公开(公告)号：US20180143925A1

公开(公告)日：2018-05-24

申请号：US15572777

申请日：2016-04-27

Applicant: MEDTRONIC, INC.

Inventor： Robert Hocken ,  Wesley A. Santa ,  Christopher M. Arnett ,  Jalpa S. Shah ,  Joel E. Sivula

IPC: G06F13/28 ,  A61N1/36

CPC classification number: G06F13/28 ,  A61N1/36146 ,  A61N1/37235 ,  G11C16/12 ,  H03K3/64

Abstract: A hardware based block moving controller of an active device such as an implantable medical device that provides electrical stimulation reads a parameter data from a block of memory and then writes the parameter data to a designated register set of a component that performs an active function. The block of memory may include data that specifies a size of the block of memory to be moved to the register set. The block of memory may also include data that indicates a number of triggers to skip before moving a next block of memory to the register set. A trigger that causes the block moving controller to move the data from the block of memory to the register set may be generated in various ways such as through operation of the component having the register set or by a separate timer.

公开(公告)号：US09724521B2

公开(公告)日：2017-08-08

申请号：US14682855

申请日：2015-04-09

Applicant: Medtronic, Inc.

Inventor： Peng Cong ,  Timothy J. Denison ,  Gabriela C. Molnar ,  Forrest C. M. Pape ,  Scott R. Stanslaski ,  Wesley A. Santa

IPC: A61N1/36 ,  A61N1/372

CPC classification number: A61N1/372 ,  A61N1/36171 ,  A61N1/37252

Abstract: In some examples, one or more processors determine characteristics of frequency components of a sensed bioelectrical signal. In response to determining the characteristics, the one or more processors determine therapy parameters for frequency components of a stimulation signal. The one or more processors may determine the therapy parameters based on the characteristics of the frequency components of the sensed bioelectrical signal. As another example, the one or more processors may determine the therapy parameters based on received information after the characteristics of the frequency components of the sensed bioelectrical signal are displayed to a user.

公开(公告)号：US20150375006A1

公开(公告)日：2015-12-31

申请号：US14732408

申请日：2015-06-05

Applicant: Medtronic, Inc.

Inventor： Timothy J. Denison ,  Kunal Paralikar ,  Gordon Orvis Munns ,  Wesley A. Santa ,  Peng Cong ,  Christian S. Nielsen ,  John D. Norton ,  John G. Keimel

IPC: A61N5/06

CPC classification number: A61N5/0601 ,  A61B2017/00084 ,  A61B2018/00839 ,  A61M5/14276 ,  A61N1/086 ,  A61N1/365 ,  A61N5/062 ,  A61N5/0622 ,  A61N2005/0612 ,  A61N2005/0626 ,  A61N2005/063 ,  A61N2005/0651

Abstract: A method for delivering optical stimulation comprises transfecting a target tissue with a light-sensitive channel protein sensitive to light in a wavelength range, delivering light in the wavelength range to the target tissue via an optical stimulation device, substantially simultaneously with delivering light to the target tissue, sensing bioelectric signals, determining a patient therapeutic state based on the bioelectric signals, and adjusting the delivery of the light to the target tissue based on the sensed patient therapeutic state.

Abstract translation: 用于递送光学刺激的方法包括用对波长范围内的光敏感的光敏通道蛋白转染靶组织，通过光学刺激装置将波长范围内的光传送到目标组织，基本上同时将光传递到靶 组织，感测生物电信号，基于生物电信号确定患者治疗状态，以及基于感测到的患者治疗状态来调整到目标组织的光的传送。

公开(公告)号：US20150119751A1

公开(公告)日：2015-04-30

申请号：US14064801

申请日：2013-10-28

Applicant: Medtronic, Inc.

Inventor： Scott R. Stanslaski ,  Peng Cong ,  Wesley A. Santa ,  Timothy J. Denison

IPC: A61B5/04 ,  A61N1/36

CPC classification number: A61B5/04001 ,  A61B5/40 ,  A61B5/4836 ,  A61B5/7217 ,  A61B5/7225 ,  A61N1/36 ,  A61N1/3605 ,  A61N1/36125

Abstract: Devices and methods provide for the sensing of physiological signals during stimulation therapy by preventing stimulation waveform artifacts from being passed through to the amplification of the sensed physiological signal. Thus, the amplifiers are not adversely affected by the stimulation waveform and can provide for successful sensing of physiological signals between stimulation waveform pulses. A blanking switch may be used to blank the stimulation waveform artifacts where the blanking switch is operated in a manner synchronized with the stimulation waveform so that conduction in the sensing path is blocked during the stimulation pulse as well as during other troublesome artifacts such as a peak of a recharge pulse. A limiter may be used to limit the amplitude of the sensed signal, and hence the stimulation artifacts, that are passed to the amplifier without any synchronization of the limiter to the stimulation waveform.

Abstract translation: 装置和方法通过防止刺激波形伪影通过到感测的生理信号的放大来提供在刺激治疗期间感测生理信号。 因此，放大器不受刺激波形的不利影响，并且可以提供刺激波形脉冲之间的生理信号的成功感测。 消隐开关可以用于消除刺激波形伪影，其中消隐开关以与刺激波形同步的方式操作，使得感测路径中的传导在刺激脉冲期间以及在其他麻烦的伪像期间被阻塞，例如峰值 的充电脉冲。 可以使用限制器来限制感测信号的幅度，并且因此限制器将刺激伪影传递到放大器而不限制器与刺激波形的任何同步。