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公开(公告)号：US07462166B2
公开(公告)日：2008-12-09
申请号：US10466418
申请日：2002-01-16
IPC分类号： A61M37/00
CPC分类号： A61M5/14546 , A61M5/14566 , A61M2205/6072
摘要： A syringe for use with a powered injector to inject a fluid into a patient inclides an encoder. The encoder includes at least a first indicator positioned on the encoder. The first indicator is adapted to interact with at least a portion of energy being propagated through or adjacent the encoder in a manner that is detectable. The presence (or absence) of the first indicator provides or corresponds to information about the syringe configuration. The indicator(s) of the present invention can, for example, provide information about syringe configuration by the number and/or position thereof. A plurality or set of such syringes can be provided, with the configuration of each such syringe being represented by the presence or absence of indicator(s) of that syringe.
摘要翻译： 用于与动力注射器一起使用以将流体注入患者的注射器包括编码器。 编码器至少包括位于编码器上的第一指示器。 第一指示符适于与以可检测的方式与正在传播或邻近编码器的能量的至少一部分相互作用。 第一个指示器的存在（或不存在）提供或对应于关于注射器配置的信息。 例如，本发明的指示器可以通过其数量和/或位置提供关于注射器构造的信息。 可以提供多个或一组这样的注射器，每个这样的注射器的构造由该注射器的指示器的存在或不存在表示。
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公开(公告)号：US07018363B2
公开(公告)日：2006-03-28
申请号：US09765498
申请日：2001-01-18
CPC分类号： G01D5/12 , A61M5/1452 , A61M5/3129 , A61M2005/3125 , A61M2205/6036 , A61M2205/6063
摘要： A syringe for use with a powered injector to inject a fluid into a patient that includes a length of material adapted to transmit or propagate electromagnetic energy therethrough. The length of material includes at least a first indicator positioned along the length of material. The first indicator is adapted to interact with at least a portion of the energy being propagated through the length of material in a manner that is detectable. The presence (or absence) of the first indicator provides or corresponds to information about the syringe configuration. The indicator(s) of the present invention can, for example, provide information about syringe configuration by the number and/or position thereof. A plurality or set of such syringes can be provided, with the configuration of each such syringe being represented by the presence or absence of indicator(s) of that syringe.
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公开(公告)号：US08821450B2
公开(公告)日：2014-09-02
申请号：US11254061
申请日：2005-10-19
CPC分类号： G01D5/12 , A61M5/1452 , A61M5/3129 , A61M2005/3125 , A61M2205/6036 , A61M2205/6063
摘要： A syringe for use with a powered injector to inject a fluid into a patient that includes a length of material adapted to transmit or propagate electromagnetic energy therethrough. The length of material includes at least a first indicator positioned along the length of material. The first indicator is adapted to interact with at least a portion of the energy being propagated through the length of material in a manner that is detectable. The presence (or absence) of the first indicator provides or corresponds to information about the syringe configuration. The indicator(s) of the present invention can, for example, provide information about syringe configuration by the number and/or position thereof. A plurality or set of such syringes can be provided, with the configuration of each such syringe being represented by the presence or absence of indicator(s) of that syringe.
摘要翻译： 一种与动力注射器一起使用的注射器，用于将流体注入患者体内，该注射器包括适于透过或传播电磁能量的一定长度的材料。 材料的长度至少包括沿材料长度定位的第一指示器。 第一指示符适于与以可检测的方式相互作用的能量的至少一部分通过材料的长度传播。 第一个指示器的存在（或不存在）提供或对应于关于注射器配置的信息。 例如，本发明的指示器可以通过其数量和/或位置提供关于注射器构造的信息。 可以提供多个或一组这样的注射器，每个这样的注射器的构造由该注射器的指示器的存在或不存在表示。
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公开(公告)号：US20090240197A1
公开(公告)日：2009-09-24
申请号：US12297637
申请日：2007-04-19
申请人： Kevin P. Cowan , Eugene A. Gelblum , Alan D. Hirschman , David M. Reilly , Edward J. Rhinehart , Frederick W. Trombley, III
发明人： Kevin P. Cowan , Eugene A. Gelblum , Alan D. Hirschman , David M. Reilly , Edward J. Rhinehart , Frederick W. Trombley, III
IPC分类号： A61M25/092 , A61M25/09 , A61M25/10
CPC分类号： A61M25/0125 , A61M25/0053 , A61M25/007 , A61M25/0082 , A61M25/0113 , A61M25/0116 , A61M25/0119 , A61M25/0122 , A61M2025/0058
摘要： Systems, devices, and methods towards improved diagnosis and therapy in connection with central venous catheters (including PICC lines). Included among the many improvements broadly contemplated herein are: arrangements via which a venous catheter can move passively into position in central venous circulation; arrangements via which a catheter can be actively guided without the use of a needle or guide wire; arrangements via which a catheter can be packaged to facilitate easy, rapid, and positionally accurate deployment by medical personnel while maintaining device sterility; and arrangements via which a catheter tip can be imaged during and after insertion.
摘要翻译： 与中心静脉导管（包括PICC系）相关的改进诊断和治疗的系统，装置和方法。 包括在这里广泛考虑的许多改进之中：静脉导管可以被动地移动到中心静脉循环中的位置的布置; 可以不使用针或引导线而可以主动地引导导管的布置; 导管可以被包装的布置，以便医疗人员容易，快速和定位准确的部署，同时保持装置不育; 以及在插入期间和之后可以使导管尖端成像的布置。
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公开(公告)号：US20080294096A1
公开(公告)日：2008-11-27
申请号：US12092448
申请日：2006-11-06
申请人： Arthur E. Uber, III , Alan D. Hirschman , Evan Facher , Eugene A. Gelblum , David M. Griffiths , Edward J. Rhinehart , David M. Reilly , Kevin P. Cowan , Page Cedarholm , Barry L. Tucker , Mark Trocki , David Mishler , Henry E. Bartony, JR. , Robert Parks
发明人： Arthur E. Uber, III , Alan D. Hirschman , Evan Facher , Eugene A. Gelblum , David M. Griffiths , Edward J. Rhinehart , David M. Reilly , Kevin P. Cowan , Page Cedarholm , Barry L. Tucker , Mark Trocki , David Mishler , Henry E. Bartony, JR. , Robert Parks
IPC分类号： A61M5/168
CPC分类号： A61M5/142 , A61M5/1452 , A61M5/1723 , A61M5/3291 , A61M25/007 , A61M25/04 , A61M31/005 , A61M2025/0089 , A61M2025/009 , A61M2025/0092
摘要： A system for delivering a fluid comprising cells to tissue of a patient, includes: a least a first container for holding an injection fluid in which the agent is carried; a first powered drive in operative connection with the container, the first powered drive being operable to pressurize contents of the container; a control system in operative connection with the first powered drive and operative to control the first powered drive; a fluid path in fluid connection with the container, the fluid path including a patient interface adapted to deposit the cells within tissue of the patient; a sensor system; and a communication system in connection with at least the control system and the sensor system. The communication system is adapted to provide information to the control system. The control system in adapted to transmit a control signal to at least the first powered drive based at least in part on information provided to the control system. The cells can for example be pregenitor cells or stem cells.
摘要翻译： 一种用于将包含细胞的流体输送到患者的组织的系统，包括：用于保持其中携带有药剂的注射液体的至少第一容器; 与容器操作性连接的第一动力驱动器，第一动力驱动器可操作以对容器的内容物进行加压; 控制系统，其与第一动力驱动器操作连接并且可操作以控制第一动力驱动; 与容器流体连接的流体路径，流体路径包括适于将细胞沉积在患者组织内的患者界面; 传感器系统; 以及至少与控制系统和传感器系统相关的通信系统。 通信系统适于向控制系统提供信息。 控制系统适于至少部分地基于提供给控制系统的信息将控制信号发送到至少第一动力驱动器。 细胞可以例如是前体细胞或干细胞。
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6.发明申请公开(公告)号：US20110178359A1
公开(公告)日：2011-07-21
申请号：US12595165
申请日：2007-12-28
申请人： Alan D. Hirschman , Arthur E. Uber, III , Kevin P. Cowan , David M. Reilly , Edward J. Rhinehart , John Kalafut , Bronwyn Uber , Frederick W. Trombley, III , Steven J. Remis , Paul D. Levin , Scott Griffith , Douglas Descalzi , Richard Dewit , David M. Griffiths
发明人： Alan D. Hirschman , Arthur E. Uber, III , Kevin P. Cowan , David M. Reilly , Edward J. Rhinehart , John Kalafut , Bronwyn Uber , Frederick W. Trombley, III , Steven J. Remis , Paul D. Levin , Scott Griffith , Douglas Descalzi , Richard Dewit , David M. Griffiths
IPC分类号： A61M36/06
CPC分类号： A61N5/1001 , A61B5/0205 , A61B5/055 , A61B5/7289 , A61B6/032 , A61B6/037 , A61B6/0478 , A61B6/107 , A61B6/4057 , A61B6/4258 , A61B6/4423 , A61B6/507 , A61B6/508 , A61B6/5288 , A61B6/548 , A61M5/007 , A61M5/14546 , A61M5/1456 , A61M5/16827 , A61M5/16881 , A61M5/1723 , A61M5/1785 , A61M2205/3576 , A61N5/1071 , A61N2005/1021 , A61N2005/1094 , G06F19/00 , G06F19/3468 , G16H20/17 , G21F5/015 , G21G4/08
摘要： An integrated radiopharmaceutical patient treatment system is disclosed including a patient support platform with an associated patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with a patient, and an integrated system controller operably associated with the patient stimulus apparatus, imager, radiopharmaceutical fluid delivery system, and patient monitor to control and coordinate their operations. Within the patient treatment system the radiopharmaceutical fluid delivery system may be included comprising a radionuclide supply module, a radiopharmaceutical processing module, a quality control module, a patient injection module, and a controller. A hazardous fluid handling system including a docking station and a hazardous fluid transport device adapted to detachably dock with the docking station is further disclosed.
摘要翻译： 公开了一种集成的放射性药物患者治疗系统，其包括具有相关联的患者刺激装置的患者支撑平台，靠近患者支撑平台的成像器，用于将放射性药物流体输入患者的放射性药物流体输送系统，与 患者以及与患者刺激装置，成像器，放射性药物流体输送系统和患者监护器可操作地相关联以控制和协调其操作的集成系统控制器。 在患者治疗系统内，可以包括放射性药物流体递送系统，包括放射性核素供应模块，放射性药物处理模块，质量控制模块，患者注射模块和控制器。 进一步公开了一种危险的流体处理系统，其包括对接站和适于与对接站可拆卸地对接的危险流体输送装置。
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公开(公告)号：US20130172811A1
公开(公告)日：2013-07-04
申请号：US13772849
申请日：2013-02-21
申请人： Arthur E. Uber, III , David M. Griffiths , David M. Reilly , Alan D. Hirschman , Kevin P. Cowan , Mark Trocki
发明人： Arthur E. Uber, III , David M. Griffiths , David M. Reilly , Alan D. Hirschman , Kevin P. Cowan , Mark Trocki
CPC分类号： A61M5/1407 , A61M5/14216 , A61M5/14236 , A61M5/1723 , A61M2202/09 , B01F7/00258 , B01F7/00566 , B01F7/00908 , B01F7/086 , B01F9/103 , B01F11/0071 , B01F11/0074 , B01F11/0082 , B01F11/025 , B01F13/002 , B01F13/0023 , B01F13/0818 , G06F19/00
摘要： A system for delivering a slurry to a patient includes a fluid, a material that is non-dissolvable or immiscible in the fluid, thereby forming a slurry, a container adapted to contain the slurry and a supernate of the slurry, the container defining an outlet through which the slurry is delivered to the patient, a fluidizing system associated with the container, a pressurizing mechanism adapted to create a pressure to cause the slurry contained within the container to flow for delivery to the patient and a control unit in communication with and adapted to control the fluidizing system and the pressurizing mechanism. The fluidizing system is adapted to effect dilation of the slurry while maintaining at least a portion of the supernate.
摘要翻译： 用于将浆料递送到患者的系统包括流体，在流体中不可溶或不混溶的材料，从而形成浆料，适于容纳浆料的容器和浆料的上清液，容器限定出口 通过其将浆料输送到患者，与容器相关联的流化系统，适于产生压力以使容纳在容器内的浆液流动以输送到患者的加压机构，以及与该患者连接并适应的控制单元 以控制流化系统和加压机构。 流化系统适于在保持至少一部分上清液的同时实现浆料的扩张。
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公开(公告)号：US08382704B2
公开(公告)日：2013-02-26
申请号：US11960968
申请日：2007-12-20
申请人： Arthur E. Uber, III , David M. Griffiths , David M. Reilly , Alan D. Hirschman , Kevin P. Cowan , Mark Trocki
发明人： Arthur E. Uber, III , David M. Griffiths , David M. Reilly , Alan D. Hirschman , Kevin P. Cowan , Mark Trocki
IPC分类号： A61M37/00
CPC分类号： A61M5/1407 , A61M5/14216 , A61M5/14236 , A61M5/1723 , A61M2202/09 , B01F7/00258 , B01F7/00566 , B01F7/00908 , B01F7/086 , B01F9/103 , B01F11/0071 , B01F11/0074 , B01F11/0082 , B01F11/025 , B01F13/002 , B01F13/0023 , B01F13/0818 , G06F19/00
摘要： A system for delivering a cell-slurry to a patient may include a fluid, cells that are non-dissolvable or immiscible in the fluid, thereby forming the cell-slurry, a syringe adapted to contain the cell-slurry and a supernate of the cell-slurry, the syringe defining a first end having an outlet through which the cell-slurry is delivered to the patient, a fluidizing system associated with the syringe and adapted to effect dilation of the cell-slurry with a portion of the supernate, to form a dilated cell-slurry, the dilated cell-slurry being transferred from the fluidizing system to the syringe, while maintaining at least a portion of the supernate, the cell-slurry and supernate being transferred from the fluidizing system to the syringe, a pressurizing mechanism adapted to create a pressure to cause the dilated cell-slurry contained within the syringe to flow for delivery to the patient and a control unit in communication with and adapted to control the fluidizing system, the pressurizing mechanism and movement of the dilated cell-slurry.
摘要翻译： 用于将细胞浆料递送到患者的系统可以包括流体，在流体中不可溶或不混溶的细胞，从而形成细胞浆液，适于容纳细胞浆液和细胞上清液的注射器 - 注射器限定具有出口的第一端，细胞浆料通过该出口传送到患者，与注射器相关联的适于用一部分上清液进行细胞浆液的扩张的流化系统，形成 扩张的细胞浆液，将扩张的细胞浆液从流化系统转移到注射器，同时保持至少一部分上清液，细胞浆液和上清液从流化系统转移到注射器，加压机构 适于产生压力以使得包含在注射器内的扩张的细胞浆液流动以传递给患者，以及与控制流化系统连通并适于控制流化系统的控制单元 扩散细胞浆的机制和运动。
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公开(公告)号：US08182444B2
公开(公告)日：2012-05-22
申请号：US12092448
申请日：2006-11-06
申请人： Arthur E. Uber, III , Alan D. Hirschman , David M. Griffiths , David M. Reilly , Kevin P. Cowan , Barry L. Tucker , David Mishler
发明人： Arthur E. Uber, III , Alan D. Hirschman , David M. Griffiths , David M. Reilly , Kevin P. Cowan , Barry L. Tucker , David Mishler
IPC分类号： A61M5/168
CPC分类号： A61M5/142 , A61M5/1452 , A61M5/1723 , A61M5/3291 , A61M25/007 , A61M25/04 , A61M31/005 , A61M2025/0089 , A61M2025/009 , A61M2025/0092
摘要： A system for delivering a fluid comprising cells to tissue of a patient includes a container holding an injection fluid and a powered drive. A sensor system provides a measurement indicative of at least shear forces on the cells to a control system. Based at least in part on this measurement, the control system is adapted to transmit a control signal to the powered drive for pressurizing the contents of the container to deposit cells within the tissue of a patient via a fluid path and a patient interface. As an example, the cells can be pregenitor or stem cells.
摘要翻译： 用于将包含细胞的流体输送到患者的组织的系统包括容纳注射流体和动力驱动器的容器。 传感器系统提供至少指示细胞上的至少剪切力到控制系统的测量。 至少部分地基于该测量，控制系统适于将控制信号传输到动力驱动器，用于对容器的内容物进行加压，以经由流体路径和患者接口将细胞沉积在患者组织内。 例如，细胞可以是祖细胞或干细胞。
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公开(公告)号：US20090012497A1
公开(公告)日：2009-01-08
申请号：US11960968
申请日：2007-12-20
申请人： Arthur E. Uber, III , David M. Griffiths , David M. Reilly , Alan D. Hirschman , Kevin P. Cowan , Mark Trocki
发明人： Arthur E. Uber, III , David M. Griffiths , David M. Reilly , Alan D. Hirschman , Kevin P. Cowan , Mark Trocki
CPC分类号： A61M5/1407 , A61M5/14216 , A61M5/14236 , A61M5/1723 , A61M2202/09 , B01F7/00258 , B01F7/00566 , B01F7/00908 , B01F7/086 , B01F9/103 , B01F11/0071 , B01F11/0074 , B01F11/0082 , B01F11/025 , B01F13/002 , B01F13/0023 , B01F13/0818 , G06F19/00
摘要： A system for delivering a slurry to a patient includes a fluid, a material that is non-dissolvable or immiscible in the fluid, thereby forming a slurry, a container adapted to contain the slurry and a supernate of the slurry, the container defining an outlet through which the slurry is delivered to the patient, a fluidizing system associated with the container, a pressurizing mechanism adapted to create a pressure to cause the slurry contained within the container to flow for delivery to the patient and a control unit in communication with and adapted to control the fluidizing system and the pressurizing mechanism. The fluidizing system is adapted to effect dilation of the slurry while maintaining at least a portion of the supernate.
摘要翻译： 用于将浆料递送到患者的系统包括流体，在流体中不可溶或不混溶的材料，从而形成浆料，适于容纳浆料的容器和浆料的上清液，容器限定出口 通过其将浆料输送到患者，与容器相关联的流化系统，适于产生压力以使容纳在容器内的浆液流动以输送到患者的加压机构，以及与该患者连接并适应的控制单元 以控制流化系统和加压机构。 流化系统适于在保持至少一部分上清液的同时实现浆料的扩张。
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