公开(公告)号：US20070075020A1

公开(公告)日：2007-04-05

申请号：US11242210

申请日：2005-10-03

申请人： Mark Kelm ,  Christopher Johnson ,  Rebecca Robbins

发明人： Mark Kelm ,  Christopher Johnson ,  Rebecca Robbins

IPC分类号： B01D15/08

CPC分类号： B01D15/32 ,  B01J20/286 ,  B01J20/288 ,  B01J2220/54

摘要： An improved process for separating and isolating individual polar protic monomer(s) and/or oligomer(s) on the basis of degree of polymerization. A liquid sample containing polar protic monomer(s) and/or oligomer(s) is introduced into a liquid chromatography (LC) column packed with a polar bonded stationary chromatographic phase. The individual polar protic monomer(s) and/or oligomer(s) are separated via a binary mobile phase elution. One or more individual fractions containing the monomer(s) and/or oligomer(s) are eluted. The polar protic monomer(s) and/or oligomer(s) may be proanthocyanidins, hydrolyzable tannins, oligosaccharides, oligonucleotides, peptides, acrylamides, polysorbates, polyketides, poloxamers, polyethylene glycols, polyoxyethylene alcohols or polyvinyl alcohols. The binary mobile phase comprises an A phase consisting essentially of a polar aprotic solvent and a B phase consisting essentially of a polar protic solvent. A process for separating and isolating xanthine(s) (e.g., caffeine and theobromine) from polar protic monomer(s) and/or oligomer(s). A liquid sample containing xanthine(s) and polar protic monomer(s) and/or oligomer(s) is introduced into an LC column packed with a polar bonded stationary chromatographic phase. The xanthines are separated via an isocratic mobile phase elution, and one or more individual fractions containing the xanthines are eluted.

摘要翻译： 基于聚合度分离和分离各极性质子单体和/或低聚物的改进方法。 将含有极性质子单体和/或低聚物的液体样品引入填充有极性键合静止色谱相的液相色谱（LC）柱中。 单独的极性质子单体和/或低聚物通过二元流动相洗脱分离。 洗脱含有单体和/或低聚物的一种或多种单独级分。 极性质子单体和/或低聚物可以是原花青素，可水解单宁，寡糖，寡核苷酸，肽，丙烯酰胺，聚山梨酯，聚酮化合物，泊洛沙姆，聚乙二醇，聚氧乙烯醇或聚乙烯醇。 二元流动相包含基本上由极性非质子溶剂和基本上由极性质子溶剂组成的B相组成的A相。 从极性质子单体和/或低聚物分离和分离黄嘌呤（例如咖啡因和可可碱）的方法。 将含有黄嘌呤和极性质子单体和/或低聚物的液体样品引入填充有极性键合的静止色谱相的LC柱中。 黄嘌呤通过等度流动相洗脱分离，并且洗脱含有黄嘌呤的一个或多个单独级分。

公开(公告)号：US20060167563A1

公开(公告)日：2006-07-27

申请号：US11338995

申请日：2006-01-25

申请人： Christopher Johnson ,  Aaron Taszreak

发明人： Christopher Johnson ,  Aaron Taszreak

IPC分类号： A61F2/66

CPC分类号： A61F2/66 ,  A61F2/6607 ,  A61F2002/30359 ,  A61F2002/3051 ,  A61F2002/5003 ,  A61F2002/5007 ,  A61F2002/5055 ,  A61F2002/6621 ,  A61F2002/665 ,  A61F2220/0025 ,  A61F2220/0033

摘要： A prosthetic foot includes a sole plate having a body formed of resilient material. The sole plate is elongated along an anterior and posterior axis wherein an anterior portion of the plate defines a toe portion and the posterior portion defines a heel portion. An ankle member having a planar portion in contact with the sole plate is rigidly affixed to the sole plate at the heel portion. The ankle member has an extension portion positioned anterior of the planar portion and separated from the planar portion by a transition portion. A resilient pad is disposed between the contact portion of the ankle member and the sole plate. The resilient pad and extension portion of ankle member define a gap such that as a user's weight is transferred anterior following initial contact, the extension portion of the ankle member tilts forward reducing the gap formed between the resilient pad and the extension portion for improving the dorsiflexion of the prosthetic foot.

摘要翻译： 假脚包括具有由弹性材料形成的主体的底板。 鞋底板沿着前后轴线是细长的，其中板的前部限定脚趾部分，并且后部限定鞋跟部分。 具有与鞋底板接触的平面部分的脚踝构件在脚跟部分处刚性地固定到鞋底板。 踝构件具有位于平面部分前方的延伸部分，并且通过过渡部分与平面部分分离。 弹性垫设置在踝构件的接触部分和底板之间。 踝构件的弹性垫和延伸部限定了间隙，使得当初次接触之后使用者的重量向前移动时，踝构件的延伸部分向前倾斜，减少弹性垫和延伸部之间形成的间隙，以改善背屈 的假脚。

公开(公告)号：US20060111931A1

公开(公告)日：2006-05-25

申请号：US11321828

申请日：2005-12-29

申请人： Christopher Johnson ,  Onur Dulgeroglu ,  Peter Kalish ,  Kunter Akbay

发明人： Christopher Johnson ,  Onur Dulgeroglu ,  Peter Kalish ,  Kunter Akbay

IPC分类号： G06Q99/00 ,  G05B19/418 ,  G06F15/02 ,  G07G1/00

CPC分类号： G06Q10/10 ,  G06Q10/063 ,  G06Q10/067

摘要： A method for using and interacting with mathematical or algorithmic business system transfer functions in support of a business information, analysis, decisioning and control system. The method includes developing at least one high-level business system view wherein the transfer function is configured to quantitatively express the business system view; identifying a number of input parameters associated with one or more of the resources used in the business process, identifying at least one output parameter associated with the operation of the business process; collecting operational data that associate the number of input parameters with the at least one output parameter based on an actual operation of the business process. The method also includes a primary display layer that presents a control scenario for a testbed environment for the business information and decisioning control system.

摘要翻译： 一种使用和与数学或算法业务系统传输功能进行交互的方法，以支持业务信息，分析，决策和控制系统。 该方法包括开发至少一个高级业务系统视图，其中传送功能被配置为定量地表达业务系统视图; 识别与业务过程中使用的一种或多种资源相关联的输入参数的数量，识别与业务过程的操作相关联的至少一个输出参数; 收集基于所述业务过程的实际操作将所述输入参数的数量与所述至少一个输出参数相关联的操作数据。 该方法还包括主显示层，其为业务信息和决策控制系统的测试台环境呈现控制场景。

公开(公告)号：US20060086947A1

公开(公告)日：2006-04-27

申请号：US11254633

申请日：2005-10-20

申请人： Christopher Johnson

发明人： Christopher Johnson

IPC分类号： H01L33/00

CPC分类号： G02B6/4248 ,  G02B6/4202 ,  G02B6/4239 ,  H01L2224/48091 ,  H01S5/02212 ,  H01S5/02284 ,  H01S5/02296 ,  H01S5/0683 ,  H01S5/183 ,  H01L2924/00014

摘要： The present invention relates to affixing components of optical packages. The optical packages can include an optical component, such as a TO-Can. The TO-Can can house an optical transmitter and/or an optical receiver. Another optical component of the optical package can be a barrel for aligning the TO-Can with an optical fiber. The TO-Can can be affixed within an open end of the optical barrel using a bonding substance, such as an epoxy, that has wicking properties. The wicking properties cause the bonding substance to enter a gap between the optical barrel and the TO-Can by capillary action. Use of the bonding substance with wicking properties creates a more robust optical package in a cost effective manner.

公开(公告)号：US20060062056A1

公开(公告)日：2006-03-23

申请号：US11270578

申请日：2005-11-10

申请人： Christopher Johnson ,  Scott Schaefer

发明人： Christopher Johnson ,  Scott Schaefer

IPC分类号： G11C8/00 ,  G11C7/00

CPC分类号： G11C7/225 ,  G11C7/1045 ,  G11C7/22 ,  G11C8/18 ,  G11C2207/2227

摘要： The present invention provides a memory device having a mode register with a selectable bit which sets the memory device to operate with a selected one of a plurality of possible clock input signals, for example, a single clock input or differential clock input.

公开(公告)号：US20060032154A1

公开(公告)日：2006-02-16

申请号：US10918815

申请日：2004-08-13

申请人： Christopher Johnson

发明人： Christopher Johnson

IPC分类号： A47F10/00 ,  E04H6/00

CPC分类号： E04H9/14 ,  Y02A50/14

摘要： An underground seamless storm shelter for use during severe weather. The storm shelter is comprised of a single piece base formed by a rotational molding process and an impervious, steel plate cover that is secured to the base by a method forming a watertight seal. The cover comprises a steel door that serves as the means of entrance into the shelter. In addition, a ladder is attached to the cover to facilitate entry and exit. The storm shelter has a ventilation system that provides fresh air to the inhabitants. The storm shelter is secured to the ground by a plurality of anchors that are attached to the cover.

摘要翻译： 在恶劣天气下使用的地下无缝防风雨棚。 风雨棚由通过旋转成型工艺形成的单件底座和通过形成水密密封的方法固定到基座的不透水钢板盖组成。 盖子包括一个钢门，用作入口的手段。 此外，梯子附着在盖子上以方便进出。 风雨棚有一个通风系统，为居民提供新鲜空气。 暴风雨棚通过附接到盖的多个锚固定到地面。

公开(公告)号：US20050185904A1

公开(公告)日：2005-08-25

申请号：US11092626

申请日：2005-03-30

申请人： Christopher Johnson ,  Nicholas Nechitailo

发明人： Christopher Johnson ,  Nicholas Nechitailo

IPC分类号： B29D11/00 ,  G02B6/44

CPC分类号： G02B6/448 ,  B29D11/00663

摘要： The present invention introduces a concept of “smart” ribbons, which use functionally tensioned optical fibers during the manufacture of fiber optic ribbons to create fiber ribbons with controlled geometrical configuration, optimized strain distribution and reduced attenuation. The ribbons may have flat or bowed cross section and be straight along the length or curved in its plane, or twisted unidirectionally, or periodically. These shapes and residual stress-strain state are induced and controlled by using tension functions instead of traditional constant-value tension per fiber during the ribbon manufacture. Further, the present invention reduces signal loss and/or attenuation in ribbon fibers caused by an increase in the strain variation from tensile strain to compressive strain along the length of the individual fibers when ribbons are manufactured, stacked, stranded around a strength member or twisted and bent during cable installation. In a first embodiment of the present invention, either a symmetric or non-symmetric load distribution is applied across the fibers being placed or drawn into a ribbon structure to eliminate or control residual twist in a completed fiber ribbon. Additionally, in the present invention, the load distribution on the fibers of a ribbon can be varied (e.g. periodically changed) along the length of the ribbon to provide a ribbon with the required design characteristics for any particular application. In a second embodiment of the invention, a fiber optic ribbon is made up of a plurality of sub-unit ribbons arranged in substantially the same plane. Each sub-unit ribbon includes a plurality of optical fibers coated by sub-unit matrices.

摘要翻译： 本发明引入了“智能”带的概念，其在制造光纤带期间使用功能张紧的光纤以产生具有受控几何构型，优化的应变分布和减小的衰减的光纤带。 带可以具有平坦或弯曲的横截面，并且沿着该长度是直的或在其平面上弯曲，或者单向扭转或周期性地扭曲。 这些形状和残余应力应变状态通过使用张力函数来引导和控制，而不是色带制造期间每个纤维的传统恒定值张力。 此外，本发明减少了当色带被制造，堆叠，绞合在强度构件上或绞合时沿着单个纤维的长度的应变变化从拉伸应变变化到压缩应变的增加引起的带状纤维中的信号损失和/或衰减 并在电缆安装期间弯曲。 在本发明的第一实施例中，将对称或非对称的负载分布施加在放置或拉入带状结构中的纤维上，以消除或控制完成的纤维带中的残余扭曲。 另外，在本发明中，带的纤维上的载荷分布可以沿着带的长度改变（例如周期性地改变），以便为任何特定应用提供具有所需设计特征的带。 在本发明的第二实施例中，光纤带由布置在基本相同的平面中的多个子单元带构成。 每个子单元带包括由子单元矩阵涂覆的多个光纤。

公开(公告)号：US20050176759A1

公开(公告)日：2005-08-11

申请号：US10499776

申请日：2002-12-20

申请人： Mahmood Ahmed ,  Steven Bromidge ,  Ian Forbes ,  Andrew Gribble ,  Christopher Johnson ,  Francis King ,  Andrew Lightfoot ,  Gregor Macdonald ,  Stephen Moss ,  Mervyn Thompson ,  David Witty

发明人： Mahmood Ahmed ,  Steven Bromidge ,  Ian Forbes ,  Andrew Gribble ,  Christopher Johnson ,  Francis King ,  Andrew Lightfoot ,  Gregor Macdonald ,  Stephen Moss ,  Mervyn Thompson ,  David Witty

IPC分类号： C07D223/14 ,  A61K31/55 ,  A61P1/08 ,  A61P3/04 ,  A61P15/00 ,  A61P25/00 ,  A61P25/14 ,  A61P25/16 ,  A61P25/18 ,  A61P25/20 ,  A61P25/22 ,  A61P25/24 ,  A61P25/28 ,  A61P25/30 ,  C07D223/16 ,  C07D401/12 ,  C07D403/12 ,  A61K31/47 ,  A61K31/4035

CPC分类号： C07D223/16 ,  C07D401/12 ,  C07D403/12

摘要： Invented are non-peptide TPO mimetics. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.

摘要翻译： 发明的是非肽TPO模拟物。 还发明了一种在有需要的哺乳动物（包括人）中治疗血小板减少症的方法，其包括向所述哺乳动物施用有效量的选择的羟基-1-偶氮苯衍生物。

公开(公告)号：US20050090485A1

公开(公告)日：2005-04-28

申请号：US10503678

申请日：2003-02-13

申请人： Steven Bromidge ,  Christopher Johnson ,  Stephen Moss ,  Shahzad Rahman ,  David Witty

发明人： Steven Bromidge ,  Christopher Johnson ,  Stephen Moss ,  Shahzad Rahman ,  David Witty

IPC分类号： A61K31/40 ,  A61K31/47 ,  A61K31/55 ,  A61P3/04 ,  A61P25/06 ,  A61P25/08 ,  A61P25/18 ,  A61P25/22 ,  A61P25/24 ,  A61P25/28 ,  A61P25/30 ,  C07D209/44 ,  C07D217/02 ,  C07D217/04 ,  C07D223/16 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  C07D413/12

CPC分类号： C07D223/16 ,  A61K31/40 ,  A61K31/47 ,  A61K31/55 ,  C07D209/44 ,  C07D217/02 ,  C07D217/04 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  C07D413/12

摘要： The present invention relates to novel sulfonamide compounds having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of CNS and other disorders.

摘要翻译： 本发明涉及具有药理学活性的新型磺酰胺化合物，其制备方法，含有它们的组合物及其在治疗CNS和其它疾病中的用途。

公开(公告)号：US20050040614A1

公开(公告)日：2005-02-24

申请号：US10865992

申请日：2004-06-14

申请人： Christopher Johnson ,  Ralph McCann

发明人： Christopher Johnson ,  Ralph McCann

IPC分类号： B62B3/14 ,  B62D39/00

CPC分类号： B62B3/144 ,  B62B3/1476 ,  B62B2207/02 ,  B62B2501/065

摘要： A cart having a frame member with upright and lateral frame portions. A platform is attached to the lateral frame portion and a removable seat assembly is secured to the upright frame portion. The cart includes a coupling mechanism for coupling to an adjacent cart, of a different type, if required. The platform may be pivotally attached to the frame member. The cart may be nestable.

摘要翻译： 一种具有具有直立和侧框架部分的框架构件的推车。 平台附接到侧框架部分，并且可拆卸的座椅组件固定到直立框架部分。 如果需要，推车包括用于联接到相邻推车的联接机构，其具有不同类型。 平台可以枢转地附接到框架构件。 推车可能是可嵌套的。