Process for manufacturing a resulting multi-layer pharmaceutical film
    21.
    发明授权
    Process for manufacturing a resulting multi-layer pharmaceutical film 有权
    用于制造所得多层药物膜的方法

    公开(公告)号:US08900498B2

    公开(公告)日:2014-12-02

    申请号:US13974401

    申请日:2013-08-23

    申请人: MonoSol Rx, LLC

    IPC分类号: B29C39/14 B29D7/01

    摘要: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.

    摘要翻译: 本发明涉及其制备的薄膜产品及其制备方法,其表现出非自聚集均匀的异质性。 期望地,膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 膜包含聚合物组分,其包括任选地与亲水性纤维素聚合物共混的聚环氧乙烷。 期望地,膜还含有药物和/或化妆品活性剂,其每单位面积膜的活性剂药物和/或美容活性剂的变化不超过10%。

    Films and Drug Delivery Systems Made Therefrom

    公开(公告)号:US20130333831A1

    公开(公告)日:2013-12-19

    申请号:US13853223

    申请日:2013-03-29

    申请人: MonoSol Rx, LLC

    IPC分类号: A61K31/70 A61K31/715

    摘要: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.

    PACKAGED FILM DOSAGE UNIT CONTAINING A COMPLEXATE
    29.
    发明申请
    PACKAGED FILM DOSAGE UNIT CONTAINING A COMPLEXATE 审中-公开
    包装胶囊剂量单位包含复合物

    公开(公告)号:US20140075894A1

    公开(公告)日:2014-03-20

    申请号:US14064599

    申请日:2013-10-28

    申请人: MonoSol Rx, LLC

    发明人: Richard C. Fuisz

    IPC分类号: B65D79/00 G06Q30/02

    摘要: The present invention relates to packaged orally consumable film dosage units for delivery of actives into the oral cavity. In particular, the packaged pharmaceutical product contains a complexate including a complexing agent and an active, an orally consumable film for delivery of the complexate and a package for containing the orally consumable film. The package includes indicia associated therewith. The indicia identifies the complexate as the active ingredient contained in the film, which is as a regulatory approvable chemical entity. The present invention also relates to methods of labeling, pricing, marketing and satisfying governmental regulations for such packaged pharmaceutical products.

    摘要翻译: 本发明涉及用于将活性物质输送到口腔中的包装的口服消耗膜剂量单位。 特别地,包装的药物包含络合剂,包括络合剂和活性物质,用于递送络合物的口腔消耗性膜和用于容纳口腔消耗性膜的包装。 该包装包括与其相关联的标记。 该标记将复合物鉴定为电影中含有的活性成分,其作为可监管的可批准化学实体。 本发明还涉及标签,定价,营销和满足这种包装药品的政府法规的方法。