公开(公告)号：US5907069A

公开(公告)日：1999-05-25

申请号：US9510

申请日：1998-01-20

Applicant: Brian F. Becnel ,  Mahmood Sabahi ,  Kevin J. Theriot

Inventor： Brian F. Becnel ,  Mahmood Sabahi ,  Kevin J. Theriot

IPC: B01J31/24 ,  B01J31/34 ,  C07B61/00 ,  C07C37/00 ,  C07C39/38 ,  C07C41/16 ,  C07C41/42 ,  C07C43/225 ,  C07C45/00 ,  C07C45/51 ,  C07C45/62 ,  C07C45/68 ,  C07C45/69 ,  C07C45/74 ,  C07C47/575 ,  C07C49/255 ,  C07C39/14 ,  C07C41/00 ,  C07C47/52

CPC classification number: C07C49/255 ,  C07C37/00 ,  C07C41/16 ,  C07C41/34 ,  C07C41/40 ,  C07C41/42 ,  C07C45/004 ,  C07C45/512 ,  C07C45/62 ,  C07C45/68 ,  C07C45/74 ,  C07C47/575

Abstract: In producing nabumetone or precursor thereof, use is made of 2-bromo-6-methoxynaphthalene formed by (a) methylating 6-bromo-2-naphthol with methyl bromide or methyl chloride, in a halogen-free liquid solvent comprising at least about 40% by weight of one or more compounds of the formula RZ where R is a hydrogen atom or an alkyl group, and Z is a hydroxyl group or a cyanide group with the proviso that if Z is a cyanide group, R is an alkyl group, and in the presence of at least one strong base; and (b) recovering and purifying 2-bromo-6-methoxynaphthalene so formed. The 6-bromo-2-naphthol in turn is preferably formed by reacting 1,6-dibromo-2-naphthol with hydrogen in a halogen-containing liquid solvent comprising at least about 50% by weight of (A) at least one liquid organic halide solvent in which the halogen content has an atomic number of 35 or less or (B) a mixture of water and at least one such liquid organic halide solvent, and in the presence of catalytic amounts of (i) a tungsten carbide-based catalyst, and (ii) at least one phase transfer catalyst, most preferably while purging HBr from the reaction mixture as it is formed. In this way, the quantities of by-products formed in the overall operation are reduced, the need for use of excess iron and/or dimethyl sulfate as reaction components is avoided, and the overall efficiency of plant operation is improved especially when conducted on a large scale.

Abstract translation: 在制备萘布酮或其前体时，使用通过（a）在含卤素的液体溶剂中将6-溴-2-萘酚与甲基溴或甲基氯甲基化形成的2-溴-6-甲氧基萘，所述无卤液体溶剂包含至少约40 重量％的一种或多种式RZ化合物，其中R是氢原子或烷基，Z是羟基或氰基，条件是如果Z是氰基，则R是烷基， 并且在至少一个强碱的存在下; 和（b）回收和纯化如此形成的2-溴-6-甲氧基萘。 优选6-溴-2-萘酚通过在含卤素的液体溶剂中使1,6-二溴-2-萘酚与氢反应形成，该溶剂包含至少约50重量％的（A）至少一种液体有机物 卤素溶剂，其中卤素含量为35或更小的原子序数或（B）水和至少一种这样的液体有机卤化物溶剂的混合物，并且在催化量（i）碳化钨基催化剂 ，和（ii）至少一种相转移催化剂，最优选当其形成时从反应混合物中吹扫HBr。 以这种方式，减少了在整个操作中形成的副产物的数量，避免了使用过量的铁和/或硫酸二甲酯作为反应组分的需要，并且特别是当在 大规模

公开(公告)号：US5817888A

公开(公告)日：1998-10-06

申请号：US871708

申请日：1997-06-09

Applicant: Hassan Y. Elnagar ,  Robert L. Davis ,  Mahmood Sabahi

Inventor： Hassan Y. Elnagar ,  Robert L. Davis ,  Mahmood Sabahi

IPC: C07B39/00 ,  C07C37/62 ,  C07C41/22 ,  C07D233/82 ,  C07C41/24

CPC classification number: C07B39/00 ,  C07C37/62 ,  C07C41/22 ,  C07D233/82

Abstract: A bromination process for organic compounds employs stabilized bromine chloride solutions as the brominating agent. Activated aromatic compounds such as anisole can be selectively monobrominated in the para-position in high purity and yield.

Abstract translation: 有机化合物的溴化方法使用稳定的溴化氯溶液作为溴化剂。 活性芳族化合物如苯甲醚可以在高纯度和高产率的对位选择性单溴化。

公开(公告)号：US20110124540A1

公开(公告)日：2011-05-26

申请号：US13003745

申请日：2009-07-13

Applicant: Mahmood Sabahi

Inventor： Mahmood Sabahi

IPC: C10M135/28 ,  C07C319/22 ,  C07C319/20 ,  C10L1/24

CPC classification number: C10L1/2412 ,  C07C319/20 ,  C07C319/22 ,  C07C323/18 ,  C09K15/14 ,  C09K15/28 ,  C10M135/30 ,  C10M2219/087 ,  C10N2230/04 ,  C10N2230/10

Abstract: Described are multi-ring antioxidant products comprising at least one sulfur-bridged aromatic hydrocarbon compound substituted on at least one of its aromatic rings by at least one sterically hindered 3,5-dihydrocarbyl-4-hydroxybenzyl moiety. Such products have the formula: R—Sn—R[—S—R]m wherein each R is, independently, an aromatic hydrocarbon group having 6-12 carbon atoms, wherein m is 0-20, wherein n is 1-6 when m is 0, and when n is 1, m is 1-20; and wherein at least one of R, R1, and R2 is substituted by at least one such sterically hindered moiety. The preparation of such products and their use as antioxidants in compositions normally susceptible to oxidative degradation in oxygen or air, e.g., liquid fuel and lubricants, are also described.

Abstract translation: 描述的是多环抗氧化剂产物，其包含至少一个由至少一个空间位阻的3,5-二烃基-4-羟基苄基部分在至少一个芳族环上被取代的硫桥连的芳族烃化合物。 这些产物具有下式：R-Sn-R [-S-R] m，其中每个R独立地为具有6-12个碳原子的芳族烃基，其中m为0-20，其中n为1-6，当 m为0，当n为1时，m为1-20; 并且其中R，R 1和R 2中的至少一个被至少一个这样的空间位阻部分取代。 还描述了这样的产物的制备及其作为抗氧化剂在通常易于氧气或空气中的氧化降解的组合物中的用途，例如液体燃料和润滑剂。

公开(公告)号：US20100041730A1

公开(公告)日：2010-02-18

申请号：US12444181

申请日：2007-10-17

Applicant: Mahmood Sabahi ,  Vincent J. Gatto ,  Hassan Y. Elnagar

Inventor： Mahmood Sabahi ,  Vincent J. Gatto ,  Hassan Y. Elnagar

IPC: A61K31/4025 ,  A61K31/381 ,  A61K31/341 ,  C07D401/06 ,  C07D409/06 ,  C07D407/06

CPC classification number: C07C213/08 ,  C07C39/16 ,  C07D307/42 ,  C07D333/16 ,  C07D333/18 ,  C08K5/18 ,  C10M149/14 ,  C10M159/12 ,  C10M2207/026 ,  C10M2215/064 ,  C10N2230/10 ,  C07C215/74

Abstract: This invention relates to novel macromolecular compositions having oxidation inhibition characteristics that are exhibited when added to organic material normally susceptible to oxidative degradation in the presence of air or oxygen, such a petroleum products, synthetic polymers, and elastomeric substances.

Abstract translation: 本发明涉及具有氧化抑制特性的新型大分子组合物，当添加到在空气或氧气存在下通常易于氧化降解的有机材料（例如石油产品，合成聚合物和弹性体物质）时，其表现出来。

公开(公告)号：US07288677B2

公开(公告)日：2007-10-30

申请号：US11390777

申请日：2006-03-27

Applicant: John Y. Lee ,  Paul L. Wiggins ,  Judit Orgad ,  Mahmood Sabahi ,  Vernon O. Brandt

Inventor： John Y. Lee ,  Paul L. Wiggins ,  Judit Orgad ,  Mahmood Sabahi ,  Vernon O. Brandt

IPC: C07C249/00 ,  C07C251/00 ,  C07C257/00 ,  C07C263/00 ,  C07C265/00 ,  C07C267/00 ,  C07C291/00

CPC classification number: C07C211/12 ,  C07C211/51 ,  C08G18/10 ,  C08G18/3234 ,  C08G18/324 ,  C08G18/325 ,  C08G18/5024 ,  C08G18/6685 ,  C08G18/7671 ,  Y02P20/582

Abstract: This invention provides aromatic diimines which have imino hydrocarbylidene groups with at least two carbon atoms, and aromatic secondary diamines which have amino hydrocarbyl groups with at least two carbon atoms. Both the aromatic diimines and the aromatic secondary diamines either are in the form of one phenyl ring, or are in the form of two phenyl rings connected by an alkylene bridge; each position ortho to an imino group or an amino group bears a hydrocarbyl group. When in the form of one phenyl ring, there are two imino groups on the ring or two amino groups on the ring; the imino groups or amino groups are meta or para relative to each other. When in the form of two phenyl rings connected by an alkylene bridge, there is either one imino group or one amino group on each phenyl ring. Also provided are processes for forming diimines and secondary diamines.

Abstract translation: 本发明提供具有至少两个碳原子的亚氨基亚烃基的芳族二亚胺和具有至少两个碳原子的氨基烃基的芳族仲二胺。 芳族二亚胺和芳族仲胺都是一个苯环的形式，或者是由亚烷基桥连接的两个苯环的形式; 亚氨基或氨基的邻位各为一个烃基。 当以一个苯环的形式，环上有两个亚氨基或环上两个氨基; 亚氨基或氨基相对于彼此是间位或对位的。 当以亚烷基桥连接的两个苯环的形式，每个苯环上有一个亚氨基或一个氨基。 还提供了形成二亚胺和仲二胺的方法。

公开(公告)号：US6121500A

公开(公告)日：2000-09-19

申请号：US254334

申请日：1999-03-04

Applicant: Mahmood Sabahi

Inventor： Mahmood Sabahi

IPC: C07C37/00 ,  C07C45/00 ,  C07C45/62 ,  C07C45/68 ,  C07C45/74 ,  C07C49/255 ,  C07C37/02

CPC classification number: C07C49/255 ,  C07C37/00 ,  C07C45/00 ,  C07C45/62 ,  C07C45/68 ,  C07C45/74

Abstract: A mixture of water and a glycol, such as ethylene glycol, is employed as the solvent for the reaction between 1,6-dibromo-2-naphthol and an alkali metal sulfite in the preparation of 6-bromo-2-naphthol and its derivatives to effect a substantial reduction in reaction time. The glycol/water mol ratio is ordinarily in the range of 0.1-0.5/1, preferably 0.3/0.5/1.

Abstract translation: PCT No.PCT / US96 / 14765 Sec。 371 1999年3月4日第 102（e）1999年3月4日PCT PCT 1996年9月13日PCT公布。 第WO98 / 11040号公报 日期1998年3月19日使用水和乙二醇如乙二醇的混合物作为1,6-二溴-2-萘酚和碱金属亚硫酸盐之间的反应溶剂，制备6-溴-2 - 萘酚及其衍生物，以显着降低反应时间。 二醇/水摩尔比通常在0.1-0.5 / 1，优选为0.3 / 0.5 / 1的范围内。

公开(公告)号：US5840996A

公开(公告)日：1998-11-24

申请号：US854131

申请日：1997-05-08

Applicant: Mahmood Sabahi

Inventor： Mahmood Sabahi

IPC: C07C41/22

CPC classification number: C07C41/22

Abstract: Bromine is generated in situ in a mixture formed by mixing together 2-methoxynaphthalene, hydrogen bromide, at least one peroxidic compound and a chemically indifferent organic liquid solvent or diluent under conditions effective to produce 1,6-dibromo-2-methoxynaphthalene. Optionally, but preferably, water is also included in the mixture. Regioselective hydrodebromination of 1,6-dibromo-2-methoxynaphthalene with hydrogen and tungsten carbide enables production of 2-bromo-6-methoxynaphthalene.

Abstract translation: 在有效产生1,6-二溴-2-甲氧基萘的条件下，将2-甲氧基萘，溴化氢，至少一种过氧化合物和化学无关的有机液体溶剂或稀释剂混合在一起形成的混合物中原位生成溴。 任选地，但优选地，水也包括在混合物中。 1,6-二溴-2-甲氧基萘与氢和碳化钨的区域选择性加氢脱溴能够生产2-溴-6-甲氧基萘。

公开(公告)号：US5756851A

公开(公告)日：1998-05-26

申请号：US731806

申请日：1996-10-21

Applicant: Brian F. Becnel ,  Mahmood Sabahi ,  Kevin J. Theriot

Inventor： Brian F. Becnel ,  Mahmood Sabahi ,  Kevin J. Theriot

IPC: B01J31/24 ,  B01J31/34 ,  C07B61/00 ,  C07C37/00 ,  C07C39/38 ,  C07C41/16 ,  C07C41/42 ,  C07C43/225 ,  C07C45/00 ,  C07C45/51 ,  C07C45/62 ,  C07C45/68 ,  C07C45/69 ,  C07C45/74 ,  C07C47/575 ,  C07C49/255 ,  C07C49/115 ,  C07C41/00

CPC classification number: C07C49/255 ,  C07C37/00 ,  C07C41/16 ,  C07C41/34 ,  C07C41/40 ,  C07C41/42 ,  C07C45/004 ,  C07C45/512 ,  C07C45/62 ,  C07C45/68 ,  C07C45/74 ,  C07C47/575

Abstract: In producing nabumetone or precursor thereof, use is made of 2-bromo-6-methoxynaphthalene formed by (a) methylating 6-bromo-2-naphthol with methyl bromide or methyl chloride, in a halogen-free liquid solvent comprising at least about 40% by weight of one or more compounds of the formula RZ where R is a hydrogen atom or an alkyl group, and Z is a hydroxyl group or a cyanide group with the proviso that if Z is a cyanide group, R is an alkyl group, and in the presence of at least one strong base; and (b) recovering and purifying 2-bromo-6-methoxynaphthalene so formed. The 6-bromo-2-naphthol in turn is preferably formed by reacting 1,6-dibromo-2-naphthol with hydrogen in a halogen-containing liquid solvent comprising at least about 50% by weight of (A) at least one liquid organic halide solvent in which the halogen content has an atomic number of 35 or less or (B) a mixture of water and at least one such liquid organic halide solvent, and in the presence of catalytic amounts of (i) a tungsten carbide-based catalyst, and (ii) at least one phase transfer catalyst, most preferably while purging HBr from the reaction mixture as it is formed. In this way, the quantities of by-products formed in the overall operation are reduced, the need for use of excess iron and/or dimethyl sulfate as reaction components is avoided, and the overall efficiency of plant operation is improved especially when conducted on a large scale.

Abstract translation: 在制备萘布酮或其前体时，使用通过（a）在含卤素的液体溶剂中将6-溴-2-萘酚与甲基溴或甲基氯甲基化形成的2-溴-6-甲氧基萘，所述无卤液体溶剂包含至少约40 重量％的一种或多种式RZ化合物，其中R是氢原子或烷基，Z是羟基或氰基，条件是如果Z是氰基，则R是烷基， 并且在至少一个强碱的存在下; 和（b）回收和纯化如此形成的2-溴-6-甲氧基萘。 优选6-溴-2-萘酚通过在含卤素的液体溶剂中使1,6-二溴-2-萘酚与氢反应形成，该溶剂包含至少约50重量％的（A）至少一种液体有机物 卤素溶剂，其中卤素含量为35或更小的原子序数或（B）水和至少一种这样的液体有机卤化物溶剂的混合物，并且在催化量（i）碳化钨基催化剂 ，和（ii）至少一种相转移催化剂，最优选当其形成时从反应混合物中吹扫HBr。 以这种方式，减少了在整个操作中形成的副产物的数量，避免了使用过量的铁和/或硫酸二甲酯作为反应组分的需要，并且特别是当在 大规模。

公开(公告)号：US5683618A

公开(公告)日：1997-11-04

申请号：US593153

申请日：1996-02-01

Applicant: Mahmood Sabahi

Inventor： Mahmood Sabahi

IPC: C07C67/347 ,  C10M105/36 ,  C10M105/56 ,  C10M171/00 ,  C09K5/04 ,  C10M105/20

CPC classification number: C10M171/008 ,  C07C67/347 ,  C10M105/36 ,  C10M105/56 ,  C10M2207/281 ,  C10M2207/282 ,  C10M2207/283 ,  C10M2207/286 ,  C10M2211/022 ,  C10M2211/06 ,  C10M2215/16 ,  C10N2240/00 ,  C10N2240/22 ,  C10N2240/30 ,  C10N2240/50 ,  C10N2240/52 ,  C10N2240/54 ,  C10N2240/56 ,  C10N2240/58 ,  C10N2240/60 ,  C10N2240/66

Abstract: Lubricants having a viscosity suitable for a refrigeration lubricant as well as good miscibility with common refrigerants (including R-134a) comprise at least one oil corresponding to the formula Z--C(E)(E').sub.p --Q.sub.s in which Z is alkyl, cycloalkyl, or --(CTT'--CT"G).sub.w --CTT'--CHT"G; Q is --(CTT'--CT"G).sub.t --CTT'--CHT"G; T, T', and T" are independently selected from hydrogen G', and organic groups containing up to 20 carbons; E, E', G, and G' are independently selected from --COOR, --C(O)R', and --CN electron withdrawing groups wherein R and R' represent hydrocarbyls containing 1-30 carbons, with the proviso that at least about 50% of the electron withdrawing groups are --COOR; p is zero or one; s is respectively two or one; and each of t and w represents zero or a positive integer.

Abstract translation: 具有适用于制冷润滑剂的粘度以及与普通制冷剂（包括R-134a）良好混溶性的润滑剂包含至少一种对应于式ZC（E）（E'）p-Qs的油，其中Z是烷基，环烷基 ，或 - （CTT'-CT'G）w-CTT'-CHT''G; Q是 - （CTT'-CT''G）t-CTT'-CHT''G; T，T'和T“独立地选自氢G'和含有至多20个碳的有机基团; E，E'，G和G'独立地选自-COOR，-C（O）R'和-CN吸电子基团，其中R和R'代表含有1-30个碳的烃基，条件是至少 约50％的吸电子基团是-COOR; p为零或一; s分别是两个或一个; t和w中的每一个代表零或正整数。

公开(公告)号：US5648018A

公开(公告)日：1997-07-15

申请号：US555938

申请日：1995-11-13

Applicant: Mahmood Sabahi

Inventor： Mahmood Sabahi

IPC: C09K5/04 ,  C10M169/04 ,  C10M171/00 ,  C10M129/72

CPC classification number: C09K5/045 ,  C10M169/041 ,  C10M171/008 ,  C09K2205/24 ,  C10M2205/00 ,  C10M2205/028 ,  C10M2207/281 ,  C10M2207/282 ,  C10M2207/2825 ,  C10M2207/283 ,  C10M2207/2855 ,  C10M2207/286 ,  C10M2207/34 ,  C10M2211/022 ,  C10M2211/06 ,  C10N2220/02 ,  C10N2240/00 ,  C10N2240/22 ,  C10N2240/30 ,  C10N2240/50 ,  C10N2240/52 ,  C10N2240/54 ,  C10N2240/56 ,  C10N2240/58 ,  C10N2240/60 ,  C10N2240/66

Abstract: Hydrogenated oligomers of C.sub.4 -C.sub.20 .alpha.-olefins are used in minor amounts to improve the lubricity of ester oils corresponding to the formula ROOC--CH.sub.2 CH.sub.2 --(ROOC--CHCH.sub.2).sub.m --C(COOR).sub.2 --(CH.sub.2 CHCOOR).sub.n --CH.sub.2 CH.sub.2 COOR in which the R's represent alkyl groups of 1-30 carbons, each of m and n is zero or a positive integer, and the sum of m and n in the molecules is an average of 0-30. The improved ester oils are particularly valuable for use as lubricants in refrigeration compositions containing fluorohydrocarbon refrigerants.

Abstract translation: 使用C4-C20α-烯烃的氢化低聚物用于改善对应于式ROOC-CH2CH2-（ROOC-CHCH2）mC（COOR）2-（CH2CHCOOR）n-CH2CH2COOR的酯油的润滑性，其中R' 表示1-30个碳原子的烷基，m和n各自为零或正整数，分子中m和n的和平均为0-30。 改进的酯油对于在含氟烃制冷剂的制冷组合物中用作润滑剂是特别有价值的。