公开(公告)号：US20190105425A1

公开(公告)日：2019-04-11

申请号：US16155763

申请日：2018-10-09

申请人： MicroVention, Inc.

发明人： Gregory M. Cruise ,  Xinping Wu ,  Matthew J. Fitz ,  Yue Wu

IPC分类号： A61L24/00

摘要： Liquid embolic preparations and medical treatment methods of using those preparations are described. In some embodiments, the preparations or solutions can transition from a liquid to a solid for use in the embolization. The preparations can include biocompatible polymers with covalently bound radioactive iodine isotopes.

公开(公告)号：US10155064B2

公开(公告)日：2018-12-18

申请号：US15878294

申请日：2018-01-23

申请人： MicroVention, Inc.

发明人： Gregory M. Cruise ,  Steve Plotkin ,  Xinping Wu

IPC分类号： C08F220/38 ,  C08F220/56 ,  C08F222/10 ,  C08F222/38 ,  C08F222/40 ,  A61K9/00 ,  A61K9/16 ,  A61L24/06 ,  A61L24/00

摘要： Embolic particles are described. The particles are reaction products of a prepolymer solution including at least one polyether macromer and an appropriate monomer.

公开(公告)号：US09907880B2

公开(公告)日：2018-03-06

申请号：US15081648

申请日：2016-03-25

申请人： MicroVention, Inc.

发明人： Gregory M. Cruise ,  Steve Plotkin ,  Xinping Wu

IPC分类号： C08F222/38 ,  A61L24/06 ,  A61L24/00

CPC分类号： A61L24/06 ,  A61L24/001 ,  A61L2430/36 ,  C08F222/385 ,  C08L33/08 ,  C08L33/10 ,  C08L33/26

摘要： Embolic particles are described comprising a treated polymer particle. The particles are reaction products of a prepolymer solution including at least one polyether macromer and an appropriate monomer. The treated polymer particles can have a first diameter that is smaller than a second diameter, wherein the second diameter is achieved when the treated polymer particle is subjected to a physiological condition. Methods of making and using these polymer particles are also described.

公开(公告)号：US20230330309A1

公开(公告)日：2023-10-19

申请号：US18114088

申请日：2023-02-24

申请人： MicroVention, Inc.

发明人： Aaron Baldwin ,  Xinping Wu ,  Bryan Fiamengo ,  Garrett Ulrich ,  John Belletto

IPC分类号： B05D3/14 ,  A61L31/10 ,  A61L31/02 ,  B05D7/16 ,  A61L33/06

CPC分类号： A61L33/062 ,  A61L31/022 ,  A61L31/10 ,  B05D3/142 ,  B05D7/16 ,  A61L2420/02

摘要： Described are medical devices including expandable tubular bodies configured to be implanted into a lumen, wherein the outer surface of the expandable tubular bodies are coupled to a polymer(s).

公开(公告)号：US20230099559A1

公开(公告)日：2023-03-30

申请号：US17942004

申请日：2022-09-09

申请人： MicroVention, Inc.

发明人： Xinping Wu ,  Jodi Hong ,  Gregory M. Cruise

IPC分类号： A61F2/06 ,  A61L31/14 ,  A61F2/00 ,  A61L31/02 ,  A61L31/10

摘要： Described are medical devices including expandable tubular bodies configured to be implanted into a lumen, wherein the outer surface of the expandable tubular bodies are coupled to a polymer(s).

公开(公告)号：US10576182B2

公开(公告)日：2020-03-03

申请号：US16155763

申请日：2018-10-09

申请人： MicroVention, Inc.

发明人： Gregory M. Cruise ,  Xinping Wu ,  Matthew J. Fitz ,  Yue Wu

IPC分类号： A61L24/00

摘要： Liquid embolic preparations and medical treatment methods of using those preparations are described. In some embodiments, the preparations or solutions can transition from a liquid to a solid for use in the embolization. The preparations can include biocompatible polymers with covalently bound radioactive iodine isotopes.

公开(公告)号：US10543295B2

公开(公告)日：2020-01-28

申请号：US16505326

申请日：2019-07-08

申请人： MicroVention, Inc.

发明人： Gregory M. Cruise ,  Steve Plotkin ,  Xinping Wu

IPC分类号： C08F220/38 ,  C08F220/56 ,  C08F222/10 ,  C08F222/38 ,  C08F222/40 ,  A61K9/00 ,  A61K9/16 ,  A61L24/06 ,  A61L24/00

摘要： Embolic particles are described. The particles are reaction products of a prepolymer solution including at least one polyether macromer and an appropriate monomer.

公开(公告)号：US20180085497A1

公开(公告)日：2018-03-29

申请号：US15719241

申请日：2017-09-28

申请人： MicroVention, Inc.

发明人： Gloria Hincapie ,  Xinping Wu ,  Yue Wu ,  Gregory M. Cruise

IPC分类号： A61L31/04 ,  C08F236/20 ,  A61L31/14

CPC分类号： A61L24/0015 ,  A61B17/12109 ,  A61B17/12113 ,  A61B17/12181 ,  A61B2017/00004 ,  A61K31/4745 ,  A61K31/555 ,  A61K47/6927 ,  A61L24/0042 ,  A61L24/06 ,  A61L26/0014 ,  A61L26/0061 ,  A61L26/009 ,  A61L31/048 ,  A61L31/148 ,  A61L2300/204 ,  A61L2300/224 ,  A61L2400/06 ,  A61L2430/36 ,  C08F220/56 ,  C08F236/20 ,  C08L33/08 ,  C08L33/10 ,  C08L33/12 ,  C08L33/26

摘要： Biodegradable, cross-linked polymer particle embolics and methods of making the same are described. The particle embolics can be used as embolization agents.

公开(公告)号：US20160279282A1

公开(公告)日：2016-09-29

申请号：US15081648

申请日：2016-03-25

申请人： MicroVention, Inc.

发明人： Gregory M. Cruise ,  Steve Plotkin ,  Xinping Wu

IPC分类号： A61L24/06 ,  A61L24/00 ,  C08F222/38

CPC分类号： A61L24/06 ,  A61L24/001 ,  A61L2430/36 ,  C08F222/385 ,  C08L33/08 ,  C08L33/10 ,  C08L33/26

摘要： Embolic particles are described comprising a treated polymer particle. The particles are reaction products of a prepolymer solution including at least one polyether macromer and an appropriate monomer. The treated polymer particles can have a first diameter that is smaller than a second diameter, wherein the second diameter is achieved when the treated polymer particle is subjected to a physiological condition. Methods of making and using these polymer particles are also described.

摘要翻译： 描述包含经处理的聚合物颗粒的栓塞颗粒。 颗粒是包含至少一种聚醚大分子单体和合适单体的预聚物溶液的反应产物。 经处理的聚合物颗粒可以具有小于第二直径的第一直径，其中当经处理的聚合物颗粒经受生理条件时，实现第二直径。 还描述了制备和使用这些聚合物颗粒的方法。