公开(公告)号：US5436925A

公开(公告)日：1995-07-25

申请号：US205671

申请日：1994-03-01

申请人： Hong Lin ,  Kok-Wai Chang ,  David K. Donald

发明人： Hong Lin ,  Kok-Wai Chang ,  David K. Donald

IPC分类号： G01C19/72 ,  H01S3/06 ,  H01S3/067 ,  H01S3/07 ,  H01S3/083 ,  H01S3/098 ,  H01S3/17 ,  H01S3/08

CPC分类号： H01S3/1118 ,  H01S3/06791

摘要： A CPM mode-locked fiber ring laser including an ion-implanted semiconductor saturable absorber providing sub-picosecond pulses at rapid repetition rates. The laser provides compact, turn-key capability and is polarization insensitive.

摘要翻译： 一种CPM模式锁定光纤环形激光器，其包括以快速重复率提供亚皮秒脉冲的离子注入的半导体可饱和吸收体。 激光器提供紧凑的交钥匙功能，并且是极化不敏感的。

公开(公告)号：US5384316A

公开(公告)日：1995-01-24

申请号：US975544

申请日：1993-02-18

申请人： David K. Donald ,  Mark Furber

发明人： David K. Donald ,  Mark Furber

IPC分类号： A61K31/435 ,  A61P37/06 ,  C07D498/22 ,  C07H19/01 ,  A61K31/42

CPC分类号： C07D498/22 ,  C07H19/01

摘要： Compounds of formula (I) are provided, wherein R.sup.1 represents OH or OCH.sub.3 ; R.sup.2 represents OH or H; R.sup.3 represents methyl, ethyl, propyl or allyl; X represents O, (H,OH) or (H,H); m represents 0 or 1; n represents 1 or 2; and pharmaceutically acceptable derivatives thereof; provided that when n is 1, then R.sup.3 is allyl or propyl. The compounds are indicated inter alia as immunosuppresive agents. ##STR1##

摘要翻译： PCT No.PCT / GB91 / 01384 Sec。 371日期：1993年2月18日 102（e）日期1993年2月18日PCT 1991年8月14日PCT PCT。 第WO92 / 03441号公报 日本3月5日，1992提供式（I）化合物，其中R1表示OH或OCH3; R2表示OH或H; R3表示甲基，乙基，丙基或烯丙基; X表示O，（H，OH）或（H，H）; m表示0或1; n表示1或2; 及其药学上可接受的衍生物; 条件是当n为1时，则R3为烯丙基或丙基。 这些化合物尤其表示为免疫抑制剂。

公开(公告)号：US5365531A

公开(公告)日：1994-11-15

申请号：US980896

申请日：1992-11-24

申请人： Hong Lin ,  Wayne V. Sorin ,  David K. Donald

发明人： Hong Lin ,  Wayne V. Sorin ,  David K. Donald

IPC分类号： G02F1/35 ,  H01S3/06 ,  H01S3/067 ,  H01S3/07 ,  H01S3/083 ,  H01S3/098

CPC分类号： H01S3/1112 ,  H01S3/06791 ,  H01S3/06712

摘要： A figure-8 loop laser having a controllable phase shifter in a Sagnac loop (non-linear amplifying loop mirror). A half-wave plate in series with Faraday optical rotators provide a switchable non-reciprocal 180-degree phase shifter that allows the birefringence of the fiber loop to be adjusted during continuous wave operation. The phase shifter is activated during continuous wave operation to find a minimum threshold and then is turned off, placing the laser in optimum state for mode locking.

摘要翻译： 在Sagnac环路（非线性放大环路镜）中具有可控移相器的图8环形激光器。 与法拉第光学旋转器串联的半波片提供可切换的非互易180度移相器，允许在连续波动操作期间调节光纤回路的双折射。 在连续波操作期间，移相器被激活以找到最小阈值，然后关闭，将激光器置于模式锁定的最佳状态。

公开(公告)号：US4805237A

公开(公告)日：1989-02-14

申请号：US191729

申请日：1988-05-10

申请人： David K. Donald ,  Shih-Yuan Wang ,  Tirumala R. Ranganath ,  Steven A. Newton ,  William R. Trutna ,  David M. Bloom ,  Frank K. David

发明人： David K. Donald ,  Shih-Yuan Wang ,  Tirumala R. Ranganath ,  Steven A. Newton ,  William R. Trutna ,  David M. Bloom ,  Frank K. David

IPC分类号： H04B10/148 ,  H04B9/00

CPC分类号： H04B10/60 ,  H04B10/64

摘要： A parametric photodiode amplifier suitable for detecting light of frequency f and intensity P and having intersecting I:V curves for zero incident light and for incident light of intensity P. These photodiodes typically have an intrinsic density of carriers that is on the order of or less than the density of carriers produced by incident light of intensity P. When the photodiode is biased by an LO signal and is illuminated with modulated light of carrier frequency f, the photodiode output signal contains IF components at the difference between the frequencies of the modulation signal and the frequencies of on the order of the 23 lower harmonics of the LO signal.

摘要翻译： 适用于检测频率f和强度P的光的参数光电二极管放大器，对于零入射光和强度为P的入射光具有相交的I：V曲线。这些光电二极管通常具有等于或小于 比由强度P的入射光产生的载流子的密度。当光电二极管被LO信号偏置并被载波频率f的调制光照射时，光电二极管输出信号包含调制信号的频率之间的差分的IF分量 以及LO信号的23个低次谐波的次数的频率。

公开(公告)号：US06415074B1

公开(公告)日：2002-07-02

申请号：US09727528

申请日：2000-11-28

申请人： David K. Donald ,  Kelvin Chau ,  Kiet D. Ngo ,  Joseph A. Parker

发明人： David K. Donald ,  Kelvin Chau ,  Kiet D. Ngo ,  Joseph A. Parker

IPC分类号： G02B628

CPC分类号： H04J14/0206 ,  H04J14/021 ,  H04J14/0221 ,  H04J14/0227 ,  H04J14/0228 ,  H04J14/0246 ,  H04J14/025 ,  H04J14/0283 ,  H04J14/0293 ,  H04Q11/0066 ,  H04Q2011/0069 ,  H04Q2011/0081 ,  H04Q2011/0083 ,  H04Q2011/0086

摘要： An optical assembly having a light circulating device is used for routing light and may be used with a receiver. The assembly includes a tunable filter for receiving light traveling from the light circulating device and for selecting which wavelengths of light that reach the receiver. A wavelength routing mechanism optically coupled to the tunable filter and located downstream from the circulator is used to prevent undesired dropping of signal wavelengths. The mechanism has a first operational mode preventing light from reaching the receiver and a second operational mode allowing light to reach the receiver. When the filter is tuning, the mechanism is preferably in the first operational mode. Preferably, the assembly has an arrangement of mirror reflections on the first path and the second path so that an even number of mirror reflection are experienced on one path and an odd number on the other path as light is recombined.

摘要翻译： 具有光循环装置的光学组件用于布置光并且可以与接收器一起使用。 组件包括可调滤光器，用于接收从光循环装置传播的光并用于选择到达接收器的哪些波长的光。 光耦合到可调谐滤波器并位于环行器下游的波长路由机制被用于防止信号波长的不期望的丢弃。 该机构具有防止光到达接收器的第一操作模式和允许光到达接收器的第二操作模式。 当过滤器调谐时，机构优选地处于第一操作模式。 优选地，组件在第一路径和第二路径上具有镜面反射的布置，使得当光被重新组合时，在一条路径上经历偶数数量的镜面反射，而在另一条路径上经历奇数。

公开(公告)号：US06398850B1

公开(公告)日：2002-06-04

申请号：US09892203

申请日：2001-06-25

申请人： Leslie A. Field ,  David K. Donald ,  Phillip W. Barth ,  Jonathan Servaites ,  Storrs T. Hoen

发明人： Leslie A. Field ,  David K. Donald ,  Phillip W. Barth ,  Jonathan Servaites ,  Storrs T. Hoen

IPC分类号： B41J219

CPC分类号： B41J2/19

摘要： A thermally-activated gas extraction device that comprises a bubble capture chamber, an exhaust manifold, a tapered extraction chamber and an extraction heater associated with the tapered extraction chamber. The tapered extraction chamber extends from the bubble capture chamber towards the exhaust manifold and has a cross-sectional area that increases towards the exhaust manifold. A gas removal method in which the gas extraction device is provided, a bubble of gas is accumulated in the bubble capture chamber, a portion of the liquid in the tapered extraction chamber heated to nucleate a bubble of vapor, and the bubble of vapor is heated to explosively expand the bubble of vapor into contact with the walls of the tapered extraction chamber and into contact with the bubble of gas to form a composite bubble. Contact with the walls of the tapered extraction moves the composite bubble towards the exhaust manifold. Finally, heating of the composite bubble is discontinued to condense the vapor in the composite bubble.

摘要翻译： 一种热活化气体提取装置，其包括气泡捕获室，排气歧管，锥形抽出室和与锥形抽出室相关联的抽出加热器。 锥形抽出室从气泡捕获室朝向排气歧管延伸并且具有朝向排气歧管增加的横截面面积。 一种气体去除方法，其中提供气体提取装置，气体的气泡积聚在气泡捕获室中，锥形抽出室中的一部分液体被加热以使蒸汽的气泡成核，并且蒸气的气泡被加热 以将爆炸性地膨胀蒸汽气泡与锥形抽出室的壁接触并与气泡接触以形成复合气泡。 与锥形提取物的壁接触将复合气泡朝向排气歧管移动。 最后，中止复合气泡的加热以冷凝复合气泡中的蒸汽。

公开(公告)号：US5960131A

公开(公告)日：1999-09-28

申请号：US18772

申请日：1998-02-04

申请人： Julie E. Fouquet ,  David K. Donald ,  Datong Chen ,  Kok Wai Chang

发明人： Julie E. Fouquet ,  David K. Donald ,  Datong Chen ,  Kok Wai Chang

IPC分类号： H01B11/00 ,  G02B6/28 ,  G02B6/30 ,  G02B6/35 ,  G02B6/36 ,  G02B26/02 ,  G02B26/08 ,  G02B6/26

CPC分类号： G02B6/3538 ,  G02B26/004 ,  G02B6/305 ,  G02B6/3546 ,  G02B6/3568 ,  G02B6/3596 ,  G02B6/3636 ,  G02B6/3652

摘要： A switching element that selectively couples a first optical path to a second optical path through an index-matching fluid includes a tapering region along each of the optical paths to achieve high coupling efficiency at both ends of substrate waveguides that form portions of the two optical paths. The two substrate waveguides are separated by a gap that is filled with the index-matching fluid in order to optically couple the two waveguides. The ends of the waveguides located at the gap have relatively large cross sectional areas to promote high coupling efficiency across the gap. For example, the cross sectional dimensions may be approximately 16 .mu.m.times.8 .mu.m at the interior ends of the two substrate waveguides. On the other hand, the exterior ends have significantly smaller cross sectional areas in order to promote high coupling efficiency to optical fibers. For example, the cross sectional dimensions of an external end may be 8 .mu.m.times.8 .mu.m. The substrate waveguides are adiabatically tapered in order to inhibit reflection. In another embodiment, the tapering regions of the two optical paths are formed along the optical fibers, rather than along the substrate waveguides.

摘要翻译： 通过折射率匹配流体选择性地将第一光路耦合到第二光路的开关元件包括沿着每个光路的逐渐变细的区域，以在形成两个光路的部分的衬底波导的两端处实现高的耦合效率 。 两个衬底波导被填充有折射率匹配流体的间隙分开，以便光耦合两个波导。 位于间隙处的波导的端部具有相对较大的横截面积，以促进间隙上的高耦合效率。 例如，在两个基板波导的内端处的横截面尺寸可以为大约16μm×50μm。 另一方面，为了促进光纤的高耦合效率，外端具有明显较小的横截面积。 例如，外端的横截面尺寸可以是8m×8μm。 衬底波导是绝热的锥形以抑制反射。 在另一个实施例中，沿着光纤而不是沿着衬底波导形成两个光路的渐缩区域。

公开(公告)号：US5852689A

公开(公告)日：1998-12-22

申请号：US842927

申请日：1997-04-09

申请人： David K. Donald

发明人： David K. Donald

IPC分类号： G02B26/08 ,  G02B6/35 ,  G02B26/02

CPC分类号： G02B26/004 ,  G02B6/3538 ,  G02B6/3546 ,  G02B6/3576

摘要： The method builds upon the highly repeatable properties of commercial optical fiber, and using commercial fiber for the waveguides in a fabric of optical switches. The method describes assembly of the fabric, locating the intersections, and a structure for placing the mating resistor.

摘要翻译： 该方法基于商业光纤的高度可重复的性质，并且使用商业光纤用于光开关结构中的波导。 该方法描述了织物的组装，定位交叉点以及用于放置配合电阻器的结构。

公开(公告)号：US5828799A

公开(公告)日：1998-10-27

申请号：US954431

申请日：1997-10-20

申请人： David K. Donald

发明人： David K. Donald

IPC分类号： G02B6/35 ,  G02B26/02

CPC分类号： G02B26/004 ,  G02B6/3538 ,  G02B6/3512 ,  G02B6/3546 ,  G02B6/3576

摘要： A thermal optical switching cell has a channel of either gas or boilable liquid that crosses an optical waveguide at a forty-five degree angle. Two or more appropriately placed heaters use the water/steam/dry states of thermal ink jet technology to quickly insert, or extract, boilable liquid respectively into, or from, the channel. The boilable liquid has an index of refraction close to that of the guide. In the wet state, the channel contains the liquid and nearly all the light of the incoming guide traverses the liquid along the axis of the guide. In the dry state, the channel contains gas. Total internal reflection (TIR) occurs and light is directed at right angles away from the axis of the incoming channel. Adding a second waveguide, perpendicular to, and intersecting the first waveguide at the channel, forms a cross-bar switch. These liquid switching cells toggle between the wet and dry states. No power is required to hold the switch in the most recent state. A monitoring signal is described that can be used to determine the state of the switch. The dry state of these cells is totally internally reflecting. The wet state, however, is transmissive with a small, but objectionable, amount of reflection. A push-pull optical circuit is formed using paired cells and at least one TIR mirror. One of the cells of the circuit is always in the TIR state to provide good isolation. This circuit has the property of reporting the state of the switch-pair so that a fault can be detected. If a fault is detected, repeated activation pulses can be applied to force liquid into the correct places to maintain proper operation of the circuit.

公开(公告)号：US5376663A

公开(公告)日：1994-12-27

申请号：US391538

申请日：1989-07-25

申请人： Martin E. Cooper ,  David K. Donald ,  David N. Hardern

发明人： Martin E. Cooper ,  David K. Donald ,  David N. Hardern

IPC分类号： C07D498/18 ,  C07D498/22 ,  C07H19/01 ,  A61K31/395 ,  A61K31/445 ,  C07D498/16

CPC分类号： C07D498/18 ,  C07D498/22 ,  C07H19/01

摘要： Compounds of formula (I), in which [R.sup.1 and R.sup.2 ], [R.sup.3 and R.sup.4 ] and [R.sup.5 and R.sup.6 ] represent a carbon-carbon bond or two hydrogen atoms; R.sup.2 additionally represents alkyl; R.sup.7, R.sup.8 and R.sup.9 represent groups including H or OH, R.sup.10 has various significances including alkyl and alkenyl; X and Y represent groups including O and (H, OH); R.sup.14, R.sup.15, R.sup.16, R.sup.17, R.sup.18, R.sup.19, R.sup.22 and R.sup.23 represent H or alkyl; R.sup.20 and R.sup.21 represent groups including O, (H, OH) and (H, O-alkyl), n is 1, 2 or 3, and in addition, Y, R.sup.10 and R.sup.23, together with the carbon atoms to which they are attached, may represent a heterocyclic ring, (with certain provisos) are described. Processes for making the compounds and pharmaceutical formulations containing them, e.g. for use as immunosuppressive agents, are also described. ##STR1##

摘要翻译： PCT No.PCT / GB88 / 01093 Sec。 371日期：1989年7月25日 102（e）日期1989年7月25日PCT提交1988年12月2日PCT公布。 出版物WO89 / 05304 （I）化合物，其中[R 1和R 2]，[R 3和R 4]和[R 5和R 6]表示碳 - 碳键或两个氢原子; R2另外表示烷基; R7，R8和R9表示包括H或OH的基团，R10具有各种含义，包括烷基和烯基; X和Y表示包括O和（H，OH）的基团; R14，R15，R16，R17，R18，R19，R22和R23表示H或烷基; R 20和R 21表示包括O，（H，OH）和（H，O-烷基），n为1,2或3的基团，此外，Y，R 10和R 23与它们所连接的碳原子一起 可以表示杂环（具有一定条件）。 制备化合物和含有它们的药物制剂的方法，例如 也用作免疫抑制剂。