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44 条记录 (耗时 0.03 秒)

    CROSSLINK AGENTS
    21.
    发明申请
    CROSSLINK AGENTS 有权
    CROSSLINK代理

    公开(公告)号：US20110105779A1

    公开(公告)日：2011-05-05

    申请号：US13004228

    申请日：2011-01-11

    申请人： Ivan M. Nunez ,  Joseph A. McGee ,  David E. Seelye

    发明人： Ivan M. Nunez ,  Joseph A. McGee ,  David E. Seelye

    IPC分类号： C07F7/10 ,  C07F7/08

    CPC分类号： C08F226/10 ,  C08F216/125 ,  C08F222/1006 ,  C08F230/08

    摘要： Novel crosslink agents are described that provide for the copolymerization of at least one hydrophilic monomer with at least one lens monomer typically used to prepare materials for ophthalmic lenses. The new crosslink agents have a relatively high selectivity for the hydrophilic monomer and limited reactivity with the crosslink agent used to polymerize the lens monomer.

    摘要翻译： 描述了提供至少一种亲水性单体与通常用于制备眼科镜片材料的至少一种透镜单体共聚的新型交联剂。 新的交联剂对亲水性单体具有较高的选择性，并且与用于聚合透镜单体的交联剂的反应性受限。

    Biomedical devices
    22.
    发明申请
    Biomedical devices 有权
    生物医学装置

    公开(公告)号：US20100317817A1

    公开(公告)日：2010-12-16

    申请号：US12456421

    申请日：2009-06-16

    申请人： Jeffrey G. Linhardt ,  Joseph A. McGee ,  Ivan M. Nunez

    发明人： Jeffrey G. Linhardt ,  Joseph A. McGee ,  Ivan M. Nunez

    IPC分类号： C08G77/00 ,  C08G75/00

    CPC分类号： A61L27/26 ,  A61L27/52 ,  G02B1/043 ,  C08L81/00 ,  C08L83/10 ,  C08L33/04 ,  C08L71/02

    摘要： Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a random copolymer comprising hydrophilic units and hydrophobic units, wherein the random copolymer has at least one thio carbonyl thio fragment of a reversible addition fragmentation chain transfer (“RAFT”) agent are disclosed.

    摘要翻译： 生物医学装置如由混合物的聚合产物形成的隐形眼镜，所述混合物包含（a）包含亲水单元的无规共聚物和疏水单元，其中所述无规共聚物具有至少一个可逆加成断裂链转移的硫代羰基硫代片段（“RAFT “）代理。

    POLYSILOXANES AND POLYSILOXANE PREPOLYMERS WITH VINYL OR EPOXY FUNCTIONALITY
    23.
    发明申请
    POLYSILOXANES AND POLYSILOXANE PREPOLYMERS WITH VINYL OR EPOXY FUNCTIONALITY 有权
    具有乙烯基或环氧官能团的多异氰酸酯和聚硅氧烷预聚物

    公开(公告)号：US20090227804A1

    公开(公告)日：2009-09-10

    申请号：US12042378

    申请日：2008-03-05

    申请人： Yu-Chin Lai ,  Edmond T. Quinn ,  Weihong Lang ,  Ivan M. Nunez

    发明人： Yu-Chin Lai ,  Edmond T. Quinn ,  Weihong Lang ,  Ivan M. Nunez

    IPC分类号： C07D303/02

    CPC分类号： C08G77/16 ,  C08G18/10 ,  C08G18/61 ,  C08G18/672 ,  C08G77/14 ,  C08G77/20 ,  C08G77/458

    摘要： Polysiloxanes having vinyl or epoxy functionality. The polysiloxanes are used to form polymer-based materials having properties particularly suited for biomedical device applications. The polysiloxanes are of general formula I: wherein R is a C2-10 alkenyl, a C2-10 alkyl with an epoxy group or a C5-C7cycloalkyl with an epoxy group; R2, R3 and R4 are each independently selected from the group consisting of hydrogen, C1-4 alkyl, C1-4 fluoroalkyl, optionally substituted phenyl and optionally substituted benzyl; A is —OH or —NHR5, wherein R5 is hydrogen or a C1-3 alkyl; and B is —R1-A or —R6, wherein R1 is a linking group having an alkylene group with 2 to 8 carbon atoms wherein the alkylene group optionally includes ether, urethane or ureido linkages; and R6 is selected from the group consisting of C1-4 alkyl, optionally substituted phenyl or optionally substituted benzyl; and m and n are integers with an m:n ratio from 30:1 to 3:1.

    摘要翻译： 具有乙烯基或环氧官能团的聚硅氧烷。 聚硅氧烷用于形成具有特别适用于生物医学装置应用的特性的聚合物基材料。 聚硅氧烷具有通式I：其中R是C2-10烯基，具有环氧基的C2-10烷基或具有环氧基的C5-C7环烷基; R 2，R 3和R 4各自独立地选自氢，C 1-4烷基，C 1-4氟烷基，任选取代的苯基和任选取代的苄基; A是-OH或-NHR 5，其中R 5是氢或C 1-3烷基; 并且B是-R1-A或-R6，其中R1是具有2至8个碳原子的亚烷基的连接基团，其中亚烷基任选地包括醚，氨基甲酸酯或脲基键; 并且R 6选自C 1-4烷基，任选取代的苯基或任选取代的苄基; m和n为30：1〜3：1的m：n比的整数。

    Polysiloxanes and polysiloxane prepolymers with vinyl or epoxy functionality
    28.
    发明授权
    Polysiloxanes and polysiloxane prepolymers with vinyl or epoxy functionality 有权
    具有乙烯基或环氧官能团的聚硅氧烷和聚硅氧烷预聚物

    公开(公告)号：US07781554B2

    公开(公告)日：2010-08-24

    申请号：US12042378

    申请日：2008-03-05

    申请人： Yu-Chin Lai ,  Edmond T. Quinn ,  Weihong Lang ,  Ivan M. Nunez

    发明人： Yu-Chin Lai ,  Edmond T. Quinn ,  Weihong Lang ,  Ivan M. Nunez

    IPC分类号： C08G77/00

    CPC分类号： C08G77/16 ,  C08G18/10 ,  C08G18/61 ,  C08G18/672 ,  C08G77/14 ,  C08G77/20 ,  C08G77/458

    摘要： Polysiloxanes having vinyl or epoxy functionality. The polysiloxanes are used to form polymer-based materials having properties particularly suited for biomedical device applications. The polysiloxanes are of general formula I: wherein R is a C2-10 alkenyl, a C2-10 alkyl with an epoxy group or a C5-C7cycloalkyl with an epoxy group; R2, R3 and R4 are each independently selected from the group consisting of hydrogen, C1-4 alkyl, C1-4 fluoroalkyl, optionally substituted phenyl and optionally substituted benzyl; A is —OH or —NHR5, wherein R5 is hydrogen or a C1-3 alkyl; and B is —R1-A or —R6, wherein R1 is a linking group having an alkylene group with 2 to 8 carbon atoms wherein the alkylene group optionally includes ether, urethane or ureido linkages; and R6 is selected from the group consisting of C1-4 alkyl, optionally substituted phenyl or optionally substituted benzyl; and m and n are integers with an m:n ratio from 30:1 to 3:1.

    摘要翻译： 具有乙烯基或环氧官能团的聚硅氧烷。 聚硅氧烷用于形成具有特别适用于生物医学装置应用的特性的聚合物基材料。 聚硅氧烷具有通式I：其中R是C2-10烯基，具有环氧基的C2-10烷基或具有环氧基的C5-C7环烷基; R 2，R 3和R 4各自独立地选自氢，C 1-4烷基，C 1-4氟烷基，任选取代的苯基和任选取代的苄基; A是-OH或-NHR 5，其中R 5是氢或C 1-3烷基; 并且B是-R1-A或-R6，其中R1是具有2至8个碳原子的亚烷基的连接基团，其中亚烷基任选地包括醚，氨基甲酸酯或脲基键; 并且R 6选自C 1-4烷基，任选取代的苯基或任选取代的苄基; m和n为30：1〜3：1的m：n比的整数。

    Crosslink Agents and Dual Radical Cure Polymer
    29.
    发明申请
    Crosslink Agents and Dual Radical Cure Polymer 有权
    交联剂和双自由基固化聚合物

    公开(公告)号：US20090023876A1

    公开(公告)日：2009-01-22

    申请号：US12168944

    申请日：2008-07-08

    申请人： Ivan M. Nunez ,  Joseph A. McGee ,  David E. Seelye

    发明人： Ivan M. Nunez ,  Joseph A. McGee ,  David E. Seelye

    IPC分类号： C08F26/10 ,  C07C69/602 ,  C08F220/28 ,  C07C211/36 ,  C08F12/28

    CPC分类号： C08F226/10 ,  C08F216/125 ,  C08F220/18 ,  C08F230/08

    摘要： Crosslink agents used to copolymerize at least one hydrophilic monomer with at least one lens monomer typically used to prepare polymeric materials for ophthalmic lenses. The crosslink agents have a relatively high selectivity for the hydrophilic monomer and limited reactivity with the crosslink agent used to polymerize the lens monomer. Accordingly, the invention is also directed to a hydrophilic crosslinked polymer that comprises at least two monomeric units and at least two different crosslink units. The use of the dual crosslink system provides an improved means to control the final chemical, physical and structural characteristics of the resulting polymer.

    摘要翻译： 用于将至少一种亲水性单体与至少一种通常用于制备用于眼科镜片的聚合物材料的透镜单体共聚的交联剂。 交联剂对亲水性单体具有较高的选择性，并且与用于聚合透镜单体的交联剂的反应性受限。 因此，本发明还涉及包含至少两个单体单元和至少两个不同交联单元的亲水性交联聚合物。 双重交联体系的使用提供了一种改进的方法来控制所得聚合物的最终化学，物理和结构特征。