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30 条记录 (耗时 0.049 秒)

    Multilayer drug delivery system with barrier against antagonist exposure
    21.
    发明申请
    Multilayer drug delivery system with barrier against antagonist exposure 审中-公开
    具有阻挡拮抗剂暴露的多层药物递送系统

    公开(公告)号：US20060257460A1

    公开(公告)日：2006-11-16

    申请号：US11432871

    申请日：2006-05-12

    申请人： Rolf Jansen ,  Dina Coronado

    发明人： Rolf Jansen ,  Dina Coronado

    IPC分类号： A61F13/02 ,  A61L15/16

    CPC分类号： A61K9/7061 ,  A61F2013/0296

    摘要： A multilayered drug delivery system with a barrier suitable for delivery of drug through an individual's body surface with antagonist to the drug in the device. By placing a barrier between two adjacent layers to shield the antagonist, unintended antagonist flow due to migration of an antagonist matrix between the adjacent matrix layers in the system to a patient is avoided.

    摘要翻译： 一种多层药物递送系统，其具有适于通过个体身体表面递送药物的屏障，该装置具有拮抗药物的药物。 通过在两个相邻层之间放置屏障以屏蔽拮抗剂，避免了由于系统中的相邻基体层之间的拮抗剂基质迁移至患者而导致的非预期的拮抗剂流动。

    Chromate-free conversion layer and process for producing the same
    24.
    发明授权
    Chromate-free conversion layer and process for producing the same 有权
    不含铬（VI）的转化层及其制备方法

    公开(公告)号：US06287704B1

    公开(公告)日：2001-09-11

    申请号：US09171558

    申请日：1999-03-29

    申请人： Patricia Preikschat ,  Rolf Jansen ,  Peter Hulser

    发明人： Patricia Preikschat ,  Rolf Jansen ,  Peter Hulser

    IPC分类号： B32B1504

    CPC分类号： C23C22/34 ,  C23C22/53 ,  C23C2222/10 ,  Y10T428/12583 ,  Y10T428/1259 ,  Y10T428/12611 ,  Y10T428/12792 ,  Y10T428/12799

    摘要： A chromium(VI)-free, chromium(III)-containing and substantially coherent conversion layer on zinc or zinc alloys presenting, even in the absence of further components such as silicate, cerium, aluminum and borate, a corrosion protection of approx. 100 to 1000 h in the salt spray test according to DIN 50021 SS or ASTM B 117-73 until first attack according to DIN 50961 Chapter 10; being clear, transparent and substantially colorless and presenting multi-colored iridescence; having a layer thickness of approx. 100 nm to 1000 nm; and being hard, adhering well and being resistant to wiping.

    摘要翻译： 即使在不存在其它成分如硅酸盐，铈，铝和硼酸盐的情况下，锌或锌合金上的含铬（VI） - 含铬（III）的基本相干的转化层也具有防腐蚀性。 在根据DIN 50021 SS或ASTM B 117-73的盐雾试验中，100至1000小时，直到根据DIN 50961第10章的第一次攻击; 透明，基本无色，呈现多色虹彩; 层厚约为 100nm至1000nm; 坚硬，贴合良好，耐擦拭。

    Chromium(VI)-free conversion layer and method for producing it
    27.
    发明授权
    Chromium(VI)-free conversion layer and method for producing it 有权
    不含铬（VI）的转化层及其制备方法

    公开(公告)号：US07314671B1

    公开(公告)日：2008-01-01

    申请号：US10894105

    申请日：2004-07-19

    申请人： Patricia Preikschat ,  Rolf Jansen ,  Peter Hulser

    发明人： Patricia Preikschat ,  Rolf Jansen ,  Peter Hulser

    IPC分类号： B32B15/00 ,  B32B15/04

    CPC分类号： C23C28/00 ,  C23C22/34 ,  C23C22/53 ,  C23C28/321 ,  C23C28/322 ,  C23C28/345 ,  C23C28/3455 ,  C23C2222/10 ,  Y10T428/12792

    摘要： A chromium(VI)-free, chromium(III)-containing and substantially coherent conversion layer on zinc or zinc alloys presenting, even in the absence of further components such as silicate, cerium, aluminum and borate, a corrosion protection of approx. 100 to 1000 h in the salt spray test according to DIN 50021 SS or ASTM B 117-73 until first attack according to DIN 50961 Chapter 10; being clear, transparent and substantially colorless and presenting multi-colored iridescence; having a layer thickness of approx. 100 nm to 1000 nm; and being hard, adhering well and being resistant to wiping.

    摘要翻译： 即使在不存在其它成分如硅酸盐，铈，铝和硼酸盐的情况下，锌或锌合金上的含铬（VI） - 含铬（III）的基本相干的转化层也具有防腐蚀性。 在根据DIN 50021 SS或ASTM B 117-73的盐雾试验中，100至1000小时，直到根据DIN 50961第10章的第一次攻击; 透明，基本无色，呈现多色虹彩; 层厚约为 100nm至1000nm; 坚硬，贴合良好，耐擦拭。

    Method for the enantioselective preparation of 3,3-diphenyl-2,3-epoxy propionic acid esters
    29.
    发明授权
    Method for the enantioselective preparation of 3,3-diphenyl-2,3-epoxy propionic acid esters 有权
    3,3-二苯基-2,3-环氧丙酸酯的对映选择性制备方法

    公开(公告)号：US06677465B2

    公开(公告)日：2004-01-13

    申请号：US10181457

    申请日：2002-10-29

    申请人： Rolf Jansen

    发明人： Rolf Jansen

    IPC分类号： C07D30102

    CPC分类号： C07C69/732 ,  C07D303/48

    摘要： The invention relates to a process for the enantioselective preparation of glycide ester (I) by (a) dihydroxylation of a corresponding 3-phenyl cinnamate (II) by osmium (VIII) oxide catalysis in the presence of a Sharpless ligand and an oxidizing agent to form the dihydroxy ester (III), (b) selective conversion of the hydroxy function in position 2 of the dihydroxy ester (III) to a leaving group, (c) intramolecular substitution of the leaving group through the hydroxy function in position 3 to form the glycide ester (I), in which R1 denotes C1-C10 alkyl, aryl, or arylalkyl, which may be substituted, R2 denotes C1-C10 alkyl, aryl, arylalkyl, halogen, C1-C10 alkoxy, acyloxy, or amide, which may be substituted, and n is 0 to 5.

    摘要翻译： 本发明涉及通过（a）通过锇（VIII）氧化物催化在无沙子配体和氧化剂存在下相应的3-苯基肉桂酸酯（II）二羟基化作用来对映选择性制备甘氨酸酯（I）的方法， 形成二羟基酯（III），（b）将二羟基酯（III）的位置2上的羟基官能团选择性转化为离去基团，（c）离去基团通过位置3的羟基官能团分子取代形成 其中R 1表示可被取代的C 1 -C 10烷基，芳基或芳基烷基的缩水甘油酯（I），R 2表示C 1 -C 10烷基，芳基，芳基烷基，卤素，C 1 -C 10烷氧基，酰氧基或酰胺， 被替代，而且是0到5。

    Device for carrying out an electro-chemical treatment
    30.
    发明授权
    Device for carrying out an electro-chemical treatment 失效
    进行电化学处理的方法和装置

    公开(公告)号：US06630060B1

    公开(公告)日：2003-10-07

    申请号：US09614578

    申请日：2000-07-12

    申请人： Markku Väärni ,  Dirk Bube ,  Rolf Jansen ,  Alois Müller

    发明人： Markku Väärni ,  Dirk Bube ,  Rolf Jansen ,  Alois Müller

    IPC分类号： C25D1700

    CPC分类号： C25D5/08 ,  C25D3/22 ,  C25D3/38 ,  C25D3/44 ,  C25D5/003 ,  C25D17/02 ,  C25D17/16 ,  C25D21/04 ,  H01M8/065 ,  H01M8/0656

    摘要： A method of carrying out an electro-chemical treatment, especially for electro-chemically coating conducting parts or parts made to be conducting, in a container which is filled with an electrolyte and in which there are arranged two electrodes which are connected to a constant voltage source, has the parts, while being treated in the electrolyte, being continuously re-arranged in the rotating basket. The parts are cathodically switched by a hub of the basket. The electrolytic solution is pumped in a cycle through the container, with the container remaining sealed so as to be gas-tight.

    摘要翻译： 一种进行电化学处理的方法，特别是用于将导电部件或导电部件电化学涂覆在填充有电解质的容器中，并且其中布置有两个连接到恒定电压的电极 来源，在处理电解液时，具有不断重新排列在旋转篮中的部件。 这些部件由篮子的轮毂阴极切换。 电解液在循环中被泵送通过容器，容器保持密封以便气密。