摘要:
A system for delivering a fluid comprising cells to tissue of a patient includes a container holding an injection fluid and a powered drive. A sensor system provides a measurement indicative of at least shear forces on the cells to a control system. Based at least in part on this measurement, the control system is adapted to transmit a control signal to the powered drive for pressurizing the contents of the container to deposit cells within the tissue of a patient via a fluid path and a patient interface. As an example, the cells can be pregenitor or stem cells.
摘要:
The present invention provides pressure measuring devices comprising a sensor to detect the force upon at least a portion of a contact surface of a syringe plunger during pressurization of a fluid medium within the syringe. A determination of the pressure of the fluid medium within the syringe is thereby enabled.
摘要:
A syringe interface includes a top opening into which a syringe can be loaded, a first retaining member positioned on one side of the opening and a second retaining member positioned on a second side of the opening. The first retaining member and the second retaining member abut a forward facing abutment surface of a syringe flange on the syringe generally symmetrically. The syringe interface further includes a cradle, at least one engagement member to abut a forward facing abutment surface of a syringe flange, and a carriage slidably disposed within the cradle. The carriage includes a connector to form a releasable connection with a plunger or plunger extension of the syringe and a drive member of the injector. The connector includes a plurality of flexing capture members that flex radially outward to connect to a flange on the rear of the plunger or plunger extension of the syringe when the carriage is moved forward within the syringe interface. The syringe interface may further include a connector on a rear portion thereof to connect to the injector.
摘要:
A system for connecting a conduit to a fluid path element, includes a length of conduit, a compressible sealing element positioned on a distal end of the length of conduit to be attached to the fluid path element, a first cooperating connector positioned around the length of conduit proximal to the sealing element and a second cooperating connector. The first cooperating connector includes a first cooperating connection mechanism and the second cooperating connector includes a second cooperating connection mechanism. The first cooperating connection mechanism and the second cooperating connection mechanism are adapted to form a connection between the first cooperating connector and the second cooperating connector. The connection causes the compression of the sealing element. The second cooperating connector further includes a passage therein in fluid connection with a connection for the fluid path element. Another system for connecting to a fluid path section includes a connector including a connection mechanism to connect the connector to the fluid path section and a passage therethrough. The passage is in fluid connection with a first fluid path element downstream of the connector. The first fluid path element includes a lumen therethrough. The diameter of the lumen is flared outward to a larger diameter at a proximal end of the fluid path element. The proximal end of the first fluid path element can abut a surface of the connector in which the distal end of the fluid path is formed. The inner diameter of the proximal end is greater than the diameter of the passage of the second cooperating connector. The outer diameter of the proximal end of the first fluid path element can also be flared outward
摘要:
A syringe plunger includes a wall having an inner surface and one or more inwardly projecting flanges disposed on the inner surface of the wall. Preferably, the inner surface of the wall defines a retaining shoulder formed along an axial plane thereof. An injector drive member preferably includes at least one retaining member adapted to engage the retaining shoulder of the syringe plunger to allow the drive member to retract the plunger with the body of the syringe. Further, the drive member preferably includes one or more outwardly extending flange members adapted to be engaged by the inwardly projecting flanges of the syringe plunger. When the syringe body is rotated, the at least one retaining member on the drive member is retracted and disengaged from the retaining shoulder of the syringe plunger.
摘要:
A syringe for use with a powered injector to inject a fluid into a patient inclides an encoder. The encoder includes at least a first indicator positioned on the encoder. The first indicator is adapted to interact with at least a portion of energy being propagated through or adjacent the encoder in a manner that is detectable. The presence (or absence) of the first indicator provides or corresponds to information about the syringe configuration. The indicator(s) of the present invention can, for example, provide information about syringe configuration by the number and/or position thereof. A plurality or set of such syringes can be provided, with the configuration of each such syringe being represented by the presence or absence of indicator(s) of that syringe.
摘要:
A fluid delivery system includes a source of an injection fluid including a source outlet. The system also includes a control system including a control system inlet in fluid connection with the source outlet, a control system outlet and, alternatively, an actuator. The control system is adapted to deliver a predetermined amount of fluid via the control system outlet upon activation of the actuator or modification of the control system. In several embodiments, the injection fluid in the source is pressurized. The source can, for example, include a plunger slidably disposed therein and a force application mechanism to place force upon the plunger and pressurize the fluid within the source. The control system can further include a metering volume in fluid connection with a valve system. The metering volume can include a plunger slidably disposed therein.
摘要:
An improved vascular reinforcing stent for use in angioplasty which comprises a sleeve tubular stent of a cross-linkable substance that is completely encapsulated within a biologically compatible film and a process for using such a stent.
摘要:
A bladder syringe for a fluid delivery system includes a cylindrical body, a cap-bladder assembly, a plunger element disposed in the cylindrical body, and a mounting assembly to secure the cap-bladder assembly to the cylindrical body. The cylindrical body has a distal end and a proximal end and defines a throughbore. The cap-bladder assembly is adapted for connection to the distal end of the cylindrical body, and includes a cap body and a bladder. The cap body defines an interior cavity and a distal discharge conduit and is adapted to engage the distal end of the cylindrical body. A disc-shaped bladder is disposed within the interior cavity and typically includes a central membrane portion. The plunger element is disposed in the throughbore of the cylindrical body and is vented to enable evacuation of the space between the plunger element and the cap-bladder assembly in the cylindrical body.
摘要:
A bladder syringe for a fluid delivery system includes a cylindrical body, a cap-bladder assembly, a plunger element disposed in the cylindrical body, and a mounting assembly to secure the cap-bladder assembly to the cylindrical body. The cylindrical body has a distal end and a proximal end and defines a throughbore. The cap-bladder assembly is adapted for connection to the distal end of the cylindrical body, and includes a cap body and a bladder. The cap body defines an interior cavity and a distal discharge conduit and is adapted to engage the distal end of the cylindrical body. A disc-shaped bladder is disposed within the interior cavity and typically includes a central membrane portion. The plunger element is disposed in the throughbore of the cylindrical body and is vented to enable evacuation of the space between the plunger element and the cap-bladder assembly in the cylindrical body.