Process for manufacturing a resulting multi-layer pharmaceutical film
    9.
    发明授权
    Process for manufacturing a resulting multi-layer pharmaceutical film 有权
    用于制造所得多层药物膜的方法

    公开(公告)号:US09108340B2

    公开(公告)日:2015-08-18

    申请号:US13974413

    申请日:2013-08-23

    申请人: MonoSol Rx, LLC

    摘要: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.

    摘要翻译: 本发明涉及其制备的薄膜产品及其制备方法,其表现出非自聚集均匀的异质性。 期望地,膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 膜包含聚合物组分,其包括任选地与亲水性纤维素聚合物共混的聚环氧乙烷。 期望地,膜还含有药物和/或化妆品活性剂,其每单位面积膜的活性剂药物和/或美容活性剂的变化不超过10%。