-
21.发明授权Quinoline and isoquinoline derivatives, a process for their production and their use as inflammation inhibitors 有权喹啉和异喹啉衍生物，其制备方法及其作为炎症抑制剂的用途公开(公告)号：US07329753B2
公开(公告)日：2008-02-12
申请号：US11451508
申请日：2006-06-13
申请人： Stefan Jaroch , Manfred Lehmann , Norbert Schmees , Markus Berger , Hartmut Rehwinkel , Konrad Krolikiewicz , Werner Skuballa , Heike Schaecke , Arndt J. G. Schottelius
发明人： Stefan Jaroch , Manfred Lehmann , Norbert Schmees , Markus Berger , Hartmut Rehwinkel , Konrad Krolikiewicz , Werner Skuballa , Heike Schaecke , Arndt J. G. Schottelius
IPC分类号： C07D215/40 , C07D217/24
CPC分类号： A61K31/47 , C07D215/40 , C07D217/24 , C07D405/12
摘要： The invention relates to quinoline and isoquinoline derivatives of general formula I and a process for their production, and their use as inflammation inhibitors.
摘要翻译： 本发明涉及通式I的喹啉和异喹啉衍生物及其生产方法及其作为炎症抑制剂的用途。
-
22.发明申请公开(公告)号：US20050272823A1
公开(公告)日：2005-12-08
申请号：US10960754
申请日：2004-10-08
申请人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
发明人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
IPC分类号： A61K31/135 , C07D209/34 , C07D209/46 , C07D215/38 , C07D217/24 , C07D231/56 , C07D237/30 , C07D239/74 , C07D277/62
CPC分类号： C07D209/34 , C07D209/46 , C07D215/38 , C07D217/24 , C07D231/56 , C07D237/30 , C07D239/74 , C07D277/62
摘要： The invention relates to multiply-substituted tetrahydronaphthalene derivatives of formula (I) process for their production and their use as antiinflammatory agents.
摘要翻译： 本发明涉及式（I）的多取代四氢萘衍生物的制备方法及其作为抗炎剂的用途。
-
23.发明申请公开(公告)号：US20050171109A1
公开(公告)日：2005-08-04
申请号：US10962169
申请日：2004-10-12
申请人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
发明人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
IPC分类号： C07D209/34 , C07D209/46 , C07D215/38 , C07D217/24 , C07D231/56 , C07D237/30 , C07D239/74 , C07D277/62 , C07D471/02 , A61K31/135 , A61K31/405 , A61K31/428 , A61K31/47 , A61K31/498 , A61K31/502
CPC分类号： C07D277/62 , C07D209/34 , C07D209/46 , C07D215/38 , C07D217/24 , C07D231/56 , C07D237/30 , C07D239/74
摘要： The invention relates to tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents.
-
24.发明申请Heterocyclically-substituted pentanol derivatives, process for their production and their use as anti-inflammatory agents 审中-公开杂环取代的戊醇衍生物，其制备方法及其作为抗炎剂的用途公开(公告)号：US20050090559A1
公开(公告)日：2005-04-28
申请号：US10882103
申请日：2004-07-01
申请人： Markus Berger , Stefan Baeurle , Hartmut Rehwinkel , Norbert Schmees , Heike Schaecke , Manfred Lehmann , Konrad Krolikiewicz , Arndt Schottelius , Duy Nguyen , Anne Mengel , Stefan Jaroch
发明人： Markus Berger , Stefan Baeurle , Hartmut Rehwinkel , Norbert Schmees , Heike Schaecke , Manfred Lehmann , Konrad Krolikiewicz , Arndt Schottelius , Duy Nguyen , Anne Mengel , Stefan Jaroch
IPC分类号： C07D209/08 , C07D209/34 , C07D209/46 , C07D231/56 , C07D235/06 , C07D237/28 , C07D237/30 , C07D239/74 , C07D241/42 , C07D277/64 , C07D471/04 , A61K31/495 , A61K31/135 , A61K31/275
CPC分类号： C07D241/42 , C07D209/08 , C07D209/34 , C07D209/46 , C07D231/56 , C07D235/06 , C07D237/28 , C07D237/30 , C07D239/74 , C07D277/64 , C07D471/04
摘要： The invention relates to pentanol derivatives of general formula I that are substituted by quinazoline, quinoxaline, cinnoline, indazole, phthalazine, naphthyridine, benzothiazole, dihydroindolone, dihydroisoindolone, benzimidazole or indole, a process for their production and their use as anti-inflammatory agents.
摘要翻译： 本发明涉及被喹唑啉，喹喔啉，噌啉，吲唑，酞嗪，萘啶，苯并噻唑，二氢吲哚酮，二氢异吲哚酮，苯并咪唑或吲哚取代的通式I的戊醇衍生物，其制备方法及其用作抗炎剂。
-
25.发明授权公开(公告)号：US07662821B2
公开(公告)日：2010-02-16
申请号：US10962169
申请日：2004-10-12
申请人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
发明人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
IPC分类号： A61K31/497 , A61K31/44 , A61K31/415 , A61K31/275 , C07D239/72 , C07D237/26 , C07D209/04 , C07C255/49 , C07C62/38 , C07C211/44
CPC分类号： C07D277/62 , C07D209/34 , C07D209/46 , C07D215/38 , C07D217/24 , C07D231/56 , C07D237/30 , C07D239/74
摘要： The invention relates to tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents.
摘要翻译： 本发明涉及四氢萘衍生物，其制备方法及其作为抗炎剂的用途。
-
26.发明授权公开(公告)号：US07659297B2
公开(公告)日：2010-02-09
申请号：US10960754
申请日：2004-10-08
申请人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
发明人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
IPC分类号： A01N43/56 , C07D231/02 , C07D231/54 , C07D487/00
CPC分类号： C07D209/34 , C07D209/46 , C07D215/38 , C07D217/24 , C07D231/56 , C07D237/30 , C07D239/74 , C07D277/62
摘要： The invention relates to multiply-substituted tetrahydronaphthalene derivatives of formula (I) process for their production and their use as antiinflammatory agents.
摘要翻译： 本发明涉及式（I）的多取代四氢萘衍生物的制备方法及其作为抗炎剂的用途。
-
27.发明申请Quinoline and isoquinoline derivatives, a process for their production and their use as inflammation inhibitors 有权喹啉和异喹啉衍生物，其制备方法及其作为炎症抑制剂的用途公开(公告)号：US20060229333A1
公开(公告)日：2006-10-12
申请号：US11451508
申请日：2006-06-13
申请人： Stefan Jaroch , Manfred Lehmann , Norbert Schmees , Markus Berger , Hartmut Rehwinkel , Konrad Krolikiewicz , Werner Skuballa , Heike Schaecke , Arndt. Schottelius
发明人： Stefan Jaroch , Manfred Lehmann , Norbert Schmees , Markus Berger , Hartmut Rehwinkel , Konrad Krolikiewicz , Werner Skuballa , Heike Schaecke , Arndt. Schottelius
IPC分类号： A61K31/4706 , C07D215/38
CPC分类号： A61K31/47 , C07D215/40 , C07D217/24 , C07D405/12
摘要： The invention relates to quinoline and isoquinoline derivatives of general formula I and a process for their production, and their use as inflammation inhibitors.
摘要翻译： 本发明涉及通式I的喹啉和异喹啉衍生物及其生产方法及其作为炎症抑制剂的用途。
-
28.发明申请Alkylidene-tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents 审中-公开亚烷基 - 四氢萘衍生物，其制备方法及其作为抗炎剂的用途公开(公告)号：US20060084652A1
公开(公告)日：2006-04-20
申请号：US11222250
申请日：2005-09-09
申请人： Stefan Baeurle , Markus Berger , Stefan Jaroch , Konrad Krolikiewicz , Duy Nguyen , Hartmut Rehwinkel , Heike Schaecke , Norbert Schmees , Werner Skuballa
发明人： Stefan Baeurle , Markus Berger , Stefan Jaroch , Konrad Krolikiewicz , Duy Nguyen , Hartmut Rehwinkel , Heike Schaecke , Norbert Schmees , Werner Skuballa
IPC分类号： A61K31/517 , A61K31/502 , A61K31/4704
CPC分类号： C07D247/00
摘要： The invention relates to alkylidene-tetrahydronaphthalene derivatives of general formula (I), process for their production, and their use as anti-inflammatory agents.
摘要翻译： 本发明涉及通式（I）的亚烷基 - 四氢萘衍生物，其制备方法及其作为抗炎剂的用途。
-
公开(公告)号：US20080214641A1
公开(公告)日：2008-09-04
申请号：US12005066
申请日：2007-12-20
申请人： Markus Berger , Jan Dahmen , Karl Edman , Anders Eriksson , Balint Gabos , Thomas Hansson , Martin Hemmerling , Krister Henriksson , Svetlana Ivanova , Matti Lepisto , Darren McKerrecher , Magnus Munck af Rosenschold , Stinabritt Nilsson , Hartmut Rehwinkel , Camilla Taflin
发明人： Markus Berger , Jan Dahmen , Karl Edman , Anders Eriksson , Balint Gabos , Thomas Hansson , Martin Hemmerling , Krister Henriksson , Svetlana Ivanova , Matti Lepisto , Darren McKerrecher , Magnus Munck af Rosenschold , Stinabritt Nilsson , Hartmut Rehwinkel , Camilla Taflin
IPC分类号： A61K31/416 , C07D231/56 , A61P29/00
CPC分类号： C07D231/56 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
摘要： Compounds of formula (I): The present invention relates to novel indazolyl ester or amide derivatives, to pharmaceutical compositions comprising such derivatives, to processes for preparing such novel derivatives and to the use of such derivatives as medicaments
摘要翻译： 式（I）化合物：本发明涉及新的吲唑基酯或酰胺衍生物，包含这些衍生物的药物组合物，制备这种新衍生物的方法以及使用这些衍生物作为药物
-
公开(公告)号：US20080207721A1
公开(公告)日：2008-08-28
申请号：US11986555
申请日：2007-11-21
申请人： Markus Berger , Lena Bergstrom , Jan Dahmen , Anders Eriksson , Balint Gabos , Martin Hemmerling , Krister Henriksson , Svetlana Ivanova , Matti Lepisto , Stinabritt Nilsson , Camilla Taflin , Darren McKerrecher , Hartmut Rehwinkel
发明人： Markus Berger , Lena Bergstrom , Jan Dahmen , Anders Eriksson , Balint Gabos , Martin Hemmerling , Krister Henriksson , Svetlana Ivanova , Matti Lepisto , Stinabritt Nilsson , Camilla Taflin , Darren McKerrecher , Hartmut Rehwinkel
IPC分类号： A61K31/416 , C07D231/56
CPC分类号： C07D231/56 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D413/12
摘要： Compounds of formula (I): or a pharmaceutically acceptable salt thereof, compositions comprising them, processes for preparing them and their use in medical therapy (for example modulating the glucocorticoid receptor in a warm blooded animal).
摘要翻译： 式（I）化合物或其药学上可接受的盐，包含它们的组合物，其制备方法及其在药物治疗中的用途（例如调节温血动物中的糖皮质激素受体）。
-
-
-
-
-
-
-
-
-
搜索结果
82 条记录 (耗时 0.05 秒)
