Pipetting Device, Pipette Tip Coupler, and Pipette Tip: Devices and Methods

    公开(公告)号:US20210331154A1

    公开(公告)日:2021-10-28

    申请号:US17369625

    申请日:2021-07-07

    申请人: Hamilton Company

    IPC分类号: B01L3/02 B01L3/00 G01N35/10

    摘要: Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.

    Pipetting Device, Pipette Tip Coupler, and Pipette Tip: Devices and Methods

    公开(公告)号:US20200254441A1

    公开(公告)日:2020-08-13

    申请号:US16864417

    申请日:2020-05-01

    申请人: Hamilton Company

    IPC分类号: B01L3/02 G01N35/10 B01L3/00

    摘要: Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from a pipette tip coupler mounted on a pipette device. The pipette tip couplers include a shank, a coupler body distal to the shank, a distal stem and distal end plate distal to the coupler body, a proximal elastomeric element disposed around the shank, a distal elastomeric element disposed around the distal stem, and a coupler stop shoulder surface between the proximal elastomeric element and distal elastomeric element. When a pipette tip is mounted on the pipette tip coupler, the proximal elastomeric element abuts the interior surface of the pipette tip for securing the pipette tip to the coupler, and the distal elastomeric element abuts the interior surface of the pipette tip to form a seal between the coupler and the pipette tip.

    Pipetting Device, Pipette Tip Coupler, and Pipette Tip: Devices and Methods

    公开(公告)号:US20180043349A1

    公开(公告)日:2018-02-15

    申请号:US15793364

    申请日:2017-10-25

    申请人: Hamilton Company

    IPC分类号: B01L3/02

    摘要: Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.

    Pipetting device, pipette tip coupler, and pipette tip: devices and methods

    公开(公告)号:US11065614B2

    公开(公告)日:2021-07-20

    申请号:US17070686

    申请日:2020-10-14

    申请人: Hamilton Company

    IPC分类号: B01L3/02 G01N35/10 B01L3/00

    摘要: Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.

    Pipetting device, pipette tip coupler, and pipette tip: devices and methods

    公开(公告)号:US10888858B2

    公开(公告)日:2021-01-12

    申请号:US16864417

    申请日:2020-05-01

    申请人: Hamilton Company

    IPC分类号: B01L3/02 B01L3/00 G01N35/10

    摘要: Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from a pipette tip coupler mounted on a pipette device. The pipette tip couplers include a shank, a coupler body distal to the shank, a distal stem and distal end plate distal to the coupler body, a proximal elastomeric element disposed around the shank, a distal elastomeric element disposed around the distal stem, and a coupler stop shoulder surface between the proximal elastomeric element and distal elastomeric element. When a pipette tip is mounted on the pipette tip coupler, the proximal elastomeric element abuts the interior surface of the pipette tip for securing the pipette tip to the coupler, and the distal elastomeric element abuts the interior surface of the pipette tip to form a seal between the coupler and the pipette tip.

    Pipetting device, pipette tip coupler, and pipette tip: devices and methods

    公开(公告)号:US10766035B1

    公开(公告)日:2020-09-08

    申请号:US16816012

    申请日:2020-03-11

    申请人: Hamilton Company

    摘要: Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from an expanding mandrel collet coupling device. The pipette tip couplers include a central body, a spacer with cogs circumscribing the central body, an expanding mandrel collet circumscribing the spacer having an annular base and circumferentially spaced apart upwardly extending collet arms, and an elastomeric element circumscribing the central body. The cogs protrude through spaces between the collet arms. The collet arms are attached to the annular base and configured to expand between a first and a second circumference for engaging a first interior surface of the tip, with the elastomeric element sealing against a second interior surface below the first surface, and with an abutment between the cogs and a stepped interior shoulder of the pipette tip disposed between the first and second interior surfaces.

    Pipetting Device, Pipette Tip Coupler, and Pipette Tip: Devices and Methods

    公开(公告)号:US20200261916A1

    公开(公告)日:2020-08-20

    申请号:US16816012

    申请日:2020-03-11

    申请人: Hamilton Company

    IPC分类号: B01L9/00 B01L3/02 B01L3/00

    摘要: Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from an expanding mandrel collet coupling device. The pipette tip couplers include a central body, a spacer with cogs circumscribing the central body, an expanding mandrel collet circumscribing the spacer having an annular base and circumferentially spaced apart upwardly extending collet arms, and an elastomeric element circumscribing the central body. The cogs protrude through spaces between the collet arms. The collet arms are attached to the annular base and configured to expand between a first and a second circumference for engaging a first interior surface of the tip, with the elastomeric element sealing against a second interior surface below the first surface, and with an abutment between the cogs and a stepped interior shoulder of the pipette tip disposed between the first and second interior surfaces.