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公开(公告)号：US09943842B2
公开(公告)日：2018-04-17
申请号：US15793790
申请日：2017-10-25
申请人： Hamilton Company
CPC分类号： B01L3/0279 , B01L3/0275 , B01L3/563 , B01L2200/023 , B01L2200/025 , B01L2200/026 , B01L2200/04 , B01L2200/0689 , B01L2300/0832 , B01L2300/123
摘要： Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.
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公开(公告)号：US20180099284A1
公开(公告)日：2018-04-12
申请号：US15838759
申请日：2017-12-12
申请人： Hamilton Company
CPC分类号： B01L3/0279 , B01L3/0275 , B01L3/563 , B01L2200/023 , B01L2200/025 , B01L2200/026 , B01L2200/04 , B01L2200/0689 , B01L2300/0832 , B01L2300/123
摘要： Pipette assembly comprising a pipette device, a pipette tip, and an expanding mandrel collet coupling device coupling the tip to the pipette device, the coupling device comprising: circumferentially spaced apart segments, an annular base disposed below the segments and comprising a distal portion, an elastomeric element circumscribing the distal portion, and upwardly extending circumferentially spaced apart arms attached at first ends to the annular base and having upper free ends each supporting a different one of the segments configured to expand between a first and a second greater circumference for engaging a first interior working surface of the tip in concurrence with the elastomeric element sealing against a second interior working surface below the first surface and in concurrence with an abutment between a disk exteriorly disposed about a medial portion of the arms and a stepped interior shoulder of the tip disposed between the first and second working surfaces.
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公开(公告)号：US11235318B2
公开(公告)日：2022-02-01
申请号：US17369625
申请日：2021-07-07
申请人： Hamilton Company
摘要： Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.
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公开(公告)号：US11020738B2
公开(公告)日：2021-06-01
申请号：US17124143
申请日：2020-12-16
申请人： Hamilton Company
摘要： Pipette assembly that includes a pipette device, a pipette tip, and a leaf spring coupling device coupling the tip to the pipette device, the coupling device includes a plurality of circumferentially disposed elements or segments in the form of flexible leaf springs with stabilizer plateaus used to retain a pipette tip to the coupler and prevent the pipette tip from rocking on the coupler and a distal elastomeric element, such as an O-ring, and the pipette tip includes dual complemental working surfaces in the pipette tip to provide precise control of an axial coupled position defined as an axial distance from a distally facing axial stop surface of the pipette tip coupler to the end of the pipette tip that contacts liquid when the pipette tip coupler and disposable pipette tip are in a coupled configuration.
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公开(公告)号：US20210023550A1
公开(公告)日：2021-01-28
申请号：US17070686
申请日：2020-10-14
申请人： Hamilton Company
摘要： Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.
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公开(公告)号：US20200276575A1
公开(公告)日：2020-09-03
申请号：US16842529
申请日：2020-04-07
申请人： Hamilton Company
摘要： Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from, respectively, a pipette tip coupler mounted on a pipette device. The pipette tip couplers include an elastomeric element, a discrete segment assembly, and a coupler stop shoulder surface. The pipette tips include a groove in a first cylindrical section, a second cylindrical section, a tip stop shoulder surface at the interface of the first and second cylindrical sections, a third cylindrical section, a sealing seat surface at the interface of the second and third cylindrical sections, and a fourth section adjacent to the third cylindrical section. When the pipette tip is mounted on the pipette tip coupler, the discrete segment assembly abuts the tip groove, the coupler stop shoulder surface abuts the tip stop shoulder surface, and the elastomeric element abuts the sealing seat surface.
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公开(公告)号：US10730040B2
公开(公告)日：2020-08-04
申请号：US16514567
申请日：2019-07-17
申请人： Hamilton Company
摘要： Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from an expanding mandrel pipette tip coupler mounted on a pipette device. The pipette tip couplers include circumferentially spaced apart segments for engaging an interior surface of a pipette tip, an annular base disposed below the segments, a distal elastomeric element disposed around a distal stem portion for sealing against the interior surface of the pipette tip, upwardly extending circumferentially spaced apart arms each supporting a different segment, and a stop disk for abutting a stop shoulder in a pipette tip. The pipette tips include a groove in a first cylindrical section, a second cylindrical section, a pipette tip stop shoulder surface, a third cylindrical section, and a sealing seat surface.
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公开(公告)号：US20190217287A1
公开(公告)日：2019-07-18
申请号：US16298681
申请日：2019-03-11
申请人： Hamilton Company
摘要： Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from, respectively, a pipette tip coupler mounted on a pipette device. The pipette tip couplers include an elastomeric element, a discrete segment assembly, and a coupler stop shoulder surface. The pipette tips include a groove in a first cylindrical section, a second cylindrical section, a tip stop shoulder surface at the interface of the first and second cylindrical sections, a third cylindrical section, a sealing seat surface at the interface of the second and third cylindrical sections, and a fourth section adjacent to the third cylindrical section. When the pipette tip is mounted on the pipette tip coupler, the discrete segment assembly abuts the tip groove, the coupler stop shoulder surface abuts the tip stop shoulder surface, and the elastomeric element abuts the sealing seat surface.
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公开(公告)号：US20180133716A1
公开(公告)日：2018-05-17
申请号：US15850087
申请日：2017-12-21
申请人： Hamilton Company
CPC分类号： B01L3/0279 , B01L3/02 , B01L3/0275 , B01L3/563 , B01L2200/02 , B01L2200/023 , B01L2200/025 , B01L2200/026 , B01L2200/04 , B01L2200/0689 , B01L2300/0832 , B01L2300/123 , G01N35/10 , G01N35/1011 , G01N2035/1025 , G01N2035/103
摘要： Pipette assembly comprising a pipette device, a pipette tip, and an expanding mandrel collet coupling device coupling the tip to the pipette device, the coupling device comprising: circumferentially spaced apart segments, an annular base disposed below the segments and comprising a distal portion, an elastomeric element circumscribing the distal portion, and upwardly extending circumferentially spaced apart arms attached at first ends to the annular base and having upper free ends each supporting a different one of the segments configured to expand between a first and a second greater circumference for engaging a first interior working surface of the tip in concurrence with the elastomeric element sealing against a second interior working surface below the first surface and in concurrence with an abutment between a disk exteriorly disposed about a medial portion of the arms and a stepped interior shoulder of the tip disposed between the first and second working surfaces.
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公开(公告)号：US09937493B1
公开(公告)日：2018-04-10
申请号：US15838811
申请日：2017-12-12
申请人： Hamilton Company
CPC分类号： B01L3/0279 , B01L3/0275 , B01L3/563 , B01L2200/023 , B01L2200/025 , B01L2200/026 , B01L2200/04 , B01L2200/0689 , B01L2300/0832 , B01L2300/123
摘要： Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a first elastomeric element carried by the coupler at a location superior to the coupler shoulder; and a second elastomeric element carried by the coupler at a location inferior to the coupler shoulder wherein the first elastomeric element has a compressed radially expanded state that provides a sealing abutment with a first working surface formed in the interior surface of the pipette tip while compressing the second elastomeric element into sealing abutment with a second working surface formed in the interior surface of the pipette tip and while abutting the proximally facing axial stop surface of the pipette tip with the distally facing axial stop surface of the pipette coupler to define an axial coupling position of the pipette tip on the pipette device.
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