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28 条记录 (耗时 0.072 秒)

    Mastitis detection
    22.
    发明申请
    Mastitis detection 有权
    乳腺炎检测

    公开(公告)号：US20050123948A1

    公开(公告)日：2005-06-09

    申请号：US10920408

    申请日：2004-08-18

    申请人： Rodney Claycomb ,  David Whyte

    发明人： Rodney Claycomb ,  David Whyte

    IPC分类号： A01J5/013 ,  A61M31/00 ,  C12M1/34 ,  C12Q1/68

    CPC分类号： A01J5/0131

    摘要： Method and apparatus for testing a milk for mastitis wherein the milk sample is admixed with a detergent under condition that increase the viscosity of the milk sample; the increased viscosity mixture is subjected to a further procedure for further increasing its viscosity; and the further increased viscosity mixture is then tested for an attribute of somatic cells, such as DNA. This determination is then used to establish if the cow from whom the milk came has mastitis.

    摘要翻译： 用于测试用于乳腺炎的乳的方法和装置，其中在增加所述牛奶样品的粘度的条件下将所述牛奶样品与洗涤剂混合; 将增加的粘度混合物进一步进一步提高其粘度的方法; 然后测试进一步增加的粘度混合物的体细胞如DNA的属性。 然后用这个确定来确定牛奶来自哪里的奶牛有乳腺炎。

    Nucleic acids encoding PAK5 polypeptidesm and methods of use thereof
    23.
    发明申请
    Nucleic acids encoding PAK5 polypeptidesm and methods of use thereof 审中-公开
    编码PAK5多肽的核酸及其使用方法

    公开(公告)号：US20070072261A1

    公开(公告)日：2007-03-29

    申请号：US10725330

    申请日：2003-12-02

    申请人： Gregory Plowman ,  Ricardo Martinez ,  David Whyte

    发明人： Gregory Plowman ,  Ricardo Martinez ,  David Whyte

    IPC分类号： C12P21/06 ,  C12N9/12 ,  C07H21/04

    CPC分类号： C12N9/1205 ,  A61K38/00

    摘要： The present invention relates to the nucleic acid molecules encoding an STE20-related family of novel protein kinases, ZC1, ZC2, ZC3, ZC4, STLK2, STLK3, STLK4, STLK5, STLK6, STLK7, KHS2, SULU1, SULU3, GEK2, PAK4 and PAK5, segments and domains thereof, as well as various methods useful for the diagnosis and treatment of various kinase-related diseases and conditions. Mammalian nucleic acid molecules encoding these kinases are particularly disclosed, and more specifically human sources of these nucleic acids are disclosed.

    摘要翻译： 本发明涉及编码STE20相关家族新型蛋白激酶ZC1，ZC2，ZC3，ZC4，STLK2，STLK3，STLK4，STLK5，STLK6，STLK7，KHS2，SULU1，SULU3，GEK2，PAK4的核酸分子和 PAK5，其片段和结构域，以及可用于诊断和治疗各种激酶相关疾病和病症的各种方法。 特别公开了编码这些激酶的哺乳动物核酸分子，更具体地公开了这些核酸的人源。

    Mammalian protein phosphatases
    27.
    发明申请
    Mammalian protein phosphatases 审中-公开
    哺乳动物蛋白磷酸酶

    公开(公告)号：US20050054070A1

    公开(公告)日：2005-03-10

    申请号：US10716442

    申请日：2003-11-20

    申请人： Gregory Plowman ,  David Whyte ,  Gerard Manning

    发明人： Gregory Plowman ,  David Whyte ,  Gerard Manning

    IPC分类号： A61K38/00 ,  C12N9/16 ,  C07H21/04

    CPC分类号： C12N9/16 ,  A61K38/00

    摘要： The present invention relates to phosphatase polypeptides, nucleotide sequences encoding the phosphatase polypeptides, as well as various products and methods useful for the diagnosis and treatment of various phosphatase-related diseases and conditions. Through the use of a bioinformatics strategy, mammalian members of the MAP kinase phosphatase PTP's and STP's have been identified and their protein structure predicted.

    摘要翻译： 本发明涉及磷酸酶多肽，编码磷酸酶多肽的核苷酸序列，以及可用于诊断和治疗各种磷酸酶相关疾病和病症的各种产品和方法。 通过使用生物信息学策略，已经鉴定了MAP激酶磷酸酶PTP和STP的哺乳动物成员，并预测了其蛋白质结构。

    RAS converting endoprotease (RCE) and methods
    28.
    发明授权
    RAS converting endoprotease (RCE) and methods 失效
    RAS转化内皮蛋白酶（RCE）和方法

    公开(公告)号：US06261793B1

    公开(公告)日：2001-07-17

    申请号：US09262749

    申请日：1999-03-04

    申请人： David Whyte ,  Marnie McGuirk ,  Irma Nuñez-Oliva ,  Tish Hockenberry ,  James Pai

    发明人： David Whyte ,  Marnie McGuirk ,  Irma Nuñez-Oliva ,  Tish Hockenberry ,  James Pai

    IPC分类号： C12Q148

    CPC分类号： C12N9/6421 ,  C12Q1/37 ,  G01N2500/00

    摘要： The present invention provides human ras converting endoprotease (RCE), the encoding nucleic acids, recombinant vectors, transformed host cells and methods of making human RCE. More particularly, the invention provides methods of using human RCE in screening systems to identify inhibitors of human RCE useful for the treatment of various medical conditions. This invention further relates to inhibitors of human RCE.

    摘要翻译： 本发明提供人ras转化内蛋白酶（RCE），编码核酸，重组载体，转化的宿主细胞和制备人RCE的方法。 更具体地，本发明提供了使用人RCE在筛选系统中鉴定可用于治疗各种医学病症的人RCE抑制剂的方法。 本发明还涉及人类RCE的抑制剂。