公开(公告)号：US20250057651A1

公开(公告)日：2025-02-20

申请号：US18938921

申请日：2024-11-06

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Eran Grosu ,  Michael Bukin ,  Nikolai Gurovich ,  Anatoly Dvorsky

IPC: A61F2/24

Abstract: This disclosure is directed to prosthetic heart valves and actuation assemblies for prosthetic heart valves having actuators extending through actuation brackets secured to a prosthetic heart valve frame. In some examples, each actuator extends through and is pivotable relative to two actuation brackets secured to the inner surface of the prosthetic heart valve frame. In other examples, each actuator extends through and is pivotable relative to a vertically extending post of the frame. In this way, the actuators may move angularly relative to the longitudinal axis of the frame during the radial expansion and compression of the prosthetic heart valve. This may prevent bending and buckling of the actuators during the deployment of the prosthetic heart valve.

公开(公告)号：US20240350262A1

公开(公告)日：2024-10-24

申请号：US18761769

申请日：2024-07-02

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Noam Miller ,  Anatoly Dvorsky ,  Eran Grosu ,  Michael Bukin ,  Nikolai Gurovich

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/243

Abstract: A prosthetic valve includes a frame having a first frame portion and a first window formed in the first frame portion. A threaded rod is coupled to the first frame portion and extends through the first window. Rotation of the threaded rod relative to the first frame portion radially expands or radially compresses the frame. A stopper is disposed within the first window and coupled to the threaded rod. The stopper is fixed in axial position relative to the threaded rod and axially movable within the first window by rotation of the threaded rod. The stopper can engage a first edge of the window to produce radial compression of the frame.

公开(公告)号：US20240350261A1

公开(公告)日：2024-10-24

申请号：US18761651

申请日：2024-07-02

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Alon Ben-Yosef ,  Eran Grosu ,  Michael Bukin ,  Nikolai Gurovich ,  Anatoly Dvorsky ,  Noam Miller ,  Ilan Leshecz ,  Joseph Mordechai Leichner

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2220/0033 ,  A61F2230/0006 ,  A61F2250/001

Abstract: This disclosure is directed to prosthetic heart valves having frames with features configured to increase the flexibility of certain frame components and/or to allow the frame to maintain an at least substantially cylindrical shape during deployment. In one example, a frame for an implantable device can include a first end, a second end, a plurality of angled struts, and a plurality of vertical struts. One or more vertical struts of the plurality of vertical struts includes a fixed end portion connected to a vertical strut junction, a free end portion, and a plurality of apertures disposed between the fixed end portion and the free end portion and configured to increase the flexibility of the one or more vertical struts. In some examples, one or more vertical struts of the plurality of vertical struts comprises an axially compressible aperture configured to enable the axial compression of the strut.

公开(公告)号：US20240325145A1

公开(公告)日：2024-10-03

申请号：US18739032

申请日：2024-06-10

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Anatoly Dvorsky ,  Eran Grosu ,  Michael Bukin ,  Nikolai Gurovich

IPC: A61F2/24

CPC classification number: A61F2/2433 ,  A61F2/2418 ,  A61F2250/001 ,  A61F2250/0098

Abstract: Certain examples of the disclosure concern a prosthetic device. The prosthetic device can include a radially compressible and expandable frame and a screw actuator coupled to the frame and configured to be rotated to radially expand the frame from a radially compressed state to a radially expanded state. The frame can include two or more pairs of first markers and second markers. The pairs of first and second markers can be circumferentially spaced apart from each other. The first and second markers of each pair can be axially aligned and axially movable relative to one another as the frame radially expands. Positions of the first and second markers can be configured so that a difference in axial distances between respective pairs of the first markers and second markers can indicate a degree of evenness of the frame's radial expansion.

公开(公告)号：US20240099835A1

公开(公告)日：2024-03-28

申请号：US18530682

申请日：2023-12-06

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Tamir S. Levi ,  Anatoly Dvorsky

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2210/0057 ,  A61F2220/0075 ,  A61F2230/0076

Abstract: A prosthetic valve, constituted of: a frame movable between a radially compressed and a radially expanded state; and a plurality of leaflets secured to the frame.

公开(公告)号：US20220401215A1

公开(公告)日：2022-12-22

申请号：US17894051

申请日：2022-08-23

Applicant: Edwards Lifesciences Corporation

Inventor： Anatoly Dvorsky ,  Tamir S. Levi ,  Yair A. Neumann ,  Noa Axelrod Manela ,  Eitan Atias ,  Oren Cohen ,  Elazar Levi Schwarcz ,  Ofir Witzman ,  Noam Miller ,  Boaz Manash ,  Danny M. Garmahi

IPC: A61F2/24 ,  A61F2/95

Abstract: An implantable prosthetic device can include a frame that is radially expandable and compressible between a radially compressed configuration and a radially expanded configuration. The frame can have a first set of a plurality of struts extending in a first direction, and a second set of a plurality of struts extending in a second direction, and each strut of the first set of struts can be pivotably connected to at least one strut of the second set of struts. Each strut can be curved helically with respect to a first, longitudinal axis of the frame, and each strut can be curved with respect to a second axis that is perpendicular to the first, longitudinal axis of the frame.

公开(公告)号：US20220280298A1

公开(公告)日：2022-09-08

申请号：US17826751

申请日：2022-05-27

Applicant: Edwards Lifesciences Corporation

Inventor： Elazar Levi Schwarcz ,  Oren Cohen ,  Anatoly Dvorsky ,  Natanel Simcha Sirote

IPC: A61F2/24

Abstract: A delivery assembly constituted of: a prosthetic valve comprising a plurality of intersecting struts, and a delivery apparatus comprising: a handle; a delivery shaft extending distally from the handle; and a flex sensing assembly, comprising: at least one flex sensor coupled to at least one of the plurality of struts; and a control unit in communication with the at least one flex sensor, wherein the prosthetic valve is movable between a radially compressed configuration and a radially expanded configuration, and wherein, responsive to an output of the at least one flex sensor, the control unit is configured to generate a signal indicative of a diameter of the prosthetic valve.

公开(公告)号：US20200297482A1

公开(公告)日：2020-09-24

申请号：US16813637

申请日：2020-03-09

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Boaz Manash ,  Eyal Leiba ,  Ziv Yohanan ,  Yair A. Neumann ,  Anatoly Dvorsky ,  Jonathan Bar-Or ,  Oren Cohen ,  Ofir Witzman ,  Liron Tayeb ,  Elazar Levi Schwarcz ,  Noam Miller ,  Tomer Saar

IPC: A61F2/24

Abstract: An assembly can comprise a radially expandable and compressible annular frame, at least one linear actuator assembly coupled to the frame and at least one locking mechanism coupled to the frame. The linear actuator can be configured to apply a distally directed force and/or a proximally directed force to the frame to radially expand or compress the frame. The locking mechanism can comprise a first sleeve member connected to the frame at a first location, a second sleeve member having internal threads and being connected to the frame at a second location, and a first screw configured to engage the internal threads of the second sleeve member to retain the frame in a radially expanded state.

公开(公告)号：US20250090311A1

公开(公告)日：2025-03-20

申请号：US18950681

申请日：2024-11-18

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Nikolai Gurovich ,  Gil Senesh ,  Michael Bukin ,  Anatoly Dvorsky ,  Tamir S. Levi ,  Elena Sherman

IPC: A61F2/24 ,  A61F2/00 ,  A61L27/18

Abstract: Outer skirts for a prosthetic heart valve are disclosed. As one example, a prosthetic heart valve can include an annular frame and an outer skirt disposed around an outer surface of the frame. The outer skirt can include a first portion comprising a polymeric material and a second portion comprising a fabric, where the polymeric material has a greater thromboresistance than the fabric. The second portion is secured to an inflow end of the frame and extends toward an intermediate portion of the frame and the first portion extends from the second portion and toward an outflow end of the frame

公开(公告)号：US20240423790A1

公开(公告)日：2024-12-26

申请号：US18825316

申请日：2024-09-05

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Anatoly Dvorsky ,  Michael Bukin ,  Nikolai Gurovich ,  Eran Grosu

IPC: A61F2/24

Abstract: This disclosure is directed to prosthetic heart valves and actuators for prosthetic heart valves. In some examples, the actuator can comprise an internally threaded bore that engages an externally threaded portion of the frame component, such as a stationary post. In some examples, the actuator can comprise an externally threaded end portion that engages an internally threaded bore in a frame component, such as a stationary post.