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公开(公告)号:US20120302617A1
公开(公告)日:2012-11-29
申请号:US13490204
申请日:2012-06-06
申请人: Markus Berger , Hartmut Rehwinkel , Jan Dahmen , Anders Eriksson , Thomas Hansson , Nafizal Hossain , Per Tomas Klingstedt , Matti Lepistö , Stinabritt Nilsson , Martin Hemmerling , Karl Edman
发明人: Markus Berger , Hartmut Rehwinkel , Jan Dahmen , Anders Eriksson , Thomas Hansson , Nafizal Hossain , Per Tomas Klingstedt , Matti Lepistö , Stinabritt Nilsson , Martin Hemmerling , Karl Edman
IPC分类号: C07D405/14 , A61P11/02 , A61P11/00 , A61P11/06 , A61K31/416 , A61P29/00
CPC分类号: C07D409/14 , A61K31/416 , A61K31/4439 , A61K45/06 , C07D231/56 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/10 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/12 , C07D413/12
摘要: A compound of formula Ia: The present invention relates to novel indazolyl derivatives, to pharmaceutical compositions comprising such derivatives, to processes for preparing such novel derivatives and to the use of such derivatives as medicaments.
摘要翻译: 式Ia化合物:本发明涉及新的吲唑基衍生物,包含该衍生物的药物组合物,制备这种新型衍生物的方法以及使用这些衍生物作为药物。
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公开(公告)号:US08211930B2
公开(公告)日:2012-07-03
申请号:US12468561
申请日:2009-05-19
申请人: Markus Berger , Hartmut Rehwinkel , Jan Dahmén , Anders Eriksson , Thomas Hansson , Nafizal Hossain , Per Tomas Klingstedt , Matti Lepistö , Stinabritt Nilsson , Martin Hemmerling , Karl Edman
发明人: Markus Berger , Hartmut Rehwinkel , Jan Dahmén , Anders Eriksson , Thomas Hansson , Nafizal Hossain , Per Tomas Klingstedt , Matti Lepistö , Stinabritt Nilsson , Martin Hemmerling , Karl Edman
IPC分类号: A61K31/416 , C07D231/54
CPC分类号: C07D409/14 , A61K31/416 , A61K31/4439 , A61K45/06 , C07D231/56 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/10 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/12 , C07D413/12
摘要: A compound of formula Ia: The present invention relates to novel indazolyl derivatives, to pharmaceutical compositions comprising such derivatives, to processes for preparing such novel derivatives and to the use of such derivatives as medicaments
摘要翻译: 式Ia化合物:本发明涉及新的吲唑基衍生物,包含该衍生物的药物组合物,制备这种新型衍生物的方法以及使用这些衍生物作为药物。
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公开(公告)号:US20100197644A1
公开(公告)日:2010-08-05
申请号:US12643504
申请日:2009-12-21
申请人: Markus Berger , Jan Dahmén , Karl Edman , Anders Eriksson , Balint Gabos , Thomas Hansson , Martin Hemmerling , Krister Henriksson , Svetlana Ivanova , Matti Lepistö , Darren McKerrecher , Magnus Munck af Rosenschöld , Stinabritt Nilsson , Hartmut Rehwinkel , Camilla Taflin
发明人: Markus Berger , Jan Dahmén , Karl Edman , Anders Eriksson , Balint Gabos , Thomas Hansson , Martin Hemmerling , Krister Henriksson , Svetlana Ivanova , Matti Lepistö , Darren McKerrecher , Magnus Munck af Rosenschöld , Stinabritt Nilsson , Hartmut Rehwinkel , Camilla Taflin
IPC分类号: A61K31/56 , A61K31/5377 , A61K31/501 , A61K31/506 , A61K31/4709 , A61K31/4439 , A61K31/4245 , A61K31/427 , A61K31/428 , A61K31/422 , A61K31/4196 , A61K31/4184 , A61K31/4178 , A61K31/416 , C07D413/10 , C07D403/04 , C07D403/12 , C07D215/12 , C07D401/12 , C07D271/02 , C07D417/12 , C07D277/587 , C07D263/38 , C07D263/40 , C07D249/12 , C07D235/26 , C07D233/90 , C07D231/56 , A61P29/00 , A61P11/06
CPC分类号: C07D231/56 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
摘要: Compounds of formula (I): The present invention relates to novel indazolyl ester or amide derivatives, to pharmaceutical compositions comprising such derivatives, to processes for preparing such novel derivatives and to the use of such derivatives as medicaments
摘要翻译: 式(I)化合物:本发明涉及新的吲唑基酯或酰胺衍生物,包含这些衍生物的药物组合物,制备这种新衍生物的方法以及使用这些衍生物作为药物
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公开(公告)号:US20100087489A1
公开(公告)日:2010-04-08
申请号:US12468561
申请日:2009-05-19
申请人: Markus Berger , Hartmut Rehwinkel , Jan Dahmén , Anders Eriksson , Thomas Hansson , Nafizal Hossain , Per Tomas Klingstedt , Matti Lepistö , Stinabritt Nilsson , Martin Hemmerling , Karl Edman
发明人: Markus Berger , Hartmut Rehwinkel , Jan Dahmén , Anders Eriksson , Thomas Hansson , Nafizal Hossain , Per Tomas Klingstedt , Matti Lepistö , Stinabritt Nilsson , Martin Hemmerling , Karl Edman
IPC分类号: A61K31/4439 , C07D231/56 , C07D401/14 , A61K31/416 , A61P29/00
CPC分类号: C07D409/14 , A61K31/416 , A61K31/4439 , A61K45/06 , C07D231/56 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/10 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/12 , C07D413/12
摘要: A compound of formula Ia: The present invention relates to novel indazolyl derivatives, to pharmaceutical compositions comprising such derivatives, to processes for preparing such novel derivatives and to the use of such derivatives as medicaments
摘要翻译: 式Ia化合物:本发明涉及新的吲唑基衍生物,包含该衍生物的药物组合物,制备这种新型衍生物的方法以及使用这些衍生物作为药物。
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公开(公告)号:US20050136704A1
公开(公告)日:2005-06-23
申请号:US11032846
申请日:2005-01-10
申请人: Seang Malathong , Martin Hemmerling
发明人: Seang Malathong , Martin Hemmerling
CPC分类号: G01R1/0466
摘要: A die carrier is disclosed which is specifically designed for use in a TSOP socket. More specifically, the die carrier has a carrier substrate with carrier contacts thereon that are dimensioned specifically to match the positioning of the upper and lower socket contacts. The carrier substrate, being 145 microns thick, can also fit between the upper and lower socket contacts. A carrier base support component is located below a portion only of the carrier substrate, and does not impair insertion of the carrier substrate into the relatively small spacing between the upper and lower socket contacts. Damage to the carrier substrate is avoided by clamping edges of the carrier substrate from opposing sides between the upper and lower socket contacts. There are no screws or nuts within the carrier base support component that may increase its size and prevent it from being inserted into the socket. A double-sided, robust electrical connection is made by each respective pair of upper and lower socket contacts.
摘要翻译: 公开了专门设计用于TSOP插座的模具载体。 更具体地,模具载体具有其上具有载体接触的载体基板,其尺寸特别地匹配上部和下部插座触头的定位。 145μm厚的载体衬底也可以装配在上和下插座触点之间。 载体基部支撑部件位于仅载体基板的一部分的下方,并且不会妨碍载体基板在上部和下部插座触点之间相对小的间隔中的插入。 通过将载体基板的边缘从上部和下部插座触头之间的相对侧夹紧来避免对载体基板的损坏。 载体基座支撑部件内没有螺丝或螺母,可能会增加其尺寸并防止其插入插座。 双面,坚固的电气连接由每对相应的上,下插座触点组成。
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公开(公告)号:US08143290B2
公开(公告)日:2012-03-27
申请号:US12959027
申请日:2010-12-02
申请人: Markus Berger , Jan Dahmén , Karl Edman , Anders Eriksson , Balint Gabos , Thomas Hansson , Martin Hemmerling , Krister Henriksson , Svetlana Ivanova , Matti Lepistö , Darren McKerrecher , Magnus Munck af Rosenschöld , Stinabritt Nilsson , Hartmut Rehwinkel , Camilla Taflin
发明人: Markus Berger , Jan Dahmén , Karl Edman , Anders Eriksson , Balint Gabos , Thomas Hansson , Martin Hemmerling , Krister Henriksson , Svetlana Ivanova , Matti Lepistö , Darren McKerrecher , Magnus Munck af Rosenschöld , Stinabritt Nilsson , Hartmut Rehwinkel , Camilla Taflin
IPC分类号: A61K31/4427 , C07D401/02
CPC分类号: C07D231/56 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
摘要: Compounds of formula (I): The present invention relates to novel indazolyl ester or amide derivatives, to pharmaceutical compositions comprising such derivatives, to processes for preparing such novel derivatives and to the use of such derivatives as medicaments.
摘要翻译: 式(I)化合物:本发明涉及新的吲唑基酯或酰胺衍生物,包含这些衍生物的药物组合物,制备这种新型衍生物的方法以及使用这些衍生物作为药物。
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公开(公告)号:US20080214641A1
公开(公告)日:2008-09-04
申请号:US12005066
申请日:2007-12-20
申请人: Markus Berger , Jan Dahmen , Karl Edman , Anders Eriksson , Balint Gabos , Thomas Hansson , Martin Hemmerling , Krister Henriksson , Svetlana Ivanova , Matti Lepisto , Darren McKerrecher , Magnus Munck af Rosenschold , Stinabritt Nilsson , Hartmut Rehwinkel , Camilla Taflin
发明人: Markus Berger , Jan Dahmen , Karl Edman , Anders Eriksson , Balint Gabos , Thomas Hansson , Martin Hemmerling , Krister Henriksson , Svetlana Ivanova , Matti Lepisto , Darren McKerrecher , Magnus Munck af Rosenschold , Stinabritt Nilsson , Hartmut Rehwinkel , Camilla Taflin
IPC分类号: A61K31/416 , C07D231/56 , A61P29/00
CPC分类号: C07D231/56 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
摘要: Compounds of formula (I): The present invention relates to novel indazolyl ester or amide derivatives, to pharmaceutical compositions comprising such derivatives, to processes for preparing such novel derivatives and to the use of such derivatives as medicaments
摘要翻译: 式(I)化合物:本发明涉及新的吲唑基酯或酰胺衍生物,包含这些衍生物的药物组合物,制备这种新衍生物的方法以及使用这些衍生物作为药物
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公开(公告)号:US20080167332A1
公开(公告)日:2008-07-10
申请号:US11779700
申请日:2007-07-18
申请人: Scott Gibson , Barry Elkins , Mike Rogers , Ian Hassall , Hong Gu , Zhenyu Wang , Vinod Kumar , Synthana Suresh Kumar , Santosh Kavitake , Sidda Lingesha , Eric Merifield , David Ennis , John Pavey , Austen Pimm , James Reuberson , Bo-Goran Josefsson , Martin Hemmerling , Svetlana Ivanova , Marguerite Mensonides-Harsema , Hakan Schulz , John Mo , Tomas Eriksson , Per Strandberg
发明人: Scott Gibson , Barry Elkins , Mike Rogers , Ian Hassall , Hong Gu , Zhenyu Wang , Vinod Kumar , Synthana Suresh Kumar , Santosh Kavitake , Sidda Lingesha , Eric Merifield , David Ennis , John Pavey , Austen Pimm , James Reuberson , Bo-Goran Josefsson , Martin Hemmerling , Svetlana Ivanova , Marguerite Mensonides-Harsema , Hakan Schulz , John Mo , Tomas Eriksson , Per Strandberg
IPC分类号: A61K31/438 , A61P11/00 , C07D491/107 , C07C275/32 , C07D211/52 , C07C69/76 , C07C69/52 , C07C233/81 , C07C233/00 , C07D303/46 , A61P29/00
CPC分类号: C07C233/25 , C07C69/92 , C07C235/60 , C07D211/48 , C07D303/23 , C07D491/107
摘要: Compounds of formula (I) wherein R1, R3, R4, R5, R6, R7, and R10 are as defined in the specification, are described. The present invention also relates to pharmaceutical composition comprising said compounds and to the use of said compounds in therapy. The present invention further relates to processes for the preparation of said compounds and to new intermediates useful in the preparation thereof. Beside, the invention relates to salts and polymorphic forms of the new compounds as well as the preparation thereof.
摘要翻译: 式(I)的化合物,其中R 1,R 3,R 4,R 5,R SUP > 6 SUP>,R< 7>和< 10>如说明书中所定义。 本发明还涉及包含所述化合物的药物组合物和所述化合物在治疗中的用途。 本发明还涉及制备所述化合物的方法和可用于其制备的新中间体。 除此之外,本发明涉及新化合物的盐和多晶型物及其制备。
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公开(公告)号:US20060287355A1
公开(公告)日:2006-12-21
申请号:US10556228
申请日:2004-05-06
IPC分类号: A61K31/4745 , C07D471/02 , C07D491/02 , C07D498/02
CPC分类号: C07D513/04 , C07D471/04
摘要: The present invention relates to novel imidazo and thiazolopyridine compounds which are kinase inhibitors, methods for their preparation intermediates and pharmaceutical compositions comprising them. Formula (I)
摘要翻译: 本发明涉及作为激酶抑制剂的新型咪唑并噻唑并吡啶化合物,其制备方法及其制备方法。 式(I)
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公开(公告)号:US08916600B2
公开(公告)日:2014-12-23
申请号:US13490204
申请日:2012-06-06
申请人: Markus Berger , Hartmut Rehwinkel , Jan Dahmén , Anders Eriksson , Thomas Hansson , Nafizal Hossain , Per Tomas Klingstedt , Matti Lepistö , Stinabritt Nilsson , Martin Hemmerling , Karl Edman
发明人: Markus Berger , Hartmut Rehwinkel , Jan Dahmén , Anders Eriksson , Thomas Hansson , Nafizal Hossain , Per Tomas Klingstedt , Matti Lepistö , Stinabritt Nilsson , Martin Hemmerling , Karl Edman
IPC分类号: A61K31/416 , C07D231/54 , C07D405/14 , C07D409/12 , C07D231/56 , C07D409/14 , C07D403/12 , C07D401/12 , C07D405/12 , C07D401/14 , C07D403/10 , C07D413/12
CPC分类号: C07D409/14 , A61K31/416 , A61K31/4439 , A61K45/06 , C07D231/56 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/10 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/12 , C07D413/12
摘要: A compound of formula Ia: The present invention relates to novel indazolyl derivatives, to pharmaceutical compositions comprising such derivatives, to processes for preparing such novel derivatives and to the use of such derivatives as medicaments.
摘要翻译: 式Ia化合物:本发明涉及新的吲唑基衍生物,包含该衍生物的药物组合物,制备这种新型衍生物的方法以及使用这些衍生物作为药物。
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