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51 条记录 (耗时 0.033 秒)

    Block copolymer elastomer catheter balloons
    23.
    发明授权
    Block copolymer elastomer catheter balloons 失效

    公开(公告)号：US5830182A

    公开(公告)日：1998-11-03

    申请号：US805899

    申请日：1997-02-25

    申请人： Lixiao Wang ,  Jianhua Chen

    发明人： Lixiao Wang ,  Jianhua Chen

    IPC分类号： A61L29/06 ,  A61L29/14 ,  A61M29/00

    CPC分类号： A61L29/14 ,  A61L29/06 ,  B29L2031/7542

    摘要： Balloons for medical devices, particularly balloon angioplasty catheters, are made from particular block copolymer thermoplastic elastomers in which the block copolymer is made up of hard segments of a polyester or polyamide and soft segments of polyether; the polyester hard segments are polyesters of an aromatic dicarboxylic acid and a C.sub.2 -C.sub.4 diol; the polyamide hard segments are polyamides of C.sub.6 or higher carboxylic acids and C.sub.6 or higher organic diamines or of C.sub.6 or higher aliphatic .omega.-amino-.alpha.-acids, and the polyether soft segments are polyethers of C.sub.2 -C.sub.10, diols; the block copolymer has a low flexural modulus, namely less than 150,000 psi; the block copolymer has a hardness, Shore D scale, of greater than 60; and the percentage by weight of the block polymer attributable to the hard segments is between about 50% and about 95%. The polymers provide high strength, thin wall, compliant and semi-compliant balloons, which leads to a low profile catheter. The low profile catheters have very good initial crossing, good trackability, good recrossing after first inflation.

    Polypeptides for the treatment or prevention of cancer and uses thereof
    24.
    发明授权
    Polypeptides for the treatment or prevention of cancer and uses thereof 有权
    用于治疗或预防癌症的多肽及其用途

    公开(公告)号：US09328141B2

    公开(公告)日：2016-05-03

    申请号：US13639488

    申请日：2010-09-29

    申请人： Jianhua Chen ,  Yi Huang ,  Junyu Xiong ,  Caihong Chen

    发明人： Jianhua Chen ,  Yi Huang ,  Junyu Xiong ,  Caihong Chen

    IPC分类号： C07K7/08 ,  C07K5/00 ,  A61K38/07 ,  A61K38/10 ,  C07K5/103

    CPC分类号： C07K7/08 ,  A61K38/07 ,  A61K38/10 ,  C07K5/00 ,  C07K5/101

    摘要： Disclosed herein are polypeptides or their derivatives and their application. The polypeptides and their derivatives can treat or prevent cancer. The polypeptides of the invention have significant lethality to the cancer cells when used alone. When its clinical commonly used chemotherapy drugs such as cisplatin in combination, it can significantly increase the sensitivity of chemotherapeutic agents on cancer cells, to enhance its lethality of cancer cells, to reduce the dosage. The peptides can kill a variety of cancer cells, but without apparent toxicity enhancing effect on normal cells. The prepared peptides of the present invention can be chemically synthesized, high-purity, low molecular weight, specificity, non-immunogenic, safe and reliable.

    摘要翻译： 本文公开的是多肽或其衍生物及其应用。 多肽及其衍生物可以治疗或预防癌症。 当单独使用时，本发明的多肽对癌细胞具有显着的致死性。 当其临床常用化疗药物如顺铂联合使用时，可显着增加化疗药对癌细胞的敏感性，增强其对癌细胞的致死性，降低剂量。 肽可以杀死各种癌细胞，但对正常细胞没有明显的毒性增强作用。 本发明制备的肽可以化学合成，高纯度，低分子量，特异性，非免疫原性，安全可靠。

    Reflowable Circuit Protection Device
    25.
    发明申请
    Reflowable Circuit Protection Device 有权
    可回流电路保护装置

    公开(公告)号：US20140035716A1

    公开(公告)日：2014-02-06

    申请号：US13567245

    申请日：2012-08-06

    申请人： Shelomon Patrick Doblack ,  Jianhua Chen ,  Matthew P. Galla

    发明人： Shelomon Patrick Doblack ,  Jianhua Chen ,  Matthew P. Galla

    IPC分类号： H01H85/36

    CPC分类号： H01H85/36 ,  H01H37/761 ,  H01H2037/046 ,  H01H2037/762

    摘要： A circuit protection device includes a housing, which includes first and second electrodes. The device includes a conductive slider inside the housing. At a first location within the housing, the slider provides an electrical connection between the first and second electrodes. At a second location within the housing, the slider does not provide the electrical connection. A spring is secured to and stretched between the slider and an inner side of the housing such that the spring is held in tension in an expanded state. The slider is held at the first location by a solder between the slider and the first and second electrodes. After the device is armed, detection of an over-temperature condition causes the solder to begin to melt and the spring to compress and pull the slider to the second location within the housing, thus severing the electrical connection between the first and second electrodes.

    摘要翻译： 电路保护装置包括壳体，其包括第一和第二电极。 该装置包括在壳体内的导电滑块。 在壳体内的第一位置处，滑块提供第一和第二电极之间的电连接。 在壳体内的第二位置处，滑块不提供电连接。 弹簧被固定到滑块和壳体的内侧之间并被拉伸，使得弹簧在膨胀状态下保持张紧。 滑块通过滑块和第一和第二电极之间的焊料保持在第一位置。 在装置布防后，检测到过温度状况导致焊料开始熔化，并且弹簧压缩并拉动滑块到壳体内的第二位置，从而切断第一和第二电极之间的电连接。

    Polypeptides for the Treatment or Prevention of Cancer and uses Thereof
    26.
    发明申请
    Polypeptides for the Treatment or Prevention of Cancer and uses Thereof 审中-公开
    用于治疗或预防癌症的多肽及其用途

    公开(公告)号：US20130149372A1

    公开(公告)日：2013-06-13

    申请号：US13639488

    申请日：2010-09-29

    申请人： Jianhua Chen ,  Yi Huang ,  Junyu Xiong ,  Caihong Chen

    发明人： Jianhua Chen ,  Yi Huang ,  Junyu Xiong ,  Caihong Chen

    IPC分类号： C07K7/08 ,  C07K5/00

    CPC分类号： C07K7/08 ,  A61K38/07 ,  A61K38/10 ,  C07K5/00 ,  C07K5/101

    摘要： Disclosed herein are polypeptides or their derivatives and their application. The polypeptides and their derivatives can treat or prevent cancer. The polypeptides of the invention have significant lethality to the cancer cells when used alone. When its clinical commonly used chemotherapy drugs such as cisplatin in combination, it can significantly increase the sensitivity of chemotherapeutic agents on cancer cells, to enhance its lethality of cancer cells, to reduce the dosage. The peptides can kill a variety of cancer cells, but without apparent toxicity enhancing effect on normal cells. The prepared peptides of the present invention can be chemically synthesized, high-purity, low molecular weight, specificity, non-immunogenic, safe and reliable.

    摘要翻译： 本文公开的是多肽或其衍生物及其应用。 多肽及其衍生物可以治疗或预防癌症。 当单独使用时，本发明的多肽对癌细胞具有显着的致死性。 当其临床常用化疗药物如顺铂联合使用时，可显着增加化疗药对癌细胞的敏感性，增强其对癌细胞的致死性，降低剂量。 肽可以杀死各种癌细胞，但对正常细胞没有明显的毒性增强作用。 本发明制备的肽可以化学合成，高纯度，低分子量，特异性，非免疫原性，安全可靠。

    Method for displaying time on a mobile telephone
    27.
    发明授权
    Method for displaying time on a mobile telephone 有权
    在移动电话上显示时间的方法

    公开(公告)号：US08108006B2

    公开(公告)日：2012-01-31

    申请号：US11720194

    申请日：2005-08-18

    申请人： Guanggang Lin ,  Fangxi Hou ,  Jianhua Chen

    发明人： Guanggang Lin ,  Fangxi Hou ,  Jianhua Chen

    IPC分类号： H04M1/00

    CPC分类号： H04M1/21 ,  H04W52/0254 ,  H04W52/0274 ,  Y02D70/1222 ,  Y02D70/26

    摘要： The present invention relates to a method for time display on a mobile phone. The method includes the following steps: step 1, in a standby state, set a pseudo power off identifier for the mobile phone; step 2, when the mobile phone identifies that the pseudo power off identifier is active, the mobile phone comes into a pseudo power off state; step 3, the mobile phone continually obtains a new time value through a physical layer clock, and displays the new time value on a LCD; and step 4, the mobile phone quits the pseudo power off state, and restarts. The present invention enables the mobile phone to display time without radio frequency signal by setting a third state, i.e., the pseudo power off state.

    摘要翻译： 本发明涉及一种在移动电话上进行时间显示的方法。 该方法包括以下步骤：步骤1，在待机状态下，设置移动电话的伪断电标识符; 步骤2，当手机识别到伪断电标识符为活动状态时，移动电话进入伪断电状态; 步骤3，移动电话通过物理层时钟持续获取新的时间值，并在LCD上显示新的时间值; 步骤4，手机退出伪关机状态，重启。 本发明能够通过设置第三状态即伪电源关闭状态来使无线射频信号显示时间。

    Termal fuse
    28.
    发明申请
    Termal fuse 审中-公开
    术语保险丝

    公开(公告)号：US20110050384A1

    公开(公告)日：2011-03-03

    申请号：US12583981

    申请日：2009-08-27

    申请人： Jianhua Chen ,  Martyn A. Matthiesen ,  Antonio F. Contreras

    发明人： Jianhua Chen ,  Martyn A. Matthiesen ,  Antonio F. Contreras

    IPC分类号： H01H85/06

    CPC分类号： H01H37/761 ,  H01H2037/762 ,  H01H2037/763 ,  H01H2037/768

    摘要： A thermal fuse includes a first contact surface connected to a top surface of a sensor and a bottom surface connected to a bottom surface of the sensor. The sensor includes a mixture of Sn and Zn. The distance between the top surface and the bottom surface of the sensor is sized to substantially limit Zn depletion in a center region of the sensor when a temperature of the sensor is below a melting temperature of the sensor. The center region of the sensor prevents the first contact surface and the second contact surface from separating when the temperature of the sensor is below the melting temperature, and the first contact surface and the second contact surface are configured to separate when the temperature of the center region of the sensor exceeds the melting temperature of the sensor.

    摘要翻译： 热熔丝包括连接到传感器的顶表面的第一接触表面和连接到传感器的底表面的底表面。 传感器包括Sn和Zn的混合物。 当传感器的温度低于传感器的熔化温度时，传感器的顶表面和底表面之间的距离的尺寸被设计成基本上限制传感器中心区域的Zn消耗。 当传感器的温度低于熔化温度时，传感器的中心区域防止第一接触表面和第二接触表面分离，并且第一接触表面和第二接触表面被配置为当中心温度 传感器的区域超过传感器的熔化温度。

    Gas Lighter
    29.
    发明申请
    Gas Lighter 审中-公开
    燃气打火机

    公开(公告)号：US20080014538A1

    公开(公告)日：2008-01-17

    申请号：US11621624

    申请日：2007-01-10

    申请人： Jianhua Chen

    发明人： Jianhua Chen

    IPC分类号： F23D11/36

    CPC分类号： F23Q2/06 ,  F23Q2/36

    摘要： A gas lighter provided with a to a clamping device adapted to improve the coordination between the butane tank and internal units in the cover to simplify the molds required in the manufacturing process includes a hollow tank, a cover, and an internal unit; the tank being articulated by means of a hinge to an end wall on the top of the opening of the tank; and an elastic press member extending from the articulation plate disposed in the tank towards one end at the bottom of the tank; and the elastic press member being matched to the internal unit by tightly compressing it.

    摘要翻译： 设置有夹持装置的气体打火机适于改善丁烷罐和盖中的内部单元之间的配合，以简化制造过程中所需的模具，包括中空罐，盖和内部单元; 罐通过铰链铰接到罐的开口顶部上的端壁; 以及弹性按压构件，其从设置在所述槽中的所述关节板向所述罐的底部的一端延伸; 并且弹性按压构件通过紧密地压缩与内部单元相匹配。