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1.
公开(公告)号:US20180177741A1
公开(公告)日:2018-06-28
申请号:US15672228
申请日:2017-08-08
申请人: MonoSol Rx, LLC
IPC分类号: A61K9/70 , C08J5/18 , A61K9/00 , A61K47/44 , A61K47/38 , A61K47/32 , A61K47/22 , A61K47/10 , A61K47/02 , A61K31/80 , A61K31/4545 , A61K31/4525 , A61K31/435 , A61K31/422 , A61K31/192 , A61K47/46 , A61K9/16
CPC分类号: A61K9/7007 , A61K9/0056 , A61K9/006 , A61K9/1635 , A61K9/1652 , A61K9/7015 , A61K31/192 , A61K31/422 , A61K31/435 , A61K31/4525 , A61K31/4545 , A61K31/80 , A61K47/02 , A61K47/10 , A61K47/22 , A61K47/32 , A61K47/38 , A61K47/44 , A61K47/46 , C08J5/18
摘要: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film.
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公开(公告)号:US20180140559A1
公开(公告)日:2018-05-24
申请号:US15865755
申请日:2018-01-09
申请人: MonoSol Rx, LLC
IPC分类号: A61K9/70 , F26B13/20 , A61K8/86 , A23L27/00 , A23P20/20 , A23L33/00 , C08J5/18 , A61Q19/00 , A61Q11/00 , A61K47/38 , A61K47/34 , A61K47/26 , A61K31/4545 , A61K31/192 , A61K9/00 , A61K8/891 , A23L23/10 , A61K8/81 , A61K8/73 , A61K8/49 , A61K8/37 , A61K8/34 , A61K8/02 , A23L2/395 , A23F5/36
CPC分类号: A61K9/7007 , A23F5/36 , A23L2/395 , A23L23/10 , A23L27/72 , A23L33/40 , A23P20/20 , A61K8/0208 , A61K8/0216 , A61K8/0233 , A61K8/34 , A61K8/347 , A61K8/37 , A61K8/498 , A61K8/73 , A61K8/731 , A61K8/8176 , A61K8/86 , A61K8/891 , A61K9/006 , A61K9/7015 , A61K31/192 , A61K31/4545 , A61K47/26 , A61K47/34 , A61K47/38 , A61K2800/592 , A61K2800/594 , A61K2800/92 , A61Q11/00 , A61Q19/00 , C08J5/18 , C08J2371/02 , F26B13/104
摘要: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film. The invention further relates to edible multi-layer films that dissolve in water. In particular, the edible multi-layer films have a first water-soluble film layer and one or more additional water-soluble film layers in at least partial face-to-face engagement with the first film layer.
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3.
公开(公告)号:US09108340B2
公开(公告)日:2015-08-18
申请号:US13974413
申请日:2013-08-23
申请人: MonoSol Rx, LLC
CPC分类号: B29C39/003 , A61J3/00 , A61J2200/20 , A61K9/006 , A61K9/7007 , B29C39/14 , B29C71/02 , F26B13/104
摘要: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.
摘要翻译: 本发明涉及其制备的薄膜产品及其制备方法,其表现出非自聚集均匀的异质性。 期望地,膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 膜包含聚合物组分,其包括任选地与亲水性纤维素聚合物共混的聚环氧乙烷。 期望地,膜还含有药物和/或化妆品活性剂,其每单位面积膜的活性剂药物和/或美容活性剂的变化不超过10%。
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公开(公告)号:US08906277B2
公开(公告)日:2014-12-09
申请号:US13974376
申请日:2013-08-23
申请人: MonoSol Rx, LLC
CPC分类号: A61J3/00 , A61K9/006 , A61K9/7007 , B29C47/0021 , B29C47/8805 , B29C47/8895 , F26B13/10 , F26B13/104
摘要: The invention relates to film products containing desired levels of active components and methods of their preparation. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. Desirably, the films may be exposed to temperatures above that at which the active components typically degrade without concern for loss of the desired activity.
摘要翻译: 本发明涉及含有所需水平的活性成分的薄膜产品及其制备方法。 期望地,膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 期望地,膜可以暴露于高于活性组分通常降解的温度,而不考虑所需活性的损失。
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公开(公告)号:US20140163060A1
公开(公告)日:2014-06-12
申请号:US13890542
申请日:2013-05-09
申请人: MonoSol Rx, LLC
IPC分类号: A61K9/70 , A61K47/08 , A61K47/38 , A61K31/439 , A61K31/352
CPC分类号: A61K9/7007 , A61K9/0056 , A61K31/352 , A61K31/439
摘要: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.
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公开(公告)号:US20140008831A1
公开(公告)日:2014-01-09
申请号:US13974401
申请日:2013-08-23
申请人: MonoSol Rx, LLC
CPC分类号: B29C39/003 , A61J3/00 , A61K9/006 , A61K9/7007 , A61K47/10 , B29C41/26 , B29C71/02 , F26B13/104
摘要: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.
摘要翻译: 本发明涉及其制备的薄膜产品及其制备方法,其表现出非自聚集均匀的异质性。 期望地,膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 膜包含聚合物组分,其包括任选地与亲水性纤维素聚合物共混的聚环氧乙烷。 期望地,膜还含有药物和/或化妆品活性剂,其每单位面积膜的活性剂药物和/或美容活性剂的变化不超过10%。
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公开(公告)号:US20130220526A1
公开(公告)日:2013-08-29
申请号:US13853253
申请日:2013-03-29
申请人: MonoSol Rx, LLC
CPC分类号: A61J3/00 , A61K9/006 , A61K9/2893 , A61K9/7007 , A61K47/10 , F26B13/10 , F26B13/104
摘要: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.
摘要翻译: 本发明涉及其制备的薄膜产品及其制备方法,其表现出非自聚集均匀的异质性。 期望地,膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 膜包含聚合物组分,其包括任选地与亲水性纤维素聚合物共混的聚环氧乙烷。 期望地,膜还含有药物和/或化妆品活性剂,其每单位面积膜的活性剂药物和/或美容活性剂的变化不超过10%。
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公开(公告)号:US20170290777A1
公开(公告)日:2017-10-12
申请号:US15634776
申请日:2017-06-27
申请人: MonoSol Rx, LLC
IPC分类号: A61K9/70 , A61K31/567 , A61K9/50 , A61K31/549 , A61K31/192 , A61K31/138 , A61K31/44 , A61K31/4422 , A61K31/7048 , A61K9/00 , A61K31/4545
CPC分类号: A61K9/7007 , A61K9/0056 , A61K9/006 , A61K9/14 , A61K9/501 , A61K9/5015 , A61K9/5026 , A61K9/5036 , A61K9/5047 , A61K9/7015 , A61K31/138 , A61K31/192 , A61K31/422 , A61K31/44 , A61K31/4422 , A61K31/443 , A61K31/4545 , A61K31/519 , A61K31/549 , A61K31/567 , A61K31/635 , A61K31/704 , A61K31/7048 , A61K47/02 , A61K47/10 , A61K47/22 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/38 , A61K47/44 , A61K47/46 , B05D3/0254 , B29C48/022
摘要: The present invention relates to rapid dissolve thin film drug delivery compositions for the oral administration of active components. The active components are provided as taste-masked or controlled-release coated particles uniformly distributed throughout the film composition. The compositions may be formed by wet casting methods, where the film is cast and controllably dried, or alternatively by an extrusion method.
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公开(公告)号:US20170224628A1
公开(公告)日:2017-08-10
申请号:US15438458
申请日:2017-02-21
申请人: MonoSol Rx, LLC
IPC分类号: A61K9/70 , A61K47/32 , A61K31/567 , A61K31/138 , A61K47/38 , A61K31/44 , A61K31/7048 , A61K31/4545 , A61K31/192 , A61K9/00 , A61K47/34 , A61K31/635
CPC分类号: A61K9/7007 , A61K9/0056 , A61K9/006 , A61K9/14 , A61K9/501 , A61K9/5015 , A61K9/5026 , A61K9/5036 , A61K9/5047 , A61K9/7015 , A61K31/138 , A61K31/192 , A61K31/422 , A61K31/44 , A61K31/4422 , A61K31/443 , A61K31/4545 , A61K31/519 , A61K31/549 , A61K31/567 , A61K31/635 , A61K31/704 , A61K31/7048 , A61K47/02 , A61K47/10 , A61K47/22 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/38 , A61K47/44 , A61K47/46 , B05D3/0254 , B29C47/0004
摘要: The present invention relates to rapid dissolve thin film drug delivery compositions for the oral administration of active components. The active components are provided as taste-masked or controlled-release coated particles uniformly distributed throughout the film composition. The compositions may be formed by wet casting methods, where the film is cast and controllably dried, or alternatively by an extrusion method.
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公开(公告)号:US20160175199A1
公开(公告)日:2016-06-23
申请号:US14980836
申请日:2015-12-28
申请人: MonoSol Rx, LLC
CPC分类号: B29C39/003 , A61J1/035 , B29C41/003 , B29C41/12 , B29C41/28 , B29K2071/02 , B29K2105/0035 , B29K2995/0046 , B29L2007/008 , B65B9/00 , C08J5/18
摘要: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.
摘要翻译: 本发明涉及其制备的薄膜产品及其制备方法,其表现出非自聚集均匀的异质性。 期望地,膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 膜包含聚合物组分,其包括任选地与亲水性纤维素聚合物共混的聚环氧乙烷。 期望地,膜还含有药物和/或化妆品活性剂,其每单位面积膜的活性剂药物和/或美容活性剂的变化不超过10%。
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