公开(公告)号：US20050234125A1

公开(公告)日：2005-10-20

申请号：US10517977

申请日：2003-06-18

申请人： Martin Eberle ,  Daniel Stierli ,  Urs Muller

发明人： Martin Eberle ,  Daniel Stierli ,  Urs Muller

IPC分类号： A01N41/06 ,  A01N41/10 ,  A01N43/16 ,  A01N43/36 ,  A01N43/40 ,  A01N43/42 ,  A01N43/50 ,  A01N43/54 ,  A01N43/56 ,  A01N43/60 ,  A01N43/653 ,  A01N43/78 ,  A01N43/824 ,  A01N43/836 ,  A01N47/16 ,  A01N47/38 ,  C07C303/38 ,  C07C303/40 ,  C07C311/13 ,  C07C317/20 ,  C07C323/20 ,  C07D207/26 ,  C07D207/27 ,  C07D213/30 ,  C07D213/64 ,  C07D213/643 ,  C07D213/74 ,  C07D213/85 ,  C07D215/20 ,  C07D231/12 ,  C07D233/54 ,  C07D233/60 ,  C07D239/26 ,  C07D239/42 ,  C07D239/46 ,  C07D239/60 ,  C07D241/42 ,  C07D249/08 ,  C07D271/10 ,  C07D277/20 ,  C07D277/24 ,  C07D277/34 ,  C07D277/36 ,  C07D277/42 ,  C07D285/08 ,  C07D285/12 ,  C07D295/18 ,  C07D295/205 ,  C07D295/215 ,  C07D311/16 ,  A01N37/34 ,  C07C317/32

CPC分类号： C07D207/27 ,  A01N41/06 ,  A01N43/36 ,  A01N43/40 ,  A01N43/50 ,  A01N43/56 ,  A01N43/653 ,  A01N43/78 ,  C07C311/13 ,  C07C317/20 ,  C07C323/20 ,  C07D213/30 ,  C07D213/643 ,  C07D213/85 ,  C07D231/12 ,  C07D233/54 ,  C07D239/26 ,  C07D239/42 ,  C07D239/60 ,  C07D241/42 ,  C07D249/08 ,  C07D271/10 ,  C07D277/24 ,  C07D277/34 ,  C07D277/36 ,  C07D277/42 ,  C07D285/08 ,  C07D285/12 ,  C07D295/205 ,  C07D295/215

摘要： The invention relates to α-sulfonylamino-acetonitrile derivatives of the general formula (I) including the optical isomers thereof and mixtures of such isomers, wherein Ar1, and Ar2 independently of each other stand for an optionally substituted aryl or heteroaryl group, R1, and R2 stand independently of each other for hydrogen, optionally substituted C1,-C5alkyl, optionally substituted C2-C5alkenyl, C2-C5alkynyl or optionally substituted C3-C6cycloalkyl; R3 designates hydrogen, C3-C5alkenyl, C3-C5alkynyl or optionally substituted C1,-C5alkyl; R4 is optionally substituted C1,-C5alkyl, optionally substituted C2-C5alkenyl, C2-C5alkynyl or optionally substituted C3-C6cycloalkyl; R5 and R6 are independently of each other hydrogen or optionally substituted C1-C5alkyl, optionally substituted C2-C5alkenyl, C2-C5alkynyl or optionally substituted C3-C6cycloalkyl; R7, and R8 are independently of each other hydrogen or optionally substituted C1,-C5alkyl, optionally substituted C2-C5alkenyl, C2-C5alkynyl or optionally substituted C3-C6cycloalkyl; W designates a bridge selected from —O— —S(O)m- or —NR3—; X designates a direct bond or a bridge selected from —O—, —S(O)m- or —NR3—; a and b independently of each other stand for a number 1, 2 or 3; and c and m independently of each other stand for a number zero, 1 or 2. These compounds possess useful plant protecting properties and may advantageously be employed in agricultural practice for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi.

公开(公告)号：US5190945A

公开(公告)日：1993-03-02

申请号：US794537

申请日：1991-11-19

申请人： Wolfgang Eckhardt ,  Urs Muller

发明人： Wolfgang Eckhardt ,  Urs Muller

IPC分类号： A01N43/54 ,  A01N43/60 ,  C07D409/12

CPC分类号： C07D409/12 ,  A01N43/54 ,  A01N43/60

摘要： 2-(Pyrimidyl or pyrazinyl)-imino-1,3-dithietanes ##STR1## wherein Ar is one of the radicals ##STR2## R is unsubstituted C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.3 alkyl which is substituted by halogen, C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 alkoxy, C.sub.1 -C.sub.3 alkylthio or cyano, independently of one another, or is unsubstituted or halo-substituted C.sub.3 -C.sub.7 alkenyl, unsubstituted or halo-substituted C.sub.3 -C.sub.7 alkynyl, or C.sub.3 -C.sub.5 cycloalkyl, C.sub.1 -C.sub.3 alkoxy, C.sub.1 -C.sub.3 alkylamino, nitro or halogen,n is a number from 0 to 3,X.sub.1 and X.sub.2 independently of each other are hydrogen or halogen, including the addition salts formed with acids of the formula H.sup..sym. X.sup..crclbar. in which the anion X.sup..crclbar. is Cl.sup..crclbar., Br.sup..crclbar., I.sup..crclbar., HSO.sub.4 -, H.sub.2 PO.sub.4 -, H.sub.2 PO.sub.3 -, NO.sub.3 -, CH.sub.3 COO.sup..crclbar., CH.sub.2 ClCOO-, CF.sub.3 COO-, HOCH.sub.2 COO-, CH.sub.3 CH(OH)COO.sup..crclbar., HOOCCOO.sup..crclbar., HOOCCH.sub.2 COO.sup..crclbar., HOOCCH.dbd.CHCOO.sup..crclbar., ##STR3## a process for the preparation of the compounds of formula I, and novel intermediates of the preparation process are described.The compounds of formula I have nematicidal and fungicidal properties. Nematicidal and fungicidal compositions that contain at least one compound of formula I as active ingredient, and also methods of using the compounds and the compositions in the control of nematodes and fungi, are described.

摘要翻译： 2-（嘧啶基或吡嗪基） - 亚氨基-1,3-二硫代环己基（I）其中Ar是基团之一R是未被取代的C 1 -C 3烷基或被卤素取代的C 1 -C 3烷基， C 1 -C 3烷基，C 1 -C 3烷氧基，C 1 -C 3烷硫基或氰基，彼此独立地是未取代的或卤素取代的C 3 -C 7链烯基，未取代或卤素取代的C 3 -C 7炔基或C 3 -C 5环烷基，C 1 -C 3烷氧基， C 3烷基氨基，硝基或卤素，n为0至3的数，X 1和X 2彼此独立地为氢或卤素，包括与式H（+）X（ - ）的酸形成的加成盐，其中阴离子X （ - ）为Cl（ - ），Br（ - ），I（ - ），HSO4-，H2PO4-，H2PO3-，NO3-，CH3COO（ - ），CH2ClCOO-，CF3COO-，HOCH2COO-，CH3CH （ - ），HOOCCOO（ - ），HOOCCH2COO（ - ），HOOCCH = CHCOO（ - ），制备式I化合物的方法和制备方法的新中间体。 式I的化合物具有杀线虫和杀真菌性质。 描述了含有至少一种式I化合物作为活性成分的杀线虫和杀真菌组合物，以及使用化合物和组合物控制线虫和真菌的方法。

公开(公告)号：US4947002A

公开(公告)日：1990-08-07

申请号：US266036

申请日：1988-11-02

申请人： Georg Frater ,  Urs Muller

发明人： Georg Frater ,  Urs Muller

IPC分类号： A61K8/35 ,  A61L9/01 ,  A61Q13/00 ,  C07C27/00 ,  C07C29/56 ,  C07C35/37 ,  C07C45/00 ,  C07C49/417 ,  C07C49/453 ,  C07C67/00 ,  C07C69/00 ,  C07C69/08 ,  C07C69/16 ,  C11B9/00

CPC分类号： C07C69/00 ,  C07C35/37 ,  C07C49/453 ,  C11B9/0042 ,  C07C2103/00

摘要： Novel compounds of the formula ##STR1## wherein: the symbols R.sup.1, R.sup.2, R.sup.4, R.sup.5 and R.sup.6 represent hydrogen or methyl, with the proviso that only one of R.sup.1, R.sup.2 and R.sup.4 represents methyl, and, when either or both R.sup.5 and R.sup.6 represent methyl, then R.sup.1, R.sup.2 and R.sup.4 represent hydrogen; and,either the symbol (.dbd.O) on the carbon designated by the number 1 or the symbol (.dbd.O) on the carbon designated by the number 3, represents a keto group, such that when the group is present on carbon 1, then carbon 3 may contain a methyl group.and their use as odorants are described.

摘要翻译： 新颖的下式化合物其中：符号R1，R2，R4，R5和R6表示氢或甲基，条件是R1，R2和R4中只有一个表示甲基，当R5和 R6表示甲基，则R1，R2和R4表示氢; 并且由数字1表示的碳上的符号（= O）或由数字3表示的碳上的符号（= O）表示酮基，使得当基团存在于碳1上时，则 碳3可以含有甲基。 并描述它们作为气味剂的用途。

公开(公告)号：US4803268A

公开(公告)日：1989-02-07

申请号：US008445

申请日：1987-01-29

申请人： Hans-Georg Brunner ,  Urs Muller

发明人： Hans-Georg Brunner ,  Urs Muller

IPC分类号： A01N37/42 ,  C07C51/00 ,  C07C51/347 ,  C07C62/00 ,  C07C62/38 ,  C07C67/00 ,  C07C67/22 ,  C07C69/757 ,  C07C201/00 ,  C07C205/43 ,  C07C231/00 ,  C07C231/12 ,  C07C233/12 ,  C07C235/82 ,  C07C253/00 ,  C07C255/55 ,  C07C255/60 ,  C07C313/00 ,  C07C323/12 ,  C07C323/40 ,  C07D295/18 ,  C07D295/185 ,  C07D279/10

CPC分类号： C07D295/185 ,  C07C323/00 ,  C07C51/347

摘要： The present invention relates to a novel, optimized process for the preparation of cyclohexanedionecarboxylic acid derivatives of formula I which can be carried out in a single vessel affording a very good yield, which process comprises heating a reactive carboxylic acid derivative of formula III ##STR1## wherein X is a halide, an alkylsulfonic or arylsulfonic acid radical or the molecular radical ##STR2## which is necessary to form an anhydride and R.sub.1 is alkyl or cycloalkyl, with an alkali metal cyanide or copper cyanide, in an inert organic solvent, to give a mixture, then adding in succession to said mixture, at a temperature in the range from 0.degree. C. to room temperature, zinc chloride, an equimolar amount, with respect to the carboxylic acid derivative of formula III, of a 3,5-cyclohexanedione-1-carboxylic acid derivative of formula II ##STR3## wherein A is an ester or amide radical, and, dropwise, an amine, and, after acidifying the reaction mixture with an aqueous acid, isolating the resultant 4-acyl-3,5-cyclohexanedione-1-carboxylic acid derivative of formula I ##STR4## by extraction. Said cyclohexanedionecarboxylic acid derivatives have herbicidal and plant growth regulating properties.

摘要翻译： 本发明涉及一种用于制备式I的环己二酸羧酸衍生物的新型优化方法，其可以在单一容器中进行，提供非常好的产率，该方法包括加热式III的反应性羧酸衍生物 （III）其中X是卤化物，烷基磺酸或芳基磺酸基团或在惰性有机溶剂中与碱金属氰化物或氰化铜形成酸酐而R1是烷基或环烷基所必需的分子基团 ，得到混合物，然后在0℃至室温的温度下连续加入所述混合物，相对于式III的羧酸衍生物，等摩尔量的氯化锌为3 （II）的5-环己二酮-1-羧酸衍生物其中A是酯或酰胺基，并逐滴加入胺，并且在用酸水溶液酸化反应混合物后， 通过萃取分离得到式I的所得4-酰基-3,5-环己二酮-1-羧酸衍生物（I）图像+ TR图像。 所述环己二酸羧酸衍生物具有除草和植物生长调节性质。

公开(公告)号：US4758670A

公开(公告)日：1988-07-19

申请号：US567998

申请日：1984-01-04

申请人： Urs Muller ,  Hermann Rempfler ,  Hans Tobler

发明人： Urs Muller ,  Hermann Rempfler ,  Hans Tobler

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D405/06 ,  C07D521/00 ,  A01N43/64

CPC分类号： C07D231/12 ,  A01N43/50 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： Fluoroazolylpropane derivatives of the formula I ##STR1## are described, in which Az is imidazolyl or triazolyl, R.sup.1 is hydrogen, alkyl or aralkyl which is unsubstituted or substituted by halogen, alkyl, alkoxy, halogenoalkyl, nitro, cyano, carboxyl or alkoxycarbonyl, R.sup.2 is C.sub.1 -C.sub.10 -alkyl which is unsubstituted or substituted by alkoxy, aralkoxy or phenyl, it being possible for the aromatic nuclei of aralkoxy and phenyl in turn to be unsubstituted or substituted by halogen, alkyl, alkoxy, halogenoalkyl, cyano, carboxyl or alkoxycarbonyl, R.sup.3 is hydrogen, alkyl, alkylcarbonyl or aralkyl which is unsubstituted or substituted by halogen, alkoxy, alkyl, halogenoalkyl, cyano, carboxyl or alkoxycarbonyl, R.sup.5 is an unsubstituted or monosubstituted or polysubstituted radical selected from the series comprising C.sub.1 -C.sub.8 -alkyl, C.sub.3 -C.sub.8 -cycloalkyl, C.sub.3 -C.sub.6 -alkenyl, C.sub.3 -C.sub.6 -alkynyl, phenyl, naphthyl, biphenyl, benzylphenyl, benzyloxyphenyl, phenoxyphenyl and aralkyl, and X is oxygen or sulfur; including the acid addition salts, quaternary azolium salts and metal complexes.Methods of preparing these products are also disclosed, as are agrochemical compositions containing one of these compounds as the active substance. A process for controlling phytopathogenic microorganisms and/or for regulating plant growth by means of these substances is also described.

摘要翻译： 描述了式I的氟唑基丙烷衍生物，其中Az是咪唑基或三唑基，R1是氢，未被取代或被卤素，烷基，烷氧基，卤代烷基，硝基，氰基，羧基或烷氧基羰基取代的烷基或芳烷基，R2 是未被取代或被烷氧基，芳烷氧基或苯基取代的C 1 -C 10 - 烷基，芳烷氧基和苯基的芳族核可能是未被取代的或被卤素，烷基，烷氧基，卤代烷基，氰基，羧基或烷氧基羰基 R 3是未取代的或被卤素，烷氧基，烷基，卤代烷基，氰基，羧基或烷氧基羰基取代的烷基，烷基，烷基羰基或芳烷基，R 5是未取代的或单取代的或多取代的基团，其选自包括C 1 -C 8烷基， C 3 -C 8 - 环烷基，C 3 -C 6 - 烯基，C 3 -C 6炔基，苯基，萘基，联苯基，苄基苯基，苄氧基苯基，苯氧基苯基和芳烷基，X是氧或硫; 包括酸加成盐，季铵盐和金属络合物。 还公开了制备这些产物的方法，以及含有这些化合物之一作为活性物质的农药组合物。 还描述了通过这些物质控制植物病原微生物和/或调节植物生长的方法。