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    Sealed connectors for portable electronic devices
    21.
    发明授权
    Sealed connectors for portable electronic devices 有权
    用于便携式电子设备的密封连接器

    公开(公告)号：US08246383B2

    公开(公告)日：2012-08-21

    申请号：US12728171

    申请日：2010-03-19

    Applicant: Mathias Schmidt ,  Eric Jol

    Inventor： Mathias Schmidt ,  Eric Jol

    IPC: H01R13/648

    CPC classification number: H01R13/6273 ,  H01R12/7047 ,  H01R12/722 ,  H01R13/405 ,  H01R13/5202 ,  H01R13/5216 ,  H01R13/5219 ,  H01R13/629 ,  H01R13/6582 ,  H01R13/6594 ,  H01R43/16 ,  H01R43/24 ,  Y10T29/49146 ,  Y10T29/49176 ,  Y10T29/4921 ,  Y10T29/4922

    Abstract: A portable electronic device may have a sealed connector secured within a device housing. The sealed connector may have a metal shell. A plastic contact housing may be insert molded within the shell. Conductive signal contacts may be laterally spaced in the contact housing. An elastomeric gasket may be assembled or compression molded onto the metal shell. Left and right metal brackets may be welded onto the metal shell to moisture-seal latch windows. A water-resistant sealing layer may be attached to the bottom plate of the metal shell to moisture-seal alignment rail windows. The sealed connector may be pressed against the device housing to place the gasket in a compressed state. The connector may be secured to the device housing by screwing down the metal brackets to a circuit board assembled within the housing while the gasket is in the compressed state.

    Abstract translation: 便携式电子设备可以具有固定在设备壳体内的密封连接器。 密封连接器可以具有金属外壳。 塑料接触外壳可以在外壳中嵌入成型。 导电信号触点可以在接触壳体中横向间隔开。 可以将弹性体垫圈组装或压塑在金属壳上。 左和右金属支架可以焊接到金属外壳上以防潮锁住窗口。 防水密封层可以附着在金属外壳的底板上以对准导轨窗口。 密封的连接器可以被压靠在装置壳体上以将垫圈置于压缩状态。 当垫圈处于压缩状态时，连接器可以通过将金属支架拧到组装在壳体内的电路板而固定到装置外壳。

    TETRAHYDROPYRIDOTHIOPHENES FOR THE TREATMENT OF PROLIFERATIVE DISEASES SUCH AS CANCER
    22.
    发明申请
    TETRAHYDROPYRIDOTHIOPHENES FOR THE TREATMENT OF PROLIFERATIVE DISEASES SUCH AS CANCER 审中-公开
    用于治疗增殖性疾病（如癌症）的四氢呋喃半胱氨酸

    公开(公告)号：US20100324038A1

    公开(公告)日：2010-12-23

    申请号：US12510362

    申请日：2009-07-28

    Applicant: Klaus Pekari ,  Mathias Schmidt ,  Thomas Bär ,  Thomas Beckers ,  Björn Bartels

    Inventor： Klaus Pekari ,  Mathias Schmidt ,  Thomas Bär ,  Thomas Beckers ,  Björn Bartels

    IPC: A61K31/5377 ,  C07D495/04 ,  A61K31/4365 ,  A61K31/506 ,  A61P35/00 ,  A61P35/02

    CPC classification number: C07D495/04

    Abstract: The invention relates to compounds of formula I, wherein Ra is —C(O)OR1, in which R1 is 1-7C-alkyl, 3-7C-cycloalkyl, or 1-7C-alkyl substituted by one to four substituents independently selected from R2, Rb is -T-Q, in which T is 1-6C-alkylene or 3-7C-cycloalkylene, and either Q is optionally substituted by Rba and/or Rbb and/or Rbc, and is phenyl or naphthyl, or Q is optionally substituted by Rca and/or Rcb, and is Har, or Q is optionally substituted by Rda and/or Rdb, and is Het, or Q is optionally substituted by Rea and/or Reb, and is 3-7C-cycloalkyl, which are useful for the therapy of hyperproliferative diseases, in particular human cancer.

    Abstract translation: 本发明涉及式I化合物，其中R a为-C（O）OR 1，其中R 1为1-7C-烷基，3-7C-环烷基或被一至四个独立地选自 R2，Rb是-TQ，其中T是1-6C-亚烷基或3-7C-亚环烷基，并且Q任选地被Rba和/或Rbb和/或Rbc取代，并且是苯基或萘基，或Q是任选的 被Rca和/或Rcb取代，并且是Har，或Q任选被R da和/或R db取代，并且是Het，或Q任选地被Rea和/或Reb取代，并且是3-7C-环烷基，它们是 可用于治疗过度增殖性疾病，特别是人类癌症。

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