus comprising a first shaft and a first head disposed at an end of the first shaft, the first head comprising external threads configured to engage with the internal threads of the screw head, and a second shaft that is coaxial with and surrounds the first shaft, the second shaft comprising a second head disposed at an end of the second shaft. The second head is configured to releasably engage with an exterior surface of the screw head and rotate the screw.
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公开(公告)号:US20220226110A1
公开(公告)日:2022-07-21
申请号:US17657732
申请日:2022-04-01
发明人: Liron Tayeb , Eran Goldberg , David Maimon , Adi Carmi , Arie Tylis , Ralph Schneider , Mohammad Jafari , Hengchu Cao , Eitan Atias
IPC分类号: A61F2/24
摘要: An expandable docking station includes an annular valve seat having an end, an annular outer wall comprising struts disposed around the valve seat, and links that connect the end of the annular valve seat to the annular outer wall. Each of the links extends from the struts of the annular outer wall directly toward a longitudinal axis that runs longitudinally through a center of the docking station, and to a corresponding one of a plurality of circumferentially spaced axially extending legs at least partially defining the annular valve seat. The outer wall is configured to conform to an interior shape of a blood vessel, when expanded inside the blood vessel, such that the outer wall can expand in multiple locations to conform to multiple bulges of the blood vessel and can contract in multiple locations to conform to multiple narrowed regions of the blood vessel.
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公开(公告)号:US11273062B2
公开(公告)日:2022-03-15
申请号:US16378417
申请日:2019-04-08
发明人: Eran Goldberg , Noa Axelrod , Yair A. Neumann , Boaz Manash , David Maimon , Eyal Leiba , Ralph Schneider , Liron Tayeb
IPC分类号: A61F2/966 , A61M25/00 , B29D23/00 , A61F2/24 , A61F2/95 , A61F2/958 , B29K105/08 , A61M29/00 , A61F2/962
摘要: An expandable sheath is disclosed herein, which has a first polymeric layer and a braided layer positioned radially outward of the first polymeric layer. The braided layer includes a plurality of filaments braided together. The expandable sheaths further include a resilient elastic layer positioned radially outward of the braided layer. The elastic layer is configured to apply radial force to the braided layer and the first polymeric layer. The expandable sheath further includes a second polymeric layer positioned radially outward of the elastic layer and bonded to the first polymeric layer such that the braided layer and the elastic layer are encapsulated between the first and second polymeric layers. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.
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公开(公告)号:US11013595B2
公开(公告)日:2021-05-25
申请号:US16100601
申请日:2018-08-10
发明人: Tamir S. Levi , Giolnara Pinhas , Liraz Marom , Elena Sherman , Noam Mizrahi , Delfin Rafael Ruiz , Sandip Vasant Pawar , Liron Tayeb
摘要: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame having an inflow end, an outflow end, and a longitudinal axis. A leaflet structure is positioned within the frame and secured thereto, and a sealing element is secured to the frame. The sealing element includes a first woven portion extending circumferentially around the frame. The first woven portion includes a plurality of interwoven filaments. The sealing element further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. At least a portion of the filaments exit the weave of the first woven portion and form loops extending radially outwardly from the frame.
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公开(公告)号:US20170128199A1
公开(公告)日:2017-05-11
申请号:US15345857
申请日:2016-11-08
发明人: Nikolay Gurovich , Mohammad Jafari , Liron Tayeb , Ilan Tamir , Ziv Yohanan , Noam Nir , David Maimon , Boaz Manash
IPC分类号: A61F2/24
CPC分类号: A61F2/2409 , A61F2/2418
摘要: Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A prosthetic valve may comprise a radially compressible main body and a one-way valve portion. The prosthetic valve may further comprise one or more ventricular anchors coupled to the main body and disposed outside of the main body. The ventricular anchors may be configured such that a reduced profile of the prosthetic valve is possible. A space may be provided between an outer surface of the main body and the ventricular anchors for receiving native mitral valve leaflets. The prosthetic valve may include an atrial sealing member adapted for placement above the annulus of the mitral valve. Methods and devices for receiving the native mitral valve leaflets between the ventricular anchors and the main body are described.
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公开(公告)号:US20240335310A1
公开(公告)日:2024-10-10
申请号:US18747761
申请日:2024-06-19
发明人: Eran Goldberg , Noa Axelrod Manela , Yair A. Neumann , Boaz Manash , David Maimon , Eyal Leiba , Ralph Schneider , Liron Tayeb
IPC分类号: A61F2/966 , A61F2/24 , A61F2/95 , A61F2/958 , A61F2/962 , A61M25/00 , A61M29/00 , B29D23/00 , B29K105/08
CPC分类号: A61F2/966 , A61F2/2436 , A61F2/9526 , A61M25/0012 , A61M25/0023 , B29D23/00 , A61F2/9517 , A61F2/9522 , A61F2002/9583 , A61F2002/9623 , A61F2002/9665 , A61F2250/001 , A61M2025/0024 , A61M25/0045 , A61M25/005 , A61M25/0074 , A61M29/00 , A61M2205/0216 , B29K2105/0827
摘要: An expandable sheath is disclosed herein, which has a first polymeric layer and a braided layer positioned radially outward of the first polymeric layer. The braided layer includes a plurality of filaments braided together. The expandable sheaths further include a resilient elastic layer positioned radially outward of the braided layer. The elastic layer is configured to apply radial force to the braided layer and the first polymeric layer. The expandable sheath further includes a second polymeric layer positioned radially outward of the elastic layer and bonded to the first polymeric layer such that the braided layer and the elastic layer are encapsulated between the first and second polymeric layers. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.
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公开(公告)号:US12048623B2
公开(公告)日:2024-07-30
申请号:US17492408
申请日:2021-10-01
发明人: Nikolay Gurovich , Michael Bukin , Alexey Tsypenyuk , Elena Sherman , Dikla Kersh , Boaz Manash , Liron Tayeb , Ziv Yohanan , Alexander Barash , Yair A. Neumann , Tomer Saar
IPC分类号: A61F2/24
CPC分类号: A61F2/2418 , A61F2220/0033 , A61F2220/0075 , A61F2220/0091 , A61F2230/0069
摘要: A prosthetic valve has an annular frame including a plurality of strut members that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration. A leaflet structure is situated at least partially within the frame. The leaflet structure includes a plurality of leaflets, each leaflet having opposing commissure tab portions on opposite sides of the leaflet. Each commissure tab portion is paired with an adjacent commissure tab portion of an adjacent leaflet to form a commissure. The commissure tab portions of each leaflet are folded to form a plurality of layers positioned on the inside of the frame. A reinforcement member is positioned between the layers of each commissure tab portion.
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公开(公告)号:US11883288B2
公开(公告)日:2024-01-30
申请号:US17113268
申请日:2020-12-07
发明人: David Maimon , Eran Goldberg , Liron Tayeb
CPC分类号: A61F2/2436 , A61M25/0023 , A61M25/0662 , A61M25/005 , A61M25/0045 , A61M2025/0024 , A61M2205/0216 , A61M2205/0266
摘要: The expandable sheath and methods of use disclosed herein are used to deliver a prosthetic device through a patient's vasculature. The sheath is constructed to be expandable in the circumferential direction, while maintaining sufficient stiffness in the longitudinal direction to withstand pushing and resist kinking. The sheath includes a plurality of curved arms extending outwardly from a longitudinally extending spine. The curved arms move away from the longitudinal axis of the sheath when pushed radially outwardly by a passing prosthetic device, and move back toward the longitudinal axis once the prosthetic device has passed.
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